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Coexpression cluster:C1791

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Full id: C1791_skin_lung_heart_trachea_left_throat_uterus



Phase1 CAGE Peaks

Hg19::chr17:67224798..67224809,-p7@ABCA10
Hg19::chr17:67224812..67224826,-p4@ABCA10
Hg19::chr17:67224835..67224846,-p5@ABCA10
Hg19::chr17:67224876..67224912,-p1@ABCA10
Hg19::chr17:67224950..67224970,-p2@ABCA10


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.34e-65115
neural tube4.69e-2357
neural rod4.69e-2357
future spinal cord4.69e-2357
neural keel4.69e-2357
regional part of brain1.10e-1859
anterior neural tube2.83e-1842
regional part of forebrain2.49e-1741
forebrain2.49e-1741
future forebrain2.49e-1741
neural plate1.04e-1686
presumptive neural plate1.04e-1686
anatomical conduit5.08e-16241
neurectoderm5.74e-1690
central nervous system2.60e-1582
anatomical cluster4.94e-15286
brain1.74e-1469
future brain1.74e-1469
gray matter4.92e-1434
brain grey matter4.92e-1434
telencephalon7.43e-1434
regional part of telencephalon2.50e-1333
multi-tissue structure3.69e-13347
regional part of nervous system7.95e-1394
nervous system7.95e-1394
cerebral hemisphere1.68e-1232
organ3.28e-12511
anterior region of body6.79e-12129
craniocervical region6.79e-12129
tube1.24e-11194
pre-chordal neural plate6.73e-1161
organism subdivision1.27e-10365
neocortex1.59e-1020
regional part of cerebral cortex2.02e-1022
head2.38e-10123
multi-cellular organism4.69e-10659
anatomical system2.01e-09625
epithelium2.17e-09309
anatomical group2.49e-09626
cell layer4.81e-09312
cerebral cortex1.43e-0825
pallium1.43e-0825
embryo1.54e-08612
embryonic structure3.35e-08605
developing anatomical structure3.35e-08605
ectoderm-derived structure4.46e-08169
ectoderm6.93e-08173
presumptive ectoderm6.93e-08173
germ layer7.59e-08604
embryonic tissue7.59e-08604
presumptive structure7.59e-08604
epiblast (generic)7.59e-08604
brainstem1.27e-078
nucleus of brain1.55e-079
basal ganglion1.55e-079
neural nucleus1.55e-079
nuclear complex of neuraxis1.55e-079
aggregate regional part of brain1.55e-079
collection of basal ganglia1.55e-079
cerebral subcortex1.55e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.