MCL coexpression mm9:809
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr12:70260096..70260120,- | p1@Gm10059 p1@Gm14303 p1@Gm2581 p1@Rps29 |
| Mm9::chr17:26260459..26260499,+ | p1@Mrpl28 |
| Mm9::chr17:46247931..46247971,+ | p1@Mrps18a |
| Mm9::chr19:10278691..10278727,+ | p1@1810006K21Rik |
| Mm9::chr3:96001503..96001557,- | p1@Bola1 |
| Mm9::chr4:155177709..155177749,+ | p1@Mrpl20 |
| Mm9::chr5:136592548..136592610,+ | p1@Polr2j |
| Mm9::chr5:23349903..23349969,- | p1@Tomm7 |
| Mm9::chr9:61762345..61762381,- | p1@Gm11942 p1@Gm13777 p1@Rplp1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0030529 | ribonucleoprotein complex | 0.000977227371540093 |
| GO:0003735 | structural constituent of ribosome | 0.000977227371540093 |
| GO:0005840 | ribosome | 0.000977227371540093 |
| GO:0005739 | mitochondrion | 0.00511310553386146 |
| GO:0033279 | ribosomal subunit | 0.00511310553386146 |
| GO:0032991 | macromolecular complex | 0.00511310553386146 |
| GO:0006412 | translation | 0.00723930261923568 |
| GO:0005666 | DNA-directed RNA polymerase III complex | 0.0117906437470871 |
| GO:0009059 | macromolecule biosynthetic process | 0.0184646870897222 |
| GO:0044444 | cytoplasmic part | 0.02519769300812 |
| GO:0044249 | cellular biosynthetic process | 0.033176034383354 |
| GO:0000428 | DNA-directed RNA polymerase complex | 0.0357435504572228 |
| GO:0055029 | nuclear DNA-directed RNA polymerase complex | 0.0357435504572228 |
| GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity | 0.0357435504572228 |
| GO:0022884 | macromolecule transmembrane transporter activity | 0.0357435504572228 |
| GO:0030880 | RNA polymerase complex | 0.0357435504572228 |
| GO:0005843 | cytosolic small ribosomal subunit (sensu Eukaryota) | 0.0357435504572228 |
| GO:0044429 | mitochondrial part | 0.0357435504572228 |
| GO:0044446 | intracellular organelle part | 0.0357435504572228 |
| GO:0044422 | organelle part | 0.0357435504572228 |
| GO:0000315 | organellar large ribosomal subunit | 0.0357435504572228 |
| GO:0005762 | mitochondrial large ribosomal subunit | 0.0357435504572228 |
| GO:0009058 | biosynthetic process | 0.0357435504572228 |
| GO:0005741 | mitochondrial outer membrane | 0.0357435504572228 |
| GO:0008320 | protein transmembrane transporter activity | 0.0357435504572228 |
| GO:0031968 | organelle outer membrane | 0.0397758379675364 |
| GO:0019843 | rRNA binding | 0.0400371094597319 |
| GO:0010467 | gene expression | 0.0473908350928618 |
| GO:0015935 | small ribosomal subunit | 0.0485648897514198 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| animal cell | 1.67e-23 | 115 |
| eukaryotic cell | 1.67e-23 | 115 |
| somatic cell | 7.84e-23 | 118 |
| somatic stem cell | 1.09e-19 | 91 |
| multi fate stem cell | 1.09e-19 | 91 |
| stem cell | 1.58e-18 | 97 |
| non-terminally differentiated cell | 8.49e-17 | 49 |
| neural cell | 1.21e-15 | 43 |
| ectodermal cell | 1.23e-15 | 44 |
| neurectodermal cell | 1.23e-15 | 44 |
| embryonic cell | 3.67e-15 | 70 |
| electrically responsive cell | 6.62e-12 | 39 |
| electrically active cell | 6.62e-12 | 39 |
| CNS neuron (sensu Vertebrata) | 3.55e-11 | 23 |
| neuroblast (sensu Vertebrata) | 3.55e-11 | 23 |
| neuron | 8.38e-11 | 33 |
| neuronal stem cell | 8.38e-11 | 33 |
| neuroblast | 8.38e-11 | 33 |
| electrically signaling cell | 8.38e-11 | 33 |
| motile cell | 3.08e-10 | 54 |
| connective tissue cell | 3.24e-07 | 46 |
| mesenchymal cell | 3.24e-07 | 46 |
| Ontology term | p-value | n |
|---|---|---|
| nervous system | 1.42e-10 | 75 |
| central nervous system | 2.20e-10 | 73 |
| gray matter | 6.87e-10 | 34 |
| brain grey matter | 8.39e-08 | 29 |
| regional part of telencephalon | 8.39e-08 | 29 |
| telencephalon | 8.39e-08 | 29 |
| regional part of nervous system | 1.66e-07 | 54 |
| connective tissue | 3.24e-07 | 46 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.0854318 |
| MA0004.1 | 1.02263 |
| MA0006.1 | 1.24699 |
| MA0007.1 | 0.38073 |
| MA0009.1 | 0.82278 |
| MA0014.1 | 0.119217 |
| MA0017.1 | 0.726051 |
| MA0019.1 | 0.642876 |
| MA0024.1 | 0.779446 |
| MA0025.1 | 1.05446 |
| MA0027.1 | 2.46647 |
| MA0028.1 | 3.64201 |
| MA0029.1 | 0.757957 |
| MA0030.1 | 0.764448 |
| MA0031.1 | 0.729293 |
| MA0038.1 | 0.534262 |
| MA0040.1 | 0.835181 |
| MA0041.1 | 0.323687 |
| MA0042.1 | 0.311486 |
| MA0043.1 | 0.918718 |
| MA0046.1 | 0.858391 |
| MA0048.1 | 1.47862 |
| MA0050.1 | 0.431976 |
| MA0051.1 | 0.542972 |
| MA0052.1 | 0.84317 |
| MA0055.1 | 0.424109 |
| MA0056.1 | 0 |
| MA0057.1 | 0.258928 |
| MA0058.1 | 0.823526 |
| MA0059.1 | 0.849123 |
| MA0060.1 | 0.9744 |
| MA0061.1 | 0.194456 |
| MA0063.1 | 0 |
| MA0066.1 | 0.523573 |
| MA0067.1 | 1.16502 |
| MA0068.1 | 0.266547 |
| MA0069.1 | 0.843506 |
| MA0070.1 | 0.833895 |
| MA0071.1 | 0.431174 |
| MA0072.1 | 0.825495 |
| MA0073.1 | 3.85717e-05 |
| MA0074.1 | 0.488775 |
| MA0076.1 | 3.90074 |
| MA0077.1 | 0.804033 |
| MA0078.1 | 0.575205 |
| MA0081.1 | 0.338098 |
| MA0083.1 | 0.917931 |
| MA0084.1 | 1.49188 |
| MA0087.1 | 0.87515 |
| MA0088.1 | 1.11906 |
| MA0089.1 | 0 |
| MA0090.1 | 0.362551 |
| MA0091.1 | 0.407455 |
| MA0092.1 | 0.95209 |
| MA0093.1 | 1.30984 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.477594 |
| MA0101.1 | 0.324888 |
| MA0103.1 | 0.748482 |
| MA0105.1 | 0.35523 |
| MA0106.1 | 0.582805 |
| MA0107.1 | 0.266586 |
| MA0108.2 | 0.665343 |
| MA0109.1 | 0 |
| MA0111.1 | 0.375908 |
| MA0113.1 | 0.555251 |
| MA0114.1 | 0.561811 |
| MA0115.1 | 0.921497 |
| MA0116.1 | 1.24629 |
| MA0117.1 | 0.88947 |
| MA0119.1 | 0.868953 |
| MA0122.1 | 0.909168 |
| MA0124.1 | 1.11203 |
| MA0125.1 | 1.03833 |
| MA0130.1 | 0 |
| MA0131.1 | 1.54167 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.954884 |
| MA0136.1 | 0.508047 |
| MA0139.1 | 0.143341 |
| MA0140.1 | 0.477483 |
| MA0141.1 | 0.29014 |
| MA0142.1 | 0.714976 |
| MA0143.1 | 0.571221 |
| MA0144.1 | 1.07908 |
| MA0145.1 | 0.442138 |
| MA0146.1 | 0.148686 |
| MA0147.1 | 2.48306 |
| MA0148.1 | 0.410398 |
| MA0149.1 | 0.330018 |
| MA0062.2 | 4.63303 |
| MA0035.2 | 0.482026 |
| MA0039.2 | 0.0156581 |
| MA0138.2 | 0.630612 |
| MA0002.2 | 0.447007 |
| MA0137.2 | 1.42833 |
| MA0104.2 | 1.48162 |
| MA0047.2 | 0.533516 |
| MA0112.2 | 0.200175 |
| MA0065.2 | 0.0545595 |
| MA0150.1 | 0.380623 |
| MA0151.1 | 0 |
| MA0152.1 | 0.53362 |
| MA0153.1 | 0.971406 |
| MA0154.1 | 0.276788 |
| MA0155.1 | 0.0631765 |
| MA0156.1 | 0.763978 |
| MA0157.1 | 0.683365 |
| MA0158.1 | 0 |
| MA0159.1 | 0.214506 |
| MA0160.1 | 0.413266 |
| MA0161.1 | 0 |
| MA0162.1 | 0.0672805 |
| MA0163.1 | 0.0600297 |
| MA0164.1 | 0.508398 |
| MA0080.2 | 0.267388 |
| MA0018.2 | 0.51781 |
| MA0099.2 | 0.624421 |
| MA0079.2 | 0.00199657 |
| MA0102.2 | 1.5442 |
| MA0258.1 | 0.180934 |
| MA0259.1 | 1.08444 |
| MA0442.1 | 0 |
