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Coexpression cluster:C1465

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Full id: C1465_Mast_Preadipocyte_Fibroblast_Smooth_Chondrocyte_basal_Osteoblast



Phase1 CAGE Peaks

Hg19::chr1:160312998..160313024,-p2@COPA
Hg19::chr1:160313025..160313072,-p1@COPA
Hg19::chr4:119757222..119757238,-p2@SEC24D
Hg19::chr4:119757239..119757305,-p1@SEC24D
Hg19::chr4:119757322..119757334,-p3@SEC24D
Hg19::chr4:83812268..83812401,-p1@SEC31A


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0030120vesicle coat1.59360715573632e-07
GO:0030662coated vesicle membrane1.59360715573632e-07
GO:0005798Golgi-associated vesicle2.67292367563503e-07
GO:0030659cytoplasmic vesicle membrane4.8489276073581e-07
GO:0044433cytoplasmic vesicle part4.8489276073581e-07
GO:0012506vesicle membrane4.8489276073581e-07
GO:0030117membrane coat4.8489276073581e-07
GO:0048475coated membrane4.8489276073581e-07
GO:0030135coated vesicle8.82004274168316e-07
GO:0030127COPII vesicle coat3.68578464954729e-06
GO:0012507ER to Golgi transport vesicle membrane3.68578464954729e-06
GO:0030134ER to Golgi transport vesicle4.54798519481905e-06
GO:0016023cytoplasmic membrane-bound vesicle7.87888560646397e-06
GO:0031988membrane-bound vesicle7.87888560646397e-06
GO:0000139Golgi membrane8.20133629517297e-06
GO:0046903secretion8.95670736238786e-06
GO:0044431Golgi apparatus part1.07485746738754e-05
GO:0031410cytoplasmic vesicle1.07485746738754e-05
GO:0031982vesicle1.07485746738754e-05
GO:0030658transport vesicle membrane1.20808507966572e-05
GO:0030660Golgi-associated vesicle membrane1.22723693440234e-05
GO:0006888ER to Golgi vesicle-mediated transport1.84191560341748e-05
GO:0016192vesicle-mediated transport2.45590807920104e-05
GO:0005794Golgi apparatus3.55255879566779e-05
GO:0030133transport vesicle4.05661523916162e-05
GO:0015031protein transport6.34964434528897e-05
GO:0005783endoplasmic reticulum6.7748719125613e-05
GO:0046907intracellular transport6.7748719125613e-05
GO:0045184establishment of protein localization6.7748719125613e-05
GO:0048193Golgi vesicle transport6.7748719125613e-05
GO:0008104protein localization7.27991888716605e-05
GO:0033036macromolecule localization8.23717077444704e-05
GO:0012505endomembrane system8.37282444874029e-05
GO:0051649establishment of cellular localization9.90411355731548e-05
GO:0051641cellular localization0.000103768176789829
GO:0031090organelle membrane0.00024395131137356
GO:0045045secretory pathway0.000401112297492283
GO:0032940secretion by cell0.000597908532731506
GO:0030157pancreatic juice secretion0.00113202077726421
GO:0006886intracellular protein transport0.00179641366272567
GO:0016043cellular component organization and biogenesis0.00218737270485908
GO:0030126COPI vesicle coat0.00307924290153726
GO:0030663COPI coated vesicle membrane0.00307924290153726
GO:0030137COPI-coated vesicle0.00341029397521763
GO:0007589fluid secretion0.00353055334416461
GO:0006810transport0.00356800737070301
GO:0022600digestive system process0.00356800737070301
GO:0044446intracellular organelle part0.00360426233566905
GO:0044422organelle part0.00360426233566905
GO:0051234establishment of localization0.00360426233566905
GO:0051179localization0.00449716529632016
GO:0044444cytoplasmic part0.0047467189745629
GO:0007586digestion0.0157850363922107
GO:0005737cytoplasm0.019776990414091
GO:0050878regulation of body fluid levels0.0199968336228727
GO:0044425membrane part0.0209982178169082
GO:0008565protein transporter activity0.0237513622530376
GO:0005792microsome0.0245486292312923
GO:0042598vesicular fraction0.0251701198432801
GO:0043231intracellular membrane-bound organelle0.0283199098597437
GO:0043227membrane-bound organelle0.0283199098597437
GO:0051082unfolded protein binding0.0283199098597437
GO:0005515protein binding0.0295556769216537
GO:0005179hormone activity0.0297519573752465
GO:0005625soluble fraction0.0315733359434466
GO:0016020membrane0.035777524468533
GO:0006461protein complex assembly0.0443511685631897
GO:0006457protein folding0.0443511685631897
GO:0043229intracellular organelle0.045484256688062
GO:0043226organelle0.045484256688062



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
somite5.52e-2183
paraxial mesoderm5.52e-2183
presomitic mesoderm5.52e-2183
presumptive segmental plate5.52e-2183
trunk paraxial mesoderm5.52e-2183
presumptive paraxial mesoderm5.52e-2183
musculoskeletal system1.13e-19167
splanchnic layer of lateral plate mesoderm1.45e-1884
dermomyotome4.68e-1870
vasculature1.08e-1779
vascular system1.08e-1779
muscle tissue2.94e-1663
musculature2.94e-1663
musculature of body2.94e-1663
multilaminar epithelium2.98e-1682
skeletal muscle tissue4.54e-1661
striated muscle tissue4.54e-1661
myotome4.54e-1661
mesoderm4.99e-16448
mesoderm-derived structure4.99e-16448
presumptive mesoderm4.99e-16448
artery9.89e-1642
arterial blood vessel9.89e-1642
arterial system9.89e-1642
blood vessel1.84e-1560
epithelial tube open at both ends1.84e-1560
blood vasculature1.84e-1560
vascular cord1.84e-1560
vessel1.89e-1569
cardiovascular system3.12e-14110
unilaminar epithelium1.65e-13138
trunk mesenchyme2.22e-13143
circulatory system3.01e-13113
systemic artery5.14e-1333
systemic arterial system5.14e-1333
epithelial tube1.46e-11118
multi-cellular organism3.22e-11659
connective tissue3.98e-11375
lateral plate mesoderm3.08e-10216
anatomical group5.23e-10626
anatomical system8.87e-10625
integument2.91e-0845
integumental system2.91e-0845
aorta9.63e-0821
aortic system9.63e-0821
trunk1.33e-07216
surface structure1.62e-0795
skin of body1.73e-0740


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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