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MCL coexpression mm9:3349

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Phase1 CAGE Peaks

 Short description
Mm9::chr2:38142694..38142715,-p2@Dennd1a
Mm9::chr2:38142729..38142745,-p3@Dennd1a
Mm9::chr3:135148569..135148632,+p1@Manba


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004567beta-mannosidase activity0.00690297485344875
GO:0048488synaptic vesicle endocytosis0.0172508185679887
GO:0006516glycoprotein catabolic process0.0172508185679887
GO:0017124SH3 domain binding0.0172508185679887
GO:0015923mannosidase activity0.0172508185679887
GO:0030665clathrin coated vesicle membrane0.0172508185679887
GO:0048489synaptic vesicle transport0.0224193037463458
GO:0030662coated vesicle membrane0.0224193037463458
GO:0030659cytoplasmic vesicle membrane0.0280618538186314
GO:0030425dendrite0.0280618538186314
GO:0044433cytoplasmic vesicle part0.0280618538186314
GO:0019904protein domain specific binding0.0280618538186314
GO:0012506vesicle membrane0.0280618538186314
GO:0043025cell soma0.0280618538186314
GO:0030136clathrin-coated vesicle0.0339865740550138
GO:0030135coated vesicle0.0352437618835035
GO:0004553hydrolase activity, hydrolyzing O-glycosyl compounds0.0352437618835035
GO:0009100glycoprotein metabolic process0.0374829962895571
GO:0016798hydrolase activity, acting on glycosyl bonds0.0391229485738048
GO:0043005neuron projection0.0399111231992233
GO:0010324membrane invagination0.0486697011754536
GO:0006897endocytosis0.0486697011754536
GO:0005764lysosome0.0486697011754536
GO:0000323lytic vacuole0.0486697011754536
GO:0016023cytoplasmic membrane-bound vesicle0.0493369173761718
GO:0005773vacuole0.0493369173761718
GO:0031988membrane-bound vesicle0.0493369173761718



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
endoderm-derived structure3.98e-09118
endoderm3.98e-09118
presumptive endoderm3.98e-09118
digestive tract diverticulum9.04e-0923
sac9.04e-0923
trunk region element1.14e-0879
subdivision of digestive tract1.23e-08114
liver1.39e-0822
epithelial sac1.39e-0822
digestive gland1.39e-0822
epithelium of foregut-midgut junction1.39e-0822
anatomical boundary1.39e-0822
hepatobiliary system1.39e-0822
foregut-midgut junction1.39e-0822
hepatic diverticulum1.39e-0822
liver primordium1.39e-0822
septum transversum1.39e-0822
liver bud1.39e-0822
endo-epithelium1.43e-0869
digestive system2.51e-08116
digestive tract2.51e-08116
primitive gut2.51e-08116
exocrine gland4.44e-0825
exocrine system4.44e-0825
subdivision of trunk1.48e-0766
foregut1.53e-0780
abdomen element2.57e-0749
abdominal segment element2.57e-0749
abdominal segment of trunk2.57e-0749
abdomen2.57e-0749
trunk4.02e-0790


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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