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Coexpression cluster:C3390: Difference between revisions

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|ontology_enrichment_uberon=UBERON:0007023!4.96e-45!114;UBERON:0000477!2.84e-31!373;UBERON:0004111!3.54e-30!240;UBERON:0000025!4.38e-28!192;UBERON:0000119!3.40e-26!309;UBERON:0001049!3.96e-26!56;UBERON:0005068!3.96e-26!56;UBERON:0006241!3.96e-26!56;UBERON:0007135!3.96e-26!56;UBERON:0000483!1.94e-25!306;UBERON:0000073!3.15e-24!53;UBERON:0002616!3.15e-24!53;UBERON:0001017!7.98e-24!81;UBERON:0000955!8.74e-23!68;UBERON:0006238!8.74e-23!68;UBERON:0003075!1.49e-22!82;UBERON:0007284!1.49e-22!82;UBERON:0001016!1.25e-21!89;UBERON:0002346!5.04e-21!86;UBERON:0010314!3.92e-20!132;UBERON:0002780!5.83e-20!41;UBERON:0001890!5.83e-20!41;UBERON:0003080!5.83e-20!41;UBERON:0006240!5.83e-20!41;UBERON:0001893!7.60e-17!34;UBERON:0003528!7.78e-17!34;UBERON:0002020!7.78e-17!34;UBERON:0000481!2.37e-16!342;UBERON:0010371!2.53e-16!104;UBERON:0002791!1.53e-15!32;UBERON:0001869!1.79e-15!32;UBERON:0011216!1.99e-15!223;UBERON:0003056!9.56e-15!61;UBERON:0000468!2.48e-14!656;UBERON:0000467!1.31e-13!624;UBERON:0000480!1.79e-13!625;UBERON:0002619!2.51e-13!22;UBERON:0004121!2.84e-13!171;UBERON:0000924!2.84e-13!171;UBERON:0006601!2.84e-13!171;UBERON:0004638!1.95e-12!18;UBERON:0001986!1.95e-12!18;UBERON:0004852!1.95e-12!18;UBERON:0001950!3.15e-12!20;UBERON:0001009!5.97e-12!112;UBERON:0000956!2.70e-11!25;UBERON:0000203!2.70e-11!25;UBERON:0004872!2.81e-11!83;UBERON:0004535!6.86e-11!109;UBERON:0002049!1.69e-10!78;UBERON:0007798!1.69e-10!78;UBERON:0000487!2.89e-10!22;UBERON:0000064!3.37e-10!218;UBERON:0000922!3.63e-10!592;UBERON:0002050!1.03e-09!564;UBERON:0005423!1.35e-09!581;UBERON:0006914!1.39e-09!25;UBERON:0000055!1.61e-09!68;UBERON:0000923!2.02e-09!560;UBERON:0010316!2.02e-09!560;UBERON:0005291!2.02e-09!560;UBERON:0006598!2.02e-09!560;UBERON:0010317!2.02e-09!560;UBERON:0002532!2.02e-09!560;UBERON:0003914!9.14e-09!117;UBERON:0003103!4.77e-08!68;UBERON:0007500!5.10e-08!59;UBERON:0001981!5.10e-08!59;UBERON:0004537!5.10e-08!59;UBERON:0006965!5.10e-08!59;UBERON:0003076!2.32e-07!15;UBERON:0003057!2.32e-07!15;UBERON:0000125!3.02e-07!9;UBERON:0002308!3.02e-07!9;UBERON:0002420!4.63e-07!9;UBERON:0007245!4.63e-07!9;UBERON:0010009!4.63e-07!9;UBERON:0010011!4.63e-07!9;UBERON:0000454!4.63e-07!9;UBERON:0003915!5.16e-07!9;UBERON:0004700!5.16e-07!9;UBERON:0001917!5.16e-07!9;UBERON:0007100!8.21e-07!27
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}}
}}

Revision as of 16:06, 26 November 2012


Full id: C3390_Endothelial_lung_corpus_optic_adipose_thalamus_globus



Phase1 CAGE Peaks

Hg19::chr13:99630233..99630348,-p1@DOCK9
Hg19::chr8:17555164..17555204,-p1@MTUS1
Hg19::chr8:68864330..68864361,+p3@PREX2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
adult organism4.96e-45114
anatomical cluster2.84e-31373
anatomical conduit3.54e-30240
tube4.38e-28192
cell layer3.40e-26309
neural tube3.96e-2656
neural rod3.96e-2656
future spinal cord3.96e-2656
neural keel3.96e-2656
epithelium1.94e-25306
regional part of nervous system3.15e-2453
regional part of brain3.15e-2453
central nervous system7.98e-2481
brain8.74e-2368
future brain8.74e-2368
neural plate1.49e-2282
presumptive neural plate1.49e-2282
nervous system1.25e-2189
neurectoderm5.04e-2186
structure with developmental contribution from neural crest3.92e-20132
regional part of forebrain5.83e-2041
forebrain5.83e-2041
anterior neural tube5.83e-2041
future forebrain5.83e-2041
telencephalon7.60e-1734
brain grey matter7.78e-1734
gray matter7.78e-1734
multi-tissue structure2.37e-16342
ecto-epithelium2.53e-16104
regional part of telencephalon1.53e-1532
cerebral hemisphere1.79e-1532
organ system subdivision1.99e-15223
pre-chordal neural plate9.56e-1561
multi-cellular organism2.48e-14656
anatomical system1.31e-13624
anatomical group1.79e-13625
regional part of cerebral cortex2.51e-1322
ectoderm-derived structure2.84e-13171
ectoderm2.84e-13171
presumptive ectoderm2.84e-13171
blood vessel endothelium1.95e-1218
endothelium1.95e-1218
cardiovascular system endothelium1.95e-1218
neocortex3.15e-1220
circulatory system5.97e-12112
cerebral cortex2.70e-1125
pallium2.70e-1125
splanchnic layer of lateral plate mesoderm2.81e-1183
cardiovascular system6.86e-11109
vasculature1.69e-1078
vascular system1.69e-1078
simple squamous epithelium2.89e-1022
organ part3.37e-10218
embryo3.63e-10592
embryonic structure1.03e-09564
developing anatomical structure1.35e-09581
squamous epithelium1.39e-0925
vessel1.61e-0968
germ layer2.02e-09560
germ layer / neural crest2.02e-09560
embryonic tissue2.02e-09560
presumptive structure2.02e-09560
germ layer / neural crest derived structure2.02e-09560
epiblast (generic)2.02e-09560
epithelial tube9.14e-09117
compound organ4.77e-0868
epithelial tube open at both ends5.10e-0859
blood vessel5.10e-0859
blood vasculature5.10e-0859
vascular cord5.10e-0859
posterior neural tube2.32e-0715
chordal neural plate2.32e-0715
neural nucleus3.02e-079
nucleus of brain3.02e-079
basal ganglion4.63e-079
nuclear complex of neuraxis4.63e-079
aggregate regional part of brain4.63e-079
collection of basal ganglia4.63e-079
cerebral subcortex4.63e-079
endothelial tube5.16e-079
arterial system endothelium5.16e-079
endothelium of artery5.16e-079
primary circulatory organ8.21e-0727


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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