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Coexpression cluster:C1297

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Full id: C1297_trachea_salivary_seminal_ductus_eye_submaxillary_throat



Phase1 CAGE Peaks

Hg19::chr10:115511386..115511397,+p4@C10orf81
Hg19::chr10:115511412..115511428,+p3@C10orf81
Hg19::chr10:115511434..115511454,+p1@C10orf81
Hg19::chr11:34909948..34909959,-p@chr11:34909948..34909959
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Hg19::chr13:24144796..24144809,+p6@TNFRSF19
Hg19::chr3:46506387..46506404,-p1@LTF


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005031tumor necrosis factor receptor activity0.0166781938844186
GO:0043120tumor necrosis factor binding0.0166781938844186
GO:0005035death receptor activity0.0166781938844186
GO:0008199ferric iron binding0.0374900304819804
GO:0055072iron ion homeostasis0.0374900304819804
GO:0006879cellular iron ion homeostasis0.0374900304819804
GO:0006826iron ion transport0.0374900304819804
GO:0007254JNK cascade0.0374900304819804
GO:0031098stress-activated protein kinase signaling pathway0.0374900304819804
GO:0006959humoral immune response0.0374900304819804
GO:0042742defense response to bacterium0.037829791018342
GO:0019955cytokine binding0.037829791018342
GO:0000041transition metal ion transport0.037829791018342
GO:0009617response to bacterium0.037829791018342
GO:0000165MAPKKK cascade0.0475310480760905
GO:0030005cellular di-, tri-valent inorganic cation homeostasis0.0475310480760905
GO:0055066di-, tri-valent inorganic cation homeostasis0.0475310480760905
GO:0030003cellular cation homeostasis0.0475310480760905
GO:0055080cation homeostasis0.0475310480760905
GO:0051707response to other organism0.0475310480760905
GO:0006917induction of apoptosis0.0475310480760905
GO:0012502induction of programmed cell death0.0475310480760905
GO:0055082cellular chemical homeostasis0.0475310480760905
GO:0006873cellular ion homeostasis0.0475310480760905
GO:0015674di-, tri-valent inorganic cation transport0.0475310480760905
GO:0043065positive regulation of apoptosis0.0475310480760905
GO:0043068positive regulation of programmed cell death0.0475310480760905
GO:0050801ion homeostasis0.0475310480760905
GO:0009607response to biotic stimulus0.0496572657893629



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.321379
MA0004.10.558729
MA0006.10.391183
MA0007.10.539222
MA0009.11.03681
MA0014.10.262822
MA0017.10.432438
MA0019.10.7124
MA0024.10.929647
MA0025.11.17262
MA0027.12.65688
MA0028.10.408079
MA0029.10.949428
MA0030.10.937696
MA0031.10.871496
MA0038.10.665566
MA0040.10.955415
MA0041.10.578072
MA0042.10.544748
MA0043.11.03713
MA0046.11.02569
MA0048.10.464411
MA0050.12.3112
MA0051.12.6843
MA0052.10.959373
MA0055.10.465994
MA0056.10
MA0057.10.147053
MA0058.10.458909
MA0059.10.457555
MA0060.10.267412
MA0061.10.671725
MA0063.10
MA0066.10.66601
MA0067.11.35893
MA0068.11.09642
MA0069.11.02175
MA0070.11.01032
MA0071.10.625297
MA0072.11.00572
MA0073.10.00563817
MA0074.10.660398
MA0076.10.475586
MA0077.10.997832
MA0078.10.763954
MA0081.10.457725
MA0083.11.04447
MA0084.11.5477
MA0087.11.00322
MA0088.10.0971959
MA0089.10
MA0090.10.490736
MA0091.10.561458
MA0092.11.29635
MA0093.10.394379
MA0095.10
MA0098.10
MA0100.11.62836
MA0101.11.02896
MA0103.10.381434
MA0105.10.134725
MA0106.10.70837
MA0107.10.857383
MA0108.20.868347
MA0109.10
MA0111.10.504913
MA0113.10.725375
MA0114.10.845337
MA0115.11.28169
MA0116.10.323925
MA0117.11.07516
MA0119.10.440684
MA0122.11.10154
MA0124.11.23968
MA0125.11.15445
MA0130.10
MA0131.10.782708
MA0132.10
MA0133.10
MA0135.11.06778
MA0136.11.61362
MA0139.10.226048
MA0140.10.622527
MA0141.10.455728
MA0142.10.838805
MA0143.10.725558
MA0144.11.47313
MA0145.10.107156
MA0146.10.0213085
MA0147.10.327615
MA0148.12.43826
MA0149.10.612449
MA0062.20.658749
MA0035.20.621793
MA0039.20.0313803
MA0138.20.765223
MA0002.21.3092
MA0137.20.414885
MA0104.20.26661
MA0047.20.695777
MA0112.20.680553
MA0065.20.109623
MA0150.10.484557
MA0151.10
MA0152.10.629368
MA0153.11.13732
MA0154.11.3291
MA0155.10.318517
MA0156.11.88357
MA0157.10.810597
MA0158.10
MA0159.10.328286
MA0160.10.600559
MA0161.10
MA0162.10.0383129
MA0163.10.0270301
MA0164.10.738243
MA0080.21.80563
MA0018.20.709805
MA0099.20.629739
MA0079.20.00183606
MA0102.21.58513
MA0258.10.289793
MA0259.10.336472
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
TFAP2C#702235.404614304930110.01277576166695870.046055979176953



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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