MCL coexpression mm9:418

Phase1 CAGE Peaks

	Short description
Mm9::chr10:68561303..68561307,-	p@chr10:68561303..68561307 -
Mm9::chr10:68587830..68587845,-	p@chr10:68587830..68587845 -
Mm9::chr10:77816382..77816390,-	p@chr10:77816382..77816390 -
Mm9::chr10:98152696..98152728,-	p@chr10:98152696..98152728 -
Mm9::chr12:70870720..70870729,-	p@chr12:70870720..70870729 -
Mm9::chr14:60145568..60145589,+	p@chr14:60145568..60145589 +
Mm9::chr18:84849979..84849983,-	p@chr18:84849979..84849983 -
Mm9::chr1:189431154..189431187,+	p@chr1:189431154..189431187 +
Mm9::chr1:92460728..92460770,+	p@chr1:92460728..92460770 +
Mm9::chr2:62250357..62250366,-	p11@Dpp4
Mm9::chr3:128919820..128919855,-	p@chr3:128919820..128919855 -
Mm9::chr8:11282081..11282090,-	p@chr8:11282081..11282090 -
Mm9::chr8:113605570..113605579,-	p8@Clec18a
Mm9::chr8:113605732..113605743,-	p7@Clec18a
Mm9::chr8:113605755..113605771,-	p4@Clec18a
Mm9::chr8:62931423..62931425,-	p@chr8:62931423..62931425 -
Mm9::chr8:62982021..62982030,-	p1@ENSMUST00000093494
Mm9::chr9:25015356..25015369,-	p@chr9:25015356..25015369 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008238	exopeptidase activity	0.00120704627445353
GO:0042315	cytosol nonspecific dipeptidase activity	0.00504012927892669
GO:0004287	prolyl oligopeptidase activity	0.00671980417354201
GO:0046581	intercellular canaliculus	0.00673351956246092
GO:0004274	dipeptidyl-peptidase IV activity	0.00673351956246092
GO:0006508	proteolysis	0.00673351956246092
GO:0008239	dipeptidyl-peptidase activity	0.00673351956246092
GO:0016806	dipeptidyl-peptidase and tripeptidyl-peptidase activity	0.00673351956246092
GO:0008233	peptidase activity	0.00673351956246092
GO:0016805	dipeptidase activity	0.00705386134082785
GO:0004177	aminopeptidase activity	0.016936906999236
GO:0004180	carboxypeptidase activity	0.0176211220623309
GO:0016787	hydrolase activity	0.0438332217438319
GO:0005911	intercellular junction	0.0462115008870231
GO:0004252	serine-type endopeptidase activity	0.0462115008870231
GO:0044267	cellular protein metabolic process	0.0462115008870231
GO:0008237	metallopeptidase activity	0.0462115008870231
GO:0044260	cellular macromolecule metabolic process	0.0462115008870231
GO:0046983	protein dimerization activity	0.0462115008870231
GO:0008236	serine-type peptidase activity	0.0462115008870231
GO:0017171	serine hydrolase activity	0.0462115008870231
GO:0019538	protein metabolic process	0.0462115008870231

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
kidney	6.77e-25	14
kidney mesenchyme	6.77e-25	14
upper urinary tract	6.77e-25	14
kidney rudiment	6.77e-25	14
kidney field	6.77e-25	14
urinary system structure	4.52e-19	18
renal system	5.35e-18	19
cavitated compound organ	3.72e-16	21
compound organ	3.47e-07	43

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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