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Coexpression cluster:C3079

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Full id: C3079_caudate_parietal_amygdala_hippocampus_brain_occipital_medulla



Phase1 CAGE Peaks

Hg19::chr11:10715215..10715235,-p5@MRVI1
Hg19::chr11:10715449..10715466,-p12@MRVI1
Hg19::chr11:10715502..10715516,-p9@MRVI1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.14e-59115
neural tube2.13e-3657
neural rod2.13e-3657
future spinal cord2.13e-3657
neural keel2.13e-3657
regional part of brain6.78e-3659
brain2.09e-3269
future brain2.09e-3269
central nervous system1.48e-3082
anterior neural tube2.74e-2842
regional part of forebrain1.55e-2741
forebrain1.55e-2741
future forebrain1.55e-2741
regional part of nervous system1.07e-2694
nervous system1.07e-2694
neural plate1.82e-2686
presumptive neural plate1.82e-2686
neurectoderm4.89e-2590
telencephalon5.05e-2534
gray matter5.27e-2534
brain grey matter5.27e-2534
regional part of telencephalon3.94e-2433
cerebral hemisphere3.63e-2332
pre-chordal neural plate1.84e-1861
anterior region of body4.43e-18129
craniocervical region4.43e-18129
head1.40e-17123
regional part of cerebral cortex2.55e-1722
cerebral cortex1.29e-1625
pallium1.29e-1625
neocortex1.92e-1520
ectoderm-derived structure3.26e-15169
ectoderm1.03e-14173
presumptive ectoderm1.03e-14173
organism subdivision1.56e-13365
organ1.93e-11511
nucleus of brain4.00e-109
neural nucleus4.00e-109
basal ganglion4.81e-109
nuclear complex of neuraxis4.81e-109
aggregate regional part of brain4.81e-109
collection of basal ganglia4.81e-109
cerebral subcortex4.81e-109
posterior neural tube3.67e-0915
chordal neural plate3.67e-0915
brainstem1.61e-088
telencephalic nucleus2.39e-087
organ part3.20e-08219
anatomical cluster3.38e-08286
anatomical conduit3.85e-08241
tube7.63e-08194
cell layer1.13e-07312
segmental subdivision of nervous system1.64e-0713
epithelium4.25e-07309
gyrus5.16e-076
segmental subdivision of hindbrain5.79e-0712
hindbrain5.79e-0712
presumptive hindbrain5.79e-0712
multi-cellular organism6.96e-07659


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.