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Coexpression cluster:C962

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Full id: C962_Renal_Endothelial_Preadipocyte_Adipocyte_Hepatic_chorionic_tenocyte



Phase1 CAGE Peaks

Hg19::chr9:130580482..130580516,-p@chr9:130580482..130580516
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Hg19::chr9:130582222..130582259,-p@chr9:130582222..130582259
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Hg19::chr9:130586651..130586690,+p@chr9:130586651..130586690
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Hg19::chr9:130587552..130587570,-p11@ENG
Hg19::chr9:130587571..130587595,-p8@ENG
Hg19::chr9:130588024..130588035,-p12@ENG
Hg19::chr9:130588904..130588928,-p@chr9:130588904..130588928
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Hg19::chr9:130605421..130605442,-p@chr9:130605421..130605442
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Hg19::chr9:130605459..130605479,-p@chr9:130605459..130605479
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
non-terminally differentiated cell3.17e-19180
mesodermal cell7.11e-18119
endothelial cell3.17e-1635
fibroblast2.30e-1575
endothelial cell of vascular tree6.21e-1424
multi fate stem cell7.43e-14430
meso-epithelial cell6.85e-1344
somatic stem cell2.49e-12436
stem cell5.40e-11444
blood vessel endothelial cell1.02e-1018
embryonic blood vessel endothelial progenitor cell1.02e-1018
muscle precursor cell1.10e-1057
myoblast1.10e-1057
multi-potent skeletal muscle stem cell1.10e-1057
contractile cell2.45e-1059
muscle cell1.38e-0954
lining cell1.14e-0857
barrier cell1.14e-0857
somatic cell2.06e-08591
preadipocyte3.03e-0812
smooth muscle cell3.84e-0842
smooth muscle myoblast3.84e-0842
vascular associated smooth muscle cell3.74e-0732
electrically responsive cell3.78e-0760
electrically active cell3.78e-0760
monopoietic cell4.47e-0763
monocyte4.47e-0763
monoblast4.47e-0763
promonocyte4.47e-0763
macrophage dendritic cell progenitor6.11e-0765
Uber Anatomy
Ontology termp-valuen
splanchnic layer of lateral plate mesoderm3.56e-2484
vessel2.37e-2369
vasculature5.20e-2379
vascular system5.20e-2379
circulatory system2.02e-20113
blood vessel2.46e-2060
epithelial tube open at both ends2.46e-2060
blood vasculature2.46e-2060
vascular cord2.46e-2060
lateral plate mesoderm7.71e-20216
cardiovascular system1.65e-19110
epithelial tube4.18e-15118
musculoskeletal system4.23e-15167
artery8.90e-1542
arterial blood vessel8.90e-1542
arterial system8.90e-1542
mesoderm2.65e-14448
mesoderm-derived structure2.65e-14448
presumptive mesoderm2.65e-14448
multi-cellular organism5.86e-14659
systemic artery3.32e-1233
systemic arterial system3.32e-1233
dermomyotome4.15e-1270
somite1.14e-1183
paraxial mesoderm1.14e-1183
presomitic mesoderm1.14e-1183
presumptive segmental plate1.14e-1183
trunk paraxial mesoderm1.14e-1183
presumptive paraxial mesoderm1.14e-1183
anatomical system1.35e-11625
anatomical group2.54e-11626
endothelium1.02e-1018
blood vessel endothelium1.02e-1018
cardiovascular system endothelium1.02e-1018
skeletal muscle tissue1.46e-1061
striated muscle tissue1.46e-1061
myotome1.46e-1061
muscle tissue1.79e-1063
musculature1.79e-1063
musculature of body1.79e-1063
multilaminar epithelium3.54e-0982
unilaminar epithelium4.95e-09138
primary circulatory organ5.44e-0927
squamous epithelium1.83e-0825
simple squamous epithelium2.38e-0822
aorta2.58e-0821
aortic system2.58e-0821
heart3.89e-0824
primitive heart tube3.89e-0824
primary heart field3.89e-0824
anterior lateral plate mesoderm3.89e-0824
heart tube3.89e-0824
heart primordium3.89e-0824
cardiac mesoderm3.89e-0824
cardiogenic plate3.89e-0824
heart rudiment3.89e-0824
tissue8.66e-08787
anatomical cluster1.37e-07286
trunk mesenchyme2.74e-07143


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.