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MCL coexpression mm9:1071: Difference between revisions

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{{MCL_coexpression_mm9
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phosphorylase activity;0.0488854428731276;110095!GO:0004645;phosphorylase activity;0.0488854428731276;110095!GO:0005579;membrane attack complex;0.0488854428731276;15139!GO:0006957;complement activation, alternative pathway;0.0488854428731276;15139!GO:0010092;specification of organ identity;0.0488854428731276;14164!GO:0001759;induction of an organ;0.0488854428731276;14164!GO:0031128;induction;0.0488854428731276;14164!GO:0045168;cell-cell signaling during cell fate commitment;0.0488854428731276;14164!GO:0050679;positive regulation of epithelial cell proliferation;0.0488854428731276;14164!|ontology_enrichment_celltype=|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0002048!1.51e-14!14;UBERON:0000117!1.51e-14!14;UBERON:0000171!1.51e-14!14;UBERON:0000170!1.51e-14!14;UBERON:0005597!1.51e-14!14;UBERON:0000118!1.51e-14!14;UBERON:0009569!3.01e-14!66;UBERON:0005177!3.80e-13!79;UBERON:0005153!8.34e-13!17;UBERON:0002107!5.85e-12!22;UBERON:0007499!5.85e-12!22;UBERON:0006925!5.85e-12!22;UBERON:0009497!5.85e-12!22;UBERON:0000015!5.85e-12!22;UBERON:0002423!5.85e-12!22;UBERON:0006235!5.85e-12!22;UBERON:0008835!5.85e-12!22;UBERON:0003894!5.85e-12!22;UBERON:0004161!5.85e-12!22;UBERON:0008836!5.85e-12!22;UBERON:0000466!1.07e-11!79;UBERON:0005178!3.21e-11!17;UBERON:0005181!3.21e-11!17;UBERON:0002224!3.21e-11!17;UBERON:0000915!3.21e-11!17;UBERON:0008947!3.21e-11!17;UBERON:0003258!3.21e-11!17;UBERON:0009854!3.26e-11!23;UBERON:0009856!3.26e-11!23;UBERON:0002365!3.46e-11!25;UBERON:0002330!3.46e-11!25;UBERON:0002100!7.68e-11!90;UBERON:0005157!3.31e-10!20;UBERON:0005911!3.32e-09!69;UBERON:0001041!1.49e-08!80|tfbs_overrepresentation_for_novel_motifs=1.11639,0.161863,0.411716,0.480627,0.299217,0.495263,0.587291,0.594722,0.215218,0.219671,0.542749,1.40872,0.206435,0.599731,0.315771,0,0.795315,0.291368,0.561256,0.731589,0.978328,0.08187,0.598814,0.80655,0.419327,0.62766,1.0368,0.516511,0.344372,0.446946,0.50223,0.897561,0.289148,0.166577,0.316253,0.248902,0.279977,0.57142,0.717242,0.230656,0.800988,0.507468,0.54842,0.317766,0.115244,0.469348,0.714592,0.532496,1.25414,0.347313,0.777641,0.654933,1.3744,1.04034,1.0579,0.606984,0.937475,0.56214,0.176152,0.604914,0.877332,0.664501,0.642748,0.766235,0.618279,0.807219,1.19497,1.54543,0.872612,1.39786,0.392734,0.608073,0.0869413,1.09164,0.17012,0.936963,0.498755,0.703064,2.00003,0.378988,0.212973,0.812889,0.663039,0.200155,0.975495,0.0369809,0.042613,0.447265,0.719558,1.70793,1.26498,0.980512,0.910485,0.305079,0.254625,0.668513,1.11365,0.913319,0.71485,0.127063,0.7665,0.897279,1.02279,0.778243,0.777175,0.507021,0.837607,0.528416,0.383871,0.376549,0.430942,1.02459,0.380122,0.547992,1.27206,0.293461,0.187586,0.484437,0.796633,0.276329,1.09707,0.745011,0.629509,0.702145,1.32639,0.863723,0.595563,0.903645,1.19345,2.28972,1.00568,0.473246,1.16374,1.50487,1.29374,0.979575,0.446555,0.508896,1.24438,2.07659,1.67603,1.19971,0.641722,0.908128,0.770616,0.507927,0.717753,2.03691,0.448938,0.300961,0.452587,0.0736236,1.04192,0.243291,0.619892,1.12411,0.655955,0.327731,1.11101,0.446272,1.25393,0.974632,0.864173,0.428662,0.767269,0.612377,0.278874,0.573477,0.0206035|tfbs_overrepresentation_jaspar=MA0003.1;0.00513025,MA0004.1;0.481116,MA0006.1;0.311391,MA0007.1;0.465969,MA0009.1;0.92425,MA0014.1;0.0886247,MA0017.1;0.89657,MA0019.1;0.740036,MA0024.1;0.880057,MA0025.1;1.15921,MA0027.1;2.57545,MA0028.1;0.321735,MA0029.1;0.858105,MA0030.1;0.864739,MA0031.1;0.828781,MA0038.1;0.62758,MA0040.1;0.936879,MA0041.1;0.404721,MA0042.1;0.391504,MA0043.1;1.02178,MA0046.1;0.960497,MA0048.1;0.40238,MA0050.1;0.520357,MA0051.1;0.636645,MA0052.1;0.945011,MA0055.1;0.0406078,MA0056.1;0,MA0057.1;0.117936,MA0058.1;0.384683,MA0059.1;0.397033,MA0060.1;0.232592,MA0061.1;0.261749,MA0063.1;0,MA0066.1;0.616444,MA0067.1;1.27078,MA0068.1;0.121435,MA0069.1;0.945354,MA0070.1;0.93557,MA0071.1;0.519509,MA0072.1;0.927016,MA0073.1;0.00782298,MA0074.1;0.580087,MA0076.1;0.356883,MA0077.1;0.905143,MA0078.1;0.670113,MA0081.1;0.420276,MA0083.1;1.02098,MA0084.1;1.59945,MA0087.1;0.977537,MA0088.1;0.0841779,MA0089.1;0,MA0090.1;0.446539,MA0091.1;0.494398,MA0092.1;0.446857,MA0093.1;0.329976,MA0095.1;0,MA0098.1;0,MA0100.1;0.568369,MA0101.1;0.406019,MA0103.1;0.920496,MA0105.1;0.162418,MA0106.1;0.677988,MA0107.1;0.342432,MA0108.2;0.763162,MA0109.1;0,MA0111.1;1.16549,MA0113.1;0.649407,MA0114.1;0.719313,MA0115.1;1.0246,MA0116.1;1.51389,MA0117.1;0.992087,MA0119.1;1.84721,MA0122.1;1.01209,MA0124.1;1.21735,MA0125.1;1.14291,MA0130.1;0,MA0131.1;0.735438,MA0132.1;0,MA0133.1;0,MA0135.1;1.05845,MA0136.1;0.600242,MA0139.1;0.202522,MA0140.1;0.568252,MA0141.1;0.964041,MA0142.1;0.814115,MA0143.1;0.665982,MA0144.1;0.72625,MA0145.1;0.304732,MA0146.1;0.0256827,MA0147.1;0.274511,MA0148.1;0.49752,MA0149.1;0.411562,MA0062.2;0.167299,MA0035.2;0.573016,MA0039.2;0.014361,MA0138.2;0.727395,MA0002.2;0.205289,MA0137.2;0.365364,MA0104.2;0.218974,MA0047.2;0.626803,MA0112.2;0.0910939,MA0065.2;0.0914071,MA0150.1;0.465855,MA0151.1;0,MA0152.1;0.626912,MA0153.1;1.07519,MA0154.1;0.126143,MA0155.1;0.336768,MA0156.1;0.356017,MA0157.1;0.781683,MA0158.1;0,MA0159.1;0.776527,MA0160.1;0.50056,MA0161.1;0,MA0162.1;0.0312493,MA0163.1;0.116706,MA0164.1;0.600609,MA0080.2;0.343316,MA0018.2;0.610433,MA0099.2;0.721008,MA0079.2;0.0190804,MA0102.2;1.65195,MA0258.1;0.246285,MA0259.1;0.26402,MA0442.1;0}}
|coexpression_dpi_cluster_scores_mean=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.602321337425567,0,0,0.0264320139403867,0.0324901512315966,0,0,0.0121063835118862,0.0387820850300377,0.0392685738001133,0,0,0,0,0.031486549049326,0.0178081726676554,0.0327706697775275,0,0,0,0,0,0,0.0253040915268141,0.0114538228913639,0.0193997456826331,0,0.0346894162796295,0,0.0220459046144868,0.00812852549815554,0,0,0,0,0,0.103444583577593,0.0580045314789503,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0155890123844326,0,0,0,0,0,0.0141104805246217,0.0254862981748971,0,0.00543126050829464,0.0260149254075316,0.0305521939371317,0,0.0498764304771215,0,0.0155451974740733,0,0,0,0.132313640704035,0.778858271858039,0.702731031433469,1.12967358713021,1.21548591161453,1.18186081573714,0.803060894234123,0,0,0,0,0,0,0,0,0.0350760440632737,0,1.06670338212845,0,0.0869305220429631,0.0326997654996974,0.103187721458617,0.127107051639773,0.0697458223928827,0.084320659985212,0.102160544306581,0.096118498716417,0.0675205048895342,0,0,0,0,0.195840222959386,0,0,0,0,0,0,0.00865982409663879,0,0,0.00994330047383347,0,0,0.0246043272384373,0.0235353075565066,0.0421203621862259,0.0769464773570604,0.0948871011030624,0.0310917747884837,0.0234706587802934,0.0102721247630179,0.142414306049704,0.0348765225106857,0.00747898303001363,0.0162138861467265,0.0544212570900722,0.0222401288824406,0.0199022967846146,0,0.0225538710535566,0.0528542580092921,0.0370774648096114,0.0298290069520811,0,0,0,0,0.037442242660808,0.013071466002467,0.0205442423395938,0.0545201892572772,0.0360197696067843,0.0324988101602044,0.0366652340998774,0.140303209148522,0.00685170394538421,0,0,0.0189948906788237,0.0243796200359558,0.0246284718836836,0.0802038738025588,0,0,0,0.0263399146553961,0,0.0259126084081982,0.0150408442965713,0,0.0124579343678563,0.0351050444477131,0.0240933337853147,0.00945909795821856,0.0644061261571984,0.118207783230545,0.0425288664409087,0.0397833803115281,0.0693099356712104,0.0588833799425278,0.0107751062598479,0.0402770333532301,0.0468261834920764,0.0326983152133393,0.0203371046148981,0.0571214904565279,0.105357651895911,0.105254700702589,0.164511731657261,0.100978048212708,1.23523892308524,0.200687245681753,0.262311172024727,0.283369797900445,0.33466568928547,0.362680948810627,0.423643699460412,0.596256123148351,0.498178203764006,0.735997875728948,0.968095462062793,1.01001300680437,1.12072738949739,1.06774083771061,1.06649188358202,1.01300452244318,1.20854673271932,0.058628222362842,0.310290889068596,0.371267955873469,0.743993665448069,1.10021415785172,1.25564470790387,1.11526221551738,1.11928600404454,1.07575721478357,1.08834505969374,1.24888149849234,1.18657862920843,1.25743565542012,0,0,0.0673055224051427,0.0763788281069296,0.0652075483864608,0.018694206903127,0,0.0279336153314395,0.017013366563148,0,0,0,0,0,0.0210882581395,0.0285564935279951,0,0,0.0635414882910721,0.0367215073759084,0.0404898082846472,0.28103851090358,0,0.076278225709054,0.0491652412829263,0.0975267557309102,0.0483852852233394,0.10354290770595,0.0543716385051575,0.156606290884654,0.0785171162732424,0.0584116509054277,0,0,0.079852060602005,0,0.025872860163288,0.0341817718435431,0.0264663762282653,0.026591213892654,0.0094511106393726,0.0459956480346493,0.0130787852285702,0.0119203488312297,0.345040670324808,0.122675568193496,0.0245069970873399,0.0331142140584308,0.071193726111198,0.098845621017013,0.0284957714045469,0.113953638860417,0,0.0116409430100481,0.010541376779981,0.0198358510243387,0,0,0,0,0,0,0.0273306686019816,0.108295935708803,0.0619901862920263,0.0452351924571873,0.0674458660235357,0.231771865835513,0.391705520947655,0.096687796819815,0.028601440966652,0.236107123712921,0,0.0229904831383006,0,0.0203816744393609,0.0150729763318407,0.0180610900712751,0.00688457812232989,0.168248487365904,0.0169694815576066,0.0134251642233548,0,0.0170370798845866,0.0368420964652019,0.115419662360918,0.114454418661294,0.099086105094297,0.0943587295930099,0.0848184133580913,0.0610046101727506,0.0401053185295183,0.0540162129355033,0.0432600483639696,0.0110481842439249,0.0243674886612503,0.0255059898107916,0.0380353379990312,0,0,0,0.207309206165054,0,0.0967678348054964,0.0572438658491471,0.384327573741297,0,0,0,0,0,0,0,0,0,0,0.0168175155572363,0.0364002433182059,0.103096258125721,0.241295009759511,0.158520580599308,0.246600045167794,0.403274329441009,0.37944507747022,0.380506384466819,0.370762550199769,0.4135479485767,0.384241086549246,0.379382507029912,0.394157684546078,0.390329564079815,0.342088306488951,0.367867034211218,0.425482807270508,0.388899795085365,0.386244535067051,0.397709544648828,0.394722392701998,0.40549637257497,0.393154373566025,0.375844967112731,0.386831307071853,0.317028640575634,0.38413817846912,0.409026201864127,0.44052462987674,0.407718888028024,0.397243666774203,0.35176462624816,0.365548240476761,0.359322253114815,0.0389751078070841,0.381672860613946,0.414611046691256,0.0725961446573431,0.127799117553454,0.0407125613869914
|gostat_on_MCL_coexpression=GO:0008184;glycogen phosphorylase activity;0.0488854428731276;110095!GO:0004645;phosphorylase activity;0.0488854428731276;110095!GO:0005579;membrane attack complex;0.0488854428731276;15139!GO:0006957;complement activation, alternative pathway;0.0488854428731276;15139!GO:0010092;specification of organ identity;0.0488854428731276;14164!GO:0001759;induction of an organ;0.0488854428731276;14164!GO:0031128;induction;0.0488854428731276;14164!GO:0045168;cell-cell signaling during cell fate commitment;0.0488854428731276;14164!GO:0050679;positive regulation of epithelial cell proliferation;0.0488854428731276;14164!
}}

Latest revision as of 16:20, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:3931609..3931617,+p3@Sec14l4
Mm9::chr12:71332401..71332444,-p2@Pygl
Mm9::chr16:34807311..34807395,+p@chr16:34807311..34807395
+
Mm9::chr18:39026661..39026670,-p10@Fgf1
Mm9::chr18:39026712..39026728,-p2@Fgf1
Mm9::chr18:39026735..39026746,-p8@Fgf1
Mm9::chr2:34916923..34916939,-p1@Hc


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0008184glycogen phosphorylase activity0.0488854428731276
GO:0004645phosphorylase activity0.0488854428731276
GO:0005579membrane attack complex0.0488854428731276
GO:0006957complement activation, alternative pathway0.0488854428731276
GO:0010092specification of organ identity0.0488854428731276
GO:0001759induction of an organ0.0488854428731276
GO:0031128induction0.0488854428731276
GO:0045168cell-cell signaling during cell fate commitment0.0488854428731276
GO:0050679positive regulation of epithelial cell proliferation0.0488854428731276



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
lung1.51e-1414
respiratory tube1.51e-1414
respiration organ1.51e-1414
pair of lungs1.51e-1414
lung primordium1.51e-1414
lung bud1.51e-1414
subdivision of trunk3.01e-1466
trunk region element3.80e-1379
epithelial bud8.34e-1317
liver5.85e-1222
epithelial sac5.85e-1222
digestive gland5.85e-1222
epithelium of foregut-midgut junction5.85e-1222
anatomical boundary5.85e-1222
hepatobiliary system5.85e-1222
foregut-midgut junction5.85e-1222
hepatic diverticulum5.85e-1222
liver primordium5.85e-1222
septum transversum5.85e-1222
liver bud5.85e-1222
immaterial anatomical entity1.07e-1179
thoracic cavity element3.21e-1117
thoracic segment organ3.21e-1117
thoracic cavity3.21e-1117
thoracic segment of trunk3.21e-1117
respiratory primordium3.21e-1117
endoderm of foregut3.21e-1117
digestive tract diverticulum3.26e-1123
sac3.26e-1123
exocrine gland3.46e-1125
exocrine system3.46e-1125
trunk7.68e-1190
epithelial fold3.31e-1020
endo-epithelium3.32e-0969
foregut1.49e-0880


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.00513025
MA0004.10.481116
MA0006.10.311391
MA0007.10.465969
MA0009.10.92425
MA0014.10.0886247
MA0017.10.89657
MA0019.10.740036
MA0024.10.880057
MA0025.11.15921
MA0027.12.57545
MA0028.10.321735
MA0029.10.858105
MA0030.10.864739
MA0031.10.828781
MA0038.10.62758
MA0040.10.936879
MA0041.10.404721
MA0042.10.391504
MA0043.11.02178
MA0046.10.960497
MA0048.10.40238
MA0050.10.520357
MA0051.10.636645
MA0052.10.945011
MA0055.10.0406078
MA0056.10
MA0057.10.117936
MA0058.10.384683
MA0059.10.397033
MA0060.10.232592
MA0061.10.261749
MA0063.10
MA0066.10.616444
MA0067.11.27078
MA0068.10.121435
MA0069.10.945354
MA0070.10.93557
MA0071.10.519509
MA0072.10.927016
MA0073.10.00782298
MA0074.10.580087
MA0076.10.356883
MA0077.10.905143
MA0078.10.670113
MA0081.10.420276
MA0083.11.02098
MA0084.11.59945
MA0087.10.977537
MA0088.10.0841779
MA0089.10
MA0090.10.446539
MA0091.10.494398
MA0092.10.446857
MA0093.10.329976
MA0095.10
MA0098.10
MA0100.10.568369
MA0101.10.406019
MA0103.10.920496
MA0105.10.162418
MA0106.10.677988
MA0107.10.342432
MA0108.20.763162
MA0109.10
MA0111.11.16549
MA0113.10.649407
MA0114.10.719313
MA0115.11.0246
MA0116.11.51389
MA0117.10.992087
MA0119.11.84721
MA0122.11.01209
MA0124.11.21735
MA0125.11.14291
MA0130.10
MA0131.10.735438
MA0132.10
MA0133.10
MA0135.11.05845
MA0136.10.600242
MA0139.10.202522
MA0140.10.568252
MA0141.10.964041
MA0142.10.814115
MA0143.10.665982
MA0144.10.72625
MA0145.10.304732
MA0146.10.0256827
MA0147.10.274511
MA0148.10.49752
MA0149.10.411562
MA0062.20.167299
MA0035.20.573016
MA0039.20.014361
MA0138.20.727395
MA0002.20.205289
MA0137.20.365364
MA0104.20.218974
MA0047.20.626803
MA0112.20.0910939
MA0065.20.0914071
MA0150.10.465855
MA0151.10
MA0152.10.626912
MA0153.11.07519
MA0154.10.126143
MA0155.10.336768
MA0156.10.356017
MA0157.10.781683
MA0158.10
MA0159.10.776527
MA0160.10.50056
MA0161.10
MA0162.10.0312493
MA0163.10.116706
MA0164.10.600609
MA0080.20.343316
MA0018.20.610433
MA0099.20.721008
MA0079.20.0190804
MA0102.21.65195
MA0258.10.246285
MA0259.10.26402
MA0442.10
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