MCL coexpression mm9:307

Phase1 CAGE Peaks

	Short description
Mm9::chr10:127303554..127303563,+	p4@BC089597
Mm9::chr10:39744983..39745000,-	p4@AI317395
Mm9::chr10:39745012..39745024,-	p3@AI317395
Mm9::chr11:113570266..113570286,-	p2@Cpsf4l
Mm9::chr13:17786563..17786620,-	p1@5033411D12Rik
Mm9::chr13:23931270..23931311,+	p2@Slc17a3
Mm9::chr13:34129460..34129474,+	p2@Bphl
Mm9::chr13:47138485..47138555,-	p1@Tpmt
Mm9::chr14:56194642..56194689,+	p@chr14:56194642..56194689 +
Mm9::chr14:56194692..56194703,+	p@chr14:56194692..56194703 +
Mm9::chr14:65059685..65059700,-	p2@Msra
Mm9::chr15:9265320..9265378,+	p1@Ugt3a2
Mm9::chr16:37580223..37580237,+	p4@Hgd
Mm9::chr19:12770273..12770299,+	p1@Keg1
Mm9::chr1:13650535..13650550,-	p2@Lactb2
Mm9::chr1:13650557..13650635,-	p1@Lactb2
Mm9::chr1:9538195..9538206,+	p2@Adhfe1
Mm9::chr4:96330803..96330853,-	p1@Cyp2j5
Mm9::chr6:3938967..3938987,-	p@chr6:3938967..3938987 -
Mm9::chr7:126669716..126669732,+	p3@Acsm5
Mm9::chr8:129965075..129965087,-	p@chr8:129965075..129965087 -
Mm9::chr8:129965091..129965127,-	p@chr8:129965091..129965127 -
Mm9::chr8:23804533..23804553,-	p2@Ikbkb
Mm9::chr9:119266661..119266682,+	p2@Xylb
Mm9::chr9:65478877..65478895,+	p@chr9:65478877..65478895 +
Mm9::chr9:78194969..78194997,-	p2@Gsta2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016491	oxidoreductase activity	0.0316660275023284
GO:0016740	transferase activity	0.0316660275023284
GO:0050093	methanol dehydrogenase activity	0.0316660275023284
GO:0004411	homogentisate 1,2-dioxygenase activity	0.0316660275023284
GO:0008119	thiopurine S-methyltransferase activity	0.0316660275023284
GO:0004856	xylulokinase activity	0.0316660275023284
GO:0008113	peptide-methionine-(S)-S-oxide reductase activity	0.0474574142287016
GO:0005506	iron ion binding	0.0474574142287016
GO:0047961	glycine N-acyltransferase activity	0.0474574142287016
GO:0007252	I-kappaB phosphorylation	0.0474574142287016
GO:0008384	IkappaB kinase activity	0.0474574142287016
GO:0042732	D-xylose metabolic process	0.0474574142287016

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
abdomen element	2.68e-19	49
abdominal segment element	2.68e-19	49
abdominal segment of trunk	2.68e-19	49
abdomen	2.68e-19	49
liver	1.25e-18	22
epithelial sac	1.25e-18	22
digestive gland	1.25e-18	22
epithelium of foregut-midgut junction	1.25e-18	22
anatomical boundary	1.25e-18	22
hepatobiliary system	1.25e-18	22
foregut-midgut junction	1.25e-18	22
hepatic diverticulum	1.25e-18	22
liver primordium	1.25e-18	22
septum transversum	1.25e-18	22
liver bud	1.25e-18	22
digestive tract diverticulum	1.61e-17	23
sac	1.61e-17	23
exocrine gland	1.41e-15	25
exocrine system	1.41e-15	25
mesenchyme	2.98e-14	61
entire embryonic mesenchyme	2.98e-14	61
subdivision of trunk	1.35e-11	66
epithelial tube	2.15e-09	47
trunk mesenchyme	4.00e-09	45
kidney	4.68e-09	14
kidney mesenchyme	4.68e-09	14
upper urinary tract	4.68e-09	14
kidney rudiment	4.68e-09	14
kidney field	4.68e-09	14
trunk region element	4.32e-08	79

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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