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MCL coexpression mm9:90

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:31165749..31165773,-p3@Tpd52l1
Mm9::chr10:40792085..40792096,-p1@Gpr6
Mm9::chr10:40792098..40792114,-p2@Gpr6
Mm9::chr10:74523630..74523646,+p4@Bcr
Mm9::chr10:74787674..74787682,+p@chr10:74787674..74787682
+
Mm9::chr10:74787686..74787708,+p@chr10:74787686..74787708
+
Mm9::chr10:74787713..74787724,+p@chr10:74787713..74787724
+
Mm9::chr10:74787727..74787734,+p@chr10:74787727..74787734
+
Mm9::chr10:80460866..80460877,-p7@Gng7
Mm9::chr10:80460891..80460908,-p6@Gng7
Mm9::chr10:80460919..80460937,-p5@Gng7
Mm9::chr10:80477623..80477646,-p1@Gng7
Mm9::chr10:80477647..80477682,-p2@Gng7
Mm9::chr10:80945078..80945098,-p@chr10:80945078..80945098
-
Mm9::chr10:84380448..84380461,+p6@Ric8b
Mm9::chr11:100054413..100054417,-p@chr11:100054413..100054417
-
Mm9::chr11:100621055..100621068,-p1@Kcnh4
Mm9::chr11:109159386..109159393,-p5@Rgs9
Mm9::chr11:67384717..67384769,+p@chr11:67384717..67384769
+
Mm9::chr11:77651507..77651511,+p22@Myo18a
Mm9::chr11:98209742..98209748,+p12@Ppp1r1b
Mm9::chr11:98209780..98209787,+p11@Ppp1r1b
Mm9::chr12:106692245..106692257,+p3@D430019H16Rik
Mm9::chr12:106714111..106714121,+p@chr12:106714111..106714121
+
Mm9::chr12:38607287..38607315,+p5@Dgkb
Mm9::chr12:38607393..38607465,+p2@Dgkb
Mm9::chr12:41520846..41520858,+p@chr12:41520846..41520858
+
Mm9::chr12:86039719..86039769,-p2@Tmem90a
Mm9::chr13:42776156..42776172,+p1@Phactr1
Mm9::chr13:42776254..42776263,+p15@Phactr1
Mm9::chr13:42895175..42895186,+p@chr13:42895175..42895186
+
Mm9::chr13:54150457..54150487,-p@chr13:54150457..54150487
-
Mm9::chr13:54151019..54151049,-p1@Drd1a
Mm9::chr14:28689579..28689606,+p@chr14:28689579..28689606
+
Mm9::chr14:28689707..28689727,+p@chr14:28689707..28689727
+
Mm9::chr14:30245460..30245462,-p@chr14:30245460..30245462
-
Mm9::chr15:103333382..103333461,+p1@Pde1b
Mm9::chr15:103333469..103333476,+p11@Pde1b
Mm9::chr15:103333498..103333519,+p4@Pde1b
Mm9::chr15:103333681..103333690,+p7@Pde1b
Mm9::chr15:103333692..103333719,+p3@Pde1b
Mm9::chr15:78258877..78258887,+p7@Kctd17
Mm9::chr15:78541204..78541223,-p@chr15:78541204..78541223
-
Mm9::chr16:11778541..11778558,+p@chr16:11778541..11778558
+
Mm9::chr16:35154956..35155015,+p1@Adcy5
Mm9::chr16:35155616..35155631,+p2@Adcy5
Mm9::chr16:35156592..35156634,+p@chr16:35156592..35156634
+
Mm9::chr16:57121568..57121599,+p6@Tomm70a
Mm9::chr17:56511861..56511871,+p2@Kdm4b
Mm9::chr17:8994607..8994616,+p13@Pde10a
Mm9::chr17:8994633..8994653,+p1@Pde10a
Mm9::chr18:4590729..4590757,+p@chr18:4590729..4590757
+
Mm9::chr18:64424692..64424721,+p@chr18:64424692..64424721
+
Mm9::chr18:64424726..64424741,+p@chr18:64424726..64424741
+
Mm9::chr18:64424996..64425019,+p@chr18:64424996..64425019
+
Mm9::chr18:67293132..67293150,+p7@Gnal
Mm9::chr18:67293152..67293189,+p2@Gnal
Mm9::chr18:67293201..67293239,+p3@Gnal
Mm9::chr18:74225311..74225335,-p3@Mapk4
Mm9::chr18:74867662..74867697,+p@chr18:74867662..74867697
+
Mm9::chr18:85241138..85241157,+p@chr18:85241138..85241157
+
Mm9::chr18:85241159..85241166,+p@chr18:85241159..85241166
+
Mm9::chr18:85241225..85241251,+p@chr18:85241225..85241251
+
Mm9::chr19:10532035..10532047,-p1@Lrrc10b
Mm9::chr19:6400523..6400559,+p4@Rasgrp2
Mm9::chr1:155512412..155512455,+p3@Rgs8
Mm9::chr1:156573790..156573798,-p@chr1:156573790..156573798
-
Mm9::chr1:162508024..162508035,-p1@Gpr52
Mm9::chr2:110680178..110680197,-p@chr2:110680178..110680197
-
Mm9::chr2:110680212..110680219,-p@chr2:110680212..110680219
-
Mm9::chr2:110680273..110680311,-p@chr2:110680273..110680311
-
Mm9::chr2:113057183..113057196,-p2@Ryr3
Mm9::chr2:113057209..113057251,-p1@Ryr3
Mm9::chr2:115890294..115890334,-p9@Meis2
Mm9::chr2:71819043..71819052,+p12@Rapgef4
Mm9::chr2:91816465..91816503,-p5@Dgkz
Mm9::chr3:115955655..115955678,-p@chr3:115955655..115955678
-
Mm9::chr3:115955687..115955723,-p@chr3:115955687..115955723
-
Mm9::chr3:115956329..115956351,-p2@Gpr88
Mm9::chr3:115956385..115956401,-p1@Gpr88
Mm9::chr3:115956417..115956424,-p3@Gpr88
Mm9::chr3:136333484..136333491,+p14@Ppp3ca
Mm9::chr3:64912890..64912909,+p13@Kcnab1
Mm9::chr3:64912918..64912959,+p3@Kcnab1
Mm9::chr3:64912965..64913011,+p2@Kcnab1
Mm9::chr3:64913191..64913209,+p5@Kcnab1
Mm9::chr4:126850464..126850477,+p5@Dlgap3
Mm9::chr4:128798825..128798844,-p5@Hpca
Mm9::chr4:128798845..128798868,-p4@Hpca
Mm9::chr4:4065921..4065945,-p1@Penk
Mm9::chr4:42935125..42935132,+p7@N28178
Mm9::chr5:130924706..130924726,+p2@Caln1
Mm9::chr5:35332032..35332052,+p11@Rgs12
Mm9::chr5:36157005..36157020,+p6@Ablim2
Mm9::chr5:36157024..36157049,+p5@Ablim2
Mm9::chr5:36157073..36157102,+p2@Ablim2
Mm9::chr5:36157104..36157131,+p3@Ablim2
Mm9::chr5:72049330..72049354,-p4@Gabra4
Mm9::chr6:124820539..124820547,-p4@Cd4
Mm9::chr6:125661510..125661529,+p5@Ano2
Mm9::chr6:4853350..4853367,+p6@Ppp1r9a
Mm9::chr6:6813769..6813781,+p8@Dlx6
Mm9::chr6:7505053..7505067,+p1@Tac1
Mm9::chr6:99471722..99471738,-p@chr6:99471722..99471738
-
Mm9::chr7:108570205..108570240,+p2@Pde2a
Mm9::chr7:132326044..132326063,+p@chr7:132326044..132326063
+
Mm9::chr7:134006144..134006198,+p3@Hirip3
Mm9::chr7:139508746..139508812,-p3@Chst15
Mm9::chr7:16506016..16506041,-p@chr7:16506016..16506041
-
Mm9::chr7:16506127..16506140,-p@chr7:16506127..16506140
-
Mm9::chr7:19904374..19904392,+p@chr7:19904374..19904392
+
Mm9::chr7:54346748..54346759,-p7@Ptpn5
Mm9::chr7:54346781..54346788,-p15@Ptpn5
Mm9::chr7:54346794..54346803,-p13@Ptpn5
Mm9::chr7:54347084..54347095,-p17@Ptpn5
Mm9::chr8:121618902..121618932,+p@chr8:121618902..121618932
+
Mm9::chr8:25695822..25695846,-p@chr8:25695822..25695846
-
Mm9::chr8:77737224..77737233,+p@chr8:77737224..77737233
+
Mm9::chr8:77737255..77737268,+p@chr8:77737255..77737268
+
Mm9::chr8:77737329..77737360,+p1@Rasd2
Mm9::chr8:77737381..77737391,+p3@Rasd2
Mm9::chr9:104490381..104490405,+p@chr9:104490381..104490405
+
Mm9::chr9:107408215..107408223,+p@chr9:107408215..107408223
+
Mm9::chr9:112088433..112088440,-p55@Arpp21
Mm9::chr9:112088443..112088459,-p20@Arpp21
Mm9::chr9:112088460..112088471,-p31@Arpp21
Mm9::chr9:112090325..112090366,-p5@Arpp21
Mm9::chr9:112090379..112090382,-p41@Arpp21
Mm9::chr9:112090402..112090442,-p2@Arpp21
Mm9::chr9:44946379..44946388,+p20@Scn4b
Mm9::chr9:44946397..44946404,+p17@Scn4b
Mm9::chr9:44946623..44946632,+p8@Scn4b
Mm9::chr9:44946633..44946644,+p9@Scn4b
Mm9::chr9:44946659..44946677,+p3@Scn4b
Mm9::chr9:44946683..44946696,+p5@Scn4b
Mm9::chr9:44946699..44946714,+p2@Scn4b
Mm9::chr9:49148488..49148491,+p3@Drd2
Mm9::chr9:74899949..74899960,+p9@Arpp19
Mm9::chr9:75065277..75065290,+p@chr9:75065277..75065290
+
Mm9::chr9:75162042..75162072,+p2@Gnb5
Mm9::chr9:81525536..81525555,+p1@D430036J16Rik


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0019932second-messenger-mediated signaling1.67987448129523e-06
GO:0030695GTPase regulator activity3.73479831947888e-06
GO:0007212dopamine receptor signaling pathway4.53203076081549e-05
GO:0007154cell communication9.91948112958375e-05
GO:0007191dopamine receptor, adenylate cyclase activating pathway9.91948112958375e-05
GO:0019933cAMP-mediated signaling9.91948112958375e-05
GO:0019935cyclic-nucleotide-mediated signaling0.000108706869078756
GO:0007200G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)0.000148332225505885
GO:0007165signal transduction0.000285247603552889
GO:0048015phosphoinositide-mediated signaling0.000570405013893217
GO:0007188G-protein signaling, coupled to cAMP nucleotide second messenger0.000861503214965366
GO:0007242intracellular signaling cascade0.000861503214965366
GO:0007187G-protein signaling, coupled to cyclic nucleotide second messenger0.000861503214965366
GO:0021826substrate-independent telencephalic tangential migration0.000861503214965366
GO:0021853cerebral cortex GABAergic interneuron migration0.000861503214965366
GO:0021892cerebral cortex GABAergic interneuron differentiation0.000861503214965366
GO:0021843substrate-independent telencephalic tangential interneuron migration0.000861503214965366
GO:0021894cerebral cortex GABAergic interneuron development0.000861503214965366
GO:0007195dopamine receptor, adenylate cyclase inhibiting pathway0.000861503214965366
GO:0021830interneuron migration from the subpallium to the cortex0.000861503214965366
GO:0007626locomotory behavior0.000861503214965366
GO:0005085guanyl-nucleotide exchange factor activity0.000861503214965366
GO:0007610behavior0.000984225140601695
GO:0007632visual behavior0.000990098977124497
GO:0008542visual learning0.000990098977124497
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity0.00123283964400915
GO:0014821phasic smooth muscle contraction0.00123283964400915
GO:0030432peristalsis0.00123283964400915
GO:0060158dopamine receptor, phospholipase C activating pathway0.00123283964400915
GO:0004112cyclic-nucleotide phosphodiesterase activity0.00138160435598277
GO:0008599protein phosphatase type 1 regulator activity0.00174930254044207
GO:0060134prepulse inhibition0.00174930254044207
GO:0035240dopamine binding0.00174930254044207
GO:0004952dopamine receptor activity0.00174930254044207
GO:0019888protein phosphatase regulator activity0.00223150747272338
GO:0005834heterotrimeric G-protein complex0.00228329043281991
GO:0022029telencephalon cell migration0.00228329043281991
GO:0021885forebrain cell migration0.00228329043281991
GO:0007625grooming behavior0.00228329043281991
GO:0019208phosphatase regulator activity0.00249826337560556
GO:0007189G-protein signaling, adenylate cyclase activating pathway0.00249826337560556
GO:0007186G-protein coupled receptor protein signaling pathway0.00259331152330534
GO:0032102negative regulation of response to external stimulus0.00282808162663419
GO:0048585negative regulation of response to stimulus0.00282808162663419
GO:0001975response to amphetamine0.00433724391032152
GO:0021895cerebral cortex neuron differentiation0.00433724391032152
GO:0007617mating behavior0.00433724391032152
GO:0014075response to amine stimulus0.00433724391032152
GO:0032101regulation of response to external stimulus0.00433724391032152
GO:0050905neuromuscular process0.00489588316091451
GO:0007267cell-cell signaling0.00489588316091451
GO:0009966regulation of signal transduction0.00528640081502322
GO:0007612learning0.00528640081502322
GO:0019897extrinsic to plasma membrane0.0055083936311603
GO:0007190adenylate cyclase activation0.00656710072450938
GO:0004143diacylglycerol kinase activity0.00656710072450938
GO:0007193G-protein signaling, adenylate cyclase inhibiting pathway0.00656710072450938
GO:0001964startle response0.00656710072450938
GO:0007205protein kinase C activation0.00656710072450938
GO:0043085positive regulation of catalytic activity0.00714147858819942
GO:0051349positive regulation of lyase activity0.00714147858819942
GO:0045762positive regulation of adenylate cyclase activity0.00714147858819942
GO:0007618mating0.00714147858819942
GO:0031281positive regulation of cyclase activity0.00714147858819942
GO:0019098reproductive behavior0.00818829458176325
GO:0008081phosphoric diester hydrolase activity0.00974027484728955
GO:0005096GTPase activator activity0.0101340227563366
GO:0004864protein phosphatase inhibitor activity0.0101340227563366
GO:0045761regulation of adenylate cyclase activity0.0101340227563366
GO:0007611learning and/or memory0.0104724243175849
GO:0019898extrinsic to membrane0.0107721990982401
GO:0051339regulation of lyase activity0.012167552153248
GO:0031279regulation of cyclase activity0.012167552153248
GO:0009416response to light stimulus0.012169198284267
GO:0019212phosphatase inhibitor activity0.0132118061133011
GO:0042578phosphoric ester hydrolase activity0.013259024008737
GO:0051969regulation of transmission of nerve impulse0.0139106271670615
GO:0050804regulation of synaptic transmission0.0139106271670615
GO:0042417dopamine metabolic process0.0139106271670615
GO:0021954central nervous system neuron development0.0151545317852683
GO:0006936muscle contraction0.0158467089245332
GO:0003012muscle system process0.0158467089245332
GO:0007628adult walking behavior0.0158467089245332
GO:0051705behavioral interaction between organisms0.0158467089245332
GO:0021537telencephalon development0.0171199034859252
GO:0042165neurotransmitter binding0.0177117552055894
GO:0030594neurotransmitter receptor activity0.0177117552055894
GO:0021953central nervous system neuron differentiation0.017971629017873
GO:0015629actin cytoskeleton0.017971629017873
GO:0007268synaptic transmission0.017971629017873
GO:0009968negative regulation of signal transduction0.0180543782209528
GO:0033555multicellular organismal response to stress0.0186861691962858
GO:0009314response to radiation0.0193946091897893
GO:0006939smooth muscle contraction0.0194382049830469
GO:0031644regulation of neurological process0.0194382049830469
GO:0008047enzyme activator activity0.0194382049830469
GO:0048521negative regulation of behavior0.0194382049830469
GO:0051580regulation of neurotransmitter uptake0.0194382049830469
GO:0051586positive regulation of dopamine uptake0.0194382049830469
GO:0051940regulation of catecholamine uptake during transmission of nerve impulse0.0194382049830469
GO:0051588regulation of neurotransmitter transport0.0194382049830469
GO:0007621negative regulation of female receptivity0.0194382049830469
GO:0051590positive regulation of neurotransmitter transport0.0194382049830469
GO:0001670dopamine D2 receptor activity0.0194382049830469
GO:0051944positive regulation of catecholamine uptake during transmission of nerve impulse0.0194382049830469
GO:0051584regulation of dopamine uptake0.0194382049830469
GO:0001590dopamine D1 receptor activity0.0194382049830469
GO:0051582positive regulation of neurotransmitter uptake0.0194382049830469
GO:0030072peptide hormone secretion0.0197621429793617
GO:0007166cell surface receptor linked signal transduction0.019762629081123
GO:0006584catecholamine metabolic process0.0201087890220663
GO:0002790peptide secretion0.0201087890220663
GO:0018958phenol metabolic process0.0201087890220663
GO:0010033response to organic substance0.0201087890220663
GO:0005216ion channel activity0.0201087890220663
GO:0042493response to drug0.0211086688206527
GO:0032147activation of protein kinase activity0.0211086688206527
GO:0022838substrate specific channel activity0.022138635278208
GO:0006811ion transport0.0223440219917123
GO:0005516calmodulin binding0.0223440219917123
GO:0019226transmission of nerve impulse0.0245225117029149
GO:0007631feeding behavior0.0259143200223233
GO:0022803passive transmembrane transporter activity0.0259775108574798
GO:0015267channel activity0.0259775108574798
GO:0043005neuron projection0.026894284982276
GO:0042133neurotransmitter metabolic process0.0295258541562641
GO:0015833peptide transport0.0295258541562641
GO:0048755branching morphogenesis of a nerve0.0295258541562641
GO:0060181female receptivity0.0295258541562641
GO:0051967negative regulation of synaptic transmission, glutamatergic0.0295258541562641
GO:0045924regulation of female receptivity0.0295258541562641
GO:0060180female mating behavior0.0295258541562641
GO:0050805negative regulation of synaptic transmission0.0295258541562641
GO:0050795regulation of behavior0.0295258541562641
GO:0030314junctional membrane complex0.0295258541562641
GO:0030147natriuresis0.0295258541562641
GO:0007168receptor guanylyl cyclase signaling pathway0.0295258541562641
GO:0032922circadian regulation of gene expression0.0295258541562641
GO:0001973adenosine receptor signaling pathway0.0295258541562641
GO:0051970negative regulation of transmission of nerve impulse0.0295258541562641
GO:0051966regulation of synaptic transmission, glutamatergic0.0295258541562641
GO:0001588dopamine D1 receptor-like receptor activity0.0295258541562641
GO:0046879hormone secretion0.0318995508358186
GO:0008344adult locomotory behavior0.0332004339441862
GO:0008227amine receptor activity0.0345159122737346
GO:0048583regulation of response to stimulus0.0358454929048809
GO:0050790regulation of catalytic activity0.0367663802864149
GO:0019992diacylglycerol binding0.0369374221561485
GO:0030425dendrite0.039250326057089
GO:0051583dopamine uptake0.039250326057089
GO:0007217tachykinin signaling pathway0.039250326057089
GO:0001591dopamine D2 receptor-like receptor activity0.039250326057089
GO:0060160negative regulation of dopamine receptor signaling pathway0.039250326057089
GO:0048149behavioral response to ethanol0.039250326057089
GO:0051934catecholamine uptake during transmission of nerve impulse0.039250326057089
GO:0043278response to morphine0.039250326057089
GO:0060124positive regulation of growth hormone secretion0.039250326057089
GO:0014072response to isoquinoline alkaloid0.039250326057089
GO:0060159regulation of dopamine receptor signaling pathway0.039250326057089
GO:0051937catecholamine transport0.039250326057089
GO:0005083small GTPase regulator activity0.0431594941669944
GO:0030334regulation of cell migration0.0446173629943963
GO:0002028regulation of sodium ion transport0.0491852084840403
GO:0060123regulation of growth hormone secretion0.0491852084840403
GO:0032228regulation of synaptic transmission, GABAergic0.0491852084840403
GO:0051898negative regulation of protein kinase B signaling cascade0.0491852084840403
GO:0003091renal water homeostasis0.0491852084840403
GO:0004865type 1 serine/threonine specific protein phosphatase inhibitor activity0.0491852084840403
GO:0051932synaptic transmission, GABAergic0.0491852084840403
GO:0030146diuresis0.0491852084840403



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)7.71e-1023
neuroblast (sensu Vertebrata)7.71e-1023

Uber Anatomy
Ontology termp-valuen
gray matter1.35e-3134
regional part of nervous system6.72e-3154
neural tube4.28e-3052
neural rod4.28e-3052
future spinal cord4.28e-3052
neural keel4.28e-3052
brain grey matter6.50e-2729
regional part of telencephalon6.50e-2729
telencephalon6.50e-2729
brain1.60e-2547
future brain1.60e-2547
anterior neural tube2.64e-2440
regional part of brain4.27e-2446
central nervous system8.18e-2473
nervous system6.23e-2375
regional part of forebrain6.72e-2339
forebrain6.72e-2339
future forebrain6.72e-2339
neurectoderm7.97e-2364
neural plate7.97e-2364
presumptive neural plate7.97e-2364
regional part of cerebral cortex1.92e-1917
occipital lobe5.10e-1910
visual cortex5.10e-1910
neocortex5.10e-1910
ecto-epithelium5.96e-1973
pre-chordal neural plate1.49e-1849
cerebral cortex1.23e-1721
cerebral hemisphere1.23e-1721
pallium1.23e-1721
ectoderm-derived structure3.62e-1695
ectoderm3.62e-1695
presumptive ectoderm3.62e-1695
structure with developmental contribution from neural crest2.73e-1392
basal ganglion1.78e-108
nuclear complex of neuraxis1.78e-108
aggregate regional part of brain1.78e-108
collection of basal ganglia1.78e-108
cerebral subcortex1.78e-108
tube3.82e-09114
anatomical conduit5.05e-08122
regional part of midbrain1.35e-074
midbrain1.35e-074
presumptive midbrain1.35e-074
midbrain neural tube1.35e-074
spinal cord3.66e-076
dorsal region element3.66e-076
dorsum3.66e-076


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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