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|ontology_enrichment_uberon=UBERON:0000007!3.71e-65!8;UBERON:0003296!3.71e-65!8;UBERON:0010133!3.71e-65!8;UBERON:0001894!2.77e-52!10;UBERON:0006222!2.77e-52!10;UBERON:0002780!7.80e-14!39;UBERON:0001890!7.80e-14!39;UBERON:0006240!7.80e-14!39;UBERON:0003080!1.69e-13!40;UBERON:0002616!8.56e-12!46;UBERON:0000955!1.50e-11!47;UBERON:0006238!1.50e-11!47;UBERON:0003056!4.27e-11!49;UBERON:0001049!1.77e-10!52;UBERON:0005068!1.77e-10!52;UBERON:0006241!1.77e-10!52;UBERON:0007135!1.77e-10!52;UBERON:0000073!4.19e-10!54;UBERON:0002368!3.96e-09!60;UBERON:0002346!1.41e-08!64;UBERON:0003075!1.41e-08!64;UBERON:0007284!1.41e-08!64;UBERON:0002530!1.88e-08!65;UBERON:0000949!1.17e-07!72;UBERON:0010371!1.48e-07!73;UBERON:0001017!1.48e-07!73;UBERON:0001016!2.31e-07!75
|ontology_enrichment_uberon=UBERON:0000007!3.71e-65!8;UBERON:0003296!3.71e-65!8;UBERON:0010133!3.71e-65!8;UBERON:0001894!2.77e-52!10;UBERON:0006222!2.77e-52!10;UBERON:0002780!7.80e-14!39;UBERON:0001890!7.80e-14!39;UBERON:0006240!7.80e-14!39;UBERON:0003080!1.69e-13!40;UBERON:0002616!8.56e-12!46;UBERON:0000955!1.50e-11!47;UBERON:0006238!1.50e-11!47;UBERON:0003056!4.27e-11!49;UBERON:0001049!1.77e-10!52;UBERON:0005068!1.77e-10!52;UBERON:0006241!1.77e-10!52;UBERON:0007135!1.77e-10!52;UBERON:0000073!4.19e-10!54;UBERON:0002368!3.96e-09!60;UBERON:0002346!1.41e-08!64;UBERON:0003075!1.41e-08!64;UBERON:0007284!1.41e-08!64;UBERON:0002530!1.88e-08!65;UBERON:0000949!1.17e-07!72;UBERON:0010371!1.48e-07!73;UBERON:0001017!1.48e-07!73;UBERON:0001016!2.31e-07!75
|tfbs_overrepresentation_for_novel_motifs=0.29262,0.0513547,0.269904,0.329881,0.52369,0.907763,0.425757,0.702429,0.362206,0.208174,0.385334,0.414631,0.106288,0.437133,0.189961,0,0.619876,0.170475,2.19903,0.171249,0.238546,0.117252,0.436294,1.00057,0.276437,0.4628,1.05365,0.949712,0.213277,0.0650265,0.349031,0.717576,0.168723,0.0786762,0.19035,0.0246631,0.161521,0.411296,0.873942,0.123934,0.173534,0.353696,0.478787,0.191571,0.195622,0.319944,0.543674,0.376103,0.081888,0.215702,0.603113,0.488021,0.479906,0.855661,0.87275,0.443782,0.223087,0.40287,1.01274,0.441884,0.698157,0.496904,0.120887,0.592318,0.45416,1.52656,1.00675,1.3527,0.693631,1.20659,0.253722,0.110167,0.0307733,0.905636,0.0810502,0.0742951,0.270351,0.532872,0.681539,0.242107,0.357936,2.60556,0.495545,0.333618,0.792744,0.00855221,0.143445,0.0651072,0.548334,1.51408,1.07554,0.797601,0.730003,1.02436,0.141946,0.129056,0.694736,0.732731,0.543917,0.0534645,0.486605,1.70591,0.838603,0.603683,0.602672,0.353298,0.660145,0.973236,0.246223,0.240055,0.286453,0.840348,0.243062,0.390066,1.0825,0.172131,0.566805,0.333247,1.50549,1.48948,0.910937,0.572279,1.17341,0.532013,1.13603,0.685116,0.433317,0.723425,1.00525,0.183744,0.821997,0.864341,0.976125,0.456508,1.10385,0.2772,0.300001,0.934673,1.05527,1.88134,1.48237,1.01139,0.475785,0.727736,0.596462,0.354106,0.546641,1.84176,3.13045,0.178088,0.0664621,0.0240729,0.857198,0.133365,0.455644,0.93735,0.488969,1.72402,0.290467,0.299755,1.06466,0.791909,0.685546,0.284483,0.593295,1.98996,0.160658,0.413167,0.0207556
|tfbs_overrepresentation_for_novel_motifs=0.29262,0.0513547,0.269904,0.329881,0.52369,0.907763,0.425757,0.702429,0.362206,0.208174,0.385334,0.414631,0.106288,0.437133,0.189961,0,0.619876,0.170475,2.19903,0.171249,0.238546,0.117252,0.436294,1.00057,0.276437,0.4628,1.05365,0.949712,0.213277,0.0650265,0.349031,0.717576,0.168723,0.0786762,0.19035,0.0246631,0.161521,0.411296,0.873942,0.123934,0.173534,0.353696,0.478787,0.191571,0.195622,0.319944,0.543674,0.376103,0.081888,0.215702,0.603113,0.488021,0.479906,0.855661,0.87275,0.443782,0.223087,0.40287,1.01274,0.441884,0.698157,0.496904,0.120887,0.592318,0.45416,1.52656,1.00675,1.3527,0.693631,1.20659,0.253722,0.110167,0.0307733,0.905636,0.0810502,0.0742951,0.270351,0.532872,0.681539,0.242107,0.357936,2.60556,0.495545,0.333618,0.792744,0.00855221,0.143445,0.0651072,0.548334,1.51408,1.07554,0.797601,0.730003,1.02436,0.141946,0.129056,0.694736,0.732731,0.543917,0.0534645,0.486605,1.70591,0.838603,0.603683,0.602672,0.353298,0.660145,0.973236,0.246223,0.240055,0.286453,0.840348,0.243062,0.390066,1.0825,0.172131,0.566805,0.333247,1.50549,1.48948,0.910937,0.572279,1.17341,0.532013,1.13603,0.685116,0.433317,0.723425,1.00525,0.183744,0.821997,0.864341,0.976125,0.456508,1.10385,0.2772,0.300001,0.934673,1.05527,1.88134,1.48237,1.01139,0.475785,0.727736,0.596462,0.354106,0.546641,1.84176,3.13045,0.178088,0.0664621,0.0240729,0.857198,0.133365,0.455644,0.93735,0.488969,1.72402,0.290467,0.299755,1.06466,0.791909,0.685546,0.284483,0.593295,1.98996,0.160658,0.413167,0.0207556
|tfbs_overrepresentation_jaspar=MA0003.1;0.0132247,MA0004.1;0.330313,MA0006.1;0.186435,MA0007.1;0.316976,MA0009.1;2.94487,MA0014.1;0.00333639,MA0017.1;0.207884,MA0019.1;0.567591,MA0024.1;0.70077,MA0025.1;0.971686,MA0027.1;2.37948,MA0028.1;0.194782,MA0029.1;1.62787,MA0030.1;0.686088,MA0031.1;0.651724,MA0038.1;0.462726,MA0040.1;0.755433,MA0041.1;0.263922,MA0042.1;0.252679,MA0043.1;0.837621,MA0046.1;0.778239,MA0048.1;0.440822,MA0050.1;0.365212,MA0051.1;0.471092,MA0052.1;0.76328,MA0055.1;0.136328,MA0056.1;0,MA0057.1;0.048013,MA0058.1;0.246908,MA0059.1;0.257372,MA0060.1;1.28515,MA0061.1;0.451296,MA0063.1;0,MA0066.1;0.452472,MA0067.1;1.08124,MA0068.1;0.0500842,MA0069.1;0.76361,MA0070.1;0.75417,MA0071.1;0.955636,MA0072.1;0.745922,MA0073.1;0.0103656,MA0074.1;0.419185,MA0076.1;0.223625,MA0077.1;0.724865,MA0078.1;0.502121,MA0081.1;0.277253,MA0083.1;0.836845,MA0084.1;1.4063,MA0087.1;0.794721,MA0088.1;0.12124,MA0089.1;0,MA0090.1;0.299987,MA0091.1;1.62354,MA0092.1;0.812369,MA0093.1;0.20148,MA0095.1;0,MA0098.1;0,MA0100.1;0.408523,MA0101.1;0.265031,MA0103.1;0.216742,MA0105.1;0.556739,MA0106.1;0.509454,MA0107.1;0.211681,MA0108.2;0.589413,MA0109.1;0,MA0111.1;0.312463,MA0113.1;0.482899,MA0114.1;0.145642,MA0115.1;0.84036,MA0116.1;0.186271,MA0117.1;0.808813,MA0119.1;0.265536,MA0122.1;0.828211,MA0124.1;1.02871,MA0125.1;0.955734,MA0130.1;0,MA0131.1;0.563262,MA0132.1;0,MA0133.1;0,MA0135.1;0.873285,MA0136.1;0.437601,MA0139.1;0.338099,MA0140.1;1.05203,MA0141.1;0.233109,MA0142.1;0.63775,MA0143.1;0.49828,MA0144.1;0.147954,MA0145.1;0.57264,MA0146.1;0.0833862,MA0147.1;0.157258,MA0148.1;0.344843,MA0149.1;0.269772,MA0062.2;0.271822,MA0035.2;1.06146,MA0039.2;0.00487869,MA0138.2;0.555696,MA0002.2;0.105469,MA0137.2;0.230686,MA0104.2;0.11535,MA0047.2;0.46201,MA0112.2;0.9035,MA0065.2;0.314773,MA0150.1;0.316876,MA0151.1;0,MA0152.1;0.46211,MA0153.1;0.889592,MA0154.1;0.434137,MA0155.1;0.637282,MA0156.1;0.222905,MA0157.1;0.606944,MA0158.1;0,MA0159.1;0.165031,MA0160.1;0.918217,MA0161.1;0,MA0162.1;0.0355033,MA0163.1;0.00559554,MA0164.1;0.437937,MA0080.2;0.609443,MA0018.2;0.446948,MA0099.2;0.549696,MA0079.2;0.000158926,MA0102.2;1.45844,MA0258.1;0.421574,MA0259.1;0.14914,MA0442.1;0
}}
}}

Revision as of 12:03, 23 January 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:110991047..110991081,+p@chr10:110991047..110991081
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Mm9::chr16:65521021..65521032,+p2@Pou1f1
Mm9::chr2:157397171..157397183,-p14@Blcap
Mm9::chr2:163862718..163862732,+p4@Pabpc1l
Mm9::chr2:26060097..26060110,-p@chr2:26060097..26060110
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Mm9::chr2:26060131..26060142,-p@chr2:26060131..26060142
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Mm9::chr2:26060145..26060156,-p@chr2:26060145..26060156
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Mm9::chr2:26060176..26060181,-p@chr2:26060176..26060181
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Mm9::chr5:5314581..5314592,-p@chr5:5314581..5314592
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Mm9::chr6:119217479..119217523,+p@chr6:119217479..119217523
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Mm9::chrX:139493649..139493658,+p@chrX:139493649..139493658
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0032962positive regulation of inositol trisphosphate biosynthetic process0.00375270495224433
GO:0032959inositol trisphosphate biosynthetic process0.00375270495224433
GO:0032958inositol phosphate biosynthetic process0.00375270495224433
GO:0032960regulation of inositol trisphosphate biosynthetic process0.00375270495224433
GO:0006021inositol biosynthetic process0.00375270495224433
GO:0043647inositol phosphate metabolic process0.00375270495224433
GO:0032957inositol trisphosphate metabolic process0.00375270495224433
GO:0060133somatotropin secreting cell development0.00375270495224433
GO:0060126somatotropin secreting cell differentiation0.00450312257623173
GO:0043567regulation of insulin-like growth factor receptor signaling pathway0.00450312257623173
GO:0045913positive regulation of carbohydrate metabolic process0.0050033324553003
GO:0043255regulation of carbohydrate biosynthetic process0.0050033324553003
GO:0006109regulation of carbohydrate metabolic process0.00643250353835337
GO:0021984adenohypophysis development0.00643250353835337
GO:0008340determination of adult life span0.00700408972726694
GO:0048009insulin-like growth factor receptor signaling pathway0.00794538066611113
GO:0006020inositol metabolic process0.00794538066611113
GO:0010259multicellular organismal aging0.00833751668703983
GO:0021983pituitary gland development0.0142145434083468
GO:0021536diencephalon development0.0150009504920605
GO:0040018positive regulation of multicellular organism growth0.0150009504920605
GO:0001708cell fate specification0.0150009504920605
GO:0019319hexose biosynthetic process0.0150009504920605
GO:0046165alcohol biosynthetic process0.0150009504920605
GO:0046364monosaccharide biosynthetic process0.0150009504920605
GO:0045927positive regulation of growth0.0150009504920605
GO:0007568aging0.0155556883470946
GO:0030183B cell differentiation0.0187465618727708
GO:0035270endocrine system development0.0248141852991228
GO:0040014regulation of multicellular organism growth0.0259831151355832
GO:0035264multicellular organism growth0.0294896781300526
GO:0048732gland development0.0346440524221495
GO:0016051carbohydrate biosynthetic process0.0358591910391614
GO:0042113B cell activation0.0374417210532664
GO:0030098lymphocyte differentiation0.0393597288025601
GO:0003682chromatin binding0.0393961055216672
GO:0030900forebrain development0.0393961055216672
GO:0045165cell fate commitment0.0393961055216672
GO:0002521leukocyte differentiation0.0486140962192843
GO:0019318hexose metabolic process0.0486140962192843
GO:0005996monosaccharide metabolic process0.0488823455569572
GO:0031326regulation of cellular biosynthetic process0.0494922157546636



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
pituitary gland3.71e-658
gland of diencephalon3.71e-658
neuroendocrine gland3.71e-658
diencephalon2.77e-5210
future diencephalon2.77e-5210
regional part of forebrain7.80e-1439
forebrain7.80e-1439
future forebrain7.80e-1439
anterior neural tube1.69e-1340
regional part of brain8.56e-1246
brain1.50e-1147
future brain1.50e-1147
pre-chordal neural plate4.27e-1149
neural tube1.77e-1052
neural rod1.77e-1052
future spinal cord1.77e-1052
neural keel1.77e-1052
regional part of nervous system4.19e-1054
endocrine gland3.96e-0960
neurectoderm1.41e-0864
neural plate1.41e-0864
presumptive neural plate1.41e-0864
gland1.88e-0865
endocrine system1.17e-0772
ecto-epithelium1.48e-0773
central nervous system1.48e-0773
nervous system2.31e-0775


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0132247
MA0004.10.330313
MA0006.10.186435
MA0007.10.316976
MA0009.12.94487
MA0014.10.00333639
MA0017.10.207884
MA0019.10.567591
MA0024.10.70077
MA0025.10.971686
MA0027.12.37948
MA0028.10.194782
MA0029.11.62787
MA0030.10.686088
MA0031.10.651724
MA0038.10.462726
MA0040.10.755433
MA0041.10.263922
MA0042.10.252679
MA0043.10.837621
MA0046.10.778239
MA0048.10.440822
MA0050.10.365212
MA0051.10.471092
MA0052.10.76328
MA0055.10.136328
MA0056.10
MA0057.10.048013
MA0058.10.246908
MA0059.10.257372
MA0060.11.28515
MA0061.10.451296
MA0063.10
MA0066.10.452472
MA0067.11.08124
MA0068.10.0500842
MA0069.10.76361
MA0070.10.75417
MA0071.10.955636
MA0072.10.745922
MA0073.10.0103656
MA0074.10.419185
MA0076.10.223625
MA0077.10.724865
MA0078.10.502121
MA0081.10.277253
MA0083.10.836845
MA0084.11.4063
MA0087.10.794721
MA0088.10.12124
MA0089.10
MA0090.10.299987
MA0091.11.62354
MA0092.10.812369
MA0093.10.20148
MA0095.10
MA0098.10
MA0100.10.408523
MA0101.10.265031
MA0103.10.216742
MA0105.10.556739
MA0106.10.509454
MA0107.10.211681
MA0108.20.589413
MA0109.10
MA0111.10.312463
MA0113.10.482899
MA0114.10.145642
MA0115.10.84036
MA0116.10.186271
MA0117.10.808813
MA0119.10.265536
MA0122.10.828211
MA0124.11.02871
MA0125.10.955734
MA0130.10
MA0131.10.563262
MA0132.10
MA0133.10
MA0135.10.873285
MA0136.10.437601
MA0139.10.338099
MA0140.11.05203
MA0141.10.233109
MA0142.10.63775
MA0143.10.49828
MA0144.10.147954
MA0145.10.57264
MA0146.10.0833862
MA0147.10.157258
MA0148.10.344843
MA0149.10.269772
MA0062.20.271822
MA0035.21.06146
MA0039.20.00487869
MA0138.20.555696
MA0002.20.105469
MA0137.20.230686
MA0104.20.11535
MA0047.20.46201
MA0112.20.9035
MA0065.20.314773
MA0150.10.316876
MA0151.10
MA0152.10.46211
MA0153.10.889592
MA0154.10.434137
MA0155.10.637282
MA0156.10.222905
MA0157.10.606944
MA0158.10
MA0159.10.165031
MA0160.10.918217
MA0161.10
MA0162.10.0355033
MA0163.10.00559554
MA0164.10.437937
MA0080.20.609443
MA0018.20.446948
MA0099.20.549696
MA0079.20.000158926
MA0102.21.45844
MA0258.10.421574
MA0259.10.14914
MA0442.10
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