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Coexpression cluster:C3101

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Full id: C3101_Fibroblast_Adipocyte_tenocyte_Pancreatic_Smooth_extraskeletal_mesenchymal



Phase1 CAGE Peaks

Hg19::chr11:121971132..121971166,-p1@MIR100HG
Hg19::chr11:121971176..121971195,-p2@MIR100HG
Hg19::chr11:121971257..121971264,-p4@MIR100HG


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
organism subdivision2.96e-23365
somite2.94e-2183
paraxial mesoderm2.94e-2183
presomitic mesoderm2.94e-2183
presumptive segmental plate2.94e-2183
trunk paraxial mesoderm2.94e-2183
presumptive paraxial mesoderm2.94e-2183
dermomyotome1.18e-1770
multilaminar epithelium1.13e-1682
muscle tissue9.32e-1663
musculature9.32e-1663
musculature of body9.32e-1663
skeletal muscle tissue1.13e-1561
striated muscle tissue1.13e-1561
myotome1.13e-1561
multi-tissue structure2.45e-15347
cell layer7.51e-15312
epithelium1.38e-14309
multi-cellular organism2.94e-14659
trunk mesenchyme1.60e-12143
ectoderm-derived structure4.43e-11169
ectoderm1.83e-10173
presumptive ectoderm1.83e-10173
anatomical system2.03e-10625
head2.49e-10123
anatomical group3.30e-10626
surface structure6.04e-1095
anterior region of body1.11e-09129
craniocervical region1.11e-09129
anatomical cluster2.56e-09286
neural plate4.10e-0986
presumptive neural plate4.10e-0986
regional part of nervous system5.93e-0994
nervous system5.93e-0994
splanchnic layer of lateral plate mesoderm1.48e-0884
integument1.65e-0845
integumental system1.65e-0845
neurectoderm2.68e-0890
trunk2.99e-08216
central nervous system3.04e-0882
vasculature3.48e-0879
vascular system3.48e-0879
artery5.71e-0842
arterial blood vessel5.71e-0842
arterial system5.71e-0842
embryo1.24e-07612
anatomical conduit1.54e-07241
embryonic structure1.70e-07605
developing anatomical structure1.70e-07605
pre-chordal neural plate1.70e-0761
skin of body1.82e-0740
blood vessel2.03e-0760
epithelial tube open at both ends2.03e-0760
blood vasculature2.03e-0760
vascular cord2.03e-0760
regional part of brain2.54e-0759
tube2.73e-07194
germ layer3.28e-07604
embryonic tissue3.28e-07604
presumptive structure3.28e-07604
epiblast (generic)3.28e-07604
systemic artery3.34e-0733
systemic arterial system3.34e-0733
neural tube7.83e-0757
neural rod7.83e-0757
future spinal cord7.83e-0757
neural keel7.83e-0757


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.