MCL coexpression mm9:484
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr10:94977804..94977814,+ | p4@Mcg1038069 p4@Ube2n |
| Mm9::chr11:3024046..3024057,+ | p3@Pisd-ps3 |
| Mm9::chr15:91537149..91537152,+ | p@chr15:91537149..91537152 + |
| Mm9::chr18:35931228..35931253,+ | p4@Ube2d2 |
| Mm9::chr18:35931264..35931269,+ | p8@Ube2d2 |
| Mm9::chr19:61242876..61242882,+ | p@chr19:61242876..61242882 + |
| Mm9::chr19:9633694..9633738,- | p1@ENSMUST00000090527 |
| Mm9::chr1:107352544..107352553,+ | p1@ENSMUST00000086725 |
| Mm9::chr1:4761175..4761203,+ | p@chr1:4761175..4761203 + |
| Mm9::chr3:92493213..92493228,+ | p@chr3:92493213..92493228 + |
| Mm9::chr3:92493229..92493259,+ | p1@ENSMUST00000169025 |
| Mm9::chr4:103235928..103235936,+ | p1@ENSMUST00000079345 |
| Mm9::chr5:8971911..8971920,+ | p1@ENSMUST00000104982 |
| Mm9::chr6:46994593..46994618,+ | p6@Cntnap2 |
| Mm9::chr9:62257059..62257102,+ | p@chr9:62257059..62257102 + |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0004842 | ubiquitin-protein ligase activity | 0.00128265225111418 |
| GO:0008639 | small protein conjugating enzyme activity | 0.00128265225111418 |
| GO:0019787 | small conjugating protein ligase activity | 0.00128265225111418 |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 0.00128265225111418 |
| GO:0043632 | modification-dependent macromolecule catabolic process | 0.00128265225111418 |
| GO:0019941 | modification-dependent protein catabolic process | 0.00128265225111418 |
| GO:0051603 | proteolysis involved in cellular protein catabolic process | 0.00128265225111418 |
| GO:0044257 | cellular protein catabolic process | 0.00128265225111418 |
| GO:0016881 | acid-amino acid ligase activity | 0.00128265225111418 |
| GO:0016879 | ligase activity, forming carbon-nitrogen bonds | 0.00175439577964413 |
| GO:0030163 | protein catabolic process | 0.00193202443631754 |
| GO:0044265 | cellular macromolecule catabolic process | 0.00284655464124699 |
| GO:0043285 | biopolymer catabolic process | 0.00284655464124699 |
| GO:0009057 | macromolecule catabolic process | 0.0042178770412939 |
| GO:0016874 | ligase activity | 0.00481300063153218 |
| GO:0044248 | cellular catabolic process | 0.00718152715250053 |
| GO:0006512 | ubiquitin cycle | 0.00774700785183523 |
| GO:0051092 | activation of NF-kappaB transcription factor | 0.0099638634077022 |
| GO:0009056 | catabolic process | 0.010013119315629 |
| GO:0050852 | T cell receptor signaling pathway | 0.0115270861488087 |
| GO:0006508 | proteolysis | 0.0116422451271434 |
| GO:0051091 | positive regulation of transcription factor activity | 0.0116422451271434 |
| GO:0051090 | regulation of transcription factor activity | 0.0139162613497778 |
| GO:0050851 | antigen receptor-mediated signaling pathway | 0.0144017515599351 |
| GO:0002429 | immune response-activating cell surface receptor signaling pathway | 0.0163815022618512 |
| GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 0.0167340748867441 |
| GO:0002757 | immune response-activating signal transduction | 0.017060323285079 |
| GO:0002764 | immune response-regulating signal transduction | 0.0173630679316928 |
| GO:0002253 | activation of immune response | 0.0338972660671632 |
| GO:0043687 | post-translational protein modification | 0.0346689203717076 |
| GO:0050778 | positive regulation of immune response | 0.0390523850299093 |
| GO:0002684 | positive regulation of immune system process | 0.0390523850299093 |
| GO:0006464 | protein modification process | 0.0392211885276638 |
| GO:0005515 | protein binding | 0.0392211885276638 |
| GO:0050776 | regulation of immune response | 0.0392211885276638 |
| GO:0002682 | regulation of immune system process | 0.0392211885276638 |
| GO:0043412 | biopolymer modification | 0.0392211885276638 |
| GO:0051240 | positive regulation of multicellular organismal process | 0.0392211885276638 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| connective tissue | 1.08e-17 | 46 |
| mucosa | 9.69e-16 | 15 |
| intestinal mucosa | 8.55e-13 | 13 |
| anatomical wall | 8.55e-13 | 13 |
| wall of intestine | 8.55e-13 | 13 |
| gastrointestinal system mucosa | 8.55e-13 | 13 |
| simple columnar epithelium | 2.02e-12 | 11 |
| epithelium of mucosa | 9.49e-11 | 9 |
| gastrointestinal system epithelium | 9.49e-11 | 9 |
| intestinal epithelium | 9.49e-11 | 9 |
| organ component layer | 1.99e-08 | 24 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.446578 |
| MA0004.1 | 0.239244 |
| MA0006.1 | 0.118059 |
| MA0007.1 | 0.227553 |
| MA0009.1 | 0.623671 |
| MA0014.1 | 1.41021 |
| MA0017.1 | 0.135289 |
| MA0019.1 | 0.456268 |
| MA0024.1 | 0.582844 |
| MA0025.1 | 0.845702 |
| MA0027.1 | 2.24512 |
| MA0028.1 | 0.12472 |
| MA0029.1 | 0.562703 |
| MA0030.1 | 0.568779 |
| MA0031.1 | 0.535959 |
| MA0038.1 | 0.358622 |
| MA0040.1 | 0.635404 |
| MA0041.1 | 0.18185 |
| MA0042.1 | 0.172351 |
| MA0043.1 | 0.71494 |
| MA0046.1 | 0.657417 |
| MA0048.1 | 0.102771 |
| MA0050.1 | 0.270164 |
| MA0051.1 | 0.366328 |
| MA0052.1 | 0.642973 |
| MA0055.1 | 0.381798 |
| MA0056.1 | 0 |
| MA0057.1 | 0.703408 |
| MA0058.1 | 0.167504 |
| MA0059.1 | 0.176308 |
| MA0060.1 | 0.249987 |
| MA0061.1 | 0.615538 |
| MA0063.1 | 0 |
| MA0066.1 | 0.349199 |
| MA0067.1 | 0.953264 |
| MA0068.1 | 0.0216542 |
| MA0069.1 | 0.643292 |
| MA0070.1 | 0.634186 |
| MA0071.1 | 0.269487 |
| MA0072.1 | 0.626238 |
| MA0073.1 | 0.290179 |
| MA0074.1 | 0.318792 |
| MA0076.1 | 0.148159 |
| MA0077.1 | 0.605975 |
| MA0078.1 | 0.395048 |
| MA0081.1 | 0.193203 |
| MA0083.1 | 0.714187 |
| MA0084.1 | 1.27474 |
| MA0087.1 | 0.673355 |
| MA0088.1 | 0.292366 |
| MA0089.1 | 0 |
| MA0090.1 | 0.212772 |
| MA0091.1 | 0.24961 |
| MA0092.1 | 0.610874 |
| MA0093.1 | 0.130107 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.309116 |
| MA0101.1 | 0.538493 |
| MA0103.1 | 0.439015 |
| MA0105.1 | 0.341877 |
| MA0106.1 | 0.401864 |
| MA0107.1 | 0.428571 |
| MA0108.2 | 0.476838 |
| MA0109.1 | 0 |
| MA0111.1 | 0.223614 |
| MA0113.1 | 0.377232 |
| MA0114.1 | 0.291992 |
| MA0115.1 | 0.717599 |
| MA0116.1 | 0.117928 |
| MA0117.1 | 0.686999 |
| MA0119.1 | 0.183219 |
| MA0122.1 | 0.705806 |
| MA0124.1 | 0.901619 |
| MA0125.1 | 0.830088 |
| MA0130.1 | 0 |
| MA0131.1 | 1.14691 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.749615 |
| MA0136.1 | 0.335579 |
| MA0139.1 | 0.0558308 |
| MA0140.1 | 0.30902 |
| MA0141.1 | 0.155997 |
| MA0142.1 | 0.522654 |
| MA0143.1 | 0.391481 |
| MA0144.1 | 0.0881858 |
| MA0145.1 | 1.15108 |
| MA0146.1 | 0.56368 |
| MA0147.1 | 0.0952713 |
| MA0148.1 | 0.70223 |
| MA0149.1 | 0.18682 |
| MA0062.2 | 0.354916 |
| MA0035.2 | 0.312946 |
| MA0039.2 | 0.101713 |
| MA0138.2 | 0.445088 |
| MA0002.2 | 0.0572064 |
| MA0137.2 | 0.153989 |
| MA0104.2 | 0.0641853 |
| MA0047.2 | 0.357963 |
| MA0112.2 | 0.0599393 |
| MA0065.2 | 0.160972 |
| MA0150.1 | 0.227466 |
| MA0151.1 | 0 |
| MA0152.1 | 1.67957 |
| MA0153.1 | 0.765498 |
| MA0154.1 | 0.247047 |
| MA0155.1 | 0.0729675 |
| MA0156.1 | 0.885026 |
| MA0157.1 | 1.23539 |
| MA0158.1 | 0 |
| MA0159.1 | 0.101261 |
| MA0160.1 | 0.254455 |
| MA0161.1 | 0 |
| MA0162.1 | 0.903541 |
| MA0163.1 | 0.150434 |
| MA0164.1 | 0.335886 |
| MA0080.2 | 0.13897 |
| MA0018.2 | 0.344133 |
| MA0099.2 | 1.1194 |
| MA0079.2 | 0.0246716 |
| MA0102.2 | 1.32652 |
| MA0258.1 | 0.0789466 |
| MA0259.1 | 0.0890842 |
| MA0442.1 | 0 |
