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MCL coexpression mm9:865

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:57834341..57834352,+p@chr10:57834341..57834352
+
Mm9::chr10:57834358..57834375,+p@chr10:57834358..57834375
+
Mm9::chr16:95479917..95479940,+p7@Kcnj15
Mm9::chr16:95479946..95479978,+p3@Kcnj15
Mm9::chr16:95479979..95480004,+p8@Kcnj15
Mm9::chr16:95481305..95481317,-p2@uc008abr.1
Mm9::chr6:125271351..125271378,+p1@Scnn1a
Mm9::chr9:62345663..62345675,-p@chr9:62345663..62345675
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0031420alkali metal ion binding0.00925754197162571
GO:0005261cation channel activity0.00925754197162571
GO:0022836gated channel activity0.00925754197162571
GO:0046873metal ion transmembrane transporter activity0.00925754197162571
GO:0015672monovalent inorganic cation transport0.00925754197162571
GO:0005216ion channel activity0.00925754197162571
GO:0022838substrate specific channel activity0.00925754197162571
GO:0015280amiloride-sensitive sodium channel activity0.00925754197162571
GO:0022803passive transmembrane transporter activity0.00925754197162571
GO:0015267channel activity0.00925754197162571
GO:0030001metal ion transport0.00925754197162571
GO:0008324cation transmembrane transporter activity0.0108821324932122
GO:0006812cation transport0.0108821324932122
GO:0005242inward rectifier potassium channel activity0.0124822025107478
GO:0015075ion transmembrane transporter activity0.0169669351270431
GO:0007163establishment and/or maintenance of cell polarity0.0169669351270431
GO:0006811ion transport0.0169669351270431
GO:0005272sodium channel activity0.0169669351270431
GO:0005925focal adhesion0.0169669351270431
GO:0022891substrate-specific transmembrane transporter activity0.0169669351270431
GO:0005924cell-substrate adherens junction0.0178595483766892
GO:0043169cation binding0.0178595483766892
GO:0030055cell-matrix junction0.0188918977019955
GO:0022857transmembrane transporter activity0.0188918977019955
GO:0046872metal ion binding0.0195826589729386
GO:0043167ion binding0.0195826589729386
GO:0022892substrate-specific transporter activity0.0195826589729386
GO:0050909sensory perception of taste0.0195826589729386
GO:0005912adherens junction0.0261422989106417
GO:0007160cell-matrix adhesion0.0261422989106417
GO:0031589cell-substrate adhesion0.0268993818387301
GO:0016323basolateral plasma membrane0.0272211068508857
GO:0031402sodium ion binding0.0286697266025328
GO:0005249voltage-gated potassium channel activity0.0286697266025328
GO:0015276ligand-gated ion channel activity0.0286697266025328
GO:0022834ligand-gated channel activity0.0286697266025328
GO:0030955potassium ion binding0.0365924190780974
GO:0006814sodium ion transport0.0365924190780974
GO:0022843voltage-gated cation channel activity0.036919405717662
GO:0005267potassium channel activity0.0378458342033089
GO:0006813potassium ion transport0.0462260026767222
GO:0022832voltage-gated channel activity0.0480720549348637
GO:0005244voltage-gated ion channel activity0.0480720549348637



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
respiratory system4.08e-1242
respiratory tract1.64e-1141
lung1.26e-0914
respiratory tube1.26e-0914
respiration organ1.26e-0914
pair of lungs1.26e-0914
lung primordium1.26e-0914
lung bud1.26e-0914
epithelial bud2.85e-0917
foregut5.86e-0980
thoracic cavity element3.56e-0717
thoracic segment organ3.56e-0717
thoracic cavity3.56e-0717
thoracic segment of trunk3.56e-0717
respiratory primordium3.56e-0717
endoderm of foregut3.56e-0717
epithelial fold3.61e-0720


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0545917
MA0004.11.10905
MA0006.10.747445
MA0007.10.419994
MA0009.10.870101
MA0014.10.012738
MA0017.10.296816
MA0019.10.688051
MA0024.10.826339
MA0025.11.10341
MA0027.12.51754
MA0028.10.281528
MA0029.10.804619
MA0030.10.811181
MA0031.10.775627
MA0038.10.577528
MA0040.10.882616
MA0041.10.360875
MA0042.10.348174
MA0043.10.966833
MA0046.10.906029
MA0048.10.102483
MA0050.10.472794
MA0051.10.586414
MA0052.10.890676
MA0055.10.117901
MA0056.10
MA0057.11.58436
MA0058.11.62198
MA0059.12.51175
MA0060.10.197678
MA0061.10.224905
MA0063.10
MA0066.11.39085
MA0067.11.21448
MA0068.10.0965831
MA0069.10.891016
MA0070.10.881319
MA0071.10.471969
MA0072.10.872842
MA0073.10.138438
MA0074.10.531046
MA0076.10.315013
MA0077.10.851175
MA0078.10.61926
MA0081.10.980744
MA0083.10.96604
MA0084.11.54225
MA0087.10.922929
MA0088.10.853781
MA0089.10
MA0090.10.401197
MA0091.10.447561
MA0092.10.401504
MA0093.11.43515
MA0095.10
MA0098.10
MA0100.10.519598
MA0101.10.362124
MA0103.10.827743
MA0105.10.133231
MA0106.10.626997
MA0107.10.301222
MA0108.20.710846
MA0109.10
MA0111.10.415012
MA0113.10.598933
MA0114.10.222763
MA0115.10.969632
MA0116.10.747001
MA0117.10.937363
MA0119.10.362692
MA0122.10.957212
MA0124.11.16127
MA0125.11.0872
MA0130.10
MA0131.10.683521
MA0132.10
MA0133.10
MA0135.11.00325
MA0136.11.35732
MA0139.10.169849
MA0140.10.519484
MA0141.10.325895
MA0142.10.761136
MA0143.10.615203
MA0144.10.225588
MA0145.10.527241
MA0146.10.198184
MA0147.11.24068
MA0148.10.450593
MA0149.10.367458
MA0062.20.137653
MA0035.21.30087
MA0039.20.027551
MA0138.20.675599
MA0002.20.988033
MA0137.20.32312
MA0104.20.54394
MA0047.20.576767
MA0112.20.0701537
MA0065.20.902537
MA0150.10.419883
MA0151.10
MA0152.10.576873
MA0153.11.01988
MA0154.10.330759
MA0155.10.0804339
MA0156.10.843735
MA0157.10.729116
MA0158.10
MA0159.10.246253
MA0160.10.453546
MA0161.10
MA0162.10.0925951
MA0163.10.408151
MA0164.10.551114
MA0080.21.48111
MA0018.20.560731
MA0099.20.669311
MA0079.21.19114
MA0102.21.59466
MA0258.10.210437
MA0259.10.227035
MA0442.10
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