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Coexpression cluster:C1470

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Full id: C1470_acute_Renal_clear_Endothelial_diaphragm_skeletal_Lymphatic



Phase1 CAGE Peaks

Hg19::chr1:208060723..208060734,-p@chr1:208060723..208060734
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Hg19::chr1:208060913..208060939,-p@chr1:208060913..208060939
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Hg19::chr1:208084373..208084384,-p7@CD34
Hg19::chr1:208084387..208084511,-p1@CD34
Hg19::chr1:208084527..208084543,-p5@CD34
Hg19::chr1:208084585..208084627,-p3@CD34


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism9.87e-45114
anatomical conduit1.12e-15240
neural tube8.44e-1556
neural rod8.44e-1556
future spinal cord8.44e-1556
neural keel8.44e-1556
anatomical cluster3.78e-14373
regional part of nervous system3.98e-1453
regional part of brain3.98e-1453
regional part of forebrain3.25e-1341
forebrain3.25e-1341
anterior neural tube3.25e-1341
future forebrain3.25e-1341
tube4.41e-13192
telencephalon8.07e-1234
brain grey matter8.65e-1234
gray matter8.65e-1234
neural plate4.77e-1182
presumptive neural plate4.77e-1182
cerebral hemisphere8.47e-1132
regional part of telencephalon9.29e-1132
cerebral cortex2.00e-1025
pallium2.00e-1025
neurectoderm5.32e-1086
central nervous system1.75e-0981
brain2.53e-0968
future brain2.53e-0968
structure with developmental contribution from neural crest3.36e-09132
vessel1.47e-0868
regional part of cerebral cortex2.96e-0822
pre-chordal neural plate3.60e-0861
nervous system4.98e-0889
blood vessel endothelium8.66e-0818
endothelium8.66e-0818
cardiovascular system endothelium8.66e-0818
organ part3.96e-07218
neocortex4.01e-0720
ecto-epithelium4.75e-07104
splanchnic layer of lateral plate mesoderm5.67e-0783
vasculature7.91e-0778
vascular system7.91e-0778
lymphoid system8.38e-0710


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.