MCL coexpression mm9:488
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr11:28630472..28630482,+ | p@chr11:28630472..28630482 + |
| Mm9::chr14:61104032..61104041,+ | p@chr14:61104032..61104041 + |
| Mm9::chr1:24237646..24237669,+ | p@chr1:24237646..24237669 + |
| Mm9::chr3:128897563..128897574,+ | p@chr3:128897563..128897574 + |
| Mm9::chr5:35735487..35735491,+ | p@chr5:35735487..35735491 + |
| Mm9::chr6:70906450..70906454,+ | p1@Foxi3 |
| Mm9::chr6:83660844..83660859,- | p1@Vax2os1 |
| Mm9::chr6:97891135..97891147,+ | p@chr6:97891135..97891147 + |
| Mm9::chr6:97891166..97891186,+ | p@chr6:97891166..97891186 + |
| Mm9::chr6:97891189..97891203,+ | p@chr6:97891189..97891203 + |
| Mm9::chr6:97891221..97891223,+ | p@chr6:97891221..97891223 + |
| Mm9::chr7:94641837..94641850,- | p@chr7:94641837..94641850 - |
| Mm9::chr8:122025598..122025626,- | p1@Slc38a8 |
| Mm9::chr8:122025661..122025666,- | p2@Slc38a8 |
| Mm9::chr9:57976869..57976875,+ | p21@Stra6 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0004503 | monophenol monooxygenase activity | 0.0101895474352689 |
| GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen | 0.0101895474352689 |
| GO:0006583 | melanin biosynthetic process from tyrosine | 0.0203701635264731 |
| GO:0006582 | melanin metabolic process | 0.0203701635264731 |
| GO:0042438 | melanin biosynthetic process | 0.0203701635264731 |
| GO:0006570 | tyrosine metabolic process | 0.022064049524218 |
| GO:0009072 | aromatic amino acid family metabolic process | 0.0330725015878092 |
| GO:0046148 | pigment biosynthetic process | 0.0330725015878092 |
| GO:0042440 | pigment metabolic process | 0.0350415925669434 |
| GO:0030141 | secretory granule | 0.0386439563197676 |
| GO:0019748 | secondary metabolic process | 0.0397424554979222 |
| GO:0005507 | copper ion binding | 0.0457224475371469 |
| GO:0046982 | protein heterodimerization activity | 0.0468793886931207 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| eye | 4.03e-52 | 9 |
| camera-type eye | 4.03e-52 | 9 |
| simple eye | 4.03e-52 | 9 |
| immature eye | 4.03e-52 | 9 |
| ocular region | 4.03e-52 | 9 |
| visual system | 4.03e-52 | 9 |
| face | 4.03e-52 | 9 |
| optic cup | 4.03e-52 | 9 |
| optic vesicle | 4.03e-52 | 9 |
| eye primordium | 4.03e-52 | 9 |
| subdivision of head | 1.38e-42 | 11 |
| sense organ | 5.22e-39 | 12 |
| sensory system | 5.22e-39 | 12 |
| entire sense organ system | 5.22e-39 | 12 |
| head | 5.58e-36 | 13 |
| ectodermal placode | 5.58e-36 | 13 |
| craniocervical region | 1.14e-12 | 36 |
| pre-chordal neural plate | 1.30e-11 | 49 |
| anterior region of body | 1.67e-10 | 43 |
| neurectoderm | 1.06e-08 | 64 |
| neural plate | 1.06e-08 | 64 |
| presumptive neural plate | 1.06e-08 | 64 |
| ecto-epithelium | 1.60e-07 | 73 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.0175753 |
| MA0004.1 | 0.239244 |
| MA0006.1 | 1.2381 |
| MA0007.1 | 0.227553 |
| MA0009.1 | 0.623671 |
| MA0014.1 | 0.0468601 |
| MA0017.1 | 0.832511 |
| MA0019.1 | 1.15568 |
| MA0024.1 | 0.582844 |
| MA0025.1 | 0.845702 |
| MA0027.1 | 2.24512 |
| MA0028.1 | 0.12472 |
| MA0029.1 | 0.562703 |
| MA0030.1 | 0.568779 |
| MA0031.1 | 0.535959 |
| MA0038.1 | 0.358622 |
| MA0040.1 | 0.635404 |
| MA0041.1 | 0.18185 |
| MA0042.1 | 0.172351 |
| MA0043.1 | 0.71494 |
| MA0046.1 | 0.657417 |
| MA0048.1 | 1.11639 |
| MA0050.1 | 0.743895 |
| MA0051.1 | 0.366328 |
| MA0052.1 | 0.642973 |
| MA0055.1 | 6.84559 |
| MA0056.1 | 0 |
| MA0057.1 | 0.431584 |
| MA0058.1 | 0.167504 |
| MA0059.1 | 0.176308 |
| MA0060.1 | 0.071412 |
| MA0061.1 | 0.295622 |
| MA0063.1 | 0 |
| MA0066.1 | 0.921885 |
| MA0067.1 | 0.953264 |
| MA0068.1 | 0.446117 |
| MA0069.1 | 5.11466 |
| MA0070.1 | 0.634186 |
| MA0071.1 | 0.269487 |
| MA0072.1 | 0.626238 |
| MA0073.1 | 0.983598 |
| MA0074.1 | 0.318792 |
| MA0076.1 | 0.148159 |
| MA0077.1 | 0.605975 |
| MA0078.1 | 0.395048 |
| MA0081.1 | 0.193203 |
| MA0083.1 | 0.714187 |
| MA0084.1 | 1.27474 |
| MA0087.1 | 0.673355 |
| MA0088.1 | 1.07775 |
| MA0089.1 | 0 |
| MA0090.1 | 0.212772 |
| MA0091.1 | 0.696557 |
| MA0092.1 | 0.213012 |
| MA0093.1 | 0.130107 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.309116 |
| MA0101.1 | 0.538493 |
| MA0103.1 | 0.439015 |
| MA0105.1 | 0.0373599 |
| MA0106.1 | 0.401864 |
| MA0107.1 | 0.84583 |
| MA0108.2 | 0.476838 |
| MA0109.1 | 0 |
| MA0111.1 | 0.223614 |
| MA0113.1 | 0.377232 |
| MA0114.1 | 0.0864402 |
| MA0115.1 | 0.717599 |
| MA0116.1 | 0.117928 |
| MA0117.1 | 0.686999 |
| MA0119.1 | 0.183219 |
| MA0122.1 | 0.705806 |
| MA0124.1 | 0.901619 |
| MA0125.1 | 0.830088 |
| MA0130.1 | 0 |
| MA0131.1 | 0.452196 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.749615 |
| MA0136.1 | 0.335579 |
| MA0139.1 | 0.0558308 |
| MA0140.1 | 0.30902 |
| MA0141.1 | 0.155997 |
| MA0142.1 | 0.522654 |
| MA0143.1 | 0.391481 |
| MA0144.1 | 0.296781 |
| MA0145.1 | 0.0599431 |
| MA0146.1 | 0.0253534 |
| MA0147.1 | 0.0952713 |
| MA0148.1 | 0.252062 |
| MA0149.1 | 0.18682 |
| MA0062.2 | 0.0394542 |
| MA0035.2 | 0.312946 |
| MA0039.2 | 0.466859 |
| MA0138.2 | 0.445088 |
| MA0002.2 | 0.458095 |
| MA0137.2 | 0.153989 |
| MA0104.2 | 0.0641853 |
| MA0047.2 | 0.357963 |
| MA0112.2 | 0.54155 |
| MA0065.2 | 0.321967 |
| MA0150.1 | 0.644946 |
| MA0151.1 | 0 |
| MA0152.1 | 0.9415 |
| MA0153.1 | 0.765498 |
| MA0154.1 | 0.247047 |
| MA0155.1 | 0.189024 |
| MA0156.1 | 0.147567 |
| MA0157.1 | 0.493416 |
| MA0158.1 | 0 |
| MA0159.1 | 0.679844 |
| MA0160.1 | 0.254455 |
| MA0161.1 | 0 |
| MA0162.1 | 0.00143236 |
| MA0163.1 | 0.0738452 |
| MA0164.1 | 0.335886 |
| MA0080.2 | 0.13897 |
| MA0018.2 | 0.344133 |
| MA0099.2 | 1.1194 |
| MA0079.2 | 1.24442 |
| MA0102.2 | 1.32652 |
| MA0258.1 | 0.967298 |
| MA0259.1 | 0.0890842 |
| MA0442.1 | 0 |
