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{{Coexpression_clusters
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ligase activity!0.00362062875309078!23205$GO:0001676!long-chain fatty acid metabolic process!0.00723933921700654!23205$GO:0000038!very-long-chain fatty acid metabolic process!0.00723933921700654!23205$GO:0004467!long-chain-fatty-acid-CoA ligase activity!0.00723933921700654!23205$GO:0015645!fatty-acid ligase activity!0.00723933921700654!23205$GO:0042552!myelination!0.0128616026527903!23205$GO:0016877!ligase activity, forming carbon-sulfur bonds!0.0128616026527903!23205$GO:0008366!axon ensheathment!0.0128616026527903!23205$GO:0007272!ensheathment of neurons!0.0128616026527903!23205$GO:0001508!regulation of action 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|full_id=C1213_thymus_Dendritic_CD4_non_chronic_vein_CD133
|gostat_on_coexpression_clusters=GO:0031957!very-long-chain-fatty-acid-CoA ligase activity!0.00362062875309078!23205$GO:0001676!long-chain fatty acid metabolic process!0.00723933921700654!23205$GO:0000038!very-long-chain fatty acid metabolic process!0.00723933921700654!23205$GO:0004467!long-chain-fatty-acid-CoA ligase activity!0.00723933921700654!23205$GO:0015645!fatty-acid ligase activity!0.00723933921700654!23205$GO:0042552!myelination!0.0128616026527903!23205$GO:0016877!ligase activity, forming carbon-sulfur bonds!0.0128616026527903!23205$GO:0008366!axon ensheathment!0.0128616026527903!23205$GO:0007272!ensheathment of neurons!0.0128616026527903!23205$GO:0001508!regulation of action potential!0.0144658947339719!23205
|id=C1213
|ontology_enrichment_celltype=CL:0000037!5.39e-29!172;CL:0000566!5.39e-29!172;CL:0000738!9.56e-29!140;CL:0000988!1.47e-26!182;CL:0002032!6.25e-25!165;CL:0000837!6.25e-25!165;CL:0002087!3.28e-22!119;CL:0000542!1.50e-20!53;CL:0000051!1.50e-20!53;CL:0000838!2.09e-20!52;CL:0002031!4.23e-20!124;CL:0000791!2.87e-13!18;CL:0000789!2.87e-13!18;CL:0002420!2.87e-13!18;CL:0002419!2.87e-13!18;CL:0000790!2.87e-13!18;CL:0000084!3.10e-13!25;CL:0000827!3.10e-13!25;CL:0000625!1.01e-08!11;CL:0000763!2.78e-08!112;CL:0000049!2.78e-08!112;CL:0002057!2.42e-07!42;CL:0000945!4.28e-07!24;CL:0000826!4.28e-07!24
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!4.13e-15!115;UBERON:0002390!6.84e-12!102;UBERON:0003061!6.84e-12!102;UBERON:0002193!5.58e-11!112;UBERON:0000178!9.07e-09!15;UBERON:0000179!9.07e-09!15;UBERON:0000463!9.07e-09!15
|tfbs_overrepresentation=0.31043,0.131575,0.564335,0.107813,0.405466,0.547045,0.0974871,0.713283,0.0746874,0.0589549,0.295561,0.448908,0.386236,0.269614,0.313114,0.138515,0.298536,0.214302,0.119001,0.234193,0.385995,0.282418,0.0174538,0.20757,0.0943256,0.432377,0.422025,0.199011,0.303793,0.0224893,0.414424,0.246136,0.0415685,0.104091,0.148393,0.186108,0.934067,0.097401,0.258596,0.148774,0.210798,0.0564873,0.296737,0.377815,0.259708,0.0825288,0.0864669,0.373342,0.240639,0.260266,0.323223,0.12188,0.156121,0.00166139,0.0954432,0.0873518,0.232986,0.427667,0.173296,0.229205,0.0673274,0.0556516,0.235283,0.168316,0.122724,0.113864,0.637,0.134457,0.189423,0.34721,0.670888,0.150845,0.195543,0.25669,0.0173573,0.0394864,0.210826,0.0989984,0.0847661,0.0168408,0.209062,0.451469,0.0963703,0.247724,0.552245,0.491847,0.143736,0.421411,0.643105,0.140328,0.18877,0.111901,0.208559,0.107066,0.188008,0.248084,0.871457,0.322402,0.203166,0.526481,0.129026,0.529658,0.300234,0.0843602,0.0209057,0.0929061,0.149379,0.618184,0.304684,0.519136,0.375285,0.0775356,0.314757,0.0407805,0.220427,0.0769904,0.0468147,0.127234,0.294794,0.184794,0.346582,0.431052,0.296899,0.188824,0.222747,0.365096,0.198942,0.034178,0.185876,0.286955,0.133529,0.165976,0.128445,0.0523619,0.269253,0.234279,0.144853,0.124383,0.0754012,0.00920461,0.052339,0.272785,0.412653,0.326814,0.625002,0.154324,0.215565,0.1856,0.0885156,0.259543,0.406997,0.30366,0.371915,0.0609284,0.0968299,0.253074,0.165818,0.453904,0.116496,0.0769293,0.452804,0.208356,0.251281,0.311437,0.525489,0.246608,0.0909267,0.272323,0.0916381,0.582261,0.370083,0.292316,0.426997,0.121785,0.17666,0.197691,0.297301,0.373889,0.367859,0.0811784,0.332099,0.262763,0.0627829,0.249166,0.16364,0.255634,0.376054,0.0912436,0.18278,0.35905,0.232364,0.38363,0.263667,0.45461,0.243403,0.106408,0.173147,0.135052,0.0119867,0.237426,0.196091,0.135293,0.0704675,0.135734,0.289872,0.503773,0.525644,0.319069,0.416735,0.367697,0.103767,0.226759,0.260173,0.243859,0.58295,0.350868,0.341984,0.219863,0.140859,0.224003,0.300341,0.662833,0.32693,0.336135,0.163924,0.270849,0.294471,0.189218,0.135411,0.134214,0.585202,0.678094,0.0949171,0.169481,0.209657,0.204086,0.106746,0.509502,0.340697,0.110275,0.375058,0.63269,0.214704,0.183242,0.25057,0.290614,0.179951,0.241366,0.0972768,0.252043,0.0626794,0.37985,0.380877,0.213951,0.214075,0.333636,0.232558,0.409093,0.154888,0.604062,0.138561,0.361831,0.340466,0.273737,0.0786852,0.179028,0.179229,0.201771,0.254117,0.16741,0.532883,0.141494,0.496492,0.748734,0.190495,0.0865316,0.27777,0.871477,0.0755362,0.971688,0.682134,0.13079,0.380957,0.737802,0.247108,0.673015,0.507115,0.161526,0.664373,0.5782,0.467833,0.608158,0.691446,0.606605,0.532767,0.385776,0.523169,0.553463,0.342602,0.693154,0.86915,0.165452,0.38355,0.283193,0.373708,0.368598,0.238054,0.241288,0.437154,0.727324,0.668415,0.179104,0.439013,0.101341,0.0956435,0.660738,0.71452,0.457495,0.494595,0.530579,0.205002,0.199689,0.589017,0.445808,0.225057,0.884305,0.54096,0.22091,0.326362,0.552809,0.750148,0.0531627,0.133385,0.554465,0.193985,0.741035,0.664607,0.596959,0.0714868,0.374876,0.778743,0.76438,0.222014,0.528337,0.467165,0.380732,0.261292,0.832986,0.521679,0.402498,0.804395,0.814166,0.513784,0.144423,0.537738,0.775056,0.340223,0.14951,0.162309,0.379192,0.62513,0.248034,0.603224,0.711307,0.263267,0.116352,0.846076,0.40355,0.437649,0.583275,0.523849,0.102102,0.165804,0.454926,0.702452,0.344036,0.483874,0.557198,0.257351,0.44677,0.549109,0.603229,0.501963,0.532418,0.340787,0.144312,0.453428,0.61578,0.401761,0.327395,0.858503,0.364981,0.0704814,0.13684,0.505343,0.480554,0.246698,0.305806,0.307188,0.314229,0.667503,0.402503,0.762469,0.148267,0.320625,0.10531,0.291113,0.155864,0.286678,0.215083,0.2811,0.195286,0.542255,0.625729,0.574375,0.0551228,0.362878,0.224884,0.822125,0.184595,0.508647,0.646316,0.450384,0.123826,0.133613,0.284394,0.767511,0.837502,0.416603,0.824299,0.914545,0.387693,0.518983,0.252097,0.846682,0.180871,0.300014,0.414327,0.820036,0.33353,0.470604,0.296042,0.460268,0.387548,0.195754,0.133496,0.823955,0.666956,0.630454,0.836153,0.265981,0.443447,0.122637,0.427426,0.901882,0.588029,0.15528,0.125135,0.392877,0.172615,0.129203,0.304883,0.445623,0.412193,0.744608,0.394333,0.39153,0.241931,0.54931,0.0986558,0.569749,0.270589,0.2868,0.231853,0.525257,0.140425,0.673929,0.0412928,0.570618,0.535059,0.00663213,0.105116,0.351863,0.247203,0.227166,0.197433,0.190714,0.0632636,0.232295,0.0993709,0.00905448,0.264955,0.275796,0.42369,0.394858,0.62923,0.112748,0.182834,0.148755,0.374546,0.240628,0.438923,0.61103,0.398206,0.28169,0.3861,0.108827,0.405826,0.703418,0.273081,0.363066,0.378645,0.35119,0.192669,0.208253,0.0260665,0.444023,0.232159,0.528175,0.0111948,0.359315,0.298797,0.425775,0.0687597,0.280435,0.10082,0.117938,0.421126,0.321571,0.176362,0.212715,0.334514,0.264825,0.19886,0.125399,0.182257,0.243178,0.291561,0.0337354,0.146629,0.107376,0.440859,0.177111,0.167984,0.337564,0.394053,0.123448,0.17256,0.126216,0.0947479,0.0787488,0.0883646,0.0324422,0.353144,0.407665,0.00633039,0.0750505,0.660283,0.0754745,0.632378,0.114847,0.0896836,0.133679,0.718626,0.038021,0.235824,0.23812,0.506939,0.0654706,0.844302,0.305348,0.0883079,0.192275,0.123717,0.3044,0.0320798,0.435034,0.388488,0.27954,0.326131,0.468189,0.545823,0.168686,0.35711,0.180717,0.375467,0.614081,0.311267,0.299453,0.347601,0.000491774,0.195385,0.578705,0.187498,0.106912,0.207535,0.747423,0.00479238,0.17144,0.236468,0.274647,0.280244,0.139014,0.750867,0.1168,0.216736,0.112879,0.138362,0.1674,0.205022,0.304414,0.0775871,0.1646,0.175877,0.607567,0.916686,0.435374,0.54926,0.25636,0.392755,0.366993,0.843094,0.12921,0.107541,0.688004,0.136306,0.362226,0.565792,0.158567,0.119065,0.192217,0.0810658,0.268889,0.0751905,0.92061,0.619849,0.00230278,0.436925,0.234633,0.150144,0.235575,0.111506,0.209512,0.415762,0.167545,0.1033,0.238509,0.156356,0.450242,0.0585622,0.0857464,0.282499,0.101873,0.121306,0.246526,0.203595,0.356991,0.227948,0.0216279,0.128341,0.129502,0.168391,0.545636,0.320047,0.397073,0.437057,0.221207,0.603174,0.358,0.621995,0.318595,0.140173,0.390753,0.312917,0.805801,0.326484,0.15977,0.201434,0.134947,0.304849,0.316782,0.212636,0.325012,0.071344,0.0908811,0.291345,0.453507,0.491263,0.188656,0.255995,0.184894,0.242,0.0326333,0.243363,0.382464,0.361244,0.207462,0.51104,0.487422,0.29768,0.217499,0.154075,0.225368,0.244195,0.0586175,0.348776,0.198885,0.608664,0.0687278,0.0865271,0.1797,0.379465,0.327304,0.581915,0.498434,0.132491,0.48467,0.0778828,0.436987,0.458334,0.12497,0.659137,0.0821811,0.35171,0.279549,0.0984834,0.284421,0.71736,0.658832,0.405011,0.344864,0.458949,0.114603,0.741039,0.659829,0.14201,0.0138567,0.401507,0.692805,0.281389,0.123881,0.673541,0.86822,0.223036,0.380231,0.35015,0.00662952,0.0216683,0.0816012,0.744931,0.822139,0.863887,0.855857,0.451787,0.244289,0.656157,0.315577,0.184591,0.805952,0.558605,0.363477,0.54891,0.341975,0.0594545,0.0463064,0.141895,0.780774,0.615729,0.433619,0.501908,0.401378,0.478352,0.969954,0.32181,0.598275,0.134463,0.337191,0.629545,0.224391,0.0786619,0.976385,0.664234,0.972335,0.779967,0.692633,0.829635,0.45244,0.411785,0.0969806,0.101625,0.565657,0.152945,0.0426121,0.0807208,0.0278466,0.327011,0.299176,0.710278,0.210121,0.220526,0.0844703,0.341296,0.0242779,0.258349,0.184142,0.0464251,0.220515,0.373172,0.181869,0.867555,0.386822,0.706206,0.029342,0.0640951,0.240432,0.619962,0.88908,0.681127,0.514569,0.977195,0.268974,0.0217399,0.715629,0.357569,0.0594669,0.597705,0.32901,0.100922,0.7547,0.294507,0.484505,0.346938,0.40211,0.183851,0.588416,0.198404,0.362009,0.611179,0.664218,0.516101,0.706724,0.654039,0.832266,0.685486,0.283731,0.466416,0.411899,0.525367,0.667,0.748565,0.635414,0.528332,0.421737,0.0551791,0.474724,0.294861,0.574524,0.570287,0.474491,0.68023,0.808962,0.490466,0.676249,0.760368,0.487711,0.440345,0.0873023,0.400622,0.391073,0.766374,0.632822,0.575489,0.175413,0.540565,0.576036,0.775603,0.333846,0.525188,0.657348,0.52794,0.67786,0.0193704,0.646027,0.620377,0.0154932,0.177953,0.31638,0.610982,0.523153,0.564763,0.032608,0.101471,0.364157,0.172412,0.53064,0.415017,0.0769041,0.387804,0.155446,0.385339,0.159832,0.162096,0.338978,0.390233,0.339879,0.438999,0.41967,0.197678,0.0234326,0.34551,0.0315271,0.670197,0.497662,0.103429,0.0518311,0.369586,0.394729,0.116157,0.0220103,0.255224,0.580249,0.436618,0.403472,0.382758,0.264429,0.404954,0.0744027,0.204325,0.265849,0.370442,0.451398,0.177748,0.188364,0.279598,0.420279,0.143312,0.443868,0.150111,0.420451,0.514853,0.244241,0.307495,0.455626,0.0086299,0.124108,0.350305,0.0875262,0.147486,0.117583,0.103076,0.518238,0.40865,0.634608,0.324846,0.25829,0.215261,0.235004,0.133496,0.433115,0.331422,0.440492,0.397558,0.266168,0.504119,0.57634,0.371725,0.334024,0.153743,0.316975,0.435107,0.26559,0.378345,0.380153,0.160696,0.155054,0.507413,0.412407,0.0194676,0.418893,0.300222,0.0903341,0.487504,0.0342258,0.447581,0.482721,0.35808,0.406625,0.296254,0.400859,0.473667,0.327684,0.279523,0.499937,0.444635,0.356463,0.364875,0.211724,0.409573,0.579867,0.536787,0.436872,0.181464,0.40945,0.231548,0.120636,0.121001,0.317719,0.172653,0.0924531,0.120918,0.593272,0.507382,0.425328,0.384398,0.462521,0.0873107,0.179489,0.214126,0.143317,0.261663,0.14273,0.227254,0.147968,0.168955,0.274981,0.236422,0.0999117,0.149301,0.196723,0.0836477,0.287028,0.413461,0.050072,0.545381,0.630108,0.299959,0.509613,0.498355,0.406059,0.452427,0.56256,0.494497,0.366448,0.540845,0.511559,0.280842,0.335456,0.102233,0.404559,0.0458463,0.467154,0.065788,0.249647,0.113392,0.446356,0.248584,0.397145,0.390152,0.18122,0.540199,0.488863,0.342785,0.447064,0.20487,0.603936,0.449548,0.103672,0.209566,0.189123,0.0610821,0.355645,0.0625263,0.169259,0.158122,0.168501,0.220023,0.444217,0.363335,0.0613546,0.432735,0.148874,0.416144,0.648861
}}

Latest revision as of 11:40, 17 September 2013


Full id: C1213_thymus_Dendritic_CD4_non_chronic_vein_CD133



Phase1 CAGE Peaks

Hg19::chr15:78466862..78466878,-p4@ACSBG1
Hg19::chr17:37322317..37322337,-p2@ARL5C
Hg19::chr18:13218882..13218893,+p8@C18orf1
Hg19::chr19:4302375..4302406,-p1@TMIGD2
Hg19::chr3:35683620..35683628,+p49@ARPP21
Hg19::chr6:138189241..138189298,-p1@uc003qhq.1
Hg19::chr6:138189307..138189329,-p3@uc003qhq.1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0031957very-long-chain-fatty-acid-CoA ligase activity0.00362062875309078
GO:0001676long-chain fatty acid metabolic process0.00723933921700654
GO:0000038very-long-chain fatty acid metabolic process0.00723933921700654
GO:0004467long-chain-fatty-acid-CoA ligase activity0.00723933921700654
GO:0015645fatty-acid ligase activity0.00723933921700654
GO:0042552myelination0.0128616026527903
GO:0016877ligase activity, forming carbon-sulfur bonds0.0128616026527903
GO:0008366axon ensheathment0.0128616026527903
GO:0007272ensheathment of neurons0.0128616026527903
GO:0001508regulation of action potential0.0144658947339719



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
adult organism8.81e-08114
thymus1.69e-074
hemolymphoid system gland1.69e-074
thymic region1.69e-074
pharyngeal gland1.69e-074
thymus primordium1.69e-074
hemopoietic organ4.53e-077
immune organ4.53e-077


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.213534
MA0004.10.502801
MA0006.10.341337
MA0007.10.483857
MA0009.10.973289
MA0014.10.187674
MA0017.10.380797
MA0019.11.57204
MA0024.10.867125
MA0025.11.10816
MA0027.12.59001
MA0028.10.35747
MA0029.10.886702
MA0030.10.875089
MA0031.10.809638
MA0038.10.60704
MA0040.10.892629
MA0041.10.521615
MA0042.10.48922
MA0043.10.973609
MA0046.10.962263
MA0048.10.382278
MA0050.10.490116
MA0051.10.602745
MA0052.10.896548
MA0055.10.649431
MA0056.10
MA0057.10.369442
MA0058.10.406232
MA0059.10.404929
MA0060.10.638423
MA0061.10.198335
MA0063.10
MA0066.13.66767
MA0067.11.29359
MA0068.10.488375
MA0069.10.958358
MA0070.10.947018
MA0071.10.567661
MA0072.10.942461
MA0073.10.0282921
MA0074.10.60198
MA0076.11.08222
MA0077.12.1528
MA0078.10.703614
MA0081.10.405093
MA0083.10.980893
MA0084.11.48179
MA0087.12.1637
MA0088.10.0723293
MA0089.10
MA0090.10.436918
MA0091.10.505453
MA0092.10.467172
MA0093.10.344385
MA0095.10
MA0098.10
MA0100.10.621149
MA0101.10.347695
MA0103.10.88373
MA0105.10.340955
MA0106.10.648997
MA0107.10.274127
MA0108.20.806528
MA0109.10
MA0111.10.45062
MA0113.10.665691
MA0114.10.269076
MA0115.11.21667
MA0116.10.277571
MA0117.11.01134
MA0119.10.388712
MA0122.11.03753
MA0124.11.17486
MA0125.11.0901
MA0130.10
MA0131.10.722072
MA0132.10
MA0133.10
MA0135.11.00402
MA0136.10.614215
MA0139.10.547495
MA0140.10.564957
MA0141.10.403171
MA0142.10.777365
MA0143.11.59899
MA0144.10.254954
MA0145.10.980834
MA0146.10.324987
MA0147.10.281049
MA0148.10.528066
MA0149.10.555119
MA0062.21.07166
MA0035.20.564239
MA0039.20.0553061
MA0138.20.704862
MA0002.20.611548
MA0137.20.36398
MA0104.20.223944
MA0047.20.636643
MA0112.21.41281
MA0065.20.591589
MA0150.10.430951
MA0151.10
MA0152.10.571637
MA0153.11.07307
MA0154.10.335384
MA0155.11.36741
MA0156.10.959643
MA0157.10.749547
MA0158.10
MA0159.10.281681
MA0160.10.543522
MA0161.10
MA0162.10.0249953
MA0163.10.632664
MA0164.10.678332
MA0080.21.63199
MA0018.20.650405
MA0099.20.572
MA0079.20.361922
MA0102.21.51913
MA0258.11.27333
MA0259.10.289405
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
WRNIP1#56897231.37713267125030.001688163372057270.0105492786701544



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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