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MCL coexpression mm9:3183: Difference between revisions

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{{MCL_coexpression_mm9
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protein kinase activity;0.0174179756208422;19091!GO:0004690;cyclic nucleotide-dependent protein kinase activity;0.0174179756208422;19091!GO:0019002;GMP binding;0.0174179756208422;19091!GO:0030553;cGMP binding;0.0174179756208422;19091!GO:0005861;troponin complex;0.0174179756208422;21955!GO:0005952;cAMP-dependent protein kinase complex;0.0174179756208422;19091!GO:0008603;cAMP-dependent protein kinase regulator activity;0.019904621542287;19091!GO:0005865;striated muscle thin filament;0.0232195130947285;21955!GO:0030551;cyclic nucleotide binding;0.0245074709588446;19091!GO:0006937;regulation of muscle contraction;0.0382943471902504;21955!GO:0016358;dendrite development;0.0411359186902933;19091!GO:0001764;neuron migration;0.0458019258202438;19091!GO:0019887;protein kinase regulator activity;0.0458019258202438;19091!GO:0030017;sarcomere;0.0458019258202438;21955!GO:0043234;protein complex;0.0458019258202438;19091,21955!GO:0044449;contractile fiber part;0.0458019258202438;21955!GO:0019207;kinase regulator activity;0.0458019258202438;19091!GO:0030016;myofibril;0.0458019258202438;21955!GO:0043292;contractile fiber;0.0458019258202438;21955!GO:0003012;muscle system process;0.0458019258202438;21955!GO:0006936;muscle contraction;0.0458019258202438;21955!GO:0005200;structural constituent of 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|gostat_on_MCL_coexpression=GO:0004692;cGMP-dependent protein kinase activity;0.0174179756208422;19091!GO:0004690;cyclic nucleotide-dependent protein kinase activity;0.0174179756208422;19091!GO:0019002;GMP binding;0.0174179756208422;19091!GO:0030553;cGMP binding;0.0174179756208422;19091!GO:0005861;troponin complex;0.0174179756208422;21955!GO:0005952;cAMP-dependent protein kinase complex;0.0174179756208422;19091!GO:0008603;cAMP-dependent protein kinase regulator activity;0.019904621542287;19091!GO:0005865;striated muscle thin filament;0.0232195130947285;21955!GO:0030551;cyclic nucleotide binding;0.0245074709588446;19091!GO:0006937;regulation of muscle contraction;0.0382943471902504;21955!GO:0016358;dendrite development;0.0411359186902933;19091!GO:0001764;neuron migration;0.0458019258202438;19091!GO:0019887;protein kinase regulator activity;0.0458019258202438;19091!GO:0030017;sarcomere;0.0458019258202438;21955!GO:0043234;protein complex;0.0458019258202438;19091,21955!GO:0044449;contractile fiber part;0.0458019258202438;21955!GO:0019207;kinase regulator activity;0.0458019258202438;19091!GO:0030016;myofibril;0.0458019258202438;21955!GO:0043292;contractile fiber;0.0458019258202438;21955!GO:0003012;muscle system process;0.0458019258202438;21955!GO:0006936;muscle contraction;0.0458019258202438;21955!GO:0005200;structural constituent of cytoskeleton;0.0463473928236306;21955!
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|ontology_enrichment_uberon=UBERON:0000026!4.64e-08!12;UBERON:0004708!4.64e-08!12;UBERON:0002101!4.64e-08!12;UBERON:0004357!4.64e-08!12;UBERON:0004347!4.64e-08!12;UBERON:0005732!4.64e-08!12;UBERON:0005733!4.64e-08!12;UBERON:0010707!4.07e-07!13
|tfbs_overrepresentation_for_novel_motifs=0.752782,0.193418,0.722405,0.801166,0.587814,0.81763,0.919454,0.467321,0.479531,0.235304,0.870507,0.906098,0.467629,0.933025,0.608226,0,1.14208,1.41496,1.138,0.328717,0.679146,0.756749,0.932027,0.585919,0.731217,0.963352,0.437236,0.841386,0.64294,0.380786,0.825437,1.24901,0.575271,0.411696,0.608816,0.144706,0.563758,0.902078,0.536514,0.50014,0.582863,0.831295,1.33334,0.610669,0.156582,0.788421,1.05665,0.859154,0.663409,0.646474,1.12346,0.99279,0.971403,1.3966,1.41464,0.940919,0.657156,0.891887,0.425455,0.938668,1.22795,1.00308,0.494668,1.11142,0.953187,1.15459,1.55483,1.90983,1.22303,1.7608,0.700291,0.474956,0.284975,1.44925,0.416814,0.402065,0.411601,1.04436,1.20986,0.684144,0.476502,1.16055,1.00151,0.459035,1.32978,0.181575,0.195254,0.380977,1.06194,2.07346,1.62608,1.33496,1.26245,0.595071,0.531443,0.509215,0.464141,1.26539,1.05692,0.352122,0.563856,1.24872,1.37854,1.12409,1.12297,0.830796,1.18646,0.854628,0.689894,0.681267,0.744607,1.38039,0.685481,0.876299,1.63327,0.580657,0.212464,0.805461,1.14346,0.559153,1.45481,1.08896,0.965352,1.04338,1.68841,1.21376,0.928483,1.25534,1.55328,0.598722,1.36093,0.792832,1.52297,2.19629,1.65529,0.273451,1.79943,0.832891,1.60513,2.44352,2.04137,1.55966,0.978551,1.26,1.11604,0.831808,1.06002,2.40374,0.765221,0.589976,0.38417,0.260379,1.39822,0.516739,0.954936,1.48249,0.993889,0.622823,0.749933,0.762177,1.61484,1.32889,1.21423,0.741984,1.11251,0.94678,0.562367,0.904334,0.135528
|tfbs_overrepresentation_jaspar=MA0003.1;0.0699972,MA0004.1;0.801718,MA0006.1;0.60285,MA0007.1;0.784593,MA0009.1;1.27673,MA0014.1;0.133574,MA0017.1;0.635031,MA0019.1;1.08369,MA0024.1;1.23079,MA0025.1;1.51835,MA0027.1;2.9431,MA0028.1;0.61552,MA0029.1;1.20789,MA0030.1;1.21482,MA0031.1;1.17722,MA0038.1;0.963265,MA0040.1;1.28983,MA0041.1;0.714279,MA0042.1;1.66761,MA0043.1;1.3775,MA0046.1;1.31428,MA0048.1;0.353763,MA0050.1;0.845669,MA0051.1;0.973068,MA0052.1;1.29825,MA0055.1;0.190475,MA0056.1;0,MA0057.1;0.337566,MA0058.1;0.690848,MA0059.1;0.705317,MA0060.1;0.502699,MA0061.1;0.5406,MA0063.1;0,MA0066.1;0.951196,MA0067.1;1.63197,MA0068.1;0.343188,MA0069.1;1.29861,MA0070.1;1.28847,MA0071.1;0.844726,MA0072.1;1.2796,MA0073.1;0.00834468,MA0074.1;0.911576,MA0076.1;0.657929,MA0077.1;1.2569,MA0078.1;1.0091,MA0081.1;0.732313,MA0083.1;1.37668,MA0084.1;1.96428,MA0087.1;1.33189,MA0088.1;0.27999,MA0089.1;0,MA0090.1;0.762482,MA0091.1;0.816659,MA0092.1;0.762845,MA0093.1;0.62555,MA0095.1;0,MA0098.1;0,MA0100.1;0.89873,MA0101.1;0.71579,MA0103.1;1.56167,MA0105.1;0.405648,MA0106.1;1.01755,MA0107.1;0.640607,MA0108.2;1.10817,MA0109.1;0,MA0111.1;0.778753,MA0113.1;0.986839,MA0114.1;1.3296,MA0115.1;1.38041,MA0116.1;0.602598,MA0117.1;1.34691,MA0119.1;0.716476,MA0122.1;1.36752,MA0124.1;1.57762,MA0125.1;1.5017,MA0130.1;0,MA0131.1;1.07881,MA0132.1;0,MA0133.1;0,MA0135.1;1.4152,MA0136.1;0.933582,MA0139.1;0.462282,MA0140.1;0.898603,MA0141.1;1.61065,MA0142.1;1.16183,MA0143.1;1.00467,MA0144.1;0.541532,MA0145.1;0.794492,MA0146.1;0.151124,MA0147.1;0.556853,MA0148.1;0.820161,MA0149.1;0.722227,MA0062.2;0.412742,MA0035.2;0.903829,MA0039.2;0.0481552,MA0138.2;1.07027,MA0002.2;0.466067,MA0137.2;0.668025,MA0104.2;0.48458,MA0047.2;0.962424,MA0112.2;0.29236,MA0065.2;0.79573,MA0150.1;0.784464,MA0151.1;0,MA0152.1;0.962542,MA0153.1;1.43238,MA0154.1;0.35067,MA0155.1;0.312898,MA0156.1;0.656895,MA0157.1;1.12772,MA0158.1;0,MA0159.1;0.569393,MA0160.1;0.823568,MA0161.1;0,MA0162.1;0.166722,MA0163.1;0.477233,MA0164.1;0.933981,MA0080.2;0.64167,MA0018.2;0.944669,MA0099.2;1.06348,MA0079.2;0.288542,MA0102.2;2.01714,MA0258.1;0.520639,MA0259.1;0.543506,MA0442.1;0
}}

Latest revision as of 19:42, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr19:30700005..30700027,-p@chr19:30700005..30700027
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Mm9::chr7:4464440..4464444,-p@chr7:4464440..4464444
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Mm9::chr7:4467569..4467584,-p1@Tnnt1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0004692cGMP-dependent protein kinase activity0.0174179756208422
GO:0004690cyclic nucleotide-dependent protein kinase activity0.0174179756208422
GO:0019002GMP binding0.0174179756208422
GO:0030553cGMP binding0.0174179756208422
GO:0005861troponin complex0.0174179756208422
GO:0005952cAMP-dependent protein kinase complex0.0174179756208422
GO:0008603cAMP-dependent protein kinase regulator activity0.019904621542287
GO:0005865striated muscle thin filament0.0232195130947285
GO:0030551cyclic nucleotide binding0.0245074709588446
GO:0006937regulation of muscle contraction0.0382943471902504
GO:0016358dendrite development0.0411359186902933
GO:0001764neuron migration0.0458019258202438
GO:0019887protein kinase regulator activity0.0458019258202438
GO:0030017sarcomere0.0458019258202438
GO:0043234protein complex0.0458019258202438
GO:0044449contractile fiber part0.0458019258202438
GO:0019207kinase regulator activity0.0458019258202438
GO:0030016myofibril0.0458019258202438
GO:0043292contractile fiber0.0458019258202438
GO:0003012muscle system process0.0458019258202438
GO:0006936muscle contraction0.0458019258202438
GO:0005200structural constituent of cytoskeleton0.0463473928236306



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
appendage4.64e-0812
paired limb/fin4.64e-0812
limb4.64e-0812
paired limb/fin bud4.64e-0812
limb bud4.64e-0812
limb/fin field4.64e-0812
limb field4.64e-0812
appendage girdle complex4.07e-0713


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0699972
MA0004.10.801718
MA0006.10.60285
MA0007.10.784593
MA0009.11.27673
MA0014.10.133574
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.11.51835
MA0027.12.9431
MA0028.10.61552
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.10.963265
MA0040.11.28983
MA0041.10.714279
MA0042.11.66761
MA0043.11.3775
MA0046.11.31428
MA0048.10.353763
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.10.190475
MA0056.10
MA0057.10.337566
MA0058.10.690848
MA0059.10.705317
MA0060.10.502699
MA0061.10.5406
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.10.343188
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.10.00834468
MA0074.10.911576
MA0076.10.657929
MA0077.11.2569
MA0078.11.0091
MA0081.10.732313
MA0083.11.37668
MA0084.11.96428
MA0087.11.33189
MA0088.10.27999
MA0089.10
MA0090.10.762482
MA0091.10.816659
MA0092.10.762845
MA0093.10.62555
MA0095.10
MA0098.10
MA0100.10.89873
MA0101.10.71579
MA0103.11.56167
MA0105.10.405648
MA0106.11.01755
MA0107.10.640607
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.11.3296
MA0115.11.38041
MA0116.10.602598
MA0117.11.34691
MA0119.10.716476
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.11.07881
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.10.933582
MA0139.10.462282
MA0140.10.898603
MA0141.11.61065
MA0142.11.16183
MA0143.11.00467
MA0144.10.541532
MA0145.10.794492
MA0146.10.151124
MA0147.10.556853
MA0148.10.820161
MA0149.10.722227
MA0062.20.412742
MA0035.20.903829
MA0039.20.0481552
MA0138.21.07027
MA0002.20.466067
MA0137.20.668025
MA0104.20.48458
MA0047.20.962424
MA0112.20.29236
MA0065.20.79573
MA0150.10.784464
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.35067
MA0155.10.312898
MA0156.10.656895
MA0157.11.12772
MA0158.10
MA0159.10.569393
MA0160.10.823568
MA0161.10
MA0162.10.166722
MA0163.10.477233
MA0164.10.933981
MA0080.20.64167
MA0018.20.944669
MA0099.21.06348
MA0079.20.288542
MA0102.22.01714
MA0258.10.520639
MA0259.10.543506
MA0442.10
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