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Property:Comment

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Consider adding grouping class for TAO:0001995  +
Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID: 19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis.  +
{{{comment}}}  +
TODO - split body and mc organism? body continues after death stage  +
todo - move metadata to GO and obsolete this class. Note the inconsistency between the usage of the label 'cell component' in GO and CARO  +
Editor note: revise after CARO2. todo - check the inclusion of FMA 'cardinal body part here', and check child terms for consistency  +
see also conceptus extraembryonic component in EHDAA2  +
This class was sourced from CARO, which was initially sourced from FMA. Nomenclature changes have been made. Note also AEO introduces a class AEO:0000013 'single-cell tissue'  +
This class was created automatically from a combination of ontologies  +
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These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma.  +
Derived from UBERON:0002342 neural crest.  +
Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)  +
Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative.  +
Megakaryocytes are reportedly CD181-positive and CD182-positive.  +
Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID: 19243617). GMPs are reportedly CD34-positive, CD38-positive, CD45RA-positive, and CD123-positive.  +
Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.  +
These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive.  +
t1  +
t2  +