Personal tools

Coexpression cluster:C1628

From FANTOM5_SSTAR

Revision as of 17:29, 8 August 2012 by Autoedit (talk | contribs)
Jump to: navigation, search


Full id: C1628_mesodermal_spinal_locus_parietal_temporal_medulla_thalamus



Phase1 CAGE Peaks

Hg19::chr11:24518511..24518530,+p6@LUZP2
Hg19::chr11:24518538..24518620,+p1@LUZP2
Hg19::chr11:24518633..24518649,+p4@LUZP2
Hg19::chr11:24518654..24518698,+p2@LUZP2
Hg19::chr11:24518723..24518745,+p7@LUZP2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
regional part of nervous system8.09e-4394
nervous system8.09e-4394
central nervous system2.30e-4182
neural tube1.87e-3957
neural rod1.87e-3957
future spinal cord1.87e-3957
neural keel1.87e-3957
neural plate5.13e-3586
presumptive neural plate5.13e-3586
neurectoderm4.20e-3390
adult organism5.11e-33115
regional part of brain6.43e-3359
brain4.97e-3269
future brain4.97e-3269
regional part of forebrain1.34e-3141
forebrain1.34e-3141
future forebrain1.34e-3141
anterior neural tube2.04e-3042
anterior region of body1.93e-29129
craniocervical region1.93e-29129
head4.11e-29123
ectoderm-derived structure2.34e-28169
ectoderm1.79e-27173
presumptive ectoderm1.79e-27173
gray matter2.60e-2634
brain grey matter2.60e-2634
telencephalon4.86e-2634
pre-chordal neural plate1.47e-2561
regional part of telencephalon3.46e-2533
cerebral hemisphere2.71e-2432
regional part of cerebral cortex8.96e-2122
neocortex5.77e-1920
cerebral cortex2.95e-1825
pallium2.95e-1825
organ part1.35e-12219
organism subdivision1.74e-12365
tube1.09e-11194
multi-tissue structure1.17e-10347
posterior neural tube5.11e-1015
chordal neural plate5.11e-1015
nucleus of brain1.28e-099
neural nucleus1.28e-099
basal ganglion1.56e-099
nuclear complex of neuraxis1.56e-099
aggregate regional part of brain1.56e-099
collection of basal ganglia1.56e-099
cerebral subcortex1.56e-099
anatomical conduit1.61e-09241
multi-cellular organism2.94e-09659
embryo1.17e-08612
temporal lobe3.61e-087
anatomical cluster3.76e-08286
segmental subdivision of nervous system4.28e-0813
telencephalic nucleus1.09e-077
segmental subdivision of hindbrain2.66e-0712
hindbrain2.66e-0712
presumptive hindbrain2.66e-0712
epithelium3.49e-07309
cell layer4.51e-07312
organ5.36e-07511
diencephalon6.05e-077
future diencephalon6.05e-077
brainstem7.31e-078


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.