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Coexpression cluster:C363

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Full id: C363_Mallassezderived_Gingival_Keratinocyte_Mammary_Prostate_Small_Urothelial



Phase1 CAGE Peaks

Hg19::chr18:21452899..21452910,+p2@LAMA3
Hg19::chr18:21452964..21452993,+p1@LAMA3
Hg19::chr18:21461943..21461955,+p@chr18:21461943..21461955
+
Hg19::chr18:21464760..21464772,+p2@X77598
Hg19::chr18:21474288..21474320,-p@chr18:21474288..21474320
-
Hg19::chr18:21474914..21474939,+p@chr18:21474914..21474939
+
Hg19::chr18:21474947..21474966,+p@chr18:21474947..21474966
+
Hg19::chr18:21478695..21478707,+p9@LAMA3
Hg19::chr18:21478968..21478985,-p@chr18:21478968..21478985
-
Hg19::chr18:21478996..21479008,-p@chr18:21478996..21479008
-
Hg19::chr18:21479321..21479334,+p@chr18:21479321..21479334
+
Hg19::chr18:21479368..21479399,-p@chr18:21479368..21479399
-
Hg19::chr18:21479408..21479415,-p@chr18:21479408..21479415
-
Hg19::chr18:21481109..21481120,+p@chr18:21481109..21481120
+
Hg19::chr18:21481125..21481150,+p@chr18:21481125..21481150
+
Hg19::chr18:21481209..21481225,+p@chr18:21481209..21481225
+
Hg19::chr18:21483933..21483967,-p@chr18:21483933..21483967
-
Hg19::chr18:21483996..21484010,+p@chr18:21483996..21484010
+
Hg19::chr18:21484533..21484572,+p@chr18:21484533..21484572
+
Hg19::chr18:21484604..21484624,+p@chr18:21484604..21484624
+
Hg19::chr18:21485515..21485536,-p@chr18:21485515..21485536
-
Hg19::chr18:21485558..21485596,-p@chr18:21485558..21485596
-
Hg19::chr18:21487576..21487588,-p@chr18:21487576..21487588
-
Hg19::chr18:21487788..21487807,+p@chr18:21487788..21487807
+
Hg19::chr18:21487848..21487862,-p@chr18:21487848..21487862
-
Hg19::chr18:21494675..21494689,+p@chr18:21494675..21494689
+
Hg19::chr18:21500893..21500904,+p@chr18:21500893..21500904
+
Hg19::chr18:21508639..21508652,+p@chr18:21508639..21508652
+
Hg19::chr18:21529811..21529823,+p@chr18:21529811..21529823
+
Hg19::chr18:21531667..21531694,+p@chr18:21531667..21531694
+
Hg19::chr3:129513704..129513729,-p12@TMCC1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0045995regulation of embryonic development0.00988889675790024
GO:0005606laminin-1 complex0.00988889675790024
GO:0043256laminin complex0.00988889675790024
GO:0005605basal lamina0.0182777618173525
GO:0030334regulation of cell migration0.0182777618173525
GO:0030155regulation of cell adhesion0.0182777618173525
GO:0051270regulation of cell motility0.0182777618173525
GO:0040012regulation of locomotion0.0182777618173525
GO:0040011locomotion0.0182777618173525
GO:0005604basement membrane0.0182777618173525
GO:0044420extracellular matrix part0.0277102104427011
GO:0008544epidermis development0.0277102104427011
GO:0007398ectoderm development0.0277102104427011
GO:0016477cell migration0.0363450637728375
GO:0009790embryonic development0.0363450637728375
GO:0050793regulation of developmental process0.0363450637728375
GO:0009888tissue development0.0441633001453489
GO:0051674localization of cell0.0495626658089424
GO:0006928cell motility0.0495626658089424



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen
epithelial cell7.46e-20254
endo-epithelial cell9.24e-1943
endodermal cell2.94e-1259
epithelial cell of alimentary canal3.33e-0921
general ecto-epithelial cell1.99e-0713
respiratory epithelial cell2.98e-0713
Uber Anatomy
Ontology termp-valuen
endoderm-derived structure1.20e-13169
endoderm1.20e-13169
presumptive endoderm1.20e-13169
organ1.15e-12511
respiratory system1.84e-0972
anatomical system2.05e-09625
digestive system2.38e-09155
digestive tract2.38e-09155
primitive gut2.38e-09155
multi-cellular organism2.99e-09659
anatomical group3.24e-09626
anatomical space8.48e-09104
orifice1.54e-0835
reproductive structure2.68e-0859
reproductive system2.68e-0859
mixed endoderm/mesoderm-derived structure3.44e-08130
organ component layer4.50e-0857
renal system6.76e-0845
subdivision of digestive tract8.61e-08129
endodermal part of digestive tract8.61e-08129
urinary system structure1.37e-0744
extraembryonic membrane2.00e-0714
membranous layer2.00e-0714
embryo2.34e-07612
internal genitalia2.80e-0725
embryonic structure2.91e-07605
developing anatomical structure2.91e-07605
germ layer4.79e-07604
embryonic tissue4.79e-07604
presumptive structure4.79e-07604
epiblast (generic)4.79e-07604
reproductive organ8.34e-0748
organ part8.99e-07219
Disease
Ontology termp-valuen
carcinoma2.43e-12106
squamous cell carcinoma1.41e-0814
cell type cancer6.06e-07143


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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