CL:0000115: Difference between revisions
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|located_in= | |located_in= | ||
|name=endothelial cell | |name=endothelial cell | ||
|namespace= | |namespace=FANTOM | ||
|obo_creation_date= | |obo_creation_date= | ||
|part_of= | |part_of= | ||
Latest revision as of 16:30, 12 September 2014
| Name: | endothelial cell | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://63.198.234.228/OpenFMA/Endothelial%20cell.html, https://sourceforge.net/tracker/?func | ||
| Xrefs: |
| ||
| Synonyms: | "endotheliocyte" EXACT [] | ||
| Comments: | From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | CL:0000213(lining cell),CL:0002078(meso-epithelial cell) |
|---|
Children
| is a: | CL:0002139 (endothelial cell of vascular tree),CL:0002188 (glomerular endothelial cell),CL:0002262 (endothelial cell of sinusoid),CL:0002367 (trabecular meshwork cell),FF:13595-146E4 (liver sinusoidal endothelial cells, sham operation, biol_rep1),FF:13596-146E5 (liver sinusoidal endothelial cells, sham operation, biol_rep2),FF:13597-146E6 (liver sinusoidal endothelial cells, sham operation, biol_rep3),FF:13598-146E7 (liver sinusoidal endothelial cells, partial hepatectomy, 02hr, biol_rep1),FF:13599-146E8 (liver sinusoidal endothelial cells, partial hepatectomy, 02hr, biol_rep2),FF:13600-146E9 (liver sinusoidal endothelial cells, partial hepatectomy, 02hr, biol_rep3),FF:13601-146F1 (liver sinusoidal endothelial cells, partial hepatectomy, 30hr, biol_rep1),FF:13602-146F2 (liver sinusoidal endothelial cells, partial hepatectomy, 30hr, biol_rep2),FF:13603-146F3 (liver sinusoidal endothelial cells, partial hepatectomy, 30hr, biol_rep3),FF:13604-146F4 (liver sinusoidal endothelial cells, partial hepatectomy, 48hr, biol_rep1),FF:13605-146F5 (liver sinusoidal endothelial cells, partial hepatectomy, 48hr, biol_rep2),FF:13606-146F6 (liver sinusoidal endothelial cells, partial hepatectomy, 48hr, biol_rep3),FF:13607-146F7 (liver sinusoidal endothelial cells, partial hepatectomy, week01, biol_rep1),FF:13608-146F8 (liver sinusoidal endothelial cells, partial hepatectomy, week01, biol_rep2),FF:13609-146F9 (liver sinusoidal endothelial cells, partial hepatectomy, week01, biol_rep3) |
|---|---|
| derives from: | FF:0000046 (human endothelial cell sample) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 11207-116A1 (Endothelial Cells - Aortic, donor0)
- 11229-116C5 (CD14+ monocyte derived endothelial progenitor cells, donor1)
- 11236-116D3 (Endothelial Cells - Lymphatic, donor1)
- 11243-116E1 (Endothelial Cells - Umbilical vein, donor1)
- 11263-116G3 (Endothelial Cells - Aortic, donor1)
- 11264-116G4 (Endothelial Cells - Artery, donor1)
- 11265-116G5 (Endothelial Cells - Microvascular, donor1)
- 11266-116G6 (Endothelial Cells - Thoracic, donor1)
- 11267-116G7 (Endothelial Cells - Vein, donor1)
- 11310-117C5 (CD14+ monocyte derived endothelial progenitor cells, donor2)
... further results Mouse (Mus musculus)
- 11207-116A1 (Endothelial Cells - Aortic, donor0)
- 11229-116C5 (CD14+ monocyte derived endothelial progenitor cells, donor1)
- 11236-116D3 (Endothelial Cells - Lymphatic, donor1)
- 11243-116E1 (Endothelial Cells - Umbilical vein, donor1)
- 11263-116G3 (Endothelial Cells - Aortic, donor1)
- 11264-116G4 (Endothelial Cells - Artery, donor1)
- 11265-116G5 (Endothelial Cells - Microvascular, donor1)
- 11266-116G6 (Endothelial Cells - Thoracic, donor1)
- 11267-116G7 (Endothelial Cells - Vein, donor1)
- 11310-117C5 (CD14+ monocyte derived endothelial progenitor cells, donor2)
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000115 (endothelial cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 9.88e-148 | FFCP PHASE2:Hg19::chr6:3753188..3753192,-#_06bc30e74497af619d61975e77d8eb98 | p@chr6:3753188..3753192, - |
| 9.88e-148 | FFCP PHASE1:Hg19::chr6:3753188..3753192,-#_06bc30e74497af619d61975e77d8eb98 | p@chr6:3753188..3753192, - |
| 1.61e-140 | FFCP PHASE2:Hg19::chr2:56216687..56216727,-#_fab41e54c2e336d47c48c7d6dee52670 | p1@MIR216A |
| 1.61e-140 | FFCP PHASE1:Hg19::chr2:56216687..56216727,-#_fab41e54c2e336d47c48c7d6dee52670 | p1@MIR216A |
| 6.06e-136 | FFCP PHASE1:Hg19::chr17:62084108..62084111,-#_9a0069514c9294f599f7e5cc7fbf874b | p5@ICAM2 |
| 6.06e-136 | FFCP PHASE2:Hg19::chr17:62084108..62084111,-#_9a0069514c9294f599f7e5cc7fbf874b | p5@ICAM2 |
| 9.36e-136 | FFCP PHASE2:Hg19::chr11:124761247..124761258,-#_85f7ac7e0263a7f05e6cc84e9456b9d2 | p@chr11:124761247..124761258, - |
| 9.36e-136 | FFCP PHASE1:Hg19::chr11:124761247..124761258,-#_85f7ac7e0263a7f05e6cc84e9456b9d2 | p@chr11:124761247..124761258, - |
| 8.29e-123 | FFCP PHASE1:Hg19::chr16:2220383..2220402,+#_0a24232b2879c978fc4e9db6fa2d5b69 | p@chr16:2220383..2220402, + |
| 8.29e-123 | FFCP PHASE2:Hg19::chr16:2220383..2220402,+#_0a24232b2879c978fc4e9db6fa2d5b69 | p@chr16:2220383..2220402, + |
| 7.69e-118 | FFCP PHASE1:Hg19::chrX:71299684..71299699,+#_9b523ba8e131c3ff26b28cd1106422cc | p@chrX:71299684..71299699, + |
| 7.69e-118 | FFCP PHASE2:Hg19::chrX:71299684..71299699,+#_9b523ba8e131c3ff26b28cd1106422cc | p@chrX:71299684..71299699, + |
| 8.89e-118 | FFCP PHASE1:Hg19::chr5:95920642..95920681,+#_21ce1d641a2177218ecff1a2973dc1c5 | p1@ENST00000513158 |
| 8.89e-118 | FFCP PHASE2:Hg19::chr5:95920642..95920681,+#_21ce1d641a2177218ecff1a2973dc1c5 | p1@ENST00000513158 |
| 2.23e-117 | FFCP PHASE1:Hg19::chr13:32835894..32835907,+#_785c732e886f06e401cd15af7c92f860 | p@chr13:32835894..32835907, + |
| 2.23e-117 | FFCP PHASE2:Hg19::chr13:32835894..32835907,+#_785c732e886f06e401cd15af7c92f860 | p@chr13:32835894..32835907, + |
| 3.21e-114 | FFCP PHASE1:Hg19::chr18:33047117..33047138,-#_381dcad6998a74e5410f9a824c731022 | p@chr18:33047117..33047138, - |
| 3.21e-114 | FFCP PHASE2:Hg19::chr18:33047117..33047138,-#_381dcad6998a74e5410f9a824c731022 | p@chr18:33047117..33047138, - |
| 5.66e-114 | FFCP PHASE1:Hg19::chr15:39423060..39423066,+#_9bcfe4f795a9e4c53d755f86ed810026 | p@chr15:39423060..39423066, + |
| 5.66e-114 | FFCP PHASE2:Hg19::chr15:39423060..39423066,+#_9bcfe4f795a9e4c53d755f86ed810026 | p@chr15:39423060..39423066, + |
| 5.52e-113 | FFCP PHASE1:Hg19::chr18:33046982..33046991,-#_684b3e4bb6885f0a1d1b627d7f2e3c99 | p@chr18:33046982..33046991, - |
| 5.52e-113 | FFCP PHASE2:Hg19::chr18:33046982..33046991,-#_684b3e4bb6885f0a1d1b627d7f2e3c99 | p@chr18:33046982..33046991, - |
| 4.6e-112 | FFCP PHASE2:Hg19::chrX:15518894..15518905,+#_16f64d24281979e3f09e9ffb7a1ff9b0 | p2@BMX |
| 4.6e-112 | FFCP PHASE1:Hg19::chrX:15518894..15518905,+#_16f64d24281979e3f09e9ffb7a1ff9b0 | p2@BMX |
| 2.66e-111 | FFCP PHASE1:Hg19::chr12:105863654..105863682,+#_25731f1147645a59858d91acc0ec7a96 | p@chr12:105863654..105863682, + |
| 2.66e-111 | FFCP PHASE2:Hg19::chr12:105863654..105863682,+#_25731f1147645a59858d91acc0ec7a96 | p@chr12:105863654..105863682, + |
| 1.63e-110 | FFCP PHASE2:Hg19::chr14:38725249..38725254,-#_e37384ebfd73de880ebb5562b9abcbcd | p6@CLEC14A |
| 1.63e-110 | FFCP PHASE1:Hg19::chr14:38725249..38725254,-#_e37384ebfd73de880ebb5562b9abcbcd | p6@CLEC14A |
| 7.97e-110 | FFCP PHASE2:Hg19::chr14:38725228..38725236,-#_a8b40fb330c1d3e81fba7f2f8ed0876b | p5@CLEC14A |
| 7.97e-110 | FFCP PHASE1:Hg19::chr14:38725228..38725236,-#_a8b40fb330c1d3e81fba7f2f8ed0876b | p5@CLEC14A |
| 6.56e-109 | FFCP PHASE1:Hg19::chr18:33047157..33047168,-#_6b2dc6ff68fb7578d5809bc92e1707c1 | p@chr18:33047157..33047168, - |
| 6.56e-109 | FFCP PHASE2:Hg19::chr18:33047157..33047168,-#_6b2dc6ff68fb7578d5809bc92e1707c1 | p@chr18:33047157..33047168, - |
| 7.47e-109 | FFCP PHASE1:Hg19::chr12:105863636..105863650,+#_8ad218010ff3980fae406f8e73352966 | p@chr12:105863636..105863650, + |
| 7.47e-109 | FFCP PHASE2:Hg19::chr12:105863636..105863650,+#_8ad218010ff3980fae406f8e73352966 | p@chr12:105863636..105863650, + |
| 1.87e-108 | FFCP PHASE2:Hg19::chr3:43538305..43538325,-#_66692a06d918de47eff75e48ef7cf4d1 | p@chr3:43538305..43538325, - |
| 1.87e-108 | FFCP PHASE1:Hg19::chr3:43538305..43538325,-#_66692a06d918de47eff75e48ef7cf4d1 | p@chr3:43538305..43538325, - |
| 1.97e-108 | FFCP PHASE1:Hg19::chr10:129785574..129785580,+#_f65ae4b4706cd3cd3f7135eedd961d5b | p14@PTPRE |
| 1.97e-108 | FFCP PHASE2:Hg19::chr10:129785574..129785580,+#_f65ae4b4706cd3cd3f7135eedd961d5b | p14@PTPRE |
| 2.37e-108 | FFCP PHASE2:Hg19::chr9:139543390..139543404,+#_246a11e56064fdca30885871771165af | p@chr9:139543390..139543404, + |
| 2.37e-108 | FFCP PHASE1:Hg19::chr9:139543390..139543404,+#_246a11e56064fdca30885871771165af | p@chr9:139543390..139543404, + |
| 9.99e-107 | FFCP PHASE1:Hg19::chr19:4639579..4639589,+#_07c5ca06b169e93ec9904b869098b483 | p2@TNFAIP8L1 |
| 9.99e-107 | FFCP PHASE2:Hg19::chr19:4639579..4639589,+#_07c5ca06b169e93ec9904b869098b483 | p2@TNFAIP8L1 |
| 5.19e-104 | FFCP PHASE1:Hg19::chr13:32835912..32835936,+#_a7d084e376072fc3d27dae6989cd2181 | p@chr13:32835912..32835936, + |
| 5.19e-104 | FFCP PHASE2:Hg19::chr13:32835912..32835936,+#_a7d084e376072fc3d27dae6989cd2181 | p@chr13:32835912..32835936, + |
| 8.89e-103 | FFCP PHASE1:Hg19::chr13:32838801..32838818,+#_e6d1da271bb41cc6b46da58bd6f8048a | p9@FRY |
| 8.89e-103 | FFCP PHASE2:Hg19::chr13:32838801..32838818,+#_e6d1da271bb41cc6b46da58bd6f8048a | p9@FRY |
| 3.87e-101 | FFCP PHASE1:Hg19::chr17:47287786..47287797,+#_beaba73ecc618e5758f5218112744586 | p4@ABI3 |
| 3.87e-101 | FFCP PHASE2:Hg19::chr17:47287786..47287797,+#_beaba73ecc618e5758f5218112744586 | p4@ABI3 |
| 1.92e-100 | FFCP PHASE1:Hg19::chr19:41985048..41985050,-#_c61c32af69712cdc8ae290920468e219 | p@chr19:41985048..41985050, - |
| 1.92e-100 | FFCP PHASE2:Hg19::chr19:41985048..41985050,-#_c61c32af69712cdc8ae290920468e219 | p@chr19:41985048..41985050, - |
| 9.53e-100 | FFCP PHASE1:Hg19::chr16:66413317..66413328,+#_de3d3861818eb9acef73a3d5a70e3250 | p1@AB385138 |
| 9.53e-100 | FFCP PHASE2:Hg19::chr16:66413317..66413328,+#_de3d3861818eb9acef73a3d5a70e3250 | p1@AB385138 |
| 9.54e-99 | FFCP PHASE1:Hg19::chr12:118112251..118112272,-#_6aa08e6bfd1d85a8e73a8f040411daeb | p12@KSR2 |
| 9.54e-99 | FFCP PHASE2:Hg19::chr12:118112251..118112272,-#_6aa08e6bfd1d85a8e73a8f040411daeb | p12@KSR2 |
| 2.11e-98 | FFCP PHASE2:Hg19::chr7:150329732..150329739,-#_5f3978443f6c36d83318fdb322df882f | p8@GIMAP6 |
| 2.11e-98 | FFCP PHASE1:Hg19::chr7:150329732..150329739,-#_5f3978443f6c36d83318fdb322df882f | p8@GIMAP6 |
| 1.26e-97 | FFCP PHASE1:Hg19::chr5:176433333..176433349,-#_ec81fa9cd193f97b0802ecbb0f1e2d93 | p11@UIMC1 |
| 1.26e-97 | FFCP PHASE2:Hg19::chr5:176433333..176433349,-#_ec81fa9cd193f97b0802ecbb0f1e2d93 | p11@UIMC1 |
| 4.26e-97 | FFCP PHASE2:Hg19::chr10:50153735..50153750,+#_f9bc43df97004d7f744aa7deee63561c | p6@WDFY4 |
| 4.26e-97 | FFCP PHASE1:Hg19::chr10:50153735..50153750,+#_f9bc43df97004d7f744aa7deee63561c | p6@WDFY4 |
| 5.01e-97 | FFCP PHASE1:Hg19::chr12:105863705..105863718,+#_6539287d81ebfcfefb27a97039d4d2d8 | p@chr12:105863705..105863718, + |
| 5.01e-97 | FFCP PHASE2:Hg19::chr12:105863705..105863718,+#_6539287d81ebfcfefb27a97039d4d2d8 | p@chr12:105863705..105863718, + |
| 3.98e-96 | FFCP PHASE2:Hg19::chr10:99655692..99655725,-#_51ba59a5683c8361aa6aa645b5701691 | p@chr10:99655692..99655725, - |
| 3.98e-96 | FFCP PHASE1:Hg19::chr10:99655692..99655725,-#_51ba59a5683c8361aa6aa645b5701691 | p@chr10:99655692..99655725, - |
| 8.76e-96 | FFCP PHASE1:Hg19::chr11:124767798..124767809,-#_68fa61fd333ba639cb688dc6931ca6c1 | p3@ROBO4 |
| 8.76e-96 | FFCP PHASE2:Hg19::chr11:124767798..124767809,-#_68fa61fd333ba639cb688dc6931ca6c1 | p3@ROBO4 |
| 1.94e-95 | FFCP PHASE1:Hg19::chr12:80084018..80084035,-#_64578b003dc87499ed0c1e19f3483119 | p17@PAWR |
| 1.94e-95 | FFCP PHASE2:Hg19::chr12:80084018..80084035,-#_64578b003dc87499ed0c1e19f3483119 | p17@PAWR |
| 6.54e-95 | FFCP PHASE1:Hg19::chr17:75137460..75137485,+#_f0fa33f8112dd683b0eccd4b617b414a | p@chr17:75137460..75137485, + |
| 6.54e-95 | FFCP PHASE2:Hg19::chr17:75137460..75137485,+#_f0fa33f8112dd683b0eccd4b617b414a | p@chr17:75137460..75137485, + |
| 1.27e-94 | FFCP PHASE1:Hg19::chr6:132455180..132455197,+#_ccf5128a2e6e14689f6343d2310460fc | p2@LOC100507254 |
| 1.27e-94 | FFCP PHASE2:Hg19::chr6:132455180..132455197,+#_ccf5128a2e6e14689f6343d2310460fc | p2@LOC100507254 |
| 1.3e-93 | FFCP PHASE1:Hg19::chr3:58034268..58034295,+#_65485d3061024adcf41fafa0db23adcd | p@chr3:58034268..58034295, + |
| 1.3e-93 | FFCP PHASE2:Hg19::chr3:58034268..58034295,+#_65485d3061024adcf41fafa0db23adcd | p@chr3:58034268..58034295, + |
| 1.98e-93 | FFCP PHASE2:Hg19::chr6:78171774..78171792,+#_90ab8e2a9b473a97de881613c2652f66 | p@chr6:78171774..78171792, + |
| 1.98e-93 | FFCP PHASE1:Hg19::chr6:78171774..78171792,+#_90ab8e2a9b473a97de881613c2652f66 | p@chr6:78171774..78171792, + |
| 1.01e-92 | FFCP PHASE2:Hg19::chr19:47220191..47220198,-#_56a3ccd9f872e025444523751eec91fe | p14@PRKD2 |
| 1.01e-92 | FFCP PHASE1:Hg19::chr19:47220191..47220198,-#_56a3ccd9f872e025444523751eec91fe | p14@PRKD2 |
| 1.93e-92 | FFCP PHASE1:Hg19::chr18:33047039..33047063,-#_b583652e47286b1cac8d3462d285a2fd | p@chr18:33047039..33047063, - |
| 1.93e-92 | FFCP PHASE2:Hg19::chr18:33047039..33047063,-#_b583652e47286b1cac8d3462d285a2fd | p@chr18:33047039..33047063, - |
| 2.0e-92 | FFCP PHASE2:Hg19::chr7:139741594..139741615,-#_0a111c3378aa97f5ed3ee9bf782840ae | p5@PARP12 |
| 2.0e-92 | FFCP PHASE2:Hg19::chr18:33047076..33047099,-#_0a111c3378aa97f5ed3ee9bf782840ae | p@chr18:33047076..33047099, - |
| 2.0e-92 | FFCP PHASE1:Hg19::chr13:32838839..32838850,+#_0a111c3378aa97f5ed3ee9bf782840ae | p20@FRY |
| 2.0e-92 | FFCP PHASE2:Hg19::chr13:32838839..32838850,+#_0a111c3378aa97f5ed3ee9bf782840ae | p20@FRY |
| 2.0e-92 | FFCP PHASE1:Hg19::chr7:139741594..139741615,-#_0a111c3378aa97f5ed3ee9bf782840ae | p5@PARP12 |
| 2.0e-92 | FFCP PHASE1:Hg19::chr18:33047076..33047099,-#_0a111c3378aa97f5ed3ee9bf782840ae | p@chr18:33047076..33047099, - |
| 6.65e-92 | FFCP PHASE1:Hg19::chr12:71031247..71031262,-#_4a40390335d2c543eefdf3784f1ff3db | p7@PTPRB |
| 6.65e-92 | FFCP PHASE2:Hg19::chr12:71031247..71031262,-#_4a40390335d2c543eefdf3784f1ff3db | p7@PTPRB |
| 1.75e-91 | FFCP PHASE1:Hg19::chr10:50153703..50153720,+#_6ca380c4836d4b130c90080dff551db7 | p7@WDFY4 |
| 1.75e-91 | FFCP PHASE2:Hg19::chr10:50153703..50153720,+#_6ca380c4836d4b130c90080dff551db7 | p7@WDFY4 |
| 2.48e-91 | FFCP PHASE2:Hg19::chr21:39869867..39869880,-#_b80cc45b9e6a64bf29bf6488c43165c0 | p@chr21:39869867..39869880, - |
| 2.48e-91 | FFCP PHASE1:Hg19::chr21:39869867..39869880,-#_b80cc45b9e6a64bf29bf6488c43165c0 | p@chr21:39869867..39869880, - |
| 5.09e-91 | FFCP PHASE2:Hg19::chr11:62344721..62344758,-#_8ca4b5923b1ca1721d461f978b2879d5 | p2@TUT1 |
| 5.09e-91 | FFCP PHASE1:Hg19::chr11:62344721..62344758,-#_8ca4b5923b1ca1721d461f978b2879d5 | p2@TUT1 |
| 1.11e-90 | FFCP PHASE1:Hg19::chr1:208063620..208063634,-#_931992a8819a1541b7815c9a4e82fbba | p4@CD34 |
| 1.11e-90 | FFCP PHASE2:Hg19::chr1:208063620..208063634,-#_931992a8819a1541b7815c9a4e82fbba | p4@CD34 |
| 1.26e-90 | FFCP PHASE1:Hg19::chr2:225266779..225266786,-#_97f6c73a7784fea0da7857c3c9bdd610 | p4@FAM124B |
| 1.26e-90 | FFCP PHASE2:Hg19::chr2:225266779..225266786,-#_97f6c73a7784fea0da7857c3c9bdd610 | p4@FAM124B |
| 2.6e-89 | FFCP PHASE2:Hg19::chr7:39663061..39663072,+#_36f5fa3e393cc28b9d225cc42eace732 | p6@RALA |
| 2.6e-89 | FFCP PHASE1:Hg19::chr7:39663061..39663072,+#_36f5fa3e393cc28b9d225cc42eace732 | p6@RALA |
