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MCL coexpression mm9:1314: Difference between revisions

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{{MCL_coexpression_mm9
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1-dehydrogenase activity;0.00427327014737304;100198!GO:0004092;carnitine O-acetyltransferase activity;0.00427327014737304;12908!GO:0017057;6-phosphogluconolactonase activity;0.00569753744574322;100198!GO:0004345;glucose-6-phosphate dehydrogenase activity;0.00640955403186268;100198!GO:0016413;O-acetyltransferase activity;0.00683667033308187;12908!GO:0016406;carnitine O-acyltransferase activity;0.00854490141182739;12908!GO:0006098;pentose-phosphate shunt;0.00854490141182739;100198!GO:0006740;NADPH regeneration;0.00854490141182739;100198!GO:0005783;endoplasmic reticulum;0.0119405887772731;12908,100198!GO:0006739;NADP metabolic process;0.0119608953170559;100198!GO:0006769;nicotinamide metabolic process;0.0170823107874551;100198!GO:0019362;pyridine nucleotide metabolic process;0.0170823107874551;100198!GO:0008374;O-acyltransferase activity;0.0195183597364061;12908!GO:0006733;oxidoreduction coenzyme metabolic process;0.0195183597364061;100198!GO:0006767;water-soluble vitamin metabolic process;0.0221978731045733;100198!GO:0006007;glucose catabolic process;0.0243202733094806;100198!GO:0046365;monosaccharide catabolic process;0.0243202733094806;100198!GO:0019320;hexose catabolic process;0.0243202733094806;100198!GO:0046164;alcohol catabolic process;0.0243202733094806;100198!GO:0016407;acetyltransferase activity;0.0243202733094806;12908!GO:0006766;vitamin metabolic process;0.0251904777736148;100198!GO:0044275;cellular carbohydrate catabolic process;0.0255939662886466;100198!GO:0016052;carbohydrate catabolic process;0.0267023499321227;100198!GO:0042579;microbody;0.0300121230510755;12908!GO:0005777;peroxisome;0.0300121230510755;12908!GO:0006006;glucose metabolic process;0.0318013163867797;100198!GO:0004091;carboxylesterase activity;0.0328271196865096;100198!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0334754378610183;100198!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0349569205496525;100198!GO:0019318;hexose metabolic process;0.0368085097930655;100198!GO:0005996;monosaccharide metabolic process;0.0368085097930655;100198!GO:0005792;microsome;0.0388997222394472;100198!GO:0042598;vesicular fraction;0.0388997222394472;100198!GO:0006732;coenzyme metabolic process;0.0388997222394472;100198!GO:0006631;fatty acid metabolic process;0.0388997222394472;12908!GO:0008415;acyltransferase activity;0.0393149282099043;12908!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.0393149282099043;12908!GO:0016746;transferase activity, transferring acyl groups;0.0394691272818788;12908!GO:0009117;nucleotide metabolic process;0.0394691272818788;100198!GO:0051186;cofactor metabolic process;0.039751491500519;100198!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.0402259186969485;100198!GO:0032787;monocarboxylic acid metabolic process;0.0430914495999688;12908!GO:0044265;cellular macromolecule catabolic 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|gostat_on_MCL_coexpression=GO:0047936;glucose 1-dehydrogenase activity;0.00427327014737304;100198!GO:0004092;carnitine O-acetyltransferase activity;0.00427327014737304;12908!GO:0017057;6-phosphogluconolactonase activity;0.00569753744574322;100198!GO:0004345;glucose-6-phosphate dehydrogenase activity;0.00640955403186268;100198!GO:0016413;O-acetyltransferase activity;0.00683667033308187;12908!GO:0016406;carnitine O-acyltransferase activity;0.00854490141182739;12908!GO:0006098;pentose-phosphate shunt;0.00854490141182739;100198!GO:0006740;NADPH regeneration;0.00854490141182739;100198!GO:0005783;endoplasmic reticulum;0.0119405887772731;12908,100198!GO:0006739;NADP metabolic process;0.0119608953170559;100198!GO:0006769;nicotinamide metabolic process;0.0170823107874551;100198!GO:0019362;pyridine nucleotide metabolic process;0.0170823107874551;100198!GO:0008374;O-acyltransferase activity;0.0195183597364061;12908!GO:0006733;oxidoreduction coenzyme metabolic process;0.0195183597364061;100198!GO:0006767;water-soluble vitamin metabolic process;0.0221978731045733;100198!GO:0006007;glucose catabolic process;0.0243202733094806;100198!GO:0046365;monosaccharide catabolic process;0.0243202733094806;100198!GO:0019320;hexose catabolic process;0.0243202733094806;100198!GO:0046164;alcohol catabolic process;0.0243202733094806;100198!GO:0016407;acetyltransferase activity;0.0243202733094806;12908!GO:0006766;vitamin metabolic process;0.0251904777736148;100198!GO:0044275;cellular carbohydrate catabolic process;0.0255939662886466;100198!GO:0016052;carbohydrate catabolic process;0.0267023499321227;100198!GO:0042579;microbody;0.0300121230510755;12908!GO:0005777;peroxisome;0.0300121230510755;12908!GO:0006006;glucose metabolic process;0.0318013163867797;100198!GO:0004091;carboxylesterase activity;0.0328271196865096;100198!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0334754378610183;100198!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0349569205496525;100198!GO:0019318;hexose metabolic process;0.0368085097930655;100198!GO:0005996;monosaccharide metabolic process;0.0368085097930655;100198!GO:0005792;microsome;0.0388997222394472;100198!GO:0042598;vesicular fraction;0.0388997222394472;100198!GO:0006732;coenzyme metabolic process;0.0388997222394472;100198!GO:0006631;fatty acid metabolic process;0.0388997222394472;12908!GO:0008415;acyltransferase activity;0.0393149282099043;12908!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.0393149282099043;12908!GO:0016746;transferase activity, transferring acyl groups;0.0394691272818788;12908!GO:0009117;nucleotide metabolic process;0.0394691272818788;100198!GO:0051186;cofactor metabolic process;0.039751491500519;100198!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.0402259186969485;100198!GO:0032787;monocarboxylic acid metabolic process;0.0430914495999688;12908!GO:0044265;cellular macromolecule catabolic process;0.0444458513791493;100198!GO:0044262;cellular carbohydrate metabolic process;0.0475800590742983;100198!GO:0006066;alcohol metabolic process;0.0475800590742983;100198!GO:0044444;cytoplasmic part;0.0475800590742983;12908,100198!
}}

Latest revision as of 16:44, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:97548520..97548544,-p@chr11:97548520..97548544
-
Mm9::chr15:99548009..99548025,+p1@Gpd1
Mm9::chr2:30270822..30270888,-p3@Crat
Mm9::chr2:30270909..30270930,-p7@Crat
Mm9::chr2:30270938..30270949,-p8@Crat
Mm9::chr9:55258366..55258370,-p@chr9:55258366..55258370
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0047936glucose 1-dehydrogenase activity0.00427327014737304
GO:0004092carnitine O-acetyltransferase activity0.00427327014737304
GO:00170576-phosphogluconolactonase activity0.00569753744574322
GO:0004345glucose-6-phosphate dehydrogenase activity0.00640955403186268
GO:0016413O-acetyltransferase activity0.00683667033308187
GO:0016406carnitine O-acyltransferase activity0.00854490141182739
GO:0006098pentose-phosphate shunt0.00854490141182739
GO:0006740NADPH regeneration0.00854490141182739
GO:0005783endoplasmic reticulum0.0119405887772731
GO:0006739NADP metabolic process0.0119608953170559
GO:0006769nicotinamide metabolic process0.0170823107874551
GO:0019362pyridine nucleotide metabolic process0.0170823107874551
GO:0008374O-acyltransferase activity0.0195183597364061
GO:0006733oxidoreduction coenzyme metabolic process0.0195183597364061
GO:0006767water-soluble vitamin metabolic process0.0221978731045733
GO:0006007glucose catabolic process0.0243202733094806
GO:0046365monosaccharide catabolic process0.0243202733094806
GO:0019320hexose catabolic process0.0243202733094806
GO:0046164alcohol catabolic process0.0243202733094806
GO:0016407acetyltransferase activity0.0243202733094806
GO:0006766vitamin metabolic process0.0251904777736148
GO:0044275cellular carbohydrate catabolic process0.0255939662886466
GO:0016052carbohydrate catabolic process0.0267023499321227
GO:0042579microbody0.0300121230510755
GO:0005777peroxisome0.0300121230510755
GO:0006006glucose metabolic process0.0318013163867797
GO:0004091carboxylesterase activity0.0328271196865096
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor0.0334754378610183
GO:0016614oxidoreductase activity, acting on CH-OH group of donors0.0349569205496525
GO:0019318hexose metabolic process0.0368085097930655
GO:0005996monosaccharide metabolic process0.0368085097930655
GO:0005792microsome0.0388997222394472
GO:0042598vesicular fraction0.0388997222394472
GO:0006732coenzyme metabolic process0.0388997222394472
GO:0006631fatty acid metabolic process0.0388997222394472
GO:0008415acyltransferase activity0.0393149282099043
GO:0016747transferase activity, transferring groups other than amino-acyl groups0.0393149282099043
GO:0016746transferase activity, transferring acyl groups0.0394691272818788
GO:0009117nucleotide metabolic process0.0394691272818788
GO:0051186cofactor metabolic process0.039751491500519
GO:0055086nucleobase, nucleoside and nucleotide metabolic process0.0402259186969485
GO:0032787monocarboxylic acid metabolic process0.0430914495999688
GO:0044265cellular macromolecule catabolic process0.0444458513791493
GO:0044262cellular carbohydrate metabolic process0.0475800590742983
GO:0006066alcohol metabolic process0.0475800590742983
GO:0044444cytoplasmic part0.0475800590742983



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
intestine6.04e-1031
mucosa2.96e-0815
intestinal mucosa3.96e-0713
anatomical wall3.96e-0713
wall of intestine3.96e-0713
gastrointestinal system mucosa3.96e-0713


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.79006
MA0004.10.536396
MA0006.10.359699
MA0007.10.52077
MA0009.10.987341
MA0014.10.0315641
MA0017.14.72074
MA0019.10.800946
MA0024.10.942716
MA0025.11.22395
MA0027.12.64231
MA0028.10.370592
MA0029.10.920529
MA0030.10.927235
MA0031.10.890871
MA0038.10.686534
MA0040.11.00009
MA0041.10.457338
MA0042.10.443591
MA0043.11.08567
MA0046.11.02391
MA0048.10.486223
MA0050.10.57678
MA0051.10.695779
MA0052.11.00829
MA0055.10.212634
MA0056.10
MA0057.10.149949
MA0058.11.11298
MA0059.10.449345
MA0060.10.275911
MA0061.10.307097
MA0063.10
MA0066.10.675169
MA0067.11.33603
MA0068.10.911705
MA0069.11.00864
MA0070.10.998765
MA0071.10.575909
MA0072.10.990133
MA0073.10.0960184
MA0074.12.61015
MA0076.10.407465
MA0077.10.968053
MA0078.10.729877
MA0081.10.473489
MA0083.11.08487
MA0084.11.66561
MA0087.11.04109
MA0088.10.358337
MA0089.10
MA0090.10.500693
MA0091.10.55008
MA0092.10.501022
MA0093.10.988233
MA0095.10
MA0098.10
MA0100.10.626021
MA0101.10.458688
MA0103.10.398766
MA0105.10.57901
MA0106.10.737893
MA0107.10.392331
MA0108.20.824407
MA0109.10
MA0111.10.515457
MA0113.10.708789
MA0114.10.304661
MA0115.11.08851
MA0116.10.944657
MA0117.11.05576
MA0119.10.459301
MA0122.11.07591
MA0124.11.28237
MA0125.11.20757
MA0130.10
MA0131.10.796279
MA0132.10
MA0133.10
MA0135.11.1226
MA0136.10.658622
MA0139.10.682297
MA0140.10.625902
MA0141.11.89066
MA0142.10.876028
MA0143.10.725672
MA0144.10.307873
MA0145.10.119202
MA0146.10.353523
MA0147.10.320675
MA0148.10.553294
MA0149.10.464445
MA0062.20.204999
MA0035.20.630778
MA0039.24.12392
MA0138.21.85228
MA0002.20.689262
MA0137.20.416331
MA0104.20.261255
MA0047.20.685741
MA0112.20.37938
MA0065.20.380324
MA0150.13.28434
MA0151.10
MA0152.10.685852
MA0153.11.13945
MA0154.10.480757
MA0155.11.33283
MA0156.10.406559
MA0157.10.843181
MA0158.10
MA0159.10.881902
MA0160.10.556423
MA0161.10
MA0162.10.176524
MA0163.10.163321
MA0164.10.658997
MA0080.20.393257
MA0018.20.669032
MA0099.20.781628
MA0079.20.571196
MA0102.21.7182
MA0258.10.290587
MA0259.10.309517
MA0442.10
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