MCL coexpression mm9:392

Phase1 CAGE Peaks

	Short description
Mm9::chr10:61573809..61573820,-	p3@2010107G23Rik
Mm9::chr11:24058300..24058311,+	p@chr11:24058300..24058311 +
Mm9::chr11:70846402..70846415,-	p@chr11:70846402..70846415 -
Mm9::chr11:78311195..78311232,-	p2@Sarm1
Mm9::chr12:28019641..28019644,-	p@chr12:28019641..28019644 -
Mm9::chr14:65207115..65207126,+	p@chr14:65207115..65207126 +
Mm9::chr14:65207173..65207198,+	p@chr14:65207173..65207198 +
Mm9::chr14:65209241..65209263,+	p1@Mir124a-1
Mm9::chr17:56615930..56615940,-	p6@Ptprs
Mm9::chr18:25913004..25913008,+	p@chr18:25913004..25913008 +
Mm9::chr18:65742044..65742053,+	p11@Zfp532
Mm9::chr1:170361398..170361400,-	p@chr1:170361398..170361400 -
Mm9::chr2:158436393..158436401,-	p2@ENSMUST00000145773
Mm9::chr2:180627636..180627644,-	p@chr2:180627636..180627644 -
Mm9::chr4:45824178..45824182,-	p@chr4:45824178..45824182 -
Mm9::chr8:125944765..125944779,+	p@chr8:125944765..125944779 +
Mm9::chr9:21850877..21850881,-	p@chr9:21850877..21850881 -
Mm9::chr9:41388869..41388891,-	p@chr9:41388869..41388891 -
Mm9::chrX:45872717..45872735,+	p4@Rab33a

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0031315	extrinsic to mitochondrial outer membrane	0.0281871473182491
GO:0031312	extrinsic to organelle membrane	0.0281871473182491
GO:0009746	response to hexose stimulus	0.0450772013900306
GO:0009749	response to glucose stimulus	0.0450772013900306
GO:0009743	response to carbohydrate stimulus	0.0450772013900306

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
CNS neuron (sensu Vertebrata)	7.98e-25	23
neuroblast (sensu Vertebrata)	7.98e-25	23
neuron	1.25e-16	33
neuronal stem cell	1.25e-16	33
neuroblast	1.25e-16	33
electrically signaling cell	1.25e-16	33
electrically responsive cell	6.05e-13	39
electrically active cell	6.05e-13	39
neural cell	2.66e-12	43
ectodermal cell	7.45e-12	44
neurectodermal cell	7.45e-12	44
non-terminally differentiated cell	6.55e-10	49
neuron of cerebral cortex	9.65e-10	6

Uber Anatomy

Ontology term	p-value	n
gray matter	4.83e-32	34
neurectoderm	5.42e-30	64
neural plate	5.42e-30	64
presumptive neural plate	5.42e-30	64
regional part of nervous system	8.32e-30	54
central nervous system	2.80e-29	73
neural tube	3.80e-29	52
neural rod	3.80e-29	52
future spinal cord	3.80e-29	52
neural keel	3.80e-29	52
nervous system	4.12e-28	75
brain grey matter	7.81e-26	29
regional part of telencephalon	7.81e-26	29
telencephalon	7.81e-26	29
ectoderm-derived structure	7.57e-25	95
ectoderm	7.57e-25	95
presumptive ectoderm	7.57e-25	95
ecto-epithelium	1.34e-24	73
brain	9.52e-24	47
future brain	9.52e-24	47
pre-chordal neural plate	1.21e-23	49
regional part of brain	1.15e-22	46
anterior neural tube	1.47e-22	40
regional part of forebrain	8.93e-22	39
forebrain	8.93e-22	39
future forebrain	8.93e-22	39
cerebral cortex	5.38e-21	21
cerebral hemisphere	5.38e-21	21
pallium	5.38e-21	21
structure with developmental contribution from neural crest	9.40e-17	92
regional part of cerebral cortex	4.91e-16	17
occipital lobe	1.20e-12	10
visual cortex	1.20e-12	10
neocortex	1.20e-12	10
spinal cord	6.35e-08	6
dorsal region element	6.35e-08	6
dorsum	6.35e-08	6
regional part of spinal cord	2.36e-07	5
gray matter of spinal cord	2.36e-07	5
tube	4.04e-07	114
posterior neural tube	5.09e-07	12
chordal neural plate	5.09e-07	12

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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