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Coexpression cluster:C2765

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Full id: C2765_liver_Hepatocyte_mature_Nucleus_Anulus_adipose_Adipocyte



Phase1 CAGE Peaks

Hg19::chr4:100228979..100229001,-p@chr4:100228979..100229001
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Hg19::chr4:100232048..100232064,-p@chr4:100232048..100232064
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Hg19::chr4:100237205..100237224,-p@chr4:100237205..100237224
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Hg19::chr4:100242534..100242546,-p2@ADH1B


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
fat cell9.10e-2015
adipocyte of omentum tissue5.30e-073
Uber Anatomy
Ontology termp-valuen
adult organism2.87e-26114
intervertebral cartilage7.00e-105
symphysis7.00e-105
nonsynovial joint7.00e-105
fibrous joint7.00e-105
cartilaginous joint7.00e-105
developing mesenchymal condensation7.00e-105
pre-cartilage condensation7.00e-105
cartilaginous condensation7.00e-105
cartilage element7.00e-105
post-cranial axial skeletal system7.00e-105
vertebral column7.00e-105
intervertebral disk7.00e-105
intervertebral joint7.00e-105
articulation3.58e-088
skeletal joint3.58e-088
articular system3.58e-088
digestive system8.49e-08145
digestive tract8.49e-08145
primitive gut8.49e-08145
subdivision of digestive tract1.75e-07118
saliva-secreting gland3.08e-076
gland of oral region3.08e-076
gland of foregut3.08e-076
oral gland3.08e-076
oral cavity3.08e-076
endoderm-derived structure8.37e-07160
endoderm8.37e-07160
presumptive endoderm8.37e-07160


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.