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Coexpression cluster:C2225: Difference between revisions

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|ontology_enrichment_uberon=UBERON:0007023!6.59e-50!114;UBERON:0001049!4.30e-17!56;UBERON:0005068!4.30e-17!56;UBERON:0006241!4.30e-17!56;UBERON:0007135!4.30e-17!56;UBERON:0011216!1.67e-15!223;UBERON:0001017!2.83e-15!81;UBERON:0003075!4.91e-15!82;UBERON:0007284!4.91e-15!82;UBERON:0002346!1.08e-14!86;UBERON:0000073!1.18e-14!53;UBERON:0002616!1.18e-14!53;UBERON:0000481!2.69e-13!342;UBERON:0001893!3.72e-13!34;UBERON:0010314!1.11e-12!132;UBERON:0001016!1.33e-12!89;UBERON:0000955!1.49e-12!68;UBERON:0006238!1.49e-12!68;UBERON:0002780!4.38e-12!41;UBERON:0001890!4.38e-12!41;UBERON:0003080!4.38e-12!41;UBERON:0006240!4.38e-12!41;UBERON:0003528!6.83e-12!34;UBERON:0002020!6.83e-12!34;UBERON:0010371!7.09e-12!104;UBERON:0001869!9.07e-12!32;UBERON:0002791!1.10e-11!32;UBERON:0000468!1.47e-11!656;UBERON:0000922!2.56e-11!592;UBERON:0000477!1.03e-10!373;UBERON:0004121!5.21e-10!171;UBERON:0000924!5.21e-10!171;UBERON:0006601!5.21e-10!171;UBERON:0000062!2.33e-09!503;UBERON:0005423!2.57e-09!581;UBERON:0002050!3.19e-09!564;UBERON:0003056!3.73e-09!61;UBERON:0000923!5.52e-09!560;UBERON:0010316!5.52e-09!560;UBERON:0005291!5.52e-09!560;UBERON:0006598!5.52e-09!560;UBERON:0010317!5.52e-09!560;UBERON:0002532!5.52e-09!560;UBERON:0000956!7.52e-09!25;UBERON:0000203!7.52e-09!25;UBERON:0005409!8.08e-08!25;UBERON:0000160!9.73e-08!17;UBERON:0000467!1.98e-07!624;UBERON:0000059!1.98e-07!11;UBERON:0000480!2.30e-07!625;UBERON:0001155!3.55e-07!9;UBERON:0002619!8.02e-07!22
|ontology_enrichment_uberon=UBERON:0007023!6.59e-50!114;UBERON:0001049!4.30e-17!56;UBERON:0005068!4.30e-17!56;UBERON:0006241!4.30e-17!56;UBERON:0007135!4.30e-17!56;UBERON:0011216!1.67e-15!223;UBERON:0001017!2.83e-15!81;UBERON:0003075!4.91e-15!82;UBERON:0007284!4.91e-15!82;UBERON:0002346!1.08e-14!86;UBERON:0000073!1.18e-14!53;UBERON:0002616!1.18e-14!53;UBERON:0000481!2.69e-13!342;UBERON:0001893!3.72e-13!34;UBERON:0010314!1.11e-12!132;UBERON:0001016!1.33e-12!89;UBERON:0000955!1.49e-12!68;UBERON:0006238!1.49e-12!68;UBERON:0002780!4.38e-12!41;UBERON:0001890!4.38e-12!41;UBERON:0003080!4.38e-12!41;UBERON:0006240!4.38e-12!41;UBERON:0003528!6.83e-12!34;UBERON:0002020!6.83e-12!34;UBERON:0010371!7.09e-12!104;UBERON:0001869!9.07e-12!32;UBERON:0002791!1.10e-11!32;UBERON:0000468!1.47e-11!656;UBERON:0000922!2.56e-11!592;UBERON:0000477!1.03e-10!373;UBERON:0004121!5.21e-10!171;UBERON:0000924!5.21e-10!171;UBERON:0006601!5.21e-10!171;UBERON:0000062!2.33e-09!503;UBERON:0005423!2.57e-09!581;UBERON:0002050!3.19e-09!564;UBERON:0003056!3.73e-09!61;UBERON:0000923!5.52e-09!560;UBERON:0010316!5.52e-09!560;UBERON:0005291!5.52e-09!560;UBERON:0006598!5.52e-09!560;UBERON:0010317!5.52e-09!560;UBERON:0002532!5.52e-09!560;UBERON:0000956!7.52e-09!25;UBERON:0000203!7.52e-09!25;UBERON:0005409!8.08e-08!25;UBERON:0000160!9.73e-08!17;UBERON:0000467!1.98e-07!624;UBERON:0000059!1.98e-07!11;UBERON:0000480!2.30e-07!625;UBERON:0001155!3.55e-07!9;UBERON:0002619!8.02e-07!22
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}}
}}

Revision as of 15:22, 26 November 2012


Full id: C2225_uterus_smooth_ductus_cervix_prostate_heart_umbilical



Phase1 CAGE Peaks

Hg19::chr12:58003893..58003906,+p6@ARHGEF25
Hg19::chr12:58003916..58003927,+p8@ARHGEF25
Hg19::chr12:58003935..58003967,+p4@ARHGEF25
Hg19::chr12:58004058..58004075,+p5@ARHGEF25


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism6.59e-50114
neural tube4.30e-1756
neural rod4.30e-1756
future spinal cord4.30e-1756
neural keel4.30e-1756
organ system subdivision1.67e-15223
central nervous system2.83e-1581
neural plate4.91e-1582
presumptive neural plate4.91e-1582
neurectoderm1.08e-1486
regional part of nervous system1.18e-1453
regional part of brain1.18e-1453
multi-tissue structure2.69e-13342
telencephalon3.72e-1334
structure with developmental contribution from neural crest1.11e-12132
nervous system1.33e-1289
brain1.49e-1268
future brain1.49e-1268
regional part of forebrain4.38e-1241
forebrain4.38e-1241
anterior neural tube4.38e-1241
future forebrain4.38e-1241
brain grey matter6.83e-1234
gray matter6.83e-1234
ecto-epithelium7.09e-12104
cerebral hemisphere9.07e-1232
regional part of telencephalon1.10e-1132
multi-cellular organism1.47e-11656
embryo2.56e-11592
anatomical cluster1.03e-10373
ectoderm-derived structure5.21e-10171
ectoderm5.21e-10171
presumptive ectoderm5.21e-10171
organ2.33e-09503
developing anatomical structure2.57e-09581
embryonic structure3.19e-09564
pre-chordal neural plate3.73e-0961
germ layer5.52e-09560
germ layer / neural crest5.52e-09560
embryonic tissue5.52e-09560
presumptive structure5.52e-09560
germ layer / neural crest derived structure5.52e-09560
epiblast (generic)5.52e-09560
cerebral cortex7.52e-0925
pallium7.52e-0925
gastrointestinal system8.08e-0825
intestine9.73e-0817
anatomical system1.98e-07624
large intestine1.98e-0711
anatomical group2.30e-07625
colon3.55e-079
regional part of cerebral cortex8.02e-0722


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.