MCL coexpression mm9:1731
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr19:53526008..53526024,- | p2@5830416P10Rik |
| Mm9::chr7:109016961..109017012,- | p4@Folr1 |
| Mm9::chr7:109017023..109017036,- | p15@Folr1 |
| Mm9::chr7:109017526..109017537,- | p18@Folr1 |
| Mm9::chr7:109017548..109017587,- | p11@Folr1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0046655 | folic acid metabolic process | 0.00284884676491536 |
| GO:0006620 | posttranslational protein targeting to membrane | 0.00379846235322048 |
| GO:0008517 | folic acid transporter activity | 0.00379846235322048 |
| GO:0051183 | vitamin transporter activity | 0.00447675920200985 |
| GO:0051184 | cofactor transporter activity | 0.00447675920200985 |
| GO:0005542 | folic acid binding | 0.00447675920200985 |
| GO:0006760 | folic acid and derivative metabolic process | 0.00447675920200985 |
| GO:0042558 | pteridine and derivative metabolic process | 0.00462937599298745 |
| GO:0045047 | protein targeting to ER | 0.00601423205926575 |
| GO:0006612 | protein targeting to membrane | 0.00769188626527147 |
| GO:0006767 | water-soluble vitamin metabolic process | 0.0101004567119726 |
| GO:0006752 | group transfer coenzyme metabolic process | 0.0128198104421191 |
| GO:0006766 | vitamin metabolic process | 0.0134302776060295 |
| GO:0046483 | heterocycle metabolic process | 0.0134302776060295 |
| GO:0019842 | vitamin binding | 0.0197743481329419 |
| GO:0006725 | aromatic compound metabolic process | 0.0197743481329419 |
| GO:0048503 | GPI anchor binding | 0.0197743481329419 |
| GO:0006732 | coenzyme metabolic process | 0.0242721744370788 |
| GO:0035091 | phosphoinositide binding | 0.0242721744370788 |
| GO:0045045 | secretory pathway | 0.0242721744370788 |
| GO:0051186 | cofactor metabolic process | 0.0242721744370788 |
| GO:0006605 | protein targeting | 0.0242721744370788 |
| GO:0005543 | phospholipid binding | 0.0242721744370788 |
| GO:0032940 | secretion by cell | 0.0242721744370788 |
| GO:0032787 | monocarboxylic acid metabolic process | 0.0242721744370788 |
| GO:0046903 | secretion | 0.0283788966197337 |
| GO:0008289 | lipid binding | 0.0375625721596247 |
| GO:0006886 | intracellular protein transport | 0.0391716430175862 |
| GO:0005624 | membrane fraction | 0.0411704306671639 |
| GO:0019752 | carboxylic acid metabolic process | 0.0411704306671639 |
| GO:0006082 | organic acid metabolic process | 0.0411704306671639 |
| GO:0000267 | cell fraction | 0.044157124856188 |
| GO:0046907 | intracellular transport | 0.0490346958324825 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| oligodendrocyte precursor cell | 3.37e-08 | 8 |
| Ontology term | p-value | n |
|---|---|---|
| reproductive structure | 1.69e-09 | 26 |
| reproductive system | 1.69e-09 | 26 |
| reproductive organ | 2.16e-09 | 24 |
| urinary system structure | 1.39e-08 | 18 |
| gonad | 3.40e-08 | 18 |
| gonad primordium | 3.40e-08 | 18 |
| renal system | 5.84e-08 | 19 |
| kidney | 9.06e-08 | 14 |
| kidney mesenchyme | 9.06e-08 | 14 |
| upper urinary tract | 9.06e-08 | 14 |
| kidney rudiment | 9.06e-08 | 14 |
| kidney field | 9.06e-08 | 14 |
| compound organ | 1.38e-07 | 43 |
| external genitalia | 1.77e-07 | 17 |
| indifferent external genitalia | 1.77e-07 | 17 |
| indifferent gonad | 1.77e-07 | 17 |
| testis | 8.64e-07 | 14 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.0833043 |
| MA0004.1 | 0.603793 |
| MA0006.1 | 0.419915 |
| MA0007.1 | 0.587678 |
| MA0009.1 | 1.06266 |
| MA0014.1 | 0.0502051 |
| MA0017.1 | 2.9605 |
| MA0019.1 | 0.874061 |
| MA0024.1 | 2.32185 |
| MA0025.1 | 1.30092 |
| MA0027.1 | 2.72141 |
| MA0028.1 | 0.43138 |
| MA0029.1 | 0.995171 |
| MA0030.1 | 1.00195 |
| MA0031.1 | 0.965177 |
| MA0038.1 | 0.757669 |
| MA0040.1 | 1.07552 |
| MA0041.1 | 0.522007 |
| MA0042.1 | 0.507715 |
| MA0043.1 | 1.1618 |
| MA0046.1 | 1.09955 |
| MA0048.1 | 0.205696 |
| MA0050.1 | 0.645342 |
| MA0051.1 | 0.767098 |
| MA0052.1 | 1.08379 |
| MA0055.1 | 0.0851423 |
| MA0056.1 | 0 |
| MA0057.1 | 1.06992 |
| MA0058.1 | 0.50032 |
| MA0059.1 | 0.513699 |
| MA0060.1 | 0.330907 |
| MA0061.1 | 0.955135 |
| MA0063.1 | 0 |
| MA0066.1 | 0.746072 |
| MA0067.1 | 1.41352 |
| MA0068.1 | 1.08757 |
| MA0069.1 | 1.08414 |
| MA0070.1 | 1.07418 |
| MA0071.1 | 0.644448 |
| MA0072.1 | 1.06547 |
| MA0073.1 | 0.00450236 |
| MA0074.1 | 0.708108 |
| MA0076.1 | 0.470037 |
| MA0077.1 | 1.04318 |
| MA0078.1 | 0.801834 |
| MA0081.1 | 0.53877 |
| MA0083.1 | 1.16099 |
| MA0084.1 | 1.74401 |
| MA0087.1 | 1.11687 |
| MA0088.1 | 0.453686 |
| MA0089.1 | 0 |
| MA0090.1 | 1.39153 |
| MA0091.1 | 0.617887 |
| MA0092.1 | 0.567278 |
| MA0093.1 | 0.440484 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.695835 |
| MA0101.1 | 0.523409 |
| MA0103.1 | 0.460936 |
| MA0105.1 | 0.248108 |
| MA0106.1 | 0.809991 |
| MA0107.1 | 0.454197 |
| MA0108.2 | 0.897859 |
| MA0109.1 | 0 |
| MA0111.1 | 0.582193 |
| MA0113.1 | 0.780358 |
| MA0114.1 | 1.69206 |
| MA0115.1 | 1.16466 |
| MA0116.1 | 1.07655 |
| MA0117.1 | 1.13165 |
| MA0119.1 | 1.30068 |
| MA0122.1 | 1.15196 |
| MA0124.1 | 1.35963 |
| MA0125.1 | 1.28445 |
| MA0130.1 | 0 |
| MA0131.1 | 0.869325 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.19898 |
| MA0136.1 | 0.729175 |
| MA0139.1 | 0.295945 |
| MA0140.1 | 0.695713 |
| MA0141.1 | 1.21195 |
| MA0142.1 | 0.950155 |
| MA0143.1 | 0.797553 |
| MA0144.1 | 0.365053 |
| MA0145.1 | 0.927481 |
| MA0146.1 | 0.822925 |
| MA0147.1 | 0.378658 |
| MA0148.1 | 0.621195 |
| MA0149.1 | 0.529387 |
| MA0062.2 | 0.254018 |
| MA0035.2 | 0.700704 |
| MA0039.2 | 0.140205 |
| MA0138.2 | 0.861035 |
| MA0002.2 | 0.299191 |
| MA0137.2 | 0.479301 |
| MA0104.2 | 0.315156 |
| MA0047.2 | 0.75686 |
| MA0112.2 | 0.157681 |
| MA0065.2 | 0.929207 |
| MA0150.1 | 0.587557 |
| MA0151.1 | 0 |
| MA0152.1 | 0.756973 |
| MA0153.1 | 1.21594 |
| MA0154.1 | 0.203217 |
| MA0155.1 | 0.515751 |
| MA0156.1 | 1.18326 |
| MA0157.1 | 0.91689 |
| MA0158.1 | 0 |
| MA0159.1 | 0.389847 |
| MA0160.1 | 0.624415 |
| MA0161.1 | 0 |
| MA0162.1 | 0.0699535 |
| MA0163.1 | 0.0644585 |
| MA0164.1 | 1.7313 |
| MA0080.2 | 0.455167 |
| MA0018.2 | 0.739807 |
| MA0099.2 | 0.854449 |
| MA0079.2 | 0.0381166 |
| MA0102.2 | 1.79669 |
| MA0258.1 | 0.346619 |
| MA0259.1 | 0.366802 |
| MA0442.1 | 0 |
