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{{Coexpression_clusters
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83.1;1.21381,MA0084.1;1.72172,MA0087.1;1.17185,MA0088.1;2.31225,MA0089.1;0,MA0090.1;0.640115,MA0091.1;0.715356,MA0092.1;0.673508,MA0093.1;0.535768,MA0095.1;0,MA0098.1;0,MA0100.1;0.83965,MA0101.1;0.539569,MA0103.1;1.29536,MA0105.1;0.656404,MA0106.1;0.869173,MA0107.1;0.453492,MA0108.2;1.03412,MA0109.1;0,MA0111.1;0.655276,MA0113.1;0.886811,MA0114.1;0.447443,MA0115.1;1.45393,MA0116.1;1.15856,MA0117.1;1.24497,MA0119.1;0.586221,MA0122.1;1.27173,MA0124.1;1.41151,MA0125.1;1.32534,MA0130.1;0,MA0131.1;0.94608,MA0132.1;0,MA0133.1;0,MA0135.1;1.23748,MA0136.1;0.832277,MA0139.1;1.63368,MA0140.1;1.83481,MA0141.1;0.602484,MA0142.1;1.00381,MA0143.1;0.887001,MA0144.1;0.430413,MA0145.1;1.08195,MA0146.1;0.481,MA0147.1;1.16748,MA0148.1;0.739888,MA0149.1;0.769072,MA0062.2;0.931615,MA0035.2;0.778873,MA0039.2;0.483275,MA0138.2;0.928035,MA0002.2;0.379056,MA0137.2;0.558189,MA0104.2;1.01696,MA0047.2;0.856092,MA0112.2;0.187982,MA0065.2;0.199162,MA0150.1;0.633493,MA0151.1;0,MA0152.1;0.78681,MA0153.1;1.30799,MA0154.1;3.48623,MA0155.1;0.180766,MA0156.1;0.560797,MA0157.1;0.97481,MA0158.1;0,MA0159.1;0.462502,MA0160.1;0.756582,MA0161.1;0,MA0162.1;2.80246,MA0163.1;7.0061,MA0164.1;0.90014,MA0080.2;0.535868,MA0018.2;0.870662,MA0099.2;0.7872,MA0079.2;2.72671,MA0102.2;1.75932,MA0258.1;0.418966,MA0259.1;0.471671,MA0442.1;0}}
|full_id=C2039_signet_corpus_optic_spinal_globus_thalamus_medulla
|gostat_on_coexpression_clusters=GO:0005007!fibroblast growth factor receptor activity!0.0261372497981506!2263$GO:0005922!connexon complex!0.0493500129061144!2705$GO:0005921!gap junction!0.0493500129061144!2705
|id=C2039
|ontology_enrichment_celltype=CL:0000148!2.74e-07!10;CL:0000541!2.74e-07!10
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!2.38e-51!115;UBERON:0001049!2.27e-47!57;UBERON:0005068!2.27e-47!57;UBERON:0006241!2.27e-47!57;UBERON:0007135!2.27e-47!57;UBERON:0005743!3.00e-47!86;UBERON:0001017!5.24e-47!82;UBERON:0000073!3.21e-42!94;UBERON:0001016!3.21e-42!94;UBERON:0000955!2.37e-40!69;UBERON:0006238!2.37e-40!69;UBERON:0002616!2.97e-40!59;UBERON:0003080!1.08e-39!42;UBERON:0002780!6.14e-39!41;UBERON:0001890!6.14e-39!41;UBERON:0006240!6.14e-39!41;UBERON:0002020!9.37e-37!34;UBERON:0003528!9.37e-37!34;UBERON:0001893!1.00e-36!34;UBERON:0002791!1.36e-35!33;UBERON:0003075!4.49e-35!86;UBERON:0007284!4.49e-35!86;UBERON:0001869!3.08e-34!32;UBERON:0002346!1.60e-32!90;UBERON:0003056!2.35e-29!61;UBERON:0000153!2.15e-27!129;UBERON:0007811!2.15e-27!129;UBERON:0000033!6.48e-27!123;UBERON:0000956!1.90e-26!25;UBERON:0000203!1.90e-26!25;UBERON:0004121!2.69e-25!169;UBERON:0002619!1.17e-24!22;UBERON:0000924!4.44e-24!173;UBERON:0006601!4.44e-24!173;UBERON:0001950!1.31e-22!20;UBERON:0000025!2.90e-12!194;UBERON:0002308!1.10e-11!9;UBERON:0000125!1.10e-11!9;UBERON:0002420!3.03e-11!9;UBERON:0007245!3.03e-11!9;UBERON:0010009!3.03e-11!9;UBERON:0010011!3.03e-11!9;UBERON:0000454!3.03e-11!9;UBERON:0000062!3.22e-11!511;UBERON:0004111!1.55e-10!241;UBERON:0002298!1.98e-10!8;UBERON:0009663!2.44e-09!7;UBERON:0001871!3.32e-09!7;UBERON:0003076!4.42e-09!15;UBERON:0003057!4.42e-09!15;UBERON:0000475!4.62e-09!365;UBERON:0000064!6.51e-09!219;UBERON:0000477!6.42e-08!286;UBERON:0000200!8.83e-08!6;UBERON:0000483!2.10e-07!309;UBERON:0000481!2.13e-07!347;UBERON:0004732!3.67e-07!13;UBERON:0000119!4.03e-07!312;UBERON:0001872!7.04e-07!5;UBERON:0002021!7.83e-07!5
}}

Latest revision as of 11:57, 17 September 2013


Full id: C2039_signet_corpus_optic_spinal_globus_thalamus_medulla



Phase1 CAGE Peaks

Hg19::chr10:123357854..123357865,-p6@FGFR2
Hg19::chr9:130713012..130713034,-p5@FAM102A
Hg19::chrX:70443019..70443030,+p6@GJB1
Hg19::chrX:70443050..70443061,+p5@GJB1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005007fibroblast growth factor receptor activity0.0261372497981506
GO:0005922connexon complex0.0493500129061144
GO:0005921gap junction0.0493500129061144



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
neural tube2.69e-7356
neural rod2.69e-7356
future spinal cord2.69e-7356
neural keel2.69e-7356
regional part of nervous system1.44e-6653
regional part of brain1.44e-6653
adult organism1.52e-66114
central nervous system9.25e-5981
neural plate3.96e-5682
presumptive neural plate3.96e-5682
regional part of forebrain3.83e-5541
forebrain3.83e-5541
anterior neural tube3.83e-5541
future forebrain3.83e-5541
nervous system2.85e-5489
brain4.36e-5468
future brain4.36e-5468
neurectoderm6.75e-5386
brain grey matter1.35e-5134
gray matter1.35e-5134
telencephalon1.52e-5134
regional part of telencephalon5.61e-4732
cerebral hemisphere8.37e-4732
ecto-epithelium1.69e-43104
pre-chordal neural plate1.65e-4161
structure with developmental contribution from neural crest1.55e-34132
regional part of cerebral cortex1.02e-3322
cerebral cortex3.19e-3225
pallium3.19e-3225
ectoderm-derived structure3.33e-32171
ectoderm3.33e-32171
presumptive ectoderm3.33e-32171
organ system subdivision7.21e-30223
neocortex9.49e-3020
neural nucleus1.33e-219
nucleus of brain1.33e-219
tube4.87e-19192
posterior neural tube2.03e-1815
chordal neural plate2.03e-1815
telencephalic nucleus6.73e-177
anatomical conduit1.27e-16240
basal ganglion1.52e-169
nuclear complex of neuraxis1.52e-169
aggregate regional part of brain1.52e-169
collection of basal ganglia1.52e-169
cerebral subcortex1.52e-169
brainstem1.49e-156
anatomical cluster1.91e-15373
segmental subdivision of nervous system1.84e-1413
parietal lobe2.01e-125
occipital lobe2.11e-125
segmental subdivision of hindbrain2.32e-1212
hindbrain2.32e-1212
presumptive hindbrain2.32e-1212
multi-tissue structure3.18e-12342
organ part1.39e-11218
organ2.44e-10503
gyrus3.06e-106
epithelium3.89e-10306
cell layer6.60e-10309
corpus striatum1.00e-094
striatum1.00e-094
ventral part of telencephalon1.00e-094
future corpus striatum1.00e-094
pons1.09e-083
medulla oblongata1.50e-083
myelencephalon1.50e-083
future myelencephalon1.50e-083
spinal cord1.83e-083
dorsal region element1.83e-083
dorsum1.83e-083
limbic system8.73e-085
caudate-putamen1.29e-073
dorsal striatum1.29e-073
embryo5.26e-07592
regional part of metencephalon9.63e-079
metencephalon9.63e-079
future metencephalon9.63e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.12.92335
MA0004.10.71247
MA0006.10.532262
MA0007.10.6918
MA0009.11.20602
MA0014.10.896009
MA0017.10.577281
MA0019.10.873355
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.10.550763
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.10.732902
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.10.25531
MA0050.10.69864
MA0051.10.820063
MA0052.11.12718
MA0055.10.396851
MA0056.10
MA0057.10.69331
MA0058.10.605914
MA0059.10.604454
MA0060.10.393285
MA0061.10.360128
MA0063.10
MA0066.10.825101
MA0067.11.53181
MA0068.10.313194
MA0069.11.19071
MA0070.11.17908
MA0071.10.782546
MA0072.11.1744
MA0073.10.214613
MA0074.10.819248
MA0076.10.623864
MA0077.11.16637
MA0078.10.926725
MA0081.10.604638
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.12.31225
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.10.673508
MA0093.10.535768
MA0095.10
MA0098.10
MA0100.10.83965
MA0101.10.539569
MA0103.11.29536
MA0105.10.656404
MA0106.10.869173
MA0107.10.453492
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.10.886811
MA0114.10.447443
MA0115.11.45393
MA0116.11.15856
MA0117.11.24497
MA0119.10.586221
MA0122.11.27173
MA0124.11.41151
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.11.63368
MA0140.11.83481
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.11.08195
MA0146.10.481
MA0147.11.16748
MA0148.10.739888
MA0149.10.769072
MA0062.20.931615
MA0035.20.778873
MA0039.20.483275
MA0138.20.928035
MA0002.20.379056
MA0137.20.558189
MA0104.21.01696
MA0047.20.856092
MA0112.20.187982
MA0065.20.199162
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.13.48623
MA0155.10.180766
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.10.462502
MA0160.10.756582
MA0161.10
MA0162.12.80246
MA0163.17.0061
MA0164.10.90014
MA0080.20.535868
MA0018.20.870662
MA0099.20.7872
MA0079.22.72671
MA0102.21.75932
MA0258.10.418966
MA0259.10.471671
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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