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Coexpression cluster:C1564

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Full id: C1564_heart_spinal_left_locus_cerebellum_brain_breast



Phase1 CAGE Peaks

Hg19::chr10:116527977..116528075,-p3@ABLIM1
Hg19::chr10:116528079..116528090,-p17@ABLIM1
Hg19::chr10:116528118..116528130,-p12@ABLIM1
Hg19::chr10:116528142..116528153,-p16@ABLIM1
Hg19::chr10:116528240..116528280,-p11@ABLIM1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.16e-58114
neural tube1.13e-5056
neural rod1.13e-5056
future spinal cord1.13e-5056
neural keel1.13e-5056
regional part of nervous system5.10e-4753
regional part of brain5.10e-4753
central nervous system5.51e-4581
neural plate1.43e-4082
presumptive neural plate1.43e-4082
nervous system1.37e-3989
brain8.31e-3968
future brain8.31e-3968
neurectoderm1.26e-3786
regional part of forebrain1.86e-3641
forebrain1.86e-3641
anterior neural tube1.86e-3641
future forebrain1.86e-3641
telencephalon1.96e-3234
brain grey matter2.29e-3234
gray matter2.29e-3234
cerebral hemisphere3.26e-3032
regional part of telencephalon4.86e-3032
ecto-epithelium2.59e-29104
structure with developmental contribution from neural crest7.46e-28132
pre-chordal neural plate5.56e-2761
regional part of cerebral cortex6.11e-2722
neocortex1.36e-2420
cerebral cortex9.57e-2325
pallium9.57e-2325
anatomical cluster8.06e-22373
organ system subdivision1.23e-21223
ectoderm-derived structure4.72e-21171
ectoderm4.72e-21171
presumptive ectoderm4.72e-21171
anatomical conduit1.30e-17240
tube9.58e-17192
posterior neural tube6.61e-1515
chordal neural plate6.61e-1515
multi-tissue structure5.04e-14342
segmental subdivision of hindbrain1.74e-1112
hindbrain1.74e-1112
presumptive hindbrain1.74e-1112
basal ganglion3.30e-119
nuclear complex of neuraxis3.30e-119
aggregate regional part of brain3.30e-119
collection of basal ganglia3.30e-119
cerebral subcortex3.30e-119
neural nucleus4.23e-119
nucleus of brain4.23e-119
epithelium5.41e-11306
cell layer1.25e-10309
organ part1.67e-10218
segmental subdivision of nervous system2.50e-1013
temporal lobe2.71e-096
telencephalic nucleus8.20e-097
brainstem1.55e-086
organ2.37e-08503
gyrus3.02e-086
regional part of metencephalon4.28e-089
metencephalon4.28e-089
future metencephalon4.28e-089
anatomical system8.00e-08624
multi-cellular organism8.12e-08656
anatomical group9.59e-08625
limbic system1.79e-075
developing anatomical structure2.84e-07581
occipital lobe2.91e-075
embryo4.02e-07592
parietal lobe6.51e-075


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.