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Coexpression cluster:C4771: Difference between revisions

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|ontology_enrichment_uberon=UBERON:0001049!2.37e-49!56;UBERON:0005068!2.37e-49!56;UBERON:0006241!2.37e-49!56;UBERON:0007135!2.37e-49!56;UBERON:0001017!8.32e-47!81;UBERON:0001016!1.29e-45!89;UBERON:0000073!1.07e-43!53;UBERON:0002616!1.07e-43!53;UBERON:0000955!1.49e-41!68;UBERON:0006238!1.49e-41!68;UBERON:0002780!2.15e-41!41;UBERON:0001890!2.15e-41!41;UBERON:0003080!2.15e-41!41;UBERON:0006240!2.15e-41!41;UBERON:0003075!2.76e-41!82;UBERON:0007284!2.76e-41!82;UBERON:0002346!7.54e-39!86;UBERON:0002619!5.03e-38!22;UBERON:0001950!1.25e-37!20;UBERON:0003528!2.19e-37!34;UBERON:0002020!2.19e-37!34;UBERON:0001893!4.19e-37!34;UBERON:0003056!1.19e-36!61;UBERON:0001869!1.29e-36!32;UBERON:0002791!2.94e-33!32;UBERON:0000956!5.54e-33!25;UBERON:0000203!5.54e-33!25;UBERON:0010371!4.95e-32!104;UBERON:0007023!1.01e-27!114;UBERON:0010314!6.00e-27!132;UBERON:0004121!4.04e-24!171;UBERON:0000924!4.04e-24!171;UBERON:0006601!4.04e-24!171;UBERON:0011216!9.50e-24!223;UBERON:0000200!7.41e-16!6;UBERON:0000477!1.81e-14!373;UBERON:0001871!1.92e-13!6;UBERON:0000064!1.18e-12!218;UBERON:0000025!1.50e-11!192;UBERON:0002298!1.61e-10!6;UBERON:0003076!2.03e-09!15;UBERON:0003057!2.03e-09!15;UBERON:0000481!3.95e-09!342;UBERON:0001870!4.12e-09!3;UBERON:0002021!4.85e-09!5;UBERON:0001872!8.58e-09!5;UBERON:0000483!1.22e-08!306;UBERON:0000349!1.87e-08!5;UBERON:0000119!1.93e-08!309;UBERON:0000988!3.09e-08!3;UBERON:0002240!6.19e-08!3;UBERON:0005174!6.19e-08!3;UBERON:0001137!6.19e-08!3;UBERON:0000062!1.07e-07!503;UBERON:0001778!1.38e-07!3;UBERON:0001775!1.38e-07!3;UBERON:0004111!2.69e-07!240
|ontology_enrichment_uberon=UBERON:0001049!2.37e-49!56;UBERON:0005068!2.37e-49!56;UBERON:0006241!2.37e-49!56;UBERON:0007135!2.37e-49!56;UBERON:0001017!8.32e-47!81;UBERON:0001016!1.29e-45!89;UBERON:0000073!1.07e-43!53;UBERON:0002616!1.07e-43!53;UBERON:0000955!1.49e-41!68;UBERON:0006238!1.49e-41!68;UBERON:0002780!2.15e-41!41;UBERON:0001890!2.15e-41!41;UBERON:0003080!2.15e-41!41;UBERON:0006240!2.15e-41!41;UBERON:0003075!2.76e-41!82;UBERON:0007284!2.76e-41!82;UBERON:0002346!7.54e-39!86;UBERON:0002619!5.03e-38!22;UBERON:0001950!1.25e-37!20;UBERON:0003528!2.19e-37!34;UBERON:0002020!2.19e-37!34;UBERON:0001893!4.19e-37!34;UBERON:0003056!1.19e-36!61;UBERON:0001869!1.29e-36!32;UBERON:0002791!2.94e-33!32;UBERON:0000956!5.54e-33!25;UBERON:0000203!5.54e-33!25;UBERON:0010371!4.95e-32!104;UBERON:0007023!1.01e-27!114;UBERON:0010314!6.00e-27!132;UBERON:0004121!4.04e-24!171;UBERON:0000924!4.04e-24!171;UBERON:0006601!4.04e-24!171;UBERON:0011216!9.50e-24!223;UBERON:0000200!7.41e-16!6;UBERON:0000477!1.81e-14!373;UBERON:0001871!1.92e-13!6;UBERON:0000064!1.18e-12!218;UBERON:0000025!1.50e-11!192;UBERON:0002298!1.61e-10!6;UBERON:0003076!2.03e-09!15;UBERON:0003057!2.03e-09!15;UBERON:0000481!3.95e-09!342;UBERON:0001870!4.12e-09!3;UBERON:0002021!4.85e-09!5;UBERON:0001872!8.58e-09!5;UBERON:0000483!1.22e-08!306;UBERON:0000349!1.87e-08!5;UBERON:0000119!1.93e-08!309;UBERON:0000988!3.09e-08!3;UBERON:0002240!6.19e-08!3;UBERON:0005174!6.19e-08!3;UBERON:0001137!6.19e-08!3;UBERON:0000062!1.07e-07!503;UBERON:0001778!1.38e-07!3;UBERON:0001775!1.38e-07!3;UBERON:0004111!2.69e-07!240
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443426,0.0377931,0.137332,0.0145999,0.0656973,0.211746,0.220538,0.0801488,0.0757897,0.161801,0.193215,0.0549034,0.0779715,0.0561838,0.0417636,0.0345419,0.0388736,0.254674,0.170307,0.201033,0.0488949,0.016278,0.370421,0.0330727,0.0694567,0.219556,0.0394698,0.0596469,0.103658,0.122476,0.108872,0.11002,0.0376172,0.0286025,0.00896808,0.144567,0.038848,0.0874516,0.0550279,0.144067,0.253693,0.217069,0.190048,0.131088,0.090504,0.237101,0.286988,0.0761239,0.172491,0.0818785,0.182701,0.335058,0.147698,0.141463,0.167267,0.140622,0.0889592,0.0538132,0.28711,0.0473033,0.094881,0.00315933,0.132886,0.0774373,0.109194,0.128564,0.131452,0.687347,0.448776,0.051838,0.0993999,0.0500365,0.061829,0.0755121,0.0936516,0.144075,0.0340203,0.0741807,0.277091,0.0122266,0.288159,0.21727,0.289306,0.119215,0.192475,0.177967,0.0465298,0.057571,0.047591,0.00174134,0.0608699,0.175319,0.300597,0.0713214,0.223874,0.291114,0.0355833,0.125606,0.175094,0.226002,0.000581378,0.206454,0.218192,0.108277,0.0673484,0.108748,0.0494066,0.0958493,0.205732,0.0755808,0.045654,0.110216,0.070276,0.226171,0.153469,0.0376916,0.13262,0.0450031,0.0539144,0.114242,0.0929549,0.172425,0.104948,0.221645,0.057168,0.234298,0.0759837,0.0457643,0.152372,0.194941,0.0257725,0.101607,0.060512,0.172982,0.340936,0.151597,0.0626744,0.191335,0.148574,0.034431,0.155821,0.0718905,0.0919008,0.0602373,0.144304,0.15063,0.0973823,0.15503,0.170295,0.193653,0.000479913,0.228144,0.251466,0.288096,0.11903,0.00362128,0.331451,0.113145,0.112651,0.186638,0.174776,0.0948451,0.264079,0.249049,0.140533,0.0997756,0.257598,0.103667,0.113069,0.025556,0.16791,0.09066,0.0597157,0.166967,0.188651,0.0813902,0.184948,0.156261,0.311847,0.161789,0.0590944,0.247324,0.178389,0.218229,0.231073,0.0972686,0.619906,0.0360851,0.0998546,0.131093,0.0434602,0.133616,0.103051,0.36927,0.449036,0.407369,0.231447,0.544776,0.43956,0.37006,0.42622,0.448797,0.197484,0.396996,0.36145,0.406019,0.381071,0.580441,0.643768,0.432035,0.366326,0.390366,0.145312,0.0334527,0.443185,0.522904,0.0199034,0.00127936,0.227104,0.518585,0.0734371,0.38649,0.284625,0.504757,0.192225,0.0437169,0.28907,0.164197,0.462688,0.287881,0.574635,0.478174,0.336276,0.132529,0.258219,0.446557,0.243383,0.191695,0.390974,0.149257,0.683217,0.161598,0.164332,0.0868402,0.496032,0.0795555,0.37357,0.200632,0.477353,0.069689,0.160298,0.185744,0.20342,0.200493,0.20558,0.300504,0.25656,0.425963,0.349197,0.383291,0.156104,0.141318,0.411941,0.0961477,0.314438,0.354789,0.163828,0.230581,0.120226,0.0448825,0.20075,0.314429,0.181415,0.282286,0.194707,0.24884,0.408413,0.516511,0.322213,0.656109,0.33942,0.000436901,0.387276,0.522605,0.000283063,0.537348,0.222037,0.416621,0.416292,0.462712,0.382478,0.579431,0.204817,0.452428,0.138871,0.673493,0.166905,0.19783,0.0833851,0.316453,0.48065,0.175199,0.332919,0.373557,0.523625,0.408861,0.365487,0.178743,0.00169836,0.363192,0.236011,0.203486,0.273398,0.375787,0.4466,0.351067,0.275347,0.269604,0.305885,0.241132,0.371414,0.30666,0.303709,0.0323359,0.386538,0.508064,0.250964,0.383276,0.457886,0.504711,0.220231,0.509064,0.196976,0.191517,0.463751,0.235208,0.307334,0.459728,0.283463,0.201728,0.472935,0.399569,0.273281,0.368095,0.275089,0.384593,0.47795,0.359231,0.339729,0.197805,0.608187,0.387069,0.332774,0.52832,0.0502872,0.266492,0.205413,0.17639,0.0779009,0.276869,0.205298,0.0337138,0.18966,0.258854,0.188263,0.0719199,0.264884,0.162568,0.19104,0.163057,0.219428,0.208013,0.0900729,0.0953646,0.166124,0.252184,0.378361,0.255516,0.20753,0.447185,0.179412,0.193601,0.220904,0.222977,0.341681,0.310674,0.21801,0.198614,0.186804,0.123324,0.199468,0.0325925,0.0933115,0.12405,0.179889,0.226869,0.27872,0.0855609,0.131118,0.20837,0.247588,0.222339,0.0673329,0.20847,0.266544,0.113092,0.145701,0.229428,0.162145,0.228955,0.168748,0.0384949,0.0660995,0.0521984,0.0455518,0.268741,0.201602,0.350452,0.154941,0.120196,0.0986735,0.108462,0.0595618,0.21593,0.158479,0.220319,0.195218,0.124213,0.259632,0.30793,0.180606,0.159884,0.257294,0.150733,0.217112,0.123917,0.184317,0.185335,0.0723291,0.258496,0.261744,0.203781,0.21382,0.207559,0.141867,0.193031,0.249101,0.115972,0.224568,0.246105,0.173026,0.200432,0.139785,0.197112,0.240478,0.156465,0.13108,0.256963,0.222798,0.172134,0.176789,0.0969345,0.202137,0.310405,0.280943,0.218161,0.0822373,0.202065,0.106739,0.0536053,0.0537737,0.15113,0.078016,0.0407233,0.0537355,0.319922,0.261724,0.211332,0.187731,0.233626,0.189559,0.0812887,0.0981146,0.064145,0.121913,0.0638699,0.104603,0.0663259,0.0762523,0.128736,0.109171,0.04411,0.066952,0.089609,0.0367455,0.13497,0.204393,0.295769,0.286691,0.347036,0.141729,0.263159,0.255956,0.200105,0.227491,0.29837,0.253509,0.177664,0.28365,0.264413,0.131761,0.160658,0.206239,0.19924,0.28689,0.236464,0.325148,0.115817,0.218052,0.223831,0.11528,0.194982,0.190993,0.281727,0.283218,0.249955,0.164638,0.224257,0.0935776,0.327622,0.225752,0.207791,0.0958756,0.0859274,0.316866,0.171683,0.158847,0.271275,0.071111,0.270604,0.101021,0.222548,0.175934,0.157274,0.215705,0.252796,0.205954,0.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}}
}}

Revision as of 16:57, 26 November 2012


Full id: C4771_medulloblastoma_parietal_gastrointestinal_temporal_duodenum_occipital_neuroblastoma



Phase1 CAGE Peaks

Hg19::chr8:73449511..73449521,+p5@KCNB2
Hg19::chr8:73449535..73449575,+p3@KCNB2
Hg19::chr8:73560820..73560822,+p@chr8:73560820..73560822
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
ciliated cell1.38e-073
ciliated epithelial cell1.38e-073
multi-ciliated epithelial cell1.38e-073
non-pigmented ciliary epithelial cell1.38e-073
Uber Anatomy
Ontology termp-valuen
neural tube2.37e-4956
neural rod2.37e-4956
future spinal cord2.37e-4956
neural keel2.37e-4956
central nervous system8.32e-4781
nervous system1.29e-4589
regional part of nervous system1.07e-4353
regional part of brain1.07e-4353
brain1.49e-4168
future brain1.49e-4168
regional part of forebrain2.15e-4141
forebrain2.15e-4141
anterior neural tube2.15e-4141
future forebrain2.15e-4141
neural plate2.76e-4182
presumptive neural plate2.76e-4182
neurectoderm7.54e-3986
regional part of cerebral cortex5.03e-3822
neocortex1.25e-3720
brain grey matter2.19e-3734
gray matter2.19e-3734
telencephalon4.19e-3734
pre-chordal neural plate1.19e-3661
cerebral hemisphere1.29e-3632
regional part of telencephalon2.94e-3332
cerebral cortex5.54e-3325
pallium5.54e-3325
ecto-epithelium4.95e-32104
adult organism1.01e-27114
structure with developmental contribution from neural crest6.00e-27132
ectoderm-derived structure4.04e-24171
ectoderm4.04e-24171
presumptive ectoderm4.04e-24171
organ system subdivision9.50e-24223
gyrus7.41e-166
anatomical cluster1.81e-14373
temporal lobe1.92e-136
organ part1.18e-12218
tube1.50e-11192
brainstem1.61e-106
posterior neural tube2.03e-0915
chordal neural plate2.03e-0915
multi-tissue structure3.95e-09342
frontal cortex4.12e-093
occipital lobe4.85e-095
parietal lobe8.58e-095
epithelium1.22e-08306
limbic system1.87e-085
cell layer1.93e-08309
pons3.09e-083
spinal cord6.19e-083
dorsal region element6.19e-083
dorsum6.19e-083
organ1.07e-07503
ciliary epithelium1.38e-073
ciliary body1.38e-073
anatomical conduit2.69e-07240


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.