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Coexpression cluster:C1227: Difference between revisions

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{{Coexpression_clusters
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|full_id=C1227_Osteoblast_Smooth_tenocyte_Fibroblast_Chondrocyte_Aortic_Hair
|id=C1227
}}

Latest revision as of 11:40, 17 September 2013


Full id: C1227_Osteoblast_Smooth_tenocyte_Fibroblast_Chondrocyte_Aortic_Hair



Phase1 CAGE Peaks

Hg19::chr17:39969465..39969488,+p3@FKBP10
Hg19::chr17:39974337..39974365,+p@chr17:39974337..39974365
+
Hg19::chr17:39974415..39974450,+p@chr17:39974415..39974450
+
Hg19::chr17:39975455..39975487,+p5@FKBP10
Hg19::chr17:39975580..39975609,+p4@FKBP10
Hg19::chr17:39975867..39975886,+p12@FKBP10
Hg19::chr1:12012673..12012703,+p@chr1:12012673..12012703
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
epithelial vesicle2.47e-1978
dense mesenchyme tissue9.68e-1873
somite2.20e-1771
presomitic mesoderm2.20e-1771
presumptive segmental plate2.20e-1771
dermomyotome2.20e-1771
trunk paraxial mesoderm2.20e-1771
paraxial mesoderm3.61e-1772
presumptive paraxial mesoderm3.61e-1772
mesenchyme7.17e-17160
entire embryonic mesenchyme7.17e-17160
splanchnic layer of lateral plate mesoderm8.42e-1683
vasculature2.28e-1578
vascular system2.28e-1578
trunk mesenchyme2.67e-15122
multilaminar epithelium2.69e-1583
skeletal muscle tissue7.28e-1562
striated muscle tissue7.28e-1562
myotome7.28e-1562
unilaminar epithelium1.22e-14148
muscle tissue2.35e-1464
musculature2.35e-1464
musculature of body2.35e-1464
artery2.81e-1442
arterial blood vessel2.81e-1442
arterial system2.81e-1442
epithelial tube4.67e-14117
epithelial tube open at both ends4.71e-1459
blood vessel4.71e-1459
blood vasculature4.71e-1459
vascular cord4.71e-1459
trunk1.90e-13199
vessel3.95e-1368
organism subdivision7.08e-13264
systemic artery1.56e-1133
systemic arterial system1.56e-1133
cardiovascular system6.23e-11109
circulatory system3.32e-10112
multi-cellular organism1.99e-09656
cell layer9.16e-09309
integument1.35e-0846
integumental system1.35e-0846
epithelium1.64e-08306
multi-tissue structure3.88e-08342
surface structure5.51e-0899
mesoderm4.65e-07315
mesoderm-derived structure4.65e-07315
presumptive mesoderm4.65e-07315
anatomical system6.80e-07624
skin of body7.79e-0741
anatomical group8.39e-07625


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.213534
MA0004.10.502801
MA0006.10.341337
MA0007.10.483857
MA0009.10.973289
MA0014.10.187674
MA0017.10.380797
MA0019.10.652951
MA0024.10.867125
MA0025.11.10816
MA0027.12.59001
MA0028.10.35747
MA0029.10.886702
MA0030.10.875089
MA0031.10.809638
MA0038.10.60704
MA0040.10.892629
MA0041.10.521615
MA0042.10.48922
MA0043.12.23229
MA0046.10.962263
MA0048.10.766755
MA0050.10.490116
MA0051.10.602745
MA0052.10.896548
MA0055.10.158296
MA0056.10
MA0057.10.369442
MA0058.10.406232
MA0059.10.404929
MA0060.10.224688
MA0061.10.575931
MA0063.10
MA0066.11.47685
MA0067.11.29359
MA0068.10.162298
MA0069.10.958358
MA0070.10.947018
MA0071.11.39306
MA0072.10.942461
MA0073.10.488614
MA0074.10.60198
MA0076.11.08222
MA0077.10.934645
MA0078.10.703614
MA0081.10.405093
MA0083.10.980893
MA0084.11.48179
MA0087.10.939982
MA0088.11.37625
MA0089.10
MA0090.11.95014
MA0091.10.505453
MA0092.10.467172
MA0093.10.344385
MA0095.10
MA0098.10
MA0100.10.621149
MA0101.11.64331
MA0103.10.332048
MA0105.13.6909
MA0106.10.648997
MA0107.10.752965
MA0108.20.806528
MA0109.10
MA0111.10.45062
MA0113.10.665691
MA0114.10.269076
MA0115.11.21667
MA0116.10.277571
MA0117.11.01134
MA0119.10.388712
MA0122.11.03753
MA0124.11.17486
MA0125.11.0901
MA0130.10
MA0131.10.722072
MA0132.10
MA0133.10
MA0135.11.00402
MA0136.10.614215
MA0139.10.547495
MA0140.10.564957
MA0141.10.403171
MA0142.10.777365
MA0143.10.66587
MA0144.11.30855
MA0145.10.276317
MA0146.10.547931
MA0147.10.281049
MA0148.10.528066
MA0149.10.555119
MA0062.20.193221
MA0035.20.564239
MA0039.20.243958
MA0138.20.704862
MA0002.20.213296
MA0137.20.36398
MA0104.20.223944
MA0047.20.636643
MA0112.20.262665
MA0065.20.0828768
MA0150.10.430951
MA0151.10
MA0152.10.571637
MA0153.11.07307
MA0154.11.13451
MA0155.10.534073
MA0156.10.36627
MA0157.10.749547
MA0158.10
MA0159.10.281681
MA0160.10.543522
MA0161.10
MA0162.10.106355
MA0163.11.30651
MA0164.10.678332
MA0080.20.344472
MA0018.20.650405
MA0099.20.572
MA0079.21.1389
MA0102.21.51913
MA0258.11.27333
MA0259.10.289405
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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