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MCL coexpression mm9:92: Difference between revisions

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{{MCL_coexpression_mm9
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(D200-domain) cytokine receptor binding;1.86034201046507e-05;16156,16191,16163,16198!GO:0005125;cytokine activity;1.86034201046507e-05;16156,16191,16163,16198,14176,56708!GO:0008083;growth factor activity;0.00250463816784521;16156,16191,16198,14176!GO:0005102;receptor binding;0.00326751961204418;16156,16191,16163,16198,14176,56708!GO:0005615;extracellular space;0.025157508354791;16163,12836,16156,16191,68567,14176,16198,56708!GO:0005308;creatine transporter activity;0.025157508354791;102857!GO:0005144;interleukin-13 receptor binding;0.025157508354791;16163!GO:0005140;interleukin-9 receptor binding;0.025157508354791;16198!GO:0005309;creatine:sodium symporter activity;0.025157508354791;102857!GO:0005142;interleukin-11 receptor binding;0.025157508354791;16156!GO:0042225;interleukin-5 biosynthetic process;0.025157508354791;16198!GO:0017047;adrenocorticotropin-releasing hormone binding;0.025157508354791;12919!GO:0045405;regulation of interleukin-5 biosynthetic process;0.025157508354791;16198!GO:0015881;creatine transport;0.025157508354791;102857!GO:0045407;positive regulation of interleukin-5 biosynthetic process;0.025157508354791;16198!GO:0044421;extracellular region part;0.0305231013189292;16163,12836,16156,16191,68567,14176,16198,56708!GO:0005137;interleukin-5 receptor binding;0.0377155873938278;16191!GO:0017046;peptide hormone binding;0.0377155873938278;12919!GO:0032634;interleukin-5 production;0.0377155873938278;16198!GO:0004692;cGMP-dependent protein kinase activity;0.0377155873938278;19092!GO:0051247;positive regulation of protein metabolic 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|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.778001303149599,0.482935312308361,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
|gostat_on_MCL_coexpression=GO:0005126;hematopoietin/interferon-class (D200-domain) cytokine receptor binding;1.86034201046507e-05;16156,16191,16163,16198!GO:0005125;cytokine activity;1.86034201046507e-05;16156,16191,16163,16198,14176,56708!GO:0008083;growth factor activity;0.00250463816784521;16156,16191,16198,14176!GO:0005102;receptor binding;0.00326751961204418;16156,16191,16163,16198,14176,56708!GO:0005615;extracellular space;0.025157508354791;16163,12836,16156,16191,68567,14176,16198,56708!GO:0005308;creatine transporter activity;0.025157508354791;102857!GO:0005144;interleukin-13 receptor binding;0.025157508354791;16163!GO:0005140;interleukin-9 receptor binding;0.025157508354791;16198!GO:0005309;creatine:sodium symporter activity;0.025157508354791;102857!GO:0005142;interleukin-11 receptor binding;0.025157508354791;16156!GO:0042225;interleukin-5 biosynthetic process;0.025157508354791;16198!GO:0017047;adrenocorticotropin-releasing hormone binding;0.025157508354791;12919!GO:0045405;regulation of interleukin-5 biosynthetic process;0.025157508354791;16198!GO:0015881;creatine transport;0.025157508354791;102857!GO:0045407;positive regulation of interleukin-5 biosynthetic process;0.025157508354791;16198!GO:0044421;extracellular region part;0.0305231013189292;16163,12836,16156,16191,68567,14176,16198,56708!GO:0005137;interleukin-5 receptor binding;0.0377155873938278;16191!GO:0017046;peptide hormone binding;0.0377155873938278;12919!GO:0032634;interleukin-5 production;0.0377155873938278;16198!GO:0004692;cGMP-dependent protein kinase activity;0.0377155873938278;19092!GO:0051247;positive regulation of protein metabolic process;0.04664591983252;16191,16198!
|ontology_enrichment_celltype=CL:0000217!1.87e-86!2;CL:0000328!1.87e-86!2;CL:0002573!1.87e-86!2;CL:0002376!1.87e-86!2;CL:0000218!1.87e-86!2;CL:0000692!1.87e-86!2;CL:0002377!1.87e-86!2;CL:0002375!1.87e-86!2;CL:0000215!3.28e-58!3;CL:0000630!3.28e-58!3;CL:0000325!6.66e-30!6;CL:0000333!1.57e-18!10;CL:0000095!1.57e-18!10;CL:0000243!1.57e-18!10;CL:0000123!1.57e-18!10;CL:0000125!1.57e-18!10;CL:0000030!1.57e-18!10;CL:0000339!1.57e-18!10
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000010!5.67e-17!11
}}

Latest revision as of 14:40, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:109320794..109320838,-p@chr10:109320794..109320838
-
Mm9::chr10:119799722..119799725,-p@chr10:119799722..119799725
-
Mm9::chr10:119807254..119807257,-p@chr10:119807254..119807257
-
Mm9::chr10:17797302..17797310,+p@chr10:17797302..17797310
+
Mm9::chr10:17797357..17797381,+p@chr10:17797357..17797381
+
Mm9::chr10:85649293..85649317,-p@chr10:85649293..85649317
-
Mm9::chr10:88896799..88896836,-p@chr10:88896799..88896836
-
Mm9::chr10:89083964..89083982,-p1@Slc17a8
Mm9::chr11:19939078..19939081,+p@chr11:19939078..19939081
+
Mm9::chr11:35657903..35657922,-p@chr11:35657903..35657922
-
Mm9::chr11:53448200..53448205,-p1@Il13
Mm9::chr11:53534292..53534297,+p1@Il5
Mm9::chr11:70004825..70004828,-p@chr11:70004825..70004828
-
Mm9::chr11:70012374..70012379,+p@chr11:70012374..70012379
+
Mm9::chr11:8345098..8345105,-p@chr11:8345098..8345105
-
Mm9::chr11:95431141..95431161,+p@chr11:95431141..95431161
+
Mm9::chr11:99720036..99720055,-p@chr11:99720036..99720055
-
Mm9::chr11:99720058..99720068,-p@chr11:99720058..99720068
-
Mm9::chr12:109726417..109726425,+p@chr12:109726417..109726425
+
Mm9::chr12:109726441..109726451,+p@chr12:109726441..109726451
+
Mm9::chr12:45626544..45626549,+p@chr12:45626544..45626549
+
Mm9::chr12:45626593..45626609,+p@chr12:45626593..45626609
+
Mm9::chr12:45626625..45626647,+p@chr12:45626625..45626647
+
Mm9::chr12:45626679..45626689,+p@chr12:45626679..45626689
+
Mm9::chr12:45626698..45626717,+p@chr12:45626698..45626717
+
Mm9::chr12:45626725..45626728,+p@chr12:45626725..45626728
+
Mm9::chr12:77883259..77883263,+p@chr12:77883259..77883263
+
Mm9::chr13:13485661..13485690,-p3@Gpr137b
Mm9::chr13:20332675..20332683,+p@chr13:20332675..20332683
+
Mm9::chr13:56583616..56583619,-p1@Il9
Mm9::chr13:5863061..5863072,+p@chr13:5863061..5863072
+
Mm9::chr13:96214718..96214732,-p1@Crhbp
Mm9::chr14:32478998..32479009,+p@chr14:32478998..32479009
+
Mm9::chr14:32542200..32542203,-p@chr14:32542200..32542203
-
Mm9::chr15:7447375..7447379,+p@chr15:7447375..7447379
+
Mm9::chr15:7447493..7447500,+p@chr15:7447493..7447500
+
Mm9::chr15:76032691..76032704,-p@chr15:76032691..76032704
-
Mm9::chr15:80502052..80502063,+p4@Fam83f
Mm9::chr15:80502078..80502107,+p2@Fam83f
Mm9::chr15:80502116..80502126,+p5@Fam83f
Mm9::chr15:87455644..87455660,+p7@Fam19a5
Mm9::chr15:87455675..87455691,+p1@Fam19a5
Mm9::chr15:87482469..87482479,+p@chr15:87482469..87482479
+
Mm9::chr15:87485366..87485375,+p@chr15:87485366..87485375
+
Mm9::chr16:42750876..42750877,+p@chr16:42750876..42750877
+
Mm9::chr17:10914421..10914424,-p@chr17:10914421..10914424
-
Mm9::chr17:11578268..11578275,-p@chr17:11578268..11578275
-
Mm9::chr17:23813529..23813550,-p@chr17:23813529..23813550
-
Mm9::chr17:27698251..27698260,+p@chr17:27698251..27698260
+
Mm9::chr17:27698285..27698292,+p@chr17:27698285..27698292
+
Mm9::chr17:27698297..27698304,+p@chr17:27698297..27698304
+
Mm9::chr17:27698308..27698322,+p@chr17:27698308..27698322
+
Mm9::chr18:24270578..24270588,-p@chr18:24270578..24270588
-
Mm9::chr18:24270590..24270609,-p@chr18:24270590..24270609
-
Mm9::chr18:5404428..5404435,-p@chr18:5404428..5404435
-
Mm9::chr18:5404496..5404500,-p@chr18:5404496..5404500
-
Mm9::chr18:5404573..5404587,-p@chr18:5404573..5404587
-
Mm9::chr18:57302272..57302282,+p16@Megf10
Mm9::chr18:57302324..57302348,+p6@Megf10
Mm9::chr18:57302359..57302364,+p18@Megf10
Mm9::chr18:57302368..57302389,+p7@Megf10
Mm9::chr18:57302392..57302409,+p11@Megf10
Mm9::chr18:57302410..57302419,+p17@Megf10
Mm9::chr18:60878337..60878341,-p@chr18:60878337..60878341
-
Mm9::chr18:60878342..60878360,-p@chr18:60878342..60878360
-
Mm9::chr18:60878370..60878380,-p@chr18:60878370..60878380
-
Mm9::chr19:4214416..4214432,+p1@Clcf1
Mm9::chr19:5447770..5447773,-p@chr19:5447770..5447773
-
Mm9::chr19:59116443..59116460,-p@chr19:59116443..59116460
-
Mm9::chr1:178765650..178765663,+p@chr1:178765650..178765663
+
Mm9::chr1:185424641..185424650,+p@chr1:185424641..185424650
+
Mm9::chr1:58782860..58782907,+p@chr1:58782860..58782907
+
Mm9::chr1:74428217..74428226,+p12@Slc11a1
Mm9::chr2:112219423..112219441,+p2@2410042D21Rik
Mm9::chr2:13480132..13480139,-p@chr2:13480132..13480139
-
Mm9::chr2:13496978..13496987,+p@chr2:13496978..13496987
+
Mm9::chr2:13497144..13497155,+p@chr2:13497144..13497155
+
Mm9::chr2:13497160..13497184,+p@chr2:13497160..13497184
+
Mm9::chr2:148539476..148539483,+p@chr2:148539476..148539483
+
Mm9::chr3:57305683..57305692,-p@chr3:57305683..57305692
-
Mm9::chr3:79740359..79740368,+p@chr3:79740359..79740368
+
Mm9::chr4:135529408..135529431,-p@chr4:135529408..135529431
-
Mm9::chr4:135529437..135529446,-p@chr4:135529437..135529446
-
Mm9::chr5:139954888..139954902,-p4@Zfand2a
Mm9::chr5:28144366..28144367,-p@chr5:28144366..28144367
-
Mm9::chr5:31247969..31247995,-p3@Cgref1
Mm9::chr5:31248027..31248036,-p4@Cgref1
Mm9::chr5:31248044..31248049,-p5@Cgref1
Mm9::chr5:73237669..73237708,-p@chr5:73237669..73237708
-
Mm9::chr5:98683165..98683177,+p3@Fgf5
Mm9::chr5:98683193..98683209,+p4@Fgf5
Mm9::chr5:99395809..99395818,-p11@Prkg2
Mm9::chr6:137465516..137465540,-p@chr6:137465516..137465540
-
Mm9::chr6:137468262..137468263,-p13@Eps8
Mm9::chr6:137468401..137468421,-p3@Eps8
Mm9::chr6:31038213..31038222,-p1@ENSMUST00000123757
Mm9::chr6:31038349..31038357,-p2@ENSMUST00000123757
Mm9::chr6:31038464..31038481,-p@chr6:31038464..31038481
-
Mm9::chr6:31038542..31038552,-p@chr6:31038542..31038552
-
Mm9::chr6:31629332..31629339,+p@chr6:31629332..31629339
+
Mm9::chr6:72331674..72331699,-p@chr6:72331674..72331699
-
Mm9::chr6:72331748..72331753,-p@chr6:72331748..72331753
-
Mm9::chr7:114808192..114808207,+p@chr7:114808192..114808207
+
Mm9::chr7:114866423..114866442,+p@chr7:114866423..114866442
+
Mm9::chr7:137963621..137963654,+p@chr7:137963621..137963654
+
Mm9::chr7:137963832..137963843,+p@chr7:137963832..137963843
+
Mm9::chr7:138004756..138004766,+p@chr7:138004756..138004766
+
Mm9::chr7:138009200..138009202,+p8@Plekha1
Mm9::chr7:138009473..138009484,+p4@Plekha1
Mm9::chr7:138010877..138010906,-p@chr7:138010877..138010906
-
Mm9::chr7:138011022..138011028,+p@chr7:138011022..138011028
+
Mm9::chr7:138011031..138011037,+p@chr7:138011031..138011037
+
Mm9::chr7:138011048..138011054,+p@chr7:138011048..138011054
+
Mm9::chr7:4729743..4729746,-p1@Il11
Mm9::chr8:113317461..113317484,-p@chr8:113317461..113317484
-
Mm9::chr8:113317507..113317514,-p@chr8:113317507..113317514
-
Mm9::chr8:11798720..11798730,+p@chr8:11798720..11798730
+
Mm9::chr8:124754082..124754117,+p@chr8:124754082..124754117
+
Mm9::chr8:74104415..74104425,+p18@Slc27a1
Mm9::chr8:74104427..74104464,+p9@Slc27a1
Mm9::chr9:108884993..108885013,+p4@Col7a1
Mm9::chr9:108885020..108885041,+p3@Col7a1
Mm9::chr9:108885049..108885071,+p5@Col7a1
Mm9::chr9:108886927..108886944,+p@chr9:108886927..108886944
+
Mm9::chr9:14575585..14575594,-p7@1700012B09Rik
Mm9::chr9:24119263..24119266,-p@chr9:24119263..24119266
-
Mm9::chr9:24146097..24146107,+p1@ENSMUST00000098926
Mm9::chr9:24146160..24146163,+p3@ENSMUST00000098926
Mm9::chr9:24172587..24172594,+p@chr9:24172587..24172594
+
Mm9::chr9:32560436..32560445,+p@chr9:32560436..32560445
+
Mm9::chr9:78482024..78482068,+p@chr9:78482024..78482068
+
Mm9::chrX:149092046..149092052,-p@chrX:149092046..149092052
-
Mm9::chrX:70920785..70920788,+p24@Slc6a8
Mm9::chrX:70920839..70920855,+p5@Slc6a8
Mm9::chrX:70920870..70920877,+p21@Slc6a8
Mm9::chrX:70920879..70920886,+p25@Slc6a8
Mm9::chrX:7623717..7623719,+p@chrX:7623717..7623719
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005126hematopoietin/interferon-class (D200-domain) cytokine receptor binding1.86034201046507e-05
GO:0005125cytokine activity1.86034201046507e-05
GO:0008083growth factor activity0.00250463816784521
GO:0005102receptor binding0.00326751961204418
GO:0005615extracellular space0.025157508354791
GO:0005308creatine transporter activity0.025157508354791
GO:0005144interleukin-13 receptor binding0.025157508354791
GO:0005140interleukin-9 receptor binding0.025157508354791
GO:0005309creatine:sodium symporter activity0.025157508354791
GO:0005142interleukin-11 receptor binding0.025157508354791
GO:0042225interleukin-5 biosynthetic process0.025157508354791
GO:0017047adrenocorticotropin-releasing hormone binding0.025157508354791
GO:0045405regulation of interleukin-5 biosynthetic process0.025157508354791
GO:0015881creatine transport0.025157508354791
GO:0045407positive regulation of interleukin-5 biosynthetic process0.025157508354791
GO:0044421extracellular region part0.0305231013189292
GO:0005137interleukin-5 receptor binding0.0377155873938278
GO:0017046peptide hormone binding0.0377155873938278
GO:0032634interleukin-5 production0.0377155873938278
GO:0004692cGMP-dependent protein kinase activity0.0377155873938278
GO:0051247positive regulation of protein metabolic process0.04664591983252



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
peripheral nervous system5.67e-1711


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.12.31341e-07
MA0004.10.995084
MA0006.10.0432748
MA0007.11.99514
MA0009.10.345557
MA0014.19.61274e-07
MA0017.10.800397
MA0019.10.124035
MA0024.10.117409
MA0025.10.122152
MA0027.11.29451
MA0028.10.00205434
MA0029.10.103073
MA0030.10.785402
MA0031.10.0191726
MA0038.10.366704
MA0040.10.0410756
MA0041.10.067275
MA0042.10.0987079
MA0043.10.235117
MA0046.10.0473472
MA0048.10.139001
MA0050.11.26205
MA0051.10.234146
MA0052.10.672628
MA0055.10.0170448
MA0056.10
MA0057.10.012643
MA0058.10.9733
MA0059.10.67611
MA0060.16.70952e-05
MA0061.10.112021
MA0063.10
MA0066.10.743227
MA0067.11.6167
MA0068.10.242675
MA0069.10.0432623
MA0070.10.15841
MA0071.10.758935
MA0072.10.151652
MA0073.10.510101
MA0074.11.08618
MA0076.10.00525377
MA0077.10.317291
MA0078.11.29588
MA0081.10.145132
MA0083.10.234336
MA0084.10.406076
MA0087.10.193825
MA0088.10.183113
MA0089.10
MA0090.11.50114
MA0091.10.637863
MA0092.10.435077
MA0093.10.917304
MA0095.10
MA0098.10
MA0100.10.376763
MA0101.10.291133
MA0103.10.0490063
MA0105.10.000147828
MA0106.10.310855
MA0107.10.388996
MA0108.20.503092
MA0109.10
MA0111.10.0778898
MA0113.12.28457
MA0114.10.158017
MA0115.10.237881
MA0116.10.259735
MA0117.10.0566054
MA0119.10.195641
MA0122.10.225733
MA0124.10.90045
MA0125.10.367299
MA0130.10
MA0131.10.675108
MA0132.10
MA0133.10
MA0135.10.0793246
MA0136.10.176183
MA0139.10.00138777
MA0140.10.132818
MA0141.11.77285
MA0142.10.386439
MA0143.10.691973
MA0144.10.0733311
MA0145.10.0665063
MA0146.12.77407e-06
MA0147.10.381542
MA0148.10.0266286
MA0149.10.129919
MA0062.20.000536847
MA0035.20.571767
MA0039.23.97676e-06
MA0138.20.113221
MA0002.20.26729
MA0137.20.0161959
MA0104.20.0967728
MA0047.20.0142084
MA0112.20.0476025
MA0065.20.0485001
MA0150.17.32232
MA0151.10
MA0152.10.787422
MA0153.10.085752
MA0154.10.046945
MA0155.10.315601
MA0156.10.0974784
MA0157.10.326752
MA0158.10
MA0159.10.0726718
MA0160.14.01031
MA0161.10
MA0162.10.00500536
MA0163.10.00811688
MA0164.10.303668
MA0080.21.24671
MA0018.20.0400031
MA0099.213.9734
MA0079.20.000291524
MA0102.21.13725
MA0258.10.665669
MA0259.10.0758627
MA0442.10
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