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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000080!5.78e-11!18;UBERON:0002120!5.78e-11!18;UBERON:0004875!5.78e-11!18;UBERON:0005721!5.78e-11!18;UBERON:0005754!5.78e-11!18;UBERON:0007297!5.78e-11!18;UBERON:0006555!8.69e-11!17;UBERON:0005103!8.69e-11!17;UBERON:0000083!8.69e-11!17;UBERON:0009201!8.69e-11!17;UBERON:0004819!8.69e-11!17;UBERON:0006553!8.69e-11!17;UBERON:0003074!8.69e-11!17;UBERON:0003060!8.69e-11!17;UBERON:0004211!1.62e-10!16;UBERON:0001285!1.62e-10!16;UBERON:0007684!1.62e-10!16;UBERON:0003220!1.62e-10!16;UBERON:0004208!1.62e-10!16;UBERON:0004876!3.33e-10!20;UBERON:0003887!1.61e-09!21;UBERON:0001225!1.21e-08!13;UBERON:0008987!1.21e-08!13;UBERON:0009773!8.53e-08!12;UBERON:0001231!8.53e-08!12;UBERON:0004810!8.53e-08!12;UBERON:0001008!4.36e-07!45;UBERON:0000058!4.54e-07!26;UBERON:0006554!6.51e-07!44
|ontology_enrichment_uberon=UBERON:0000080!5.78e-11!18;UBERON:0002120!5.78e-11!18;UBERON:0004875!5.78e-11!18;UBERON:0005721!5.78e-11!18;UBERON:0005754!5.78e-11!18;UBERON:0007297!5.78e-11!18;UBERON:0006555!8.69e-11!17;UBERON:0005103!8.69e-11!17;UBERON:0000083!8.69e-11!17;UBERON:0009201!8.69e-11!17;UBERON:0004819!8.69e-11!17;UBERON:0006553!8.69e-11!17;UBERON:0003074!8.69e-11!17;UBERON:0003060!8.69e-11!17;UBERON:0004211!1.62e-10!16;UBERON:0001285!1.62e-10!16;UBERON:0007684!1.62e-10!16;UBERON:0003220!1.62e-10!16;UBERON:0004208!1.62e-10!16;UBERON:0004876!3.33e-10!20;UBERON:0003887!1.61e-09!21;UBERON:0001225!1.21e-08!13;UBERON:0008987!1.21e-08!13;UBERON:0009773!8.53e-08!12;UBERON:0001231!8.53e-08!12;UBERON:0004810!8.53e-08!12;UBERON:0001008!4.36e-07!45;UBERON:0000058!4.54e-07!26;UBERON:0006554!6.51e-07!44
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}}
}}

Revision as of 19:35, 8 August 2012


Full id: C3957_Alveolar_testicular_merkel_oral_carcinoid_mesothelioma_choriocarcinoma



Phase1 CAGE Peaks

Hg19::chr1:243651053..243651073,+p4@SDCCAG8
Hg19::chr1:243651083..243651106,+p3@SDCCAG8
Hg19::chr1:243651108..243651152,+p2@SDCCAG8


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
epithelial cell of nephron1.62e-1016
kidney cortical cell1.21e-0813
renal cortical epithelial cell1.21e-0813
kidney cell1.58e-0818
kidney epithelial cell1.58e-0818
epithelial cell6.24e-08254
kidney tubule cell8.53e-0812
nephron tubule epithelial cell8.53e-0812
germ line cell6.31e-077
germ cell6.31e-077
Uber Anatomy
Ontology termp-valuen
mesonephros5.78e-1118
pronephros5.78e-1118
nephrogenic cord5.78e-1118
pronephric mesoderm5.78e-1118
rostral part of nephrogenic cord5.78e-1118
presumptive pronephric mesoderm5.78e-1118
excretory tube8.69e-1117
mesonephric epithelium8.69e-1117
mesonephric tubule8.69e-1117
nephric duct8.69e-1117
kidney epithelium8.69e-1117
renal duct8.69e-1117
mesonephric duct8.69e-1117
pronephric duct8.69e-1117
nephron epithelium1.62e-1016
nephron1.62e-1016
uriniferous tubule1.62e-1016
metanephric mesenchyme1.62e-1016
nephrogenic mesenchyme1.62e-1016
urogenital ridge3.33e-1020
intraembryonic coelom1.61e-0921
cortex of kidney1.21e-0813
renal parenchyma1.21e-0813
renal tubule8.53e-0812
nephron tubule8.53e-0812
nephron tubule epithelium8.53e-0812
renal system4.36e-0745
duct4.54e-0726
urinary system structure6.51e-0744


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.