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Coexpression cluster:C2092

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Full id: C2092_splenic_Endothelial_Lymphatic_adenocarcinoma_Renal_small_lymphangiectasia



Phase1 CAGE Peaks

Hg19::chr11:108743594..108743616,+p@chr11:108743594..108743616
+
Hg19::chr19:42007093..42007107,-p@chr19:42007093..42007107
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Hg19::chr19:42007124..42007140,-p@chr19:42007124..42007140
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Hg19::chr3:11535651..11535655,-p@chr3:11535651..11535655
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.22e-20115
anatomical conduit3.31e-17241
endothelium5.54e-1718
blood vessel endothelium5.54e-1718
cardiovascular system endothelium5.54e-1718
simple squamous epithelium8.46e-1622
anatomical cluster1.40e-15286
tube1.59e-14194
squamous epithelium6.53e-1325
neural tube1.64e-0957
neural rod1.64e-0957
future spinal cord1.64e-0957
neural keel1.64e-0957
endothelial tube6.21e-099
arterial system endothelium6.21e-099
endothelium of artery6.21e-099
cell layer6.76e-09312
epithelium1.30e-08309
neural plate3.84e-0886
presumptive neural plate3.84e-0886
telencephalon6.13e-0834
neurectoderm8.35e-0890
vessel8.95e-0869
regional part of telencephalon1.03e-0733
gray matter1.24e-0734
brain grey matter1.24e-0734
regional part of forebrain1.54e-0741
forebrain1.54e-0741
future forebrain1.54e-0741
regional part of brain1.91e-0759
cerebral hemisphere2.80e-0732
anterior neural tube3.50e-0742
anatomical group4.60e-07626
regional part of cerebral cortex6.33e-0722
central nervous system7.03e-0782


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.