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Coexpression cluster:C140: Difference between revisions

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|tf_chipseq_enrich=FOS#2353;31:2.21378265536291:1.58301408387071e-05:0.000370276389485719!GATA2#2624;39:3.94485982229052:4.17751574144885e-14:6.83848850346672e-12!POLR2A#5430;90:1.53389512611291:1.36592983118522e-08:1.0039151698744e-06
|tf_chipseq_enrich=FOS#2353;31:2.21378265536291:1.58301408387071e-05:0.000370276389485719!GATA2#2624;39:3.94485982229052:4.17751574144885e-14:6.83848850346672e-12!POLR2A#5430;90:1.53389512611291:1.36592983118522e-08:1.0039151698744e-06
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|tfbs_overrepresentation_for_novel_motifs=0.632393,2.2504,0.439676,0.0585226,0.0178055,0.0056967,0.585341,0.695601,2.01779,2.32816,0.164357,0.0777717,0.143763,0.35829,0.384433,0.164006,0.105015,0.271285,4.78653,1.5816,0.0061868,6.63835,0.329005,0.00634009,0.138082,0.202889,0.829462,1.46607,1.08958,0.530623,0.908466,0.130183,0.419718,2.40786,0.0376686,0.672376,0.458257,0.728978,0.453907,0.415666,0.250396,0.813946,2.50893,0.000533123,2.11415,0.294009,0.389958,0.38022,0.567417,0.702415,0.617841,1.1777,0.522085,0.749569,1.17611,1.06044,0.0800834,0.45021,2.39656,0.647225,0.369284,0.39606,0.248871,0.423683,0.661562,0.0694574,0.151915,0.397262,0.122771,0.278105,0.264755,0.283964,0.026757,0.107752,0.748843,1.55488,1.68642,0.0786036,0.120502,0.321127,0.0252848,0.421515,0.0636421,0.0344761,0.291,0.920804,0.518052,0.587961,0.455736,1.19965,0.205085,0.262282,0.0358336,0.00218664,0.121847,0.156035,0.525639,0.398752,0.270875,1.00896,0.175962,0.138409,1.06864,0.261552,0.1689,0.157127,0.097364,0.534574,0.339854,0.151211,1.29925,0.0444677,0.735811,1.10129,0.176841,0.162729,0.812173,0.683859,0.0682883,0.366268,0.339678,0.0447242,0.11762,0.29265,0.24461,0.959604,0.37109,0.960847,0.123643,0.551603,0.0760112,0.135295,0.130627,0.154597,0.610781,0.623703,0.0273067,0.485279,0.187477,0.880167,0.520251,0.166255,1.08168,0.174152,0.338748,0.848596,0.524287,0.733383,0.596732,0.567367,3.35544,0.0930362,0.0761523,0.60438,0.59568,0.299432,0.113264,0.0289443,0.138177,0.37178,0.165583,0.895189,0.530277,0.904229,0.0726814,0.0631745,4.81093,0.82,22.1673
}}
}}

Revision as of 13:34, 26 November 2012


Full id: C140_Renal_Endothelial_Hepatic_Lymphatic_heart_lung_spleen



Phase1 CAGE Peaks

Hg19::chr10:129785574..129785580,+p14@PTPRE
Hg19::chr10:3466752..3466759,-p@chr10:3466752..3466759
-
Hg19::chr10:88715509..88715533,+p@chr10:88715509..88715533
+
Hg19::chr10:88717312..88717335,-p2@MMRN2
Hg19::chr10:88717337..88717379,-p1@MMRN2
Hg19::chr10:88717384..88717401,-p3@MMRN2
Hg19::chr10:99655692..99655725,-p@chr10:99655692..99655725
-
Hg19::chr11:124632179..124632199,-p1@ESAM
Hg19::chr11:124761247..124761258,-p@chr11:124761247..124761258
-
Hg19::chr11:124767043..124767111,-p2@ROBO4
Hg19::chr11:124767693..124767774,-p1@ROBO4
Hg19::chr11:124767798..124767809,-p3@ROBO4
Hg19::chr12:52300721..52300741,+p1@ACVRL1
Hg19::chr12:52300746..52300751,+p10@ACVRL1
Hg19::chr12:52301175..52301188,+p4@ACVRL1
Hg19::chr12:52301280..52301299,+p2@ACVRL1
Hg19::chr12:53443945..53443959,+p4@TENC1
Hg19::chr12:54813229..54813273,-p3@ITGA5
Hg19::chr13:114462172..114462186,+p2@FAM70B
Hg19::chr13:114462193..114462251,+p1@FAM70B
Hg19::chr14:105943573..105943602,+p5@CRIP2
Hg19::chr14:38725228..38725236,-p5@CLEC14A
Hg19::chr14:38725249..38725254,-p6@CLEC14A
Hg19::chr14:38725257..38725276,-p2@CLEC14A
Hg19::chr14:38725279..38725304,-p1@CLEC14A
Hg19::chr14:38725573..38725605,-p3@CLEC14A
Hg19::chr14:38725646..38725681,-p4@CLEC14A
Hg19::chr15:41221536..41221539,+p1@DLL4
Hg19::chr16:2220346..2220365,+p@chr16:2220346..2220365
+
Hg19::chr16:2220383..2220402,+p@chr16:2220383..2220402
+
Hg19::chr16:66400533..66400545,+p2@CDH5
Hg19::chr16:66400553..66400565,+p3@CDH5
Hg19::chr16:66400578..66400600,+p1@CDH5
Hg19::chr16:66413317..66413328,+p1@AB385138
Hg19::chr16:66422312..66422316,+p@chr16:66422312..66422316
+
Hg19::chr16:66423348..66423366,+p@chr16:66423348..66423366
+
Hg19::chr17:47287749..47287777,+p2@ABI3
Hg19::chr17:47287786..47287797,+p4@ABI3
Hg19::chr17:62084108..62084111,-p5@ICAM2
Hg19::chr17:62084115..62084146,-p2@ICAM2
Hg19::chr17:62084241..62084253,-p3@ICAM2
Hg19::chr17:6926362..6926377,+p1@BCL6B
Hg19::chr17:6926381..6926392,+p2@BCL6B
Hg19::chr17:7758374..7758390,+p1@TMEM88
Hg19::chr17:80803529..80803573,+p1@AK296594
Hg19::chr17:8213539..8213566,+p1@ARHGEF15
Hg19::chr17:8214130..8214149,+p2@ARHGEF15
Hg19::chr17:8230085..8230130,+p@chr17:8230085..8230130
+
Hg19::chr19:13213399..13213414,-p6@LYL1
Hg19::chr19:17375541..17375588,-p1@USHBP1
Hg19::chr19:41985048..41985050,-p@chr19:41985048..41985050
-
Hg19::chr19:4639514..4639575,+p1@TNFAIP8L1
Hg19::chr19:47220191..47220198,-p14@PRKD2
Hg19::chr19:47220200..47220229,-p3@PRKD2
Hg19::chr19:47231612..47231624,-p@chr19:47231612..47231624
-
Hg19::chr19:49243813..49243823,-p5@RASIP1
Hg19::chr19:49243830..49243844,-p3@RASIP1
Hg19::chr19:49243845..49243873,-p2@RASIP1
Hg19::chr19:55598636..55598675,+p@chr19:55598636..55598675
+
Hg19::chr1:153581416..153581458,-p4@S100A16
Hg19::chr1:153581468..153581499,-p3@S100A16
Hg19::chr1:154474878..154474925,-p1@SHE
Hg19::chr1:155279483..155279532,+p4@FDPS
Hg19::chr1:208417309..208417348,-p5@PLXNA2
Hg19::chr1:21606013..21606059,-p5@ECE1
Hg19::chr1:21606082..21606114,-p7@ECE1
Hg19::chr1:21606132..21606156,-p9@ECE1
Hg19::chr1:21606171..21606188,-p10@ECE1
Hg19::chr1:32041957..32041990,+p3@TINAGL1
Hg19::chr1:43766619..43766635,+p3@TIE1
Hg19::chr1:43766642..43766667,+p2@TIE1
Hg19::chr1:43766668..43766696,+p1@TIE1
Hg19::chr1:6545502..6545548,-p2@PLEKHG5
Hg19::chr1:85930471..85930494,+p@chr1:85930471..85930494
+
Hg19::chr20:19867150..19867175,+p7@RIN2
Hg19::chr20:19867269..19867283,+p3@RIN2
Hg19::chr20:62680984..62680999,-p1@SOX18
Hg19::chr22:23648925..23648941,+p5@BCR
Hg19::chr22:39640974..39640994,-p1@PDGFB
Hg19::chr2:56412902..56412919,-p1@ENST00000432793
p1@uc010fca.1
Hg19::chr3:14852174..14852233,+p@chr3:14852174..14852233
+
Hg19::chr3:168959838..168959856,+p@chr3:168959838..168959856
+
Hg19::chr3:194406603..194406619,+p1@FAM43A
Hg19::chr3:43538305..43538325,-p@chr3:43538305..43538325
-
Hg19::chr3:50360165..50360183,-p2@HYAL2
Hg19::chr3:50360192..50360204,-p3@HYAL2
Hg19::chr3:58034268..58034295,+p@chr3:58034268..58034295
+
Hg19::chr4:55991752..55991770,-p1@KDR
Hg19::chr5:138842286..138842336,-p1@ECSCR
Hg19::chr5:141060389..141060439,-p3@ARAP3
Hg19::chr5:150019857..150019868,+p18@SYNPO
Hg19::chr5:150019871..150019935,+p4@SYNPO
Hg19::chr5:150019938..150019967,+p14@SYNPO
Hg19::chr5:34656569..34656588,+p7@RAI14
Hg19::chr6:12290586..12290600,+p1@EDN1
Hg19::chr6:148664333..148664338,-p@chr6:148664333..148664338
-
Hg19::chr6:32191791..32191818,-p3@NOTCH4
Hg19::chr6:7726323..7726348,+p1@BMP6
Hg19::chr7:150690812..150690817,+p10@NOS3
Hg19::chr7:150690837..150690856,+p2@NOS3
Hg19::chr7:150690857..150690878,+p1@NOS3
Hg19::chr7:39663061..39663072,+p6@RALA
Hg19::chr7:93551032..93551066,+p3@GNG11
Hg19::chr8:10588010..10588030,-p1@SOX7
Hg19::chr8:21924000..21924036,+p4@EPB49
Hg19::chr9:116263778..116263793,+p2@RGS3
Hg19::chr9:116263811..116263822,+p14@RGS3
Hg19::chr9:130524695..130524736,-p10@SH2D3C
Hg19::chr9:130533558..130533610,-p1@SH2D3C
Hg19::chr9:130609397..130609424,-p9@ENG
Hg19::chr9:130616888..130616899,-p5@ENG
Hg19::chr9:130616926..130616944,-p1@ENG
Hg19::chr9:139538947..139538969,-p@chr9:139538947..139538969
-
Hg19::chr9:139543390..139543404,+p@chr9:139543390..139543404
+
Hg19::chr9:139543445..139543462,+p@chr9:139543445..139543462
+
Hg19::chr9:139557360..139557376,+p1@EGFL7
Hg19::chr9:139563710..139563714,+p@chr9:139563710..139563714
+
Hg19::chr9:139606943..139606979,+p2@FAM69B
Hg19::chr9:139606983..139607035,+p1@FAM69B
Hg19::chr9:35909452..35909465,+p5@LOC158376
Hg19::chr9:35909478..35909495,+p1@LOC158376
Hg19::chrX:128781635..128781648,-p@chrX:128781635..128781648
-
Hg19::chrX:128781853..128781866,-p@chrX:128781853..128781866
-
Hg19::chrX:128782722..128782738,-p5@APLN
Hg19::chrX:128788923..128788942,-p1@APLN
Hg19::chrX:71299684..71299699,+p@chrX:71299684..71299699
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

p.valueFDRnGenesnPathwayName
1.23161703778041e-050.00779613584915002323Angiogenesis (Wikipathways):WP1539



Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0001525angiogenesis2.11374324114935e-10
GO:0048514blood vessel morphogenesis3.33452412540309e-10
GO:0048646anatomical structure formation3.33452412540309e-10
GO:0001568blood vessel development4.18728600634572e-10
GO:0001944vasculature development4.18728600634572e-10
GO:0009887organ morphogenesis1.54920920309376e-08
GO:0007165signal transduction6.78298039940112e-07
GO:0048513organ development6.78298039940112e-07
GO:0007154cell communication6.78298039940112e-07
GO:0048731system development3.1700273590176e-05
GO:0009653anatomical structure morphogenesis0.000175551122952142
GO:0007275multicellular organismal development0.000259341093388208
GO:0048856anatomical structure development0.000288362204070747
GO:0044459plasma membrane part0.00108525939425613
GO:0005515protein binding0.00161340307696319
GO:0016020membrane0.00254974465118234
GO:0032502developmental process0.00254974465118234
GO:0005886plasma membrane0.00287052046562877
GO:0008015blood circulation0.00287052046562877
GO:0003013circulatory system process0.00287052046562877
GO:0005085guanyl-nucleotide exchange factor activity0.00287052046562877
GO:0032501multicellular organismal process0.00287052046562877
GO:0030334regulation of cell migration0.00287052046562877
GO:0005088Ras guanyl-nucleotide exchange factor activity0.00300668146559652
GO:0001569patterning of blood vessels0.00309874167099624
GO:0051270regulation of cell motility0.00385109523932316
GO:0040012regulation of locomotion0.00420797208421217
GO:0040011locomotion0.00422711851243521
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway0.00459854589949203
GO:0001570vasculogenesis0.00713528780788853
GO:0004871signal transducer activity0.00739650586127434
GO:0060089molecular transducer activity0.00739650586127434
GO:0007242intracellular signaling cascade0.0115242194591448
GO:0030695GTPase regulator activity0.0115997662814792
GO:0035295tube development0.013033832245552
GO:0005887integral to plasma membrane0.013033832245552
GO:0050794regulation of cellular process0.013033832245552
GO:0009880embryonic pattern specification0.013033832245552
GO:0048754branching morphogenesis of a tube0.013033832245552
GO:0007166cell surface receptor linked signal transduction0.013033832245552
GO:0031226intrinsic to plasma membrane0.013033832245552
GO:0005102receptor binding0.0132932641457088
GO:0019199transmembrane receptor protein kinase activity0.0139364903259838
GO:0001763morphogenesis of a branching structure0.0148506915197131
GO:0007167enzyme linked receptor protein signaling pathway0.0148506915197131
GO:0051216cartilage development0.0148506915197131
GO:0048523negative regulation of cellular process0.0148506915197131
GO:0043179rhythmic excitation0.0148506915197131
GO:0032352positive regulation of hormone metabolic process0.0148506915197131
GO:0032346positive regulation of aldosterone metabolic process0.0148506915197131
GO:0030214hyaluronan catabolic process0.0148506915197131
GO:0032344regulation of aldosterone metabolic process0.0148506915197131
GO:0008212mineralocorticoid metabolic process0.0148506915197131
GO:0031583G-protein signaling, phospholipase D activating pathway0.0148506915197131
GO:0032341aldosterone metabolic process0.0148506915197131
GO:0031705bombesin receptor binding0.0148506915197131
GO:0032349positive regulation of aldosterone biosynthetic process0.0148506915197131
GO:0045602negative regulation of endothelial cell differentiation0.0148506915197131
GO:0031708endothelin B receptor binding0.0148506915197131
GO:0046886positive regulation of hormone biosynthetic process0.0148506915197131
GO:0032347regulation of aldosterone biosynthetic process0.0148506915197131
GO:0006705mineralocorticoid biosynthetic process0.0148506915197131
GO:0060024rhythmic synaptic transmission0.0148506915197131
GO:0031707endothelin A receptor binding0.0148506915197131
GO:0032342aldosterone biosynthetic process0.0148506915197131
GO:0005089Rho guanyl-nucleotide exchange factor activity0.0152219150871958
GO:0005178integrin binding0.0167492685695314
GO:0016337cell-cell adhesion0.0167617032908913
GO:0035023regulation of Rho protein signal transduction0.0167617032908913
GO:0048519negative regulation of biological process0.0167617032908913
GO:0005096GTPase activator activity0.0167617032908913
GO:0007264small GTPase mediated signal transduction0.0171055130606644
GO:0007611learning and/or memory0.0176838383971589
GO:0000267cell fraction0.019491218977117
GO:0007243protein kinase cascade0.020681995047378
GO:0050789regulation of biological process0.020681995047378
GO:0007219Notch signaling pathway0.020681995047378
GO:0007179transforming growth factor beta receptor signaling pathway0.020681995047378
GO:0006928cell motility0.020681995047378
GO:0051674localization of cell0.020681995047378
GO:0007266Rho protein signal transduction0.020681995047378
GO:0044425membrane part0.020681995047378
GO:0048522positive regulation of cellular process0.020681995047378
GO:0004161dimethylallyltranstransferase activity0.020681995047378
GO:0046885regulation of hormone biosynthetic process0.020681995047378
GO:0045601regulation of endothelial cell differentiation0.020681995047378
GO:0032350regulation of hormone metabolic process0.020681995047378
GO:0043266regulation of potassium ion transport0.020681995047378
GO:0016512endothelin-converting enzyme 1 activity0.020681995047378
GO:0043267negative regulation of potassium ion transport0.020681995047378
GO:0030818negative regulation of cAMP biosynthetic process0.020681995047378
GO:0004337geranyltranstransferase activity0.020681995047378
GO:0030815negative regulation of cAMP metabolic process0.020681995047378
GO:0022610biological adhesion0.020681995047378
GO:0007155cell adhesion0.020681995047378
GO:0008217regulation of blood pressure0.0208876090183414
GO:0019992diacylglycerol binding0.0237273639474397
GO:0006357regulation of transcription from RNA polymerase II promoter0.0244904002179798
GO:0048609reproductive process in a multicellular organism0.0245692223867628
GO:0032504multicellular organism reproduction0.0245692223867628
GO:0030054cell junction0.0249804018170239
GO:0035313wound healing, spreading of epidermal cells0.0260506721266188
GO:0051895negative regulation of focal adhesion formation0.0260506721266188
GO:0030800negative regulation of cyclic nucleotide metabolic process0.0260506721266188
GO:0051926negative regulation of calcium ion transport0.0260506721266188
GO:0030809negative regulation of nucleotide biosynthetic process0.0260506721266188
GO:0042474middle ear morphogenesis0.0260506721266188
GO:0050431transforming growth factor beta binding0.0260506721266188
GO:0017112Rab guanyl-nucleotide exchange factor activity0.0260506721266188
GO:0045940positive regulation of steroid metabolic process0.0260506721266188
GO:0030803negative regulation of cyclic nucleotide biosynthetic process0.0260506721266188
GO:0008047enzyme activator activity0.0277268203388958
GO:0048518positive regulation of biological process0.0284296971339626
GO:0008283cell proliferation0.0285356183144314
GO:0016477cell migration0.0285356183144314
GO:0048869cellular developmental process0.0285356183144314
GO:0030154cell differentiation0.0285356183144314
GO:0005625soluble fraction0.0285356183144314
GO:0031252leading edge0.0285356183144314
GO:0042127regulation of cell proliferation0.0287805204218956
GO:0005083small GTPase regulator activity0.0294031444630966
GO:0005509calcium ion binding0.0294096443542626
GO:0002028regulation of sodium ion transport0.0294096443542626
GO:0016361activin receptor activity, type I0.0294096443542626
GO:0043271negative regulation of ion transport0.0294096443542626
GO:0048662negative regulation of smooth muscle cell proliferation0.0294096443542626
GO:0007044cell-substrate junction assembly0.0294096443542626
GO:0051893regulation of focal adhesion formation0.0294096443542626
GO:0016511endothelin-converting enzyme activity0.0294096443542626
GO:0001542ovulation from ovarian follicle0.0294096443542626
GO:0030147natriuresis0.0294096443542626
GO:0009966regulation of signal transduction0.0334764827654863
GO:0035239tube morphogenesis0.0341296992268949
GO:0030728ovulation0.0341296992268949
GO:0031663lipopolysaccharide-mediated signaling pathway0.0341296992268949
GO:0005161platelet-derived growth factor receptor binding0.0341296992268949
GO:0030817regulation of cAMP biosynthetic process0.0341296992268949
GO:0003091renal water homeostasis0.0341296992268949
GO:0043204perikaryon0.0341296992268949
GO:0030146diuresis0.0341296992268949
GO:0050785advanced glycation end-product receptor activity0.0341296992268949
GO:0043086negative regulation of catalytic activity0.0345027212697935
GO:0006468protein amino acid phosphorylation0.0351613870136064
GO:0005923tight junction0.0353020665695773
GO:0006694steroid biosynthetic process0.0353020665695773
GO:0045941positive regulation of transcription0.0362924477264727
GO:0016021integral to membrane0.0362924477264727
GO:0006026aminoglycan catabolic process0.0362924477264727
GO:0043197dendritic spine0.0362924477264727
GO:0017002activin receptor activity0.0362924477264727
GO:0030802regulation of cyclic nucleotide biosynthetic process0.0362924477264727
GO:0051346negative regulation of hydrolase activity0.0362924477264727
GO:0030808regulation of nucleotide biosynthetic process0.0362924477264727
GO:0005025transforming growth factor beta receptor activity, type I0.0362924477264727
GO:0051482elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)0.0362924477264727
GO:0006027glycosaminoglycan catabolic process0.0362924477264727
GO:0045980negative regulation of nucleotide metabolic process0.0362924477264727
GO:0030814regulation of cAMP metabolic process0.0362924477264727
GO:0048185activin binding0.0362924477264727
GO:0065007biological regulation0.037269427936824
GO:0031224intrinsic to membrane0.037269427936824
GO:0045935positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.037269427936824
GO:0044464cell part0.0384039828222961
GO:0007610behavior0.038563865296694
GO:0032403protein complex binding0.0395517057274204
GO:0004517nitric-oxide synthase activity0.039806510300465
GO:0001953negative regulation of cell-matrix adhesion0.039806510300465
GO:0030799regulation of cyclic nucleotide metabolic process0.039806510300465
GO:0030104water homeostasis0.039806510300465
GO:0043296apical junction complex0.0398555597965433
GO:0009888tissue development0.0408373114722924
GO:0016327apicolateral plasma membrane0.040866500537183
GO:0042995cell projection0.0432736643684624
GO:0004714transmembrane receptor protein tyrosine kinase activity0.0433830832959671
GO:0018987osmoregulation0.0439011016156574
GO:0006793phosphorus metabolic process0.0470645470973383
GO:0006796phosphate metabolic process0.0470645470973383
GO:0019229regulation of vasoconstriction0.0477164577152317
GO:0003014renal system process0.0477164577152317
GO:0051899membrane depolarization0.0477164577152317
GO:0005112Notch binding0.0477164577152317



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
adult organism5.19e-57114
anatomical conduit6.94e-32240
tube2.67e-29192
anatomical cluster2.63e-27373
blood vessel endothelium1.78e-2518
endothelium1.78e-2518
cardiovascular system endothelium1.78e-2518
simple squamous epithelium1.43e-1922
neural tube3.68e-1956
neural rod3.68e-1956
future spinal cord3.68e-1956
neural keel3.68e-1956
splanchnic layer of lateral plate mesoderm2.76e-1883
vessel3.39e-1768
regional part of nervous system3.72e-1753
regional part of brain3.72e-1753
cell layer4.04e-17309
epithelium1.62e-16306
squamous epithelium2.08e-1625
structure with developmental contribution from neural crest3.96e-16132
circulatory system4.46e-16112
neural plate4.02e-1582
presumptive neural plate4.02e-1582
vasculature3.07e-1478
vascular system3.07e-1478
cardiovascular system3.91e-14109
neurectoderm7.70e-1486
regional part of forebrain8.26e-1441
forebrain8.26e-1441
anterior neural tube8.26e-1441
future forebrain8.26e-1441
endothelial tube1.47e-139
arterial system endothelium1.47e-139
endothelium of artery1.47e-139
epithelial tube1.48e-13117
epithelial tube open at both ends3.04e-1359
blood vessel3.04e-1359
blood vasculature3.04e-1359
vascular cord3.04e-1359
central nervous system9.91e-1381
brain1.81e-1268
future brain1.81e-1268
brain grey matter4.00e-1234
gray matter4.00e-1234
telencephalon6.07e-1234
compound organ3.50e-1168
multi-cellular organism9.06e-11656
regional part of telencephalon1.02e-1032
cerebral hemisphere1.06e-1032
anatomical system1.60e-10624
anatomical group1.93e-10625
multi-tissue structure2.07e-10342
nervous system2.28e-1089
ecto-epithelium4.04e-10104
primary circulatory organ1.45e-0927
organ system subdivision4.78e-09223
regional part of cerebral cortex5.32e-0922
neocortex7.17e-0920
pre-chordal neural plate2.33e-0861
embryonic structure2.97e-08564
lymphoid system3.34e-0810
germ layer4.25e-08560
germ layer / neural crest4.25e-08560
embryonic tissue4.25e-08560
presumptive structure4.25e-08560
germ layer / neural crest derived structure4.25e-08560
epiblast (generic)4.25e-08560
embryo5.86e-08592
developing anatomical structure7.09e-08581
vein7.36e-089
venous blood vessel7.36e-089
venous system7.36e-089
organ part1.26e-07218
cerebral cortex1.73e-0725
pallium1.73e-0725
heart3.77e-0724
primitive heart tube3.77e-0724
primary heart field3.77e-0724
anterior lateral plate mesoderm3.77e-0724
heart tube3.77e-0724
heart primordium3.77e-0724
cardiac mesoderm3.77e-0724
cardiogenic plate3.77e-0724
heart rudiment3.77e-0724


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
FOS#2353312.213782655362911.58301408387071e-050.000370276389485719
GATA2#2624393.944859822290524.17751574144885e-146.83848850346672e-12
POLR2A#5430901.533895126112911.36592983118522e-081.0039151698744e-06



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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