Personal tools

Coexpression cluster:C566

From FANTOM5_SSTAR

Revision as of 14:55, 21 May 2012 by Autoedit (talk | contribs)
Jump to: navigation, search


Full id: C566_Pericytes_Renal_hepatic_Fibroblast_Endothelial_Hepatic_Lens



Phase1 CAGE Peaks

Hg19::chr13:110802350..110802403,-p3@COL4A1
Hg19::chr13:110802503..110802522,-p9@COL4A1
Hg19::chr13:110802740..110802769,-p2@COL4A1
Hg19::chr13:110804802..110804837,-p@chr13:110804802..110804837
-
Hg19::chr13:110829310..110829326,-p@chr13:110829310..110829326
-
Hg19::chr13:110829341..110829354,-p@chr13:110829341..110829354
-
Hg19::chr13:110839601..110839634,-p@chr13:110839601..110839634
-
Hg19::chr13:110853822..110853836,-p@chr13:110853822..110853836
-
Hg19::chr13:110861222..110861235,-p@chr13:110861222..110861235
-
Hg19::chr13:110864247..110864268,-p@chr13:110864247..110864268
-
Hg19::chr13:110959496..110959511,-p1@COL4A1
Hg19::chr13:110959598..110959611,+p2@COL4A2
Hg19::chr13:110959623..110959640,+p1@COL4A2
Hg19::chr13:111009846..111009888,-p@chr13:111009846..111009888
-
Hg19::chr13:111164370..111164403,+p@chr13:111164370..111164403
+
Hg19::chr13:111164549..111164576,+p@chr13:111164549..111164576
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005581collagen9.1276660944864e-05
GO:0005604basement membrane9.1276660944864e-05
GO:0005201extracellular matrix structural constituent0.00013724278986645
GO:0044420extracellular matrix part0.00013724278986645
GO:0006817phosphate transport0.00013724278986645
GO:0015698inorganic anion transport0.000379277449588247
GO:0006820anion transport0.000502106119333132
GO:0005578proteinaceous extracellular matrix0.000746924249734859
GO:0005587collagen type IV0.00127548516830642
GO:0030935sheet-forming collagen0.00137750370557821
GO:0044421extracellular region part0.00254125210080381
GO:0016525negative regulation of angiogenesis0.003251912687054
GO:0006811ion transport0.00483283573650064
GO:0045765regulation of angiogenesis0.0062286291620965
GO:0030198extracellular matrix organization and biogenesis0.00703642914021911
GO:0043062extracellular structure organization and biogenesis0.0120393189222703
GO:0001525angiogenesis0.0173898289872081
GO:0048514blood vessel morphogenesis0.0181053237656383
GO:0048646anatomical structure formation0.0181053237656383
GO:0001568blood vessel development0.0181053237656383
GO:0001944vasculature development0.0181053237656383
GO:0006810transport0.0250029879971245
GO:0051234establishment of localization0.0251161640147931
GO:0051179localization0.0282668149955082
GO:0009887organ morphogenesis0.0330695538606439



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
vasculature3.01e-1979
vascular system3.01e-1979
epithelial tube5.61e-18118
circulatory system1.32e-16113
splanchnic layer of lateral plate mesoderm1.83e-1684
cardiovascular system6.27e-16110
vessel1.96e-1569
trunk mesenchyme4.12e-14143
multi-cellular organism7.17e-14659
anatomical cluster9.03e-14286
cell layer4.78e-13312
blood vessel1.95e-1260
epithelial tube open at both ends1.95e-1260
blood vasculature1.95e-1260
vascular cord1.95e-1260
organism subdivision2.53e-12365
epithelium2.69e-12309
anatomical conduit3.38e-12241
trunk1.85e-11216
multi-tissue structure3.14e-11347
unilaminar epithelium6.58e-11138
muscle tissue1.29e-1063
musculature1.29e-1063
musculature of body1.29e-1063
compound organ1.48e-1069
skeletal muscle tissue2.72e-1061
striated muscle tissue2.72e-1061
myotome2.72e-1061
anatomical system7.20e-10625
anatomical group1.30e-09626
urogenital ridge3.95e-0920
tube4.03e-09194
mesenchyme8.19e-09238
entire embryonic mesenchyme8.19e-09238
somite8.95e-0983
paraxial mesoderm8.95e-0983
presomitic mesoderm8.95e-0983
presumptive segmental plate8.95e-0983
trunk paraxial mesoderm8.95e-0983
presumptive paraxial mesoderm8.95e-0983
dermomyotome1.28e-0870
body cavity precursor1.75e-0863
mesonephros2.78e-0818
pronephros2.78e-0818
nephrogenic cord2.78e-0818
pronephric mesoderm2.78e-0818
rostral part of nephrogenic cord2.78e-0818
presumptive pronephric mesoderm2.78e-0818
multilaminar epithelium3.17e-0882
excretory tube3.28e-0817
mesonephric epithelium3.28e-0817
mesonephric tubule3.28e-0817
nephric duct3.28e-0817
kidney epithelium3.28e-0817
renal duct3.28e-0817
mesonephric duct3.28e-0817
pronephric duct3.28e-0817
nephron epithelium3.75e-0816
nephron3.75e-0816
uriniferous tubule3.75e-0816
metanephric mesenchyme3.75e-0816
nephrogenic mesenchyme3.75e-0816
parenchyma4.66e-0817
artery5.20e-0842
arterial blood vessel5.20e-0842
arterial system5.20e-0842
intraembryonic coelom6.84e-0821
intermediate mesoderm9.19e-0837
anatomical cavity3.92e-0770
abdominal segment of trunk6.33e-0761
abdomen6.33e-0761
primary circulatory organ9.48e-0727


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.