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MCL coexpression mm9:321

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:62486608..62486619,-p2@Hnrnph3
Mm9::chr11:50641183..50641244,-p1@Zfp354c
Mm9::chr14:22319053..22319105,+p2@Myst4
Mm9::chr16:48994044..48994062,-p1@Dzip3
Mm9::chr18:65740410..65740452,+p@chr18:65740410..65740452
+
Mm9::chr1:137327004..137327065,-p1@Ipo9
Mm9::chr2:121097091..121097133,-p1@Trp53bp1
Mm9::chr2:13995774..13995818,+p2@Stam
Mm9::chr2:165213745..165213815,-p1@Zfp334
Mm9::chr3:129763728..129763744,-p4@Sec24b
Mm9::chr4:137772539..137772565,+p1@Hp1bp3
Mm9::chr4:155043228..155043272,-p2@Mib2
Mm9::chr4:54960870..54960926,+p1@Zfp462
Mm9::chr4:83132361..83132382,-p2@Psip1
Mm9::chr5:111308807..111308861,+p1@Ttc28
Mm9::chr5:31754831..31754876,+p1@Zfp512
Mm9::chr5:53225284..53225351,+p2@Anapc4
Mm9::chr7:17199897..17199955,-p1@Grlf1
Mm9::chr7:30568977..30569047,+p1@Zfp30
Mm9::chr8:108939219..108939296,+p1@Zfp90
Mm9::chr8:86707764..86707815,-p@chr8:86707764..86707815
-
Mm9::chr9:45714452..45714520,-p1@Rnf214
Mm9::chrX:143988594..143988630,-p1@Lrch2
Mm9::chrX:148235416..148235455,+p2@Huwe1
Mm9::chrX:148235556..148235626,+p5@Huwe1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0043283biopolymer metabolic process0.00794587097948635
GO:0003677DNA binding0.00794587097948635
GO:0043170macromolecule metabolic process0.0113426159567994
GO:0005634nucleus0.0113426159567994
GO:0003676nucleic acid binding0.0113426159567994
GO:0006355regulation of transcription, DNA-dependent0.0116253998330533
GO:0006351transcription, DNA-dependent0.0116253998330533
GO:0032774RNA biosynthetic process0.0116253998330533
GO:0008270zinc ion binding0.0116253998330533
GO:0045449regulation of transcription0.0121275033569461
GO:0019219regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0125967280283161
GO:0006350transcription0.0126131748376515
GO:0010468regulation of gene expression0.0145568400482656
GO:0031323regulation of cellular metabolic process0.0176996880778582
GO:0006512ubiquitin cycle0.0189891975018616
GO:0019222regulation of metabolic process0.0196114607507608
GO:0044238primary metabolic process0.0196114607507608
GO:0044237cellular metabolic process0.0196114607507608
GO:0016070RNA metabolic process0.0197265385463275
GO:0046914transition metal ion binding0.0222689625102905
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0234264727644384
GO:0051100negative regulation of binding0.0234264727644384
GO:0043392negative regulation of DNA binding0.0234264727644384
GO:0004406H3/H4 histone acetyltransferase activity0.0323117080144102
GO:0044427chromosomal part0.0385349237162417
GO:0065003macromolecular complex assembly0.0407551671595038
GO:0006334nucleosome assembly0.0407551671595038
GO:0010467gene expression0.0407551671595038
GO:0016874ligase activity0.0407551671595038
GO:0004842ubiquitin-protein ligase activity0.0407551671595038
GO:0000786nucleosome0.0407551671595038
GO:0006610ribosomal protein import into nucleus0.0407551671595038
GO:0008639small protein conjugating enzyme activity0.0413391853083521
GO:0031497chromatin assembly0.0416704877530539
GO:0005694chromosome0.0437425671811541
GO:0043231intracellular membrane-bound organelle0.0437425671811541
GO:0019787small conjugating protein ligase activity0.0437425671811541
GO:0043227membrane-bound organelle0.0437425671811541
GO:0022607cellular component assembly0.0437425671811541
GO:0033036macromolecule localization0.0437425671811541
GO:0065004protein-DNA complex assembly0.0437425671811541
GO:0008536Ran GTPase binding0.0437425671811541
GO:0016881acid-amino acid ligase activity0.0467068866387382
GO:0050821protein stabilization0.0467068866387382
GO:0042393histone binding0.0467068866387382
GO:0006333chromatin assembly or disassembly0.0467102769164932
GO:0043687post-translational protein modification0.0483164904506294
GO:0031647regulation of protein stability0.0483164904506294
GO:0016573histone acetylation0.0483164904506294



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neurectoderm3.81e-2164
neural plate3.81e-2164
presumptive neural plate3.81e-2164
central nervous system5.23e-2173
nervous system5.16e-2075
ectoderm-derived structure5.40e-2095
ectoderm5.40e-2095
presumptive ectoderm5.40e-2095
ecto-epithelium1.05e-1873
structure with developmental contribution from neural crest6.84e-1892
pre-chordal neural plate2.58e-1749
regional part of nervous system3.94e-1754
neural tube2.45e-1652
neural rod2.45e-1652
future spinal cord2.45e-1652
neural keel2.45e-1652
brain3.67e-1447
future brain3.67e-1447
anterior neural tube7.35e-1440
regional part of brain1.36e-1346
regional part of forebrain1.91e-1339
forebrain1.91e-1339
future forebrain1.91e-1339
gray matter6.95e-1334
brain grey matter1.78e-1029
regional part of telencephalon1.78e-1029
telencephalon1.78e-1029
multi-cellular organism4.95e-09333
embryo2.37e-08320
cerebral cortex4.66e-0721
cerebral hemisphere4.66e-0721
pallium4.66e-0721


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.17.41658
MA0004.10.118549
MA0006.12.48471
MA0007.10.356106
MA0009.11.11793
MA0014.15.27522
MA0017.10.190692
MA0019.10.290797
MA0024.10.401898
MA0025.10.645374
MA0027.12.02409
MA0028.10.691856
MA0029.10.383872
MA0030.10.389298
MA0031.10.360121
MA0038.10.209603
MA0040.10.449452
MA0041.10.272875
MA0042.10.255859
MA0043.10.522621
MA0046.10.469568
MA0048.11.56087
MA0050.10.141024
MA0051.10.617538
MA0052.10.456356
MA0055.11.00469
MA0056.10
MA0057.12.17998
MA0058.10.24722
MA0059.10.0759876
MA0060.10.215905
MA0061.10.0263971
MA0063.10
MA0066.10.20204
MA0067.10.748059
MA0068.11.1508
MA0069.10.456647
MA0070.10.448343
MA0071.10.140522
MA0072.10.44111
MA0073.14.0252
MA0074.10.178027
MA0076.10.808369
MA0077.10.422739
MA0078.10.239324
MA0081.10.611511
MA0083.10.521922
MA0084.11.0607
MA0087.10.484199
MA0088.10.759099
MA0089.10
MA0090.10.32897
MA0091.10.125983
MA0092.10.100239
MA0093.10.181765
MA0095.10
MA0098.10
MA0100.10.508591
MA0101.10.274567
MA0103.10.203213
MA0105.10.223957
MA0106.10.244965
MA0107.10.0529506
MA0108.20.308463
MA0109.10
MA0111.10.708981
MA0113.10.224694
MA0114.10.109084
MA0115.10.525089
MA0116.10.367847
MA0117.10.496768
MA0119.10.275337
MA0122.10.514153
MA0124.10.698593
MA0125.10.630583
MA0130.10
MA0131.10.287321
MA0132.10
MA0133.10
MA0135.10.554905
MA0136.10.191208
MA0139.11.5573
MA0140.10.170444
MA0141.10.0633664
MA0142.10.34839
MA0143.10.236381
MA0144.10.270735
MA0145.10.414538
MA0146.12.36732
MA0147.11.68084
MA0148.10.127756
MA0149.10.281823
MA0062.20.926673
MA0035.20.173482
MA0039.23.5742
MA0138.20.769269
MA0002.20.169578
MA0137.20.062153
MA0104.21.69822
MA0047.20.209072
MA0112.21.09552
MA0065.20.264546
MA0150.10.355945
MA0151.10
MA0152.10.209147
MA0153.10.569763
MA0154.11.90914
MA0155.12.73477
MA0156.10.464199
MA0157.10.322822
MA0158.10
MA0159.11.29831
MA0160.10.129493
MA0161.10
MA0162.15.56595
MA0163.18.77013
MA0164.10.191451
MA0080.20.197063
MA0018.20.197998
MA0099.20.276491
MA0079.219.7748
MA0102.21.11159
MA0258.10.240529
MA0259.10.813577
MA0442.10