MCL coexpression mm9:328
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0021801 | cerebral cortex radial glia guided migration | 0.0156138716923246 |
| GO:0021799 | cerebral cortex radially oriented cell migration | 0.0156138716923246 |
| GO:0021589 | cerebellum structural organization | 0.0156138716923246 |
| GO:0021813 | cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration | 0.0156138716923246 |
| GO:0021577 | hindbrain structural organization | 0.0156138716923246 |
| GO:0048532 | organization of an anatomical structure | 0.0156138716923246 |
| GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration | 0.0156138716923246 |
| GO:0021942 | radial glia guided migration of Purkinje cell | 0.0156138716923246 |
| GO:0021932 | hindbrain radial glia guided cell migration | 0.0249760353894974 |
| GO:0007168 | receptor guanylyl cyclase signaling pathway | 0.0249760353894974 |
| GO:0005516 | calmodulin binding | 0.0307942104658189 |
| GO:0021535 | cell migration in hindbrain | 0.0312123473389508 |
| GO:0021795 | cerebral cortex cell migration | 0.0384057263879851 |
| GO:0042169 | SH2 domain binding | 0.0415856935171347 |
| GO:0005083 | small GTPase regulator activity | 0.0415856935171347 |
| GO:0005954 | calcium- and calmodulin-dependent protein kinase complex | 0.0415856935171347 |
| GO:0021885 | forebrain cell migration | 0.0415856935171347 |
| GO:0022029 | telencephalon cell migration | 0.0415856935171347 |
| GO:0004274 | dipeptidyl-peptidase IV activity | 0.0459518053958278 |
| GO:0021987 | cerebral cortex development | 0.0498455976785651 |
| GO:0015629 | actin cytoskeleton | 0.0498455976785651 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| CNS neuron (sensu Vertebrata) | 4.05e-12 | 23 |
| neuroblast (sensu Vertebrata) | 4.05e-12 | 23 |
| neuron | 2.36e-07 | 33 |
| neuronal stem cell | 2.36e-07 | 33 |
| neuroblast | 2.36e-07 | 33 |
| electrically signaling cell | 2.36e-07 | 33 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.0493132 |
| MA0004.1 | 0.794862 |
| MA0006.1 | 0.0460466 |
| MA0007.1 | 0.118104 |
| MA0009.1 | 0.452863 |
| MA0014.1 | 0.043395 |
| MA0017.1 | 0.0561984 |
| MA0019.1 | 0.818593 |
| MA0024.1 | 0.415603 |
| MA0025.1 | 0.660968 |
| MA0027.1 | 2.04174 |
| MA0028.1 | 0.186822 |
| MA0029.1 | 0.397373 |
| MA0030.1 | 0.402861 |
| MA0031.1 | 0.373333 |
| MA0038.1 | 0.220281 |
| MA0040.1 | 0.463641 |
| MA0041.1 | 0.0860551 |
| MA0042.1 | 0.0797095 |
| MA0043.1 | 0.53743 |
| MA0046.1 | 0.483941 |
| MA0048.1 | 0.023533 |
| MA0050.1 | 0.149886 |
| MA0051.1 | 0.226644 |
| MA0052.1 | 0.47061 |
| MA0055.1 | 0.349671 |
| MA0056.1 | 0 |
| MA0057.1 | 0.430886 |
| MA0058.1 | 1.95905 |
| MA0059.1 | 2.64889 |
| MA0060.1 | 0.0217699 |
| MA0061.1 | 0.0296722 |
| MA0063.1 | 0 |
| MA0066.1 | 0.212546 |
| MA0067.1 | 0.764133 |
| MA0068.1 | 0.449127 |
| MA0069.1 | 0.470904 |
| MA0070.1 | 0.462521 |
| MA0071.1 | 0.149369 |
| MA0072.1 | 0.455219 |
| MA0073.1 | 3.23975 |
| MA0074.1 | 0.187944 |
| MA0076.1 | 0.229034 |
| MA0077.1 | 0.436665 |
| MA0078.1 | 0.250627 |
| MA0081.1 | 0.644573 |
| MA0083.1 | 0.536725 |
| MA0084.1 | 1.07765 |
| MA0087.1 | 0.4987 |
| MA0088.1 | 1.39052 |
| MA0089.1 | 0 |
| MA0090.1 | 0.348685 |
| MA0091.1 | 0.134352 |
| MA0092.1 | 0.107655 |
| MA0093.1 | 1.63531 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.180237 |
| MA0101.1 | 0.08669 |
| MA0103.1 | 0.218786 |
| MA0105.1 | 2.09451 |
| MA0106.1 | 0.256379 |
| MA0107.1 | 0.211319 |
| MA0108.2 | 0.320962 |
| MA0109.1 | 0 |
| MA0111.1 | 0.744051 |
| MA0113.1 | 0.664215 |
| MA0114.1 | 0.0290062 |
| MA0115.1 | 0.539917 |
| MA0116.1 | 0.0459718 |
| MA0117.1 | 0.511373 |
| MA0119.1 | 0.0869793 |
| MA0122.1 | 0.528896 |
| MA0124.1 | 0.714453 |
| MA0125.1 | 0.646095 |
| MA0130.1 | 0 |
| MA0131.1 | 0.299487 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.569948 |
| MA0136.1 | 0.583392 |
| MA0139.1 | 0.0699025 |
| MA0140.1 | 0.532112 |
| MA0141.1 | 0.0690765 |
| MA0142.1 | 0.361451 |
| MA0143.1 | 0.247626 |
| MA0144.1 | 0.0298861 |
| MA0145.1 | 0.034487 |
| MA0146.1 | 0.000260983 |
| MA0147.1 | 0.578585 |
| MA0148.1 | 0.136186 |
| MA0149.1 | 0.0894222 |
| MA0062.2 | 0.00879313 |
| MA0035.2 | 0.539678 |
| MA0039.2 | 0.145091 |
| MA0138.2 | 0.796689 |
| MA0002.2 | 0.91042 |
| MA0137.2 | 0.0677978 |
| MA0104.2 | 0.667344 |
| MA0047.2 | 0.219739 |
| MA0112.2 | 0.0857672 |
| MA0065.2 | 0.66648 |
| MA0150.1 | 0.756591 |
| MA0151.1 | 0 |
| MA0152.1 | 0.219814 |
| MA0153.1 | 0.584906 |
| MA0154.1 | 0.973726 |
| MA0155.1 | 0.354426 |
| MA0156.1 | 0.227959 |
| MA0157.1 | 0.335532 |
| MA0158.1 | 0 |
| MA0159.1 | 0.956625 |
| MA0160.1 | 0.137981 |
| MA0161.1 | 0 |
| MA0162.1 | 0.0935743 |
| MA0163.1 | 0.0779391 |
| MA0164.1 | 0.201705 |
| MA0080.2 | 0.806441 |
| MA0018.2 | 0.208409 |
| MA0099.2 | 0.288477 |
| MA0079.2 | 2.8347 |
| MA0102.2 | 1.12863 |
| MA0258.1 | 0.0253198 |
| MA0259.1 | 0.296386 |
| MA0442.1 | 0 |
