MCL coexpression mm9:809

Phase1 CAGE Peaks

	Short description
Mm9::chr12:70260096..70260120,-	p1@Gm10059 p1@Gm14303 p1@Gm2581 p1@Rps29
Mm9::chr17:26260459..26260499,+	p1@Mrpl28
Mm9::chr17:46247931..46247971,+	p1@Mrps18a
Mm9::chr19:10278691..10278727,+	p1@1810006K21Rik
Mm9::chr3:96001503..96001557,-	p1@Bola1
Mm9::chr4:155177709..155177749,+	p1@Mrpl20
Mm9::chr5:136592548..136592610,+	p1@Polr2j
Mm9::chr5:23349903..23349969,-	p1@Tomm7
Mm9::chr9:61762345..61762381,-	p1@Gm11942 p1@Gm13777 p1@Rplp1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0030529	ribonucleoprotein complex	0.000977227371540093
GO:0003735	structural constituent of ribosome	0.000977227371540093
GO:0005840	ribosome	0.000977227371540093
GO:0005739	mitochondrion	0.00511310553386146
GO:0033279	ribosomal subunit	0.00511310553386146
GO:0032991	macromolecular complex	0.00511310553386146
GO:0006412	translation	0.00723930261923568
GO:0005666	DNA-directed RNA polymerase III complex	0.0117906437470871
GO:0009059	macromolecule biosynthetic process	0.0184646870897222
GO:0044444	cytoplasmic part	0.02519769300812
GO:0044249	cellular biosynthetic process	0.033176034383354
GO:0000428	DNA-directed RNA polymerase complex	0.0357435504572228
GO:0055029	nuclear DNA-directed RNA polymerase complex	0.0357435504572228
GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	0.0357435504572228
GO:0022884	macromolecule transmembrane transporter activity	0.0357435504572228
GO:0030880	RNA polymerase complex	0.0357435504572228
GO:0005843	cytosolic small ribosomal subunit (sensu Eukaryota)	0.0357435504572228
GO:0044429	mitochondrial part	0.0357435504572228
GO:0044446	intracellular organelle part	0.0357435504572228
GO:0044422	organelle part	0.0357435504572228
GO:0000315	organellar large ribosomal subunit	0.0357435504572228
GO:0005762	mitochondrial large ribosomal subunit	0.0357435504572228
GO:0009058	biosynthetic process	0.0357435504572228
GO:0005741	mitochondrial outer membrane	0.0357435504572228
GO:0008320	protein transmembrane transporter activity	0.0357435504572228
GO:0031968	organelle outer membrane	0.0397758379675364
GO:0019843	rRNA binding	0.0400371094597319
GO:0010467	gene expression	0.0473908350928618
GO:0015935	small ribosomal subunit	0.0485648897514198

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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