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UBERON:0004715

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Name:annulus fibrosus disci intervertebralis
Definition:"The ring of fibrocartilage and fibrous tissue forming the circumference of the intervertebral disc; surrounds the nucleus pulposus, which is prone to herniation when the annulus fibrosus is compromised." [BTO:0003629, Wikipedia:Annulus_fibrosus_disci_intervertebralis]
Xrefs:
links:

BTO:0003629
FMA:13551
[ Cervical_vertebra_english.png Cervical_vertebra_english.png]
[ 200px-Cervical_vertebra_english.png 200px-Cervical_vertebra_english.png]
MA:0000111

Wikipedia:Annulus_fibrosus_disci_intervertebralis
Synonyms: "annulus fibrosus" BROAD [MA:0000111]
"annulus fibrosus of intervertebral disc" RELATED [BTO:0003629]
"anulus fibrosus (diskus intervertebralis)" EXACT [FMA:13551]
"anulus fibrosus of intervertebral disk" EXACT [FMA:13551]
"fibrous ring of intervertebral disc" RELATED [BTO:0003629]

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0004120(mesoderm-derived structure),UBERON:0006444(annulus fibrosus)
part_of:UBERON:0001066(intervertebral disk)



Children

part of:CL:0002602 (annulus pulposus cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0004715 (annulus fibrosus disci intervertebralis), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.68e-99FFCP PHASE1:Hg19::chr1:78769549..78769554,+#_333345ed53fb4f0a81b1747d4b4647e7p5@PTGFR
5.68e-99FFCP PHASE2:Hg19::chr1:78769549..78769554,+#_333345ed53fb4f0a81b1747d4b4647e7p5@PTGFR
1.55e-98FFCP PHASE1:Hg19::chr13:24914614..24914622,-#_e1f9f2c8be02387e5badb6558d0a6c40p@chr13:24914614..24914622, -
1.55e-98FFCP PHASE2:Hg19::chr13:24914614..24914622,-#_e1f9f2c8be02387e5badb6558d0a6c40p@chr13:24914614..24914622, -
2.34e-79FFCP PHASE2:Hg19::chr9:114135497..114135526,-#_d0d52a064114a9888077e012de8fcafcp@chr9:114135497..114135526, -
2.34e-79FFCP PHASE1:Hg19::chr9:114135497..114135526,-#_d0d52a064114a9888077e012de8fcafcp@chr9:114135497..114135526, -
1.45e-66FFCP PHASE2:Hg19::chr3:174737010..174737023,+#_852493bdfed9d82fc703fc19da330256p@chr3:174737010..174737023, +
1.45e-66FFCP PHASE1:Hg19::chr3:174737010..174737023,+#_852493bdfed9d82fc703fc19da330256p@chr3:174737010..174737023, +
2.84e-66FFCP PHASE1:Hg19::chr2:241897189..241897221,-#_264841e7e27f90e6bbf70c7502a384a2p@chr2:241897189..241897221, -
2.84e-66FFCP PHASE2:Hg19::chr2:241897189..241897221,-#_264841e7e27f90e6bbf70c7502a384a2p@chr2:241897189..241897221, -
1.13e-57FFCP PHASE2:Hg19::chr10:81923378..81923389,-#_10e197d5680f5c65bb6b280d06d4e454p@chr10:81923378..81923389, -
1.13e-57FFCP PHASE2:Hg19::chr20:21687260..21687270,+#_10e197d5680f5c65bb6b280d06d4e454p3@PAX1
1.13e-57FFCP PHASE1:Hg19::chr20:21687193..21687206,+#_10e197d5680f5c65bb6b280d06d4e454p4@PAX1
1.13e-57FFCP PHASE1:Hg19::chr20:21687260..21687270,+#_10e197d5680f5c65bb6b280d06d4e454p3@PAX1
1.13e-57FFCP PHASE1:Hg19::chr10:81923378..81923389,-#_10e197d5680f5c65bb6b280d06d4e454p@chr10:81923378..81923389, -
1.13e-57FFCP PHASE2:Hg19::chr20:21687193..21687206,+#_10e197d5680f5c65bb6b280d06d4e454p4@PAX1
1.14e-50FFCP PHASE2:Hg19::chr4:13546583..13546593,-#_fceed533031de90346222bab34851f3ap3@NKX3-2
1.14e-50FFCP PHASE1:Hg19::chr4:13546583..13546593,-#_fceed533031de90346222bab34851f3ap3@NKX3-2
1.46e-50FFCP PHASE1:Hg19::chr4:13546130..13546145,-#_95a85ef254985bf03a9448cac19ebfcfp4@NKX3-2
1.46e-50FFCP PHASE2:Hg19::chr4:13546130..13546145,-#_95a85ef254985bf03a9448cac19ebfcfp4@NKX3-2
2.74e-50FFCP PHASE1:Hg19::chr16:4421890..4421912,-#_149209327ac6d74617d97edf6627f529p@chr16:4421890..4421912, -
2.74e-50FFCP PHASE2:Hg19::chr16:4421890..4421912,-#_149209327ac6d74617d97edf6627f529p@chr16:4421890..4421912, -
3.19e-45FFCP PHASE2:Hg19::chr2:241897125..241897142,-#_f689e61695242411916fcecc37abc6cfp@chr2:241897125..241897142, -
3.19e-45FFCP PHASE1:Hg19::chr2:241897125..241897142,-#_f689e61695242411916fcecc37abc6cfp@chr2:241897125..241897142, -
1.22e-44FFCP PHASE2:Hg19::chr3:80727046..80727051,-#_aadda54c88d7d2857f318daf81cc83acp@chr3:80727046..80727051, -
1.22e-44FFCP PHASE1:Hg19::chr3:80727046..80727051,-#_aadda54c88d7d2857f318daf81cc83acp@chr3:80727046..80727051, -
5.99e-41FFCP PHASE1:Hg19::chr5:30104176..30104187,-#_2333cd7c05a88c9c84e102fc3fa80476p@chr5:30104176..30104187, -
5.99e-41FFCP PHASE2:Hg19::chr5:30104176..30104187,-#_2333cd7c05a88c9c84e102fc3fa80476p@chr5:30104176..30104187, -
3.01e-40FFCP PHASE2:Hg19::chr1:19778678..19778689,-#_6e6c992fad67ce1399b09e5a02c248bfp@chr1:19778678..19778689, -
3.01e-40FFCP PHASE1:Hg19::chr1:19778678..19778689,-#_6e6c992fad67ce1399b09e5a02c248bfp@chr1:19778678..19778689, -
1.3e-37FFCP PHASE1:Hg19::chr20:21695435..21695452,+#_8d4ab8f1a59f5296b266eb3975d153f5p@chr20:21695435..21695452, +
1.3e-37FFCP PHASE2:Hg19::chr20:21695435..21695452,+#_8d4ab8f1a59f5296b266eb3975d153f5p@chr20:21695435..21695452, +
3.94e-37FFCP PHASE1:Hg19::chr16:70795228..70795237,+#_d7bf323642bf9e91a209b48c2fa07776p@chr16:70795228..70795237, +
3.94e-37FFCP PHASE2:Hg19::chr16:70795228..70795237,+#_d7bf323642bf9e91a209b48c2fa07776p@chr16:70795228..70795237, +
8.2e-37FFCP PHASE1:Hg19::chr14:23574186..23574212,-#_b5b42383f35c81d980643f9f6b2d43b0p1@uc010aki.1
8.2e-37FFCP PHASE2:Hg19::chr14:23574186..23574212,-#_b5b42383f35c81d980643f9f6b2d43b0p1@uc010aki.1
1.18e-36FFCP PHASE2:Hg19::chr8:27455513..27455516,+#_52394b8f6672cd8f284c7638aa5fb4d9p7@CU679734
1.18e-36FFCP PHASE1:Hg19::chr8:27455513..27455516,+#_52394b8f6672cd8f284c7638aa5fb4d9p7@CU679734
7.05e-34FFCP PHASE2:Hg19::chr14:23574164..23574179,-#_d347104c7eac1d787803b246afd6da21p3@uc010aki.1
7.05e-34FFCP PHASE1:Hg19::chr14:23574164..23574179,-#_d347104c7eac1d787803b246afd6da21p3@uc010aki.1
8.05e-30FFCP PHASE1:Hg19::chr11:66724317..66724340,-#_0292605eb67fd93fbad2d5e497c0a6f6p@chr11:66724317..66724340, -
8.05e-30FFCP PHASE2:Hg19::chr11:66724317..66724340,-#_0292605eb67fd93fbad2d5e497c0a6f6p@chr11:66724317..66724340, -
2.22e-29FFCP PHASE1:Hg19::chr2:53161632..53161661,-#_47107708cd4e60511a6fdfa31fc014dfp@chr2:53161632..53161661, -
2.22e-29FFCP PHASE2:Hg19::chr2:53161632..53161661,-#_47107708cd4e60511a6fdfa31fc014dfp@chr2:53161632..53161661, -
5.41e-28FFCP PHASE1:Hg19::chr2:242004292..242004308,+#_79dd5ce32003b37fb9c4be91c2e4f605p15@SNED1
5.41e-28FFCP PHASE2:Hg19::chr2:242004292..242004308,+#_79dd5ce32003b37fb9c4be91c2e4f605p15@SNED1
7.1e-28FFCP PHASE2:Hg19::chr1:19811132..19811155,-#_0123bbb366c4ea5b5ff803aecefa897cp20@CAPZB
7.1e-28FFCP PHASE1:Hg19::chr1:19811132..19811155,-#_0123bbb366c4ea5b5ff803aecefa897cp20@CAPZB
2.09e-27FFCP PHASE2:Hg19::chr8:25337491..25337504,+#_27082e0b86db56eefdc7b02c1395082cp@chr8:25337491..25337504, +
2.09e-27FFCP PHASE1:Hg19::chr8:25337491..25337504,+#_27082e0b86db56eefdc7b02c1395082cp@chr8:25337491..25337504, +
3.59e-26FFCP PHASE1:Hg19::chr2:241897363..241897398,+#_6c23e8f7a644ef0038f60a21b871d21cp@chr2:241897363..241897398, +
3.59e-26FFCP PHASE2:Hg19::chr2:241897363..241897398,+#_6c23e8f7a644ef0038f60a21b871d21cp@chr2:241897363..241897398, +
3.89e-25FFCP PHASE2:Hg19::chr6:158490457..158490470,+#_1c3e6d69aa892b413d8c8e96ebacecc8p10@SYNJ2
3.89e-25FFCP PHASE1:Hg19::chr6:158490457..158490470,+#_1c3e6d69aa892b413d8c8e96ebacecc8p10@SYNJ2
5.58e-25FFCP PHASE2:Hg19::chr7:18832801..18832816,+#_ce7cfb7c988cd73564f3be2d7ad2a699p21@HDAC9
5.58e-25FFCP PHASE1:Hg19::chr7:18832801..18832816,+#_ce7cfb7c988cd73564f3be2d7ad2a699p21@HDAC9
1.02e-24FFCP PHASE2:Hg19::chr9:16138889..16138902,-#_3e00d39d0e7268d51c3a1bba301de080p@chr9:16138889..16138902, -
1.02e-24FFCP PHASE1:Hg19::chr9:16138889..16138902,-#_3e00d39d0e7268d51c3a1bba301de080p@chr9:16138889..16138902, -
1.45e-24FFCP PHASE1:Hg19::chr2:241938405..241938416,+#_d48b0ae0646f3913cf8ded983154488ep@chr2:241938405..241938416, +
1.45e-24FFCP PHASE2:Hg19::chr2:241938405..241938416,+#_d48b0ae0646f3913cf8ded983154488ep@chr2:241938405..241938416, +
2.34e-24FFCP PHASE2:Hg19::chr8:78311303..78311320,+#_a2d03fbdff24a5793f77f2e0829f5aecp2@ENST00000518706
2.34e-24FFCP PHASE1:Hg19::chr8:78311303..78311320,+#_a2d03fbdff24a5793f77f2e0829f5aecp2@ENST00000518706
6.77e-24FFCP PHASE1:Hg19::chr21:39705383..39705394,-#_8d0930cf9570d0b7b1a188ceb141c097p1@ENST00000436845
6.77e-24FFCP PHASE2:Hg19::chr21:39705383..39705394,-#_8d0930cf9570d0b7b1a188ceb141c097p1@ENST00000436845
8.02e-24FFCP PHASE1:Hg19::chr17:38655950..38655954,+#_3cc1740f16654116d7658aeb4ca6634dp@chr17:38655950..38655954, +
8.02e-24FFCP PHASE2:Hg19::chr17:38655950..38655954,+#_3cc1740f16654116d7658aeb4ca6634dp@chr17:38655950..38655954, +
1.13e-23FFCP PHASE1:Hg19::chr14:61190754..61190776,-#_9c0883e03259d40cfcc6aa067871cf2cp6@SIX4
1.13e-23FFCP PHASE2:Hg19::chr14:61190754..61190776,-#_9c0883e03259d40cfcc6aa067871cf2cp6@SIX4
1.78e-23FFCP PHASE2:Hg19::chr1:78695298..78695311,+#_879616fa48ca04e4815550e380b6fbf1p1@ENST00000413519
1.78e-23FFCP PHASE1:Hg19::chr1:78695298..78695311,+#_879616fa48ca04e4815550e380b6fbf1p1@ENST00000413519
1.14e-21FFCP PHASE2:Hg19::chr11:60610073..60610090,+#_4351b2f2a1caa0da1a15414b35275476p6@CCDC86
1.14e-21FFCP PHASE1:Hg19::chr11:60610073..60610090,+#_4351b2f2a1caa0da1a15414b35275476p6@CCDC86
1.53e-21FFCP PHASE2:Hg19::chr7:18832913..18832946,+#_353a64790a786512601676efc29516f1p19@HDAC9
1.53e-21FFCP PHASE1:Hg19::chr7:18832913..18832946,+#_353a64790a786512601676efc29516f1p19@HDAC9
3.47e-21FFCP PHASE1:Hg19::chr20:30181389..30181408,+#_c49b3932bea6fd2027936d70ffe6689cp@chr20:30181389..30181408, +
3.47e-21FFCP PHASE2:Hg19::chr20:30181389..30181408,+#_c49b3932bea6fd2027936d70ffe6689cp@chr20:30181389..30181408, +
3.81e-21FFCP PHASE1:Hg19::chr3:158384350..158384362,-#_f25666c976a61758b0969e91c1e5104fp@chr3:158384350..158384362, -
3.81e-21FFCP PHASE2:Hg19::chr3:158384350..158384362,-#_f25666c976a61758b0969e91c1e5104fp@chr3:158384350..158384362, -
4.66e-21FFCP PHASE1:Hg19::chr18:12012068..12012098,+#_63b0a931f86a9b8b6762f75c145c24dcp@chr18:12012068..12012098, +
4.66e-21FFCP PHASE2:Hg19::chr18:12012068..12012098,+#_63b0a931f86a9b8b6762f75c145c24dcp@chr18:12012068..12012098, +
5.2e-21FFCP PHASE2:Hg19::chr7:158224707..158224729,-#_524322f6067db0eca272fb8abc482a98p@chr7:158224707..158224729, -
5.2e-21FFCP PHASE1:Hg19::chr7:158224707..158224729,-#_524322f6067db0eca272fb8abc482a98p@chr7:158224707..158224729, -
6.96e-21FFCP PHASE1:Hg19::chr2:158345440..158345449,-#_d4822a5754313c8c6911788d317429fdp9@CYTIP
6.96e-21FFCP PHASE2:Hg19::chr2:158345440..158345449,-#_d4822a5754313c8c6911788d317429fdp9@CYTIP
6.96e-21FFCP PHASE1:Hg19::chr11:108743668..108743675,+#_d4822a5754313c8c6911788d317429fdp@chr11:108743668..108743675, +
6.96e-21FFCP PHASE2:Hg19::chr11:108743668..108743675,+#_d4822a5754313c8c6911788d317429fdp@chr11:108743668..108743675, +
8.49e-21FFCP PHASE2:Hg19::chr6:158490395..158490407,+#_f0723edc7fe2b38c1da995402ef64cb1p9@SYNJ2
8.49e-21FFCP PHASE1:Hg19::chr6:158490395..158490407,+#_f0723edc7fe2b38c1da995402ef64cb1p9@SYNJ2
2.74e-20FFCP PHASE1:Hg19::chr1:65888177..65888194,+#_4d92b337139f00bb3868f2443d7628c1p@chr1:65888177..65888194, +
2.74e-20FFCP PHASE2:Hg19::chr1:65888177..65888194,+#_4d92b337139f00bb3868f2443d7628c1p@chr1:65888177..65888194, +
1.64e-19FFCP PHASE1:Hg19::chr19:14223369..14223385,-#_cd0c272e696021e8e02254770220161ap5@PRKACA
1.64e-19FFCP PHASE2:Hg19::chr19:14223369..14223385,-#_cd0c272e696021e8e02254770220161ap5@PRKACA
2.38e-19FFCP PHASE2:Hg19::chr9:113798560..113798572,-#_af45d57e44a258eaf1469fde787641b9p34@LPAR1
2.38e-19FFCP PHASE1:Hg19::chr9:113798560..113798572,-#_af45d57e44a258eaf1469fde787641b9p34@LPAR1
4.53e-19FFCP PHASE1:Hg19::chr17:73688878..73688882,+#_7141412376b0e54d11e5239c5f272bf5p@chr17:73688878..73688882, +
4.53e-19FFCP PHASE2:Hg19::chr17:73688878..73688882,+#_7141412376b0e54d11e5239c5f272bf5p@chr17:73688878..73688882, +
6.53e-19FFCP PHASE2:Hg19::chr3:58572689..58572703,-#_a20e88b220b4e1aa57948cee9553dea2p6@FAM107A
6.53e-19FFCP PHASE1:Hg19::chr3:58572689..58572703,-#_a20e88b220b4e1aa57948cee9553dea2p6@FAM107A
7.03e-19FFCP PHASE1:Hg19::chr1:78695274..78695292,+#_8783b72ac87583cae0c54c5355489343p1@MGC27382
7.03e-19FFCP PHASE2:Hg19::chr1:78695274..78695292,+#_8783b72ac87583cae0c54c5355489343p1@MGC27382

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