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|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0514985917256918,0.0419359757688424,0,0,0.36326420548885,0.844083697856663,1.09250194148537,0.243590714728556,0.386949193329338,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.27847929887979,0.332974415283731,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0617533076901792,0,0,0,0,0,0,0,0,0,0,0,0.00951047361454448,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0370000010145431,0,0.0531716992363942,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0509235292940968,0,0.0829439327499637,0,0,0,0,0,0,0.0388988969149198,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0388749848471105,0.0269518943326477,0.0242538736058389,0,0,0,0,0,0,0,0,0,0,0.0352754493378881,0,0,0,0,0,0,0,0,0,0,0,0.0373735612902929,0.0760168881589905,0.0683709492064497,0.0820318188282719
|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0514985917256918,0.0419359757688424,0,0,0.36326420548885,0.844083697856663,1.09250194148537,0.243590714728556,0.386949193329338,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.27847929887979,0.332974415283731,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0617533076901792,0,0,0,0,0,0,0,0,0,0,0,0.00951047361454448,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0370000010145431,0,0.0531716992363942,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0509235292940968,0,0.0829439327499637,0,0,0,0,0,0,0.0388988969149198,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0388749848471105,0.0269518943326477,0.0242538736058389,0,0,0,0,0,0,0,0,0,0,0.0352754493378881,0,0,0,0,0,0,0,0,0,0,0,0.0373735612902929,0.0760168881589905,0.0683709492064497,0.0820318188282719
|gostat_on_MCL_coexpression=GO:0048523;negative regulation of cellular process;0.0188645246761372;21413,12803,20410,110648,50523,16334!GO:0048519;negative regulation of biological process;0.0188645246761372;21413,12803,20410,110648,50523,16334!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0350802163105439;21413,20410,16334!GO:0045892;negative regulation of transcription, DNA-dependent;0.0350802163105439;21413,20410,16334!GO:0050794;regulation of cellular process;0.0350802163105439;16870,101497,14726,16334,21413,12803,20410,110648,50523!GO:0042517;positive regulation of tyrosine phosphorylation of Stat3 protein;0.0350802163105439;12803!GO:0047372;acylglycerol lipase activity;0.0350802163105439;23945!GO:0007243;protein kinase cascade;0.0350802163105439;12803,20410,16334!GO:0042325;regulation of phosphorylation;0.0350802163105439;12803,16334!GO:0051174;regulation of phosphorus metabolic process;0.0350802163105439;12803,16334!GO:0019220;regulation of phosphate metabolic process;0.0350802163105439;12803,16334!GO:0016481;negative regulation of transcription;0.0350802163105439;21413,20410,16334!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0350802163105439;21413,20410,16334!GO:0050793;regulation of developmental process;0.0350802163105439;12803,110648,14726!GO:0009967;positive regulation of signal transduction;0.0350802163105439;12803,20410!GO:0046533;negative regulation of photoreceptor cell differentiation;0.0350802163105439;12803!GO:0001946;lymphangiogenesis;0.0350802163105439;14726!GO:0004084;branched-chain-amino-acid transaminase activity;0.0350802163105439;12035!GO:0009082;branched chain family amino acid biosynthetic process;0.0350802163105439;12035!GO:0046532;regulation of photoreceptor cell differentiation;0.0350802163105439;12803!GO:0050789;regulation of biological process;0.0350802163105439;16870,101497,14726,16334,21413,12803,20410,110648,50523!GO:0031324;negative regulation of cellular metabolic process;0.0416813114006787;21413,20410,16334!GO:0045596;negative regulation of cell differentiation;0.0475909014872444;12803,110648!
|gostat_on_MCL_coexpression=GO:0048523;negative regulation of cellular process;0.0188645246761372;21413,12803,20410,110648,50523,16334!GO:0048519;negative regulation of biological process;0.0188645246761372;21413,12803,20410,110648,50523,16334!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0350802163105439;21413,20410,16334!GO:0045892;negative regulation of transcription, DNA-dependent;0.0350802163105439;21413,20410,16334!GO:0050794;regulation of cellular process;0.0350802163105439;16870,101497,14726,16334,21413,12803,20410,110648,50523!GO:0042517;positive regulation of tyrosine phosphorylation of Stat3 protein;0.0350802163105439;12803!GO:0047372;acylglycerol lipase activity;0.0350802163105439;23945!GO:0007243;protein kinase cascade;0.0350802163105439;12803,20410,16334!GO:0042325;regulation of phosphorylation;0.0350802163105439;12803,16334!GO:0051174;regulation of phosphorus metabolic process;0.0350802163105439;12803,16334!GO:0019220;regulation of phosphate metabolic process;0.0350802163105439;12803,16334!GO:0016481;negative regulation of transcription;0.0350802163105439;21413,20410,16334!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0350802163105439;21413,20410,16334!GO:0050793;regulation of developmental process;0.0350802163105439;12803,110648,14726!GO:0009967;positive regulation of signal transduction;0.0350802163105439;12803,20410!GO:0046533;negative regulation of photoreceptor cell differentiation;0.0350802163105439;12803!GO:0001946;lymphangiogenesis;0.0350802163105439;14726!GO:0004084;branched-chain-amino-acid transaminase activity;0.0350802163105439;12035!GO:0009082;branched chain family amino acid biosynthetic process;0.0350802163105439;12035!GO:0046532;regulation of photoreceptor cell differentiation;0.0350802163105439;12803!GO:0050789;regulation of biological process;0.0350802163105439;16870,101497,14726,16334,21413,12803,20410,110648,50523!GO:0031324;negative regulation of cellular metabolic process;0.0416813114006787;21413,20410,16334!GO:0045596;negative regulation of cell differentiation;0.0475909014872444;12803,110648!
|ontology_enrichment_celltype=CL:0002453!3.02e-24!8;CL:0000333!3.18e-19!10;CL:0000095!3.18e-19!10;CL:0000243!3.18e-19!10;CL:0000123!3.18e-19!10;CL:0000125!3.18e-19!10;CL:0000030!3.18e-19!10;CL:0000339!3.18e-19!10;CL:0000128!5.37e-17!6;CL:0000126!5.37e-17!6;CL:0000127!5.37e-17!6;CL:0002605!2.55e-09!2;CL:0002604!2.55e-09!2;CL:0000878!5.24e-09!2;CL:0000129!5.24e-09!2
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000947!1.07e-08!4;UBERON:0001637!1.07e-08!4;UBERON:0004573!1.07e-08!4;UBERON:0003509!1.07e-08!4;UBERON:0004571!1.07e-08!4;UBERON:0010191!1.07e-08!4;UBERON:0004572!1.07e-08!4;UBERON:0000055!4.78e-07!5;UBERON:0007500!4.78e-07!5;UBERON:0001981!4.78e-07!5;UBERON:0002049!4.78e-07!5;UBERON:0007798!4.78e-07!5;UBERON:0004537!4.78e-07!5;UBERON:0006965!4.78e-07!5
}}
}}

Revision as of 16:57, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:102807862..102807882,-p4@C1ql1
Mm9::chr11:65982007..65982020,-p1@Dnahc9
Mm9::chr11:66340488..66340520,-p@chr11:66340488..66340520
-
Mm9::chr11:86449013..86449037,-p@chr11:86449013..86449037
-
Mm9::chr11:94103970..94103978,-p7@Wfikkn2
Mm9::chr12:86222392..86222395,-p@chr12:86222392..86222395
-
Mm9::chr14:58363487..58363492,-p2@Lats2
Mm9::chr14:70584674..70584706,-p@chr14:70584674..70584706
-
Mm9::chr14:70584860..70584873,-p@chr14:70584860..70584873
-
Mm9::chr14:70591272..70591278,-p@chr14:70591272..70591278
-
Mm9::chr14:70592471..70592519,-p@chr14:70592471..70592519
-
Mm9::chr14:70592525..70592545,-p@chr14:70592525..70592545
-
Mm9::chr14:70592586..70592593,-p@chr14:70592586..70592593
-
Mm9::chr14:70592626..70592638,-p@chr14:70592626..70592638
-
Mm9::chr14:70592673..70592699,-p@chr14:70592673..70592699
-
Mm9::chr14:70595792..70595803,-p@chr14:70595792..70595803
-
Mm9::chr14:70595804..70595816,-p@chr14:70595804..70595816
-
Mm9::chr14:70595852..70595906,-p@chr14:70595852..70595906
-
Mm9::chr16:15895800..15895814,-p@chr16:15895800..15895814
-
Mm9::chr16:15895817..15895825,-p@chr16:15895817..15895825
-
Mm9::chr16:15895858..15895888,-p@chr16:15895858..15895888
-
Mm9::chr16:65815522..65815531,+p7@Vgll3
Mm9::chr18:69681575..69681579,+p41@Tcf4
Mm9::chr19:12839908..12839933,-p2@Cntf
Mm9::chr19:12839937..12839975,-p1@Cntf
Mm9::chr19:17030554..17030565,+p5@Prune2
Mm9::chr19:57082667..57082674,-p9@Afap1l2
Mm9::chr19:8788884..8788904,-p11@Slc3a2
Mm9::chr1:135811214..135811246,+p@chr1:135811214..135811246
+
Mm9::chr1:135811313..135811319,-p@chr1:135811313..135811319
-
Mm9::chr1:135811453..135811463,-p@chr1:135811453..135811463
-
Mm9::chr1:135811547..135811559,-p@chr1:135811547..135811559
-
Mm9::chr1:135811595..135811619,-p@chr1:135811595..135811619
-
Mm9::chr1:135811969..135811982,-p@chr1:135811969..135811982
-
Mm9::chr1:135936805..135936816,+p@chr1:135936805..135936816
+
Mm9::chr1:135936829..135936839,+p@chr1:135936829..135936839
+
Mm9::chr1:135936851..135936856,+p@chr1:135936851..135936856
+
Mm9::chr1:135936902..135936908,+p@chr1:135936902..135936908
+
Mm9::chr1:135936916..135936937,+p@chr1:135936916..135936937
+
Mm9::chr1:135936937..135936962,-p@chr1:135936937..135936962
-
Mm9::chr1:135936949..135936959,+p@chr1:135936949..135936959
+
Mm9::chr1:135936966..135936975,-p@chr1:135936966..135936975
-
Mm9::chr1:135936977..135936983,+p@chr1:135936977..135936983
+
Mm9::chr1:135936996..135937007,+p@chr1:135936996..135937007
+
Mm9::chr1:135937391..135937415,+p@chr1:135937391..135937415
+
Mm9::chr1:135937446..135937472,+p@chr1:135937446..135937472
+
Mm9::chr1:135937506..135937517,+p@chr1:135937506..135937517
+
Mm9::chr1:135943255..135943275,+p@chr1:135943255..135943275
+
Mm9::chr1:163171792..163171811,-p@chr1:163171792..163171811
-
Mm9::chr1:169619239..169619257,+p4@Lmx1a
Mm9::chr1:169619683..169619694,+p1@Lmx1a
Mm9::chr1:72827387..72827393,-p@chr1:72827387..72827393
-
Mm9::chr1:72895689..72895698,-p@chr1:72895689..72895698
-
Mm9::chr1:72898995..72899006,+p@chr1:72898995..72899006
+
Mm9::chr2:38207200..38207210,+p13@Lhx2
Mm9::chr4:142857805..142857809,-p@chr4:142857805..142857809
-
Mm9::chr4:142858202..142858210,-p@chr4:142858202..142858210
-
Mm9::chr4:142863932..142863937,-p@chr4:142863932..142863937
-
Mm9::chr4:142889368..142889385,-p1@Pdpn
Mm9::chr4:142889401..142889414,-p2@Pdpn
Mm9::chr4:155213802..155213813,+p4@Mxra8
Mm9::chr5:23932660..23932685,+p6@Slc4a2
Mm9::chr5:23933325..23933336,+p11@Slc4a2
Mm9::chr5:92692680..92692701,-p@chr5:92692680..92692701
-
Mm9::chr6:140668711..140668721,-p@chr6:140668711..140668721
-
Mm9::chr6:144996025..144996043,-p7@Bcat1
Mm9::chr6:82983194..82983205,-p@chr6:82983194..82983205
-
Mm9::chr6:84135739..84135768,+p@chr6:84135739..84135768
+
Mm9::chr6:88777388..88777396,+p@chr6:88777388..88777396
+
Mm9::chr7:149885426..149885434,-p2@Ins2
Mm9::chr7:29157529..29157538,-p11@Plekhg2
Mm9::chr8:13483706..13483711,+p@chr8:13483706..13483711
+
Mm9::chr8:28089083..28089090,+p@chr8:28089083..28089090
+
Mm9::chr8:96676892..96676904,+p@chr8:96676892..96676904
+
Mm9::chr9:122478206..122478208,+p@chr9:122478206..122478208
+
Mm9::chr9:43915826..43915844,+p@chr9:43915826..43915844
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0048523negative regulation of cellular process0.0188645246761372
GO:0048519negative regulation of biological process0.0188645246761372
GO:0000122negative regulation of transcription from RNA polymerase II promoter0.0350802163105439
GO:0045892negative regulation of transcription, DNA-dependent0.0350802163105439
GO:0050794regulation of cellular process0.0350802163105439
GO:0042517positive regulation of tyrosine phosphorylation of Stat3 protein0.0350802163105439
GO:0047372acylglycerol lipase activity0.0350802163105439
GO:0007243protein kinase cascade0.0350802163105439
GO:0042325regulation of phosphorylation0.0350802163105439
GO:0051174regulation of phosphorus metabolic process0.0350802163105439
GO:0019220regulation of phosphate metabolic process0.0350802163105439
GO:0016481negative regulation of transcription0.0350802163105439
GO:0045934negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0350802163105439
GO:0050793regulation of developmental process0.0350802163105439
GO:0009967positive regulation of signal transduction0.0350802163105439
GO:0046533negative regulation of photoreceptor cell differentiation0.0350802163105439
GO:0001946lymphangiogenesis0.0350802163105439
GO:0004084branched-chain-amino-acid transaminase activity0.0350802163105439
GO:0009082branched chain family amino acid biosynthetic process0.0350802163105439
GO:0046532regulation of photoreceptor cell differentiation0.0350802163105439
GO:0050789regulation of biological process0.0350802163105439
GO:0031324negative regulation of cellular metabolic process0.0416813114006787
GO:0045596negative regulation of cell differentiation0.0475909014872444



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
aorta1.07e-084
artery1.07e-084
systemic artery1.07e-084
arterial blood vessel1.07e-084
systemic arterial system1.07e-084
aortic system1.07e-084
arterial system1.07e-084
vessel4.78e-075
epithelial tube open at both ends4.78e-075
blood vessel4.78e-075
vasculature4.78e-075
vascular system4.78e-075
blood vasculature4.78e-075
vascular cord4.78e-075


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}