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UBERON:0001044

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Name:salivary gland
Definition:"saliva-secreting exocrine glands of the oral cavity[GO]. The salivary glands in mammals are exocrine glands, glands with ducts, that produce saliva. They also secrete amylase, an enzyme that breaks down starch into maltose. In other organisms such as insects, salivary glands are often used to produce biologically important proteins like silk or glues, and fly salivary glands contain polytene chromosomes that have been useful in genetic research[WP]." [GO:0007431, Wikipedia:Salivary_gland]
Xrefs:
links:

BTO:0001203
EFO:0000859
EHDAA:7987
EHDAA2:0001775
EMAPA:17751
EV:0100059
FBbt:00005382
FMA:9597
GAID:937
galen:SalivaryGland
[1]
MA:0000346
MAT:0000079
MESH:A.10.336.779
MIAA:0000079
ncithesaurus:Salivary_Gland
OpenCyc:Mx4rvVjl5ZwpEbGdrcN5Y29ycA
SCTID:181236000

VHOG:0000376
Comments:currently we define saliva and salivary glands very generally in functional terms but it may be more appropriate to split this class. From WP: In most vertebrates, saliva does not contain any enzymes, consisting of mucus and water only, and its primary function is to moisten food while eating. As a result, true salivary glands are rarely found in fish or aquatic tetrapods, although there are often individual mucus-secreting cells. Amphibians have a single salivary gland, the intermaxillary gland, located in the forward part of the palate. Reptiles and birds normally have only very small glands on the lips, palate, and base of the mouth, although there are some birds with large glands, which produce a sticky saliva that helps in nest-building. The distinct parotid, submandibular, and sublingual glands are only developed in mammals.[3] The salivary glands of some species, however, are modified to produce enzymes; salivary amylase is found in many, but by no means all, bird and mammal species (including humans, as noted above). Furthermore, the venom glands of poisonous snakes, Gila monsters, and some shrews, are modified salivary glands
Alt_id: UBERON:FBbt_00005382-FMA_9597-MA_0000346-MIAA_0000079
Subset: functional_classification
organ_slim
uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0000078(mixed ectoderm/mesoderm/endoderm-derived structure),UBERON:0003293(gland of oral region),UBERON:0003294(gland of foregut),UBERON:0010047(oral gland)
part_of:UBERON:0000166(oral opening),UBERON:0000167(oral cavity),UBERON:0001041(foregut)



Children

is a:UBERON:0001829 (major salivary gland),UBERON:0012102 (buccal salivary gland)
derives from:FF:0010093 (human salivary gland - adult sample)
part of:CL:0002623 (acinar cell of salivary gland),UBERON:0004809 (salivary gland epithelium),UBERON:0006298 (submandibular gland primordium),CL:1001596 (salivary gland glandular cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001044 (salivary gland), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.83e-98FFCP PHASE2:Hg19::chr4:94247088..94247093,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:94247088..94247093, -
1.83e-98FFCP PHASE1:Hg19::chr6:99243504..99243506,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr6:99243504..99243506, +
1.83e-98FFCP PHASE2:Hg19::chr1:9009469..9009476,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr1:9009469..9009476, +
1.83e-98FFCP PHASE1:Hg19::chrX:53171146..53171174,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chrX:53171146..53171174, -
1.83e-98FFCP PHASE2:Hg19::chr20:31763221..31763230,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31763221..31763230, +
1.83e-98FFCP PHASE2:Hg19::chr4:33651567..33651572,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:33651567..33651572, -
1.83e-98FFCP PHASE2:Hg19::chr4:71255816..71255827,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:71255816..71255827, -
1.83e-98FFCP PHASE2:Hg19::chr1:9009322..9009333,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr1:9009322..9009333, +
1.83e-98FFCP PHASE2:Hg19::chr4:70894345..70894354,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70894345..70894354, +
1.83e-98FFCP PHASE1:Hg19::chr4:70924295..70924307,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70924295..70924307, +
1.83e-98FFCP PHASE2:Hg19::chr20:31760756..31760778,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31760756..31760778, +
1.83e-98FFCP PHASE1:Hg19::chr20:31763318..31763328,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31763318..31763328, -
1.83e-98FFCP PHASE2:Hg19::chr12:68527632..68527634,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr12:68527632..68527634, +
1.83e-98FFCP PHASE2:Hg19::chr4:71028660..71028668,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:71028660..71028668, +
1.83e-98FFCP PHASE1:Hg19::chr17:66624238..66624249,+#_8dfd5d05f9728abfbec2a4a02418ea73p1@AL117652
1.83e-98FFCP PHASE1:Hg19::chr12:11035201..11035242,-#_8dfd5d05f9728abfbec2a4a02418ea73p6@PRR4
1.83e-98FFCP PHASE2:Hg19::chr3:10569527..10569554,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr3:10569527..10569554, -
1.83e-98FFCP PHASE2:Hg19::chr12:11037049..11037056,-#_8dfd5d05f9728abfbec2a4a02418ea73p5@PRH1
1.83e-98FFCP PHASE1:Hg19::chrX:129565220..129565223,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chrX:129565220..129565223, +
1.83e-98FFCP PHASE2:Hg19::chr6:99243504..99243506,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr6:99243504..99243506, +
1.83e-98FFCP PHASE1:Hg19::chr20:31761883..31761894,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31761883..31761894, +
1.83e-98FFCP PHASE2:Hg19::chrX:53171146..53171174,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chrX:53171146..53171174, -
1.83e-98FFCP PHASE1:Hg19::chr4:71029698..71029719,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:71029698..71029719, +
1.83e-98FFCP PHASE2:Hg19::chr4:70859008..70859019,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70859008..70859019, +
1.83e-98FFCP PHASE1:Hg19::chr1:9009400..9009412,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr1:9009400..9009412, +
1.83e-98FFCP PHASE1:Hg19::chr4:70868036..70868047,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70868036..70868047, +
1.83e-98FFCP PHASE1:Hg19::chr7:109641728..109641729,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr7:109641728..109641729, -
1.83e-98FFCP PHASE1:Hg19::chr20:31756995..31757006,+#_8dfd5d05f9728abfbec2a4a02418ea73p5@BPIFA2
1.83e-98FFCP PHASE2:Hg19::chr12:55224312..55224339,+#_8dfd5d05f9728abfbec2a4a02418ea73p6@MUCL1
1.83e-98FFCP PHASE2:Hg19::chr4:70924295..70924307,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70924295..70924307, +
1.83e-98FFCP PHASE1:Hg19::chr4:71024386..71024397,+#_8dfd5d05f9728abfbec2a4a02418ea73p8@C4orf40
1.83e-98FFCP PHASE2:Hg19::chr20:31763318..31763328,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31763318..31763328, -
1.83e-98FFCP PHASE2:Hg19::chr17:66624238..66624249,+#_8dfd5d05f9728abfbec2a4a02418ea73p1@AL117652
1.83e-98FFCP PHASE2:Hg19::chr12:11033611..11033616,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr12:11033611..11033616, +
1.83e-98FFCP PHASE1:Hg19::chr6:25004699..25004706,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr6:25004699..25004706, -
1.83e-98FFCP PHASE1:Hg19::chr5:52450586..52450589,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr5:52450586..52450589, -
1.83e-98FFCP PHASE2:Hg19::chr1:9009400..9009412,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr1:9009400..9009412, +
1.83e-98FFCP PHASE2:Hg19::chrX:129565220..129565223,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chrX:129565220..129565223, +
1.83e-98FFCP PHASE2:Hg19::chr20:31761883..31761894,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31761883..31761894, +
1.83e-98FFCP PHASE1:Hg19::chr20:31768317..31768326,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31768317..31768326, +
1.83e-98FFCP PHASE2:Hg19::chr4:71029698..71029719,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:71029698..71029719, +
1.83e-98FFCP PHASE1:Hg19::chr12:11037034..11037039,-#_8dfd5d05f9728abfbec2a4a02418ea73p4@PRH1
1.83e-98FFCP PHASE1:Hg19::chr15:91304387..91304431,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr15:91304387..91304431, +
1.83e-98FFCP PHASE1:Hg19::chr12:55224189..55224198,+#_8dfd5d05f9728abfbec2a4a02418ea73p9@MUCL1
1.83e-98FFCP PHASE2:Hg19::chr12:11083291..11083303,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr12:11083291..11083303, -
1.83e-98FFCP PHASE2:Hg19::chr6:25004699..25004706,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr6:25004699..25004706, -
1.83e-98FFCP PHASE2:Hg19::chr5:52450586..52450589,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr5:52450586..52450589, -
1.83e-98FFCP PHASE2:Hg19::chr4:70868036..70868047,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70868036..70868047, +
1.83e-98FFCP PHASE1:Hg19::chr4:70916611..70916657,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70916611..70916657, +
1.83e-98FFCP PHASE2:Hg19::chr11:17925808..17925814,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr11:17925808..17925814, -
1.83e-98FFCP PHASE2:Hg19::chr7:109641728..109641729,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr7:109641728..109641729, -
1.83e-98FFCP PHASE2:Hg19::chr20:31756995..31757006,+#_8dfd5d05f9728abfbec2a4a02418ea73p5@BPIFA2
1.83e-98FFCP PHASE1:Hg19::chr20:31763234..31763252,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31763234..31763252, +
1.83e-98FFCP PHASE1:Hg19::chr13:21383303..21383305,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr13:21383303..21383305, +
1.83e-98FFCP PHASE2:Hg19::chr4:71024386..71024397,+#_8dfd5d05f9728abfbec2a4a02418ea73p8@C4orf40
1.83e-98FFCP PHASE1:Hg19::chr12:11033561..11033572,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr12:11033561..11033572, +
1.83e-98FFCP PHASE1:Hg19::chr4:70859008..70859019,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70859008..70859019, +
1.83e-98FFCP PHASE1:Hg19::chr4:70896475..70896477,+#_8dfd5d05f9728abfbec2a4a02418ea73p2@HTN3
1.83e-98FFCP PHASE1:Hg19::chr14:49942109..49942118,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr14:49942109..49942118, -
1.83e-98FFCP PHASE1:Hg19::chr20:31760791..31760799,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31760791..31760799, +
1.83e-98FFCP PHASE1:Hg19::chr4:71028882..71028890,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:71028882..71028890, +
1.83e-98FFCP PHASE2:Hg19::chr20:31768317..31768326,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31768317..31768326, +
1.83e-98FFCP PHASE1:Hg19::chr4:71255868..71255873,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:71255868..71255873, +
1.83e-98FFCP PHASE1:Hg19::chr20:23858235..23858249,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:23858235..23858249, -
1.83e-98FFCP PHASE1:Hg19::chr1:9009335..9009343,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr1:9009335..9009343, +
1.83e-98FFCP PHASE1:Hg19::chr20:31755975..31755986,+#_8dfd5d05f9728abfbec2a4a02418ea73p2@BPIFA2
1.83e-98FFCP PHASE1:Hg19::chr16:83959468..83959471,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr16:83959468..83959471, +
1.83e-98FFCP PHASE2:Hg19::chr4:70916611..70916657,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70916611..70916657, +
1.83e-98FFCP PHASE1:Hg19::chr1:41448820..41448825,+#_8dfd5d05f9728abfbec2a4a02418ea73p13@CTPS
1.83e-98FFCP PHASE2:Hg19::chr20:31763234..31763252,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31763234..31763252, +
1.83e-98FFCP PHASE1:Hg19::chr5:36237795..36237799,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr5:36237795..36237799, -
1.83e-98FFCP PHASE2:Hg19::chr4:71255868..71255873,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:71255868..71255873, +
1.83e-98FFCP PHASE2:Hg19::chr20:23858235..23858249,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:23858235..23858249, -
1.83e-98FFCP PHASE2:Hg19::chr1:9009335..9009343,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr1:9009335..9009343, +
1.83e-98FFCP PHASE1:Hg19::chr1:9022642..9022656,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr1:9022642..9022656, +
1.83e-98FFCP PHASE1:Hg19::chr10:12466842..12466843,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr10:12466842..12466843, +
1.83e-98FFCP PHASE2:Hg19::chr4:70896475..70896477,+#_8dfd5d05f9728abfbec2a4a02418ea73p2@HTN3
1.83e-98FFCP PHASE1:Hg19::chr4:70924317..70924327,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70924317..70924327, +
1.83e-98FFCP PHASE2:Hg19::chr14:49942089..49942094,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr14:49942089..49942094, -
1.83e-98FFCP PHASE1:Hg19::chr14:69012249..69012259,+#_8dfd5d05f9728abfbec2a4a02418ea73p19@RAD51B
1.83e-98FFCP PHASE2:Hg19::chr20:31760791..31760799,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31760791..31760799, +
1.83e-98FFCP PHASE2:Hg19::chr4:71028882..71028890,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:71028882..71028890, +
1.83e-98FFCP PHASE1:Hg19::chr4:71232526..71232531,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:71232526..71232531, +
1.83e-98FFCP PHASE1:Hg19::chr17:66624280..66624292,+#_8dfd5d05f9728abfbec2a4a02418ea73p3@AL117652
1.83e-98FFCP PHASE2:Hg19::chr14:21489085..21489115,-#_8dfd5d05f9728abfbec2a4a02418ea73p62@NDRG2
1.83e-98FFCP PHASE1:Hg19::chr14:21516851..21516857,-#_8dfd5d05f9728abfbec2a4a02418ea73p63@NDRG2
1.83e-98FFCP PHASE1:Hg19::chr12:11035682..11035705,-#_8dfd5d05f9728abfbec2a4a02418ea73p4@PRR4
1.83e-98FFCP PHASE2:Hg19::chr5:36237795..36237799,-#_8dfd5d05f9728abfbec2a4a02418ea73p@chr5:36237795..36237799, -
1.83e-98FFCP PHASE1:Hg19::chr4:70902060..70902081,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70902060..70902081, +
1.83e-98FFCP PHASE2:Hg19::chr20:31755975..31755986,+#_8dfd5d05f9728abfbec2a4a02418ea73p2@BPIFA2
1.83e-98FFCP PHASE1:Hg19::chr20:31761911..31761920,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr20:31761911..31761920, +
1.83e-98FFCP PHASE2:Hg19::chr16:83959468..83959471,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr16:83959468..83959471, +
1.83e-98FFCP PHASE2:Hg19::chr1:41448820..41448825,+#_8dfd5d05f9728abfbec2a4a02418ea73p13@CTPS
1.83e-98FFCP PHASE1:Hg19::chr1:9009415..9009422,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr1:9009415..9009422, +
1.83e-98FFCP PHASE1:Hg19::chr4:70868063..70868067,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70868063..70868067, +
1.83e-98FFCP PHASE2:Hg19::chr1:9022642..9022656,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr1:9022642..9022656, +
1.83e-98FFCP PHASE2:Hg19::chr4:70924317..70924327,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:70924317..70924327, +
1.83e-98FFCP PHASE1:Hg19::chr4:71028409..71028415,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:71028409..71028415, +
1.83e-98FFCP PHASE2:Hg19::chr4:71232526..71232531,+#_8dfd5d05f9728abfbec2a4a02418ea73p@chr4:71232526..71232531, +
1.83e-98FFCP PHASE2:Hg19::chr17:66624280..66624292,+#_8dfd5d05f9728abfbec2a4a02418ea73p3@AL117652

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