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Coexpression cluster:C4436: Difference between revisions

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|ontology_enrichment_celltype=
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!1.62e-38!115;UBERON:0005743!4.10e-29!86;UBERON:0001017!6.96e-29!82;UBERON:0001049!1.51e-26!57;UBERON:0005068!1.51e-26!57;UBERON:0006241!1.51e-26!57;UBERON:0007135!1.51e-26!57;UBERON:0000073!3.38e-26!94;UBERON:0001016!3.38e-26!94;UBERON:0000955!7.34e-24!69;UBERON:0006238!7.34e-24!69;UBERON:0003080!7.47e-24!42;UBERON:0002346!1.23e-23!90;UBERON:0002780!1.23e-23!41;UBERON:0001890!1.23e-23!41;UBERON:0006240!1.23e-23!41;UBERON:0003075!1.87e-23!86;UBERON:0007284!1.87e-23!86;UBERON:0002616!4.25e-22!59;UBERON:0001893!7.32e-21!34;UBERON:0002020!9.79e-21!34;UBERON:0003528!9.79e-21!34;UBERON:0002791!3.47e-20!33;UBERON:0001869!9.07e-20!32;UBERON:0000153!2.73e-19!129;UBERON:0007811!2.73e-19!129;UBERON:0003056!3.23e-19!61;UBERON:0000033!7.42e-19!123;UBERON:0000924!2.72e-16!173;UBERON:0006601!2.72e-16!173;UBERON:0000956!4.33e-16!25;UBERON:0000203!4.33e-16!25;UBERON:0004121!6.77e-16!169;UBERON:0002619!8.25e-16!22;UBERON:0000025!6.30e-15!194;UBERON:0004111!6.53e-15!241;UBERON:0001950!1.35e-14!20;UBERON:0000477!1.41e-13!286;UBERON:0000468!6.57e-12!659;UBERON:0000119!1.23e-11!312;UBERON:0000475!1.24e-11!365;UBERON:0000483!2.54e-11!309;UBERON:0000481!3.48e-09!347;UBERON:0000922!4.13e-09!612;UBERON:0000064!6.24e-09!219;UBERON:0000467!3.98e-08!625;UBERON:0000480!6.11e-08!626;UBERON:0000062!8.56e-08!511;UBERON:0002050!1.12e-07!605;UBERON:0005423!1.12e-07!605;UBERON:0000923!1.80e-07!604;UBERON:0005291!1.80e-07!604;UBERON:0006598!1.80e-07!604;UBERON:0002532!1.80e-07!604
|ontology_enrichment_uberon=UBERON:0007023!3.61e-46!114;UBERON:0001017!3.10e-31!81;UBERON:0001049!1.47e-30!56;UBERON:0005068!1.47e-30!56;UBERON:0006241!1.47e-30!56;UBERON:0007135!1.47e-30!56;UBERON:0001016!1.11e-29!89;UBERON:0000073!3.18e-28!53;UBERON:0002616!3.18e-28!53;UBERON:0011216!2.62e-26!223;UBERON:0000955!3.84e-26!68;UBERON:0006238!3.84e-26!68;UBERON:0002780!9.84e-26!41;UBERON:0001890!9.84e-26!41;UBERON:0003080!9.84e-26!41;UBERON:0006240!9.84e-26!41;UBERON:0001893!6.16e-24!34;UBERON:0003528!7.56e-24!34;UBERON:0002020!7.56e-24!34;UBERON:0002619!3.94e-23!22;UBERON:0001869!2.05e-22!32;UBERON:0003075!2.46e-22!82;UBERON:0007284!2.46e-22!82;UBERON:0002791!3.62e-22!32;UBERON:0001950!3.00e-21!20;UBERON:0002346!3.16e-21!86;UBERON:0000956!1.18e-20!25;UBERON:0000203!1.18e-20!25;UBERON:0010371!3.36e-18!104;UBERON:0004121!3.82e-18!171;UBERON:0000924!3.82e-18!171;UBERON:0006601!3.82e-18!171;UBERON:0000477!5.55e-18!373;UBERON:0003056!3.72e-17!61;UBERON:0010314!8.78e-17!132;UBERON:0000468!7.85e-11!656;UBERON:0000481!9.62e-10!342;UBERON:0004111!2.37e-09!240;UBERON:0000025!8.23e-09!192;UBERON:0000922!1.20e-08!592;UBERON:0001871!2.84e-08!6;UBERON:0000064!3.64e-08!218;UBERON:0000062!6.63e-08!503;UBERON:0000200!3.61e-07!6;UBERON:0005423!4.13e-07!581;UBERON:0000467!5.38e-07!624;UBERON:0000480!6.57e-07!625;UBERON:0002298!7.84e-07!6
|tf_chipseq_enrich=CTCF#10664;3:5.36025637307503:0.006492509252767:0.0280774813188295
|tf_chipseq_enrich=CTCF#10664;3:5.36025637307503:0.006492509252767:0.0280774813188295
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}}
}}

Revision as of 15:57, 19 October 2012


Full id: C4436_epididymis_migratory_Mast_breast_duodenum_temporal_parietal



Phase1 CAGE Peaks

Hg19::chr4:83483094..83483165,-p1@TMEM150C
Hg19::chr4:83483360..83483386,-p4@TMEM150C
Hg19::chr4:83483395..83483420,-p2@TMEM150C


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism3.61e-46114
central nervous system3.10e-3181
neural tube1.47e-3056
neural rod1.47e-3056
future spinal cord1.47e-3056
neural keel1.47e-3056
nervous system1.11e-2989
regional part of nervous system3.18e-2853
regional part of brain3.18e-2853
organ system subdivision2.62e-26223
brain3.84e-2668
future brain3.84e-2668
regional part of forebrain9.84e-2641
forebrain9.84e-2641
anterior neural tube9.84e-2641
future forebrain9.84e-2641
telencephalon6.16e-2434
brain grey matter7.56e-2434
gray matter7.56e-2434
regional part of cerebral cortex3.94e-2322
cerebral hemisphere2.05e-2232
neural plate2.46e-2282
presumptive neural plate2.46e-2282
regional part of telencephalon3.62e-2232
neocortex3.00e-2120
neurectoderm3.16e-2186
cerebral cortex1.18e-2025
pallium1.18e-2025
ecto-epithelium3.36e-18104
ectoderm-derived structure3.82e-18171
ectoderm3.82e-18171
presumptive ectoderm3.82e-18171
anatomical cluster5.55e-18373
pre-chordal neural plate3.72e-1761
structure with developmental contribution from neural crest8.78e-17132
multi-cellular organism7.85e-11656
multi-tissue structure9.62e-10342
anatomical conduit2.37e-09240
tube8.23e-09192
embryo1.20e-08592
temporal lobe2.84e-086
organ part3.64e-08218
organ6.63e-08503
gyrus3.61e-076
developing anatomical structure4.13e-07581
anatomical system5.38e-07624
anatomical group6.57e-07625
brainstem7.84e-076


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
CTCF#1066435.360256373075030.0064925092527670.0280774813188295



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.