UBERON:0002298: Difference between revisions
From FANTOM5_SSTAR
(Created page with "{{UBERON
|id=UBERON:0002298
|name=brainstem
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|def="The brainstem (or brain stem) is the lower part of the brain, adjoining and structurally continuous with the ...") |
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|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl | ||
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Revision as of 17:16, 15 June 2012
Name: | brainstem | ||
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Definition: | "The brainstem (or brain stem) is the lower part of the brain, adjoining and structurally continuous with the spinal cord. The brain stem provides the main motor and sensory innervation to the face and neck via the cranial nerves. Though small, this is an extremely important part of the brain as the nerve connections of the motor and sensory systems from the main part of the brain to the rest of the body pass through the brain stem. This includes the corticospinal tract (motor), the posterior column-medial lemniscus pathway (fine touch, vibration sensation and proprioception) and the spinothalamic tract (pain, temperature, itch and crude touch). The brain stem also plays an important role in the regulation of cardiac and respiratory function. It also regulates the central nervous system, and is pivotal in maintaining consciousness and regulating the sleep cycle. Some taxonomies describe the brain stem as the medulla oblongata (myelencephalon) and pons (part of metencephalon), whereas others include the midbrain (mesencephalon). [WP,unvetted]." [Wikipedia:Brainstem] | ||
Xrefs: |
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Synonyms: |
"brain stem" EXACT [ABA:BS] "truncus encephalicus" RELATED [BTO:0000146] | ||
Comments: | ZFA includes the tegmentum, MA the whole midbrain. Both include medulla oblongata. Here we make an overlaps link between midbrain and brainstem. Note that ABA states that cerebellum and brainstem are spatially disjoint. We do NOT include this axiom here, as it leads to multiple inconsistencies. This needs addressed in more detail. | ||
Alt_id: | UBERON:FMA_79876-MA_0000169 | ||
Subset: |
uberon_slim vertebrate_core |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0002616(regional part of brain) |
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part_of: | UBERON:0000955(brain) |
Children
part of: | UBERON:0000988 (pons),UBERON:0001896 (medulla oblongata),UBERON:0002275 (reticular formation),UBERON:0006331 (brainstem nucleus),UBERON:0015827 (brainstem reticular formation) |
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Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10033-101E6 (pons, adult, pool1)
- 10038-101F2 (medulla oblongata, adult, pool1)
- 10155-103A2 (medulla oblongata, adult, donor10252)
- 10165-103B3 (locus coeruleus, adult, donor10252)
- 10174-103C3 (medulla oblongata - adult, donor10196)
- 10182-103D2 (locus coeruleus - adult, donor10196)
- 10361-105F1 (medulla oblongata, newborn, donor10223)
- 10362-105F2 (locus coeruleus, newborn, donor10223)
- 10375-105G6 (locus coeruleus, adult, donor10258)
- 1396-42A3 (medulla oblongata, neonate N30)
... further results Mouse (Mus musculus)
- 10033-101E6 (pons, adult, pool1)
- 10038-101F2 (medulla oblongata, adult, pool1)
- 10155-103A2 (medulla oblongata, adult, donor10252)
- 10165-103B3 (locus coeruleus, adult, donor10252)
- 10174-103C3 (medulla oblongata - adult, donor10196)
- 10182-103D2 (locus coeruleus - adult, donor10196)
- 10361-105F1 (medulla oblongata, newborn, donor10223)
- 10362-105F2 (locus coeruleus, newborn, donor10223)
- 10375-105G6 (locus coeruleus, adult, donor10258)
- 1396-42A3 (medulla oblongata, neonate N30)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002298 (brainstem), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
P-value | FFCP | Short description |
---|---|---|
1.73e-118 | FFCP PHASE2:Hg19::chr12:72332618..72332632,+#_d66ad30c28141a4c845f221a2986ef7d | p1@TPH2 |
1.73e-118 | FFCP PHASE1:Hg19::chr12:72332618..72332632,+#_d66ad30c28141a4c845f221a2986ef7d | p1@TPH2 |
8.05e-117 | FFCP PHASE2:Hg19::chr4:117675601..117675614,+#_26af8d56ec17fc966bdd14c58c12aad5 | p@chr4:117675601..117675614, + |
8.05e-117 | FFCP PHASE1:Hg19::chr4:117675601..117675614,+#_26af8d56ec17fc966bdd14c58c12aad5 | p@chr4:117675601..117675614, + |
1.65e-116 | FFCP PHASE2:Hg19::chr2:69741832..69741847,-#_1ce75deb9f06e2af9d3128d156b22e91 | p@chr2:69741832..69741847, - |
1.65e-116 | FFCP PHASE1:Hg19::chr2:69741832..69741847,-#_1ce75deb9f06e2af9d3128d156b22e91 | p@chr2:69741832..69741847, - |
5.07e-102 | FFCP PHASE2:Hg19::chr9:128998376..128998387,-#_8f494f2b182dd0c1aae0f2bae2018a44 | p@chr9:128998376..128998387, - |
5.07e-102 | FFCP PHASE1:Hg19::chr9:128998376..128998387,-#_8f494f2b182dd0c1aae0f2bae2018a44 | p@chr9:128998376..128998387, - |
1.57e-98 | FFCP PHASE2:Hg19::chr2:72381655..72381673,-#_bea5de2b5ee97e65a786fdea7453c81e | p@chr2:72381655..72381673, - |
1.57e-98 | FFCP PHASE1:Hg19::chr2:72381655..72381673,-#_bea5de2b5ee97e65a786fdea7453c81e | p@chr2:72381655..72381673, - |
1.83e-98 | FFCP PHASE1:Hg19::chr5:126959224..126959239,+#_c04181094e2512171daa4dd2b2cfbb3c | p@chr5:126959224..126959239, + |
1.83e-98 | FFCP PHASE1:Hg19::chr16:49670005..49670020,-#_c04181094e2512171daa4dd2b2cfbb3c | p@chr16:49670005..49670020, - |
1.83e-98 | FFCP PHASE2:Hg19::chr5:126959224..126959239,+#_c04181094e2512171daa4dd2b2cfbb3c | p@chr5:126959224..126959239, + |
1.83e-98 | FFCP PHASE2:Hg19::chr16:49670005..49670020,-#_c04181094e2512171daa4dd2b2cfbb3c | p@chr16:49670005..49670020, - |
3.65e-98 | FFCP PHASE2:Hg19::chr16:290098..290109,+#_813d16cf0267b3f104241a123c3f51d6 | p13@ITFG3 |
3.65e-98 | FFCP PHASE1:Hg19::chr16:290098..290109,+#_813d16cf0267b3f104241a123c3f51d6 | p13@ITFG3 |
3.09e-91 | FFCP PHASE1:Hg19::chr11:20621148..20621166,+#_8178043de3e7d98d976ba929467e07d8 | p1@SLC6A5 |
3.09e-91 | FFCP PHASE2:Hg19::chr11:20621148..20621166,+#_8178043de3e7d98d976ba929467e07d8 | p1@SLC6A5 |
3.09e-91 | FFCP PHASE1:Hg19::chr15:60296481..60296492,+#_8178043de3e7d98d976ba929467e07d8 | p7@FOXB1 |
3.09e-91 | FFCP PHASE2:Hg19::chr15:60296481..60296492,+#_8178043de3e7d98d976ba929467e07d8 | p7@FOXB1 |
8.11e-91 | FFCP PHASE1:Hg19::chr15:79356984..79356998,-#_e97dcfb1b68795538757ef2464230176 | p8@RASGRF1 |
8.11e-91 | FFCP PHASE2:Hg19::chr15:79356984..79356998,-#_e97dcfb1b68795538757ef2464230176 | p8@RASGRF1 |
4.18e-87 | FFCP PHASE2:Hg19::chr2:25720324..25720333,-#_6f05ef33c9ee70d3660616c020973ea8 | p15@DTNB |
4.18e-87 | FFCP PHASE1:Hg19::chr2:25720324..25720333,-#_6f05ef33c9ee70d3660616c020973ea8 | p15@DTNB |
4.42e-84 | FFCP PHASE2:Hg19::chr12:26765770..26765792,-#_6d8e8da43032288fecb6bd22e7fe7651 | p@chr12:26765770..26765792, - |
4.42e-84 | FFCP PHASE1:Hg19::chr12:26765770..26765792,-#_6d8e8da43032288fecb6bd22e7fe7651 | p@chr12:26765770..26765792, - |
5.98e-82 | FFCP PHASE2:Hg19::chr14:62010202..62010207,-#_504247f84064adbd5cf0c54ed2baa110 | p@chr14:62010202..62010207, - |
5.98e-82 | FFCP PHASE1:Hg19::chr14:62010202..62010207,-#_504247f84064adbd5cf0c54ed2baa110 | p@chr14:62010202..62010207, - |
1.38e-81 | FFCP PHASE1:Hg19::chr2:179739649..179739660,-#_8c23122acc4efb7cbcd934ecb6e3af80 | p@chr2:179739649..179739660, - |
1.38e-81 | FFCP PHASE2:Hg19::chr2:179739649..179739660,-#_8c23122acc4efb7cbcd934ecb6e3af80 | p@chr2:179739649..179739660, - |
2.71e-79 | FFCP PHASE1:Hg19::chr5:151304948..151304984,-#_c1f753ce80d9148ee5880ebd57b17b4d | p@chr5:151304948..151304984, - |
2.71e-79 | FFCP PHASE2:Hg19::chr5:151304948..151304984,-#_c1f753ce80d9148ee5880ebd57b17b4d | p@chr5:151304948..151304984, - |
4.66e-79 | FFCP PHASE1:Hg19::chr4:79892974..79892983,+#_7c295724bc1a2dea737d9ee4d73aca55 | p8@LOC100505875 |
4.66e-79 | FFCP PHASE2:Hg19::chr4:79892974..79892983,+#_7c295724bc1a2dea737d9ee4d73aca55 | p8@LOC100505875 |
1.56e-78 | FFCP PHASE2:Hg19::chr18:74754861..74754870,+#_3c0d204eae8bb047f555d5fc42a2d6e7 | p@chr18:74754861..74754870, + |
1.56e-78 | FFCP PHASE1:Hg19::chr18:74754861..74754870,+#_3c0d204eae8bb047f555d5fc42a2d6e7 | p@chr18:74754861..74754870, + |
4.57e-78 | FFCP PHASE2:Hg19::chrX:145936111..145936120,+#_154075bf1804a5d8f464c29c75822c21 | p@chrX:145936111..145936120, + |
4.57e-78 | FFCP PHASE1:Hg19::chrX:145936111..145936120,+#_154075bf1804a5d8f464c29c75822c21 | p@chrX:145936111..145936120, + |
1.98e-77 | FFCP PHASE2:Hg19::chr14:105833371..105833383,+#_5897743b91f7f9d4925a4b9b131059db | p@chr14:105833371..105833383, + |
1.98e-77 | FFCP PHASE1:Hg19::chr14:105833371..105833383,+#_5897743b91f7f9d4925a4b9b131059db | p@chr14:105833371..105833383, + |
2.17e-75 | FFCP PHASE1:Hg19::chr5:151304987..151304998,-#_d080f732a55f5218d6bf96d995e7854d | p@chr5:151304987..151304998, - |
2.17e-75 | FFCP PHASE2:Hg19::chr5:151304987..151304998,-#_d080f732a55f5218d6bf96d995e7854d | p@chr5:151304987..151304998, - |
3.86e-75 | FFCP PHASE2:Hg19::chr2:234077664..234077672,+#_d61d5e5782fbd629850d1487ef2db2be | p@chr2:234077664..234077672, + |
3.86e-75 | FFCP PHASE1:Hg19::chr2:234077664..234077672,+#_d61d5e5782fbd629850d1487ef2db2be | p@chr2:234077664..234077672, + |
3.86e-75 | FFCP PHASE1:Hg19::chr5:150050170..150050182,+#_d61d5e5782fbd629850d1487ef2db2be | p@chr5:150050170..150050182, + |
3.86e-75 | FFCP PHASE2:Hg19::chr5:150050170..150050182,+#_d61d5e5782fbd629850d1487ef2db2be | p@chr5:150050170..150050182, + |
6.85e-75 | FFCP PHASE1:Hg19::chr11:30751827..30751838,+#_b24dabdffb401a06927acd2179048f55 | p@chr11:30751827..30751838, + |
6.85e-75 | FFCP PHASE2:Hg19::chr11:30751827..30751838,+#_b24dabdffb401a06927acd2179048f55 | p@chr11:30751827..30751838, + |
8.29e-75 | FFCP PHASE2:Hg19::chr1:155940355..155940366,-#_68f3f184de75f74ffe779ecfdec9e252 | p43@ARHGEF2 |
8.29e-75 | FFCP PHASE2:Hg19::chr15:79356834..79356842,-#_68f3f184de75f74ffe779ecfdec9e252 | p15@RASGRF1 |
8.29e-75 | FFCP PHASE1:Hg19::chr1:155940355..155940366,-#_68f3f184de75f74ffe779ecfdec9e252 | p43@ARHGEF2 |
8.29e-75 | FFCP PHASE1:Hg19::chr15:79356834..79356842,-#_68f3f184de75f74ffe779ecfdec9e252 | p15@RASGRF1 |
1.11e-74 | FFCP PHASE1:Hg19::chr14:91932629..91932652,-#_a8fc99f7f43a516ecea4dae34ea0cf20 | p14@SMEK1 |
1.11e-74 | FFCP PHASE2:Hg19::chr14:91932629..91932652,-#_a8fc99f7f43a516ecea4dae34ea0cf20 | p14@SMEK1 |
1.21e-74 | FFCP PHASE2:Hg19::chr17:65489258..65489261,-#_c403b3db3e18742fc3fdd35bf6599a6e | p@chr17:65489258..65489261, - |
1.21e-74 | FFCP PHASE1:Hg19::chr17:65489258..65489261,-#_c403b3db3e18742fc3fdd35bf6599a6e | p@chr17:65489258..65489261, - |
1.51e-74 | FFCP PHASE2:Hg19::chr17:42984370..42984375,-#_217d93db50b7a0ada83dc3a51d7c0406 | p42@GFAP |
1.51e-74 | FFCP PHASE1:Hg19::chr15:91447008..91447017,+#_217d93db50b7a0ada83dc3a51d7c0406 | p25@MAN2A2 |
1.51e-74 | FFCP PHASE1:Hg19::chr17:42984370..42984375,-#_217d93db50b7a0ada83dc3a51d7c0406 | p42@GFAP |
1.51e-74 | FFCP PHASE2:Hg19::chr15:91447008..91447017,+#_217d93db50b7a0ada83dc3a51d7c0406 | p25@MAN2A2 |
2.46e-74 | FFCP PHASE2:Hg19::chr7:147336227..147336236,+#_25438a5d0302e3b9b4dcef49493c3cbd | p18@CNTNAP2 |
2.46e-74 | FFCP PHASE1:Hg19::chr7:147336227..147336236,+#_25438a5d0302e3b9b4dcef49493c3cbd | p18@CNTNAP2 |
5.92e-74 | FFCP PHASE1:Hg19::chr14:105833352..105833361,+#_9f1a4f9dca51c66c5ebbb24de5941e20 | p@chr14:105833352..105833361, + |
5.92e-74 | FFCP PHASE2:Hg19::chr14:105833352..105833361,+#_9f1a4f9dca51c66c5ebbb24de5941e20 | p@chr14:105833352..105833361, + |
8.7e-74 | FFCP PHASE2:Hg19::chr5:77302570..77302586,+#_e3c630d4f2b9cb7764a72255ae43f5e7 | p@chr5:77302570..77302586, + |
8.7e-74 | FFCP PHASE1:Hg19::chr5:77302570..77302586,+#_e3c630d4f2b9cb7764a72255ae43f5e7 | p@chr5:77302570..77302586, + |
2.1e-73 | FFCP PHASE2:Hg19::chrX:106692537..106692551,+#_75cf0a4b97ef2d68fceb1026debbcf7c | p@chrX:106692537..106692551, + |
2.1e-73 | FFCP PHASE1:Hg19::chrX:106692537..106692551,+#_75cf0a4b97ef2d68fceb1026debbcf7c | p@chrX:106692537..106692551, + |
2.54e-70 | FFCP PHASE1:Hg19::chr2:25720404..25720435,-#_c119923ef128471785e1860e4c08d5ba | p8@DTNB |
2.54e-70 | FFCP PHASE2:Hg19::chr2:25720404..25720435,-#_c119923ef128471785e1860e4c08d5ba | p8@DTNB |
1.34e-69 | FFCP PHASE2:Hg19::chr15:79356860..79356874,-#_597b963268f97c661473ff8ad87d039a | p9@RASGRF1 |
1.34e-69 | FFCP PHASE1:Hg19::chr15:79356860..79356874,-#_597b963268f97c661473ff8ad87d039a | p9@RASGRF1 |
3.9e-69 | FFCP PHASE2:Hg19::chr5:152082403..152082408,+#_85d94ec934dab7823c474efef1b62692 | p@chr5:152082403..152082408, + |
3.9e-69 | FFCP PHASE1:Hg19::chr5:152082403..152082408,+#_85d94ec934dab7823c474efef1b62692 | p@chr5:152082403..152082408, + |
6.26e-69 | FFCP PHASE2:Hg19::chr21:18811205..18811216,+#_a72d345ba2e4217f16055127d73c6ab7 | p3@C21orf37 |
6.26e-69 | FFCP PHASE1:Hg19::chr21:18811205..18811216,+#_a72d345ba2e4217f16055127d73c6ab7 | p3@C21orf37 |
7.27e-69 | FFCP PHASE2:Hg19::chr4:34621389..34621413,+#_9cd6c582a9ff8384404c33cfdcbab05c | p@chr4:34621389..34621413, + |
7.27e-69 | FFCP PHASE1:Hg19::chr4:34621389..34621413,+#_9cd6c582a9ff8384404c33cfdcbab05c | p@chr4:34621389..34621413, + |
1.46e-68 | FFCP PHASE1:Hg19::chrX:16753203..16753238,+#_aa3378aac3944bb422a3da8fd63a1204 | p@chrX:16753203..16753238, + |
1.46e-68 | FFCP PHASE2:Hg19::chrX:16753203..16753238,+#_aa3378aac3944bb422a3da8fd63a1204 | p@chrX:16753203..16753238, + |
1.47e-66 | FFCP PHASE1:Hg19::chr15:93616900..93616918,-#_15d312fbf39ad5233a3208aade390686 | p6@RGMA |
1.47e-66 | FFCP PHASE2:Hg19::chr15:93616900..93616918,-#_15d312fbf39ad5233a3208aade390686 | p6@RGMA |
1.87e-66 | FFCP PHASE2:Hg19::chr18:5577640..5577652,-#_43eddf22ed52394d9aaed4c2c7fd540d | p14@EPB41L3 |
1.87e-66 | FFCP PHASE1:Hg19::chr18:5577640..5577652,-#_43eddf22ed52394d9aaed4c2c7fd540d | p14@EPB41L3 |
2.06e-66 | FFCP PHASE1:Hg19::chr2:25720352..25720388,-#_e880f46bf4e87ab966374e9c57c59655 | p7@DTNB |
2.06e-66 | FFCP PHASE2:Hg19::chr2:25720352..25720388,-#_e880f46bf4e87ab966374e9c57c59655 | p7@DTNB |
2.83e-66 | FFCP PHASE2:Hg19::chr6:132580699..132580702,+#_2a2041befc4eada1b7dd8cbc01329371 | p@chr6:132580699..132580702, + |
2.83e-66 | FFCP PHASE1:Hg19::chr6:132580699..132580702,+#_2a2041befc4eada1b7dd8cbc01329371 | p@chr6:132580699..132580702, + |
2.83e-66 | FFCP PHASE1:Hg19::chr11:3224990..3225000,-#_2a2041befc4eada1b7dd8cbc01329371 | p@chr11:3224990..3225000, - |
2.83e-66 | FFCP PHASE2:Hg19::chr5:35090057..35090065,-#_2a2041befc4eada1b7dd8cbc01329371 | p27@PRLR |
2.83e-66 | FFCP PHASE2:Hg19::chr4:117675642..117675654,+#_2a2041befc4eada1b7dd8cbc01329371 | p@chr4:117675642..117675654, + |
2.83e-66 | FFCP PHASE1:Hg19::chr6:56820018..56820029,+#_2a2041befc4eada1b7dd8cbc01329371 | p16@BEND6 |
2.83e-66 | FFCP PHASE2:Hg19::chr12:33592574..33592584,-#_2a2041befc4eada1b7dd8cbc01329371 | p6@SYT10 |
2.83e-66 | FFCP PHASE1:Hg19::chr5:35090057..35090065,-#_2a2041befc4eada1b7dd8cbc01329371 | p27@PRLR |
2.83e-66 | FFCP PHASE2:Hg19::chr2:237146889..237146895,-#_2a2041befc4eada1b7dd8cbc01329371 | p@chr2:237146889..237146895, - |
2.83e-66 | FFCP PHASE1:Hg19::chr2:237146889..237146895,-#_2a2041befc4eada1b7dd8cbc01329371 | p@chr2:237146889..237146895, - |
2.83e-66 | FFCP PHASE1:Hg19::chr5:35090318..35090324,-#_2a2041befc4eada1b7dd8cbc01329371 | p@chr5:35090318..35090324, - |
2.83e-66 | FFCP PHASE1:Hg19::chr12:33592574..33592584,-#_2a2041befc4eada1b7dd8cbc01329371 | p6@SYT10 |
2.83e-66 | FFCP PHASE2:Hg19::chr6:56820018..56820029,+#_2a2041befc4eada1b7dd8cbc01329371 | p16@BEND6 |
2.83e-66 | FFCP PHASE1:Hg19::chr12:44467410..44467418,+#_2a2041befc4eada1b7dd8cbc01329371 | p13@TMEM117 |