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MCL coexpression mm9:1612

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Phase1 CAGE Peaks

 Short description
Mm9::chr12:105197088..105197099,-p4@Serpina1e
Mm9::chr12:105197149..105197155,-p5@Serpina1e
Mm9::chr5:148369358..148369365,-p@chr5:148369358..148369365
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Mm9::chr5:31271010..31271019,+p2@Tcf23
Mm9::chr5:31271028..31271040,+p1@Tcf23


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004867serine-type endopeptidase inhibitor activity0.042490202831952
GO:0004866endopeptidase inhibitor activity0.042490202831952
GO:0030414protease inhibitor activity0.042490202831952
GO:0004857enzyme inhibitor activity0.0448897475434736



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
female reproductive system4.19e-349
female reproductive organ2.15e-298
female organism9.70e-2811
reproductive structure5.03e-2126
reproductive system5.03e-2126
internal genitalia3.78e-199
reproductive organ9.01e-1924
internal female genitalia4.53e-165
female gonad2.98e-153
embryonic uterus1.03e-114
uterus1.03e-114
renal system3.08e-1119
urinary system structure9.66e-0918
kidney4.96e-0814
kidney mesenchyme4.96e-0814
upper urinary tract4.96e-0814
kidney rudiment4.96e-0814
kidney field4.96e-0814
epididymis2.72e-073
excretory tube2.72e-073
mesonephric epithelium2.72e-073
mesonephric tubule2.72e-073
nephric duct2.72e-073
kidney epithelium2.72e-073
renal duct2.72e-073
mesonephric duct2.72e-073
pronephric duct2.72e-073
external genitalia6.12e-0717
indifferent external genitalia6.12e-0717
indifferent gonad6.12e-0717


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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