MCL coexpression mm9:675
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr15:99330556..99330579,- | p@chr15:99330556..99330579 - |
| Mm9::chr17:57220593..57220605,- | p@chr17:57220593..57220605 - |
| Mm9::chr18:82731161..82731209,+ | p@chr18:82731161..82731209 + |
| Mm9::chr18:82742205..82742279,+ | p@chr18:82742205..82742279 + |
| Mm9::chr18:82753528..82753641,+ | p3@Mbp |
| Mm9::chr18:82753680..82753700,+ | p8@Mbp |
| Mm9::chr18:82753753..82753769,+ | p14@Mbp |
| Mm9::chr18:82753804..82753847,+ | p7@Mbp |
| Mm9::chrX:133365641..133365660,+ | p8@Plp1 |
| Mm9::chrX:133366600..133366616,+ | p@chrX:133366600..133366616 + |
| Mm9::chrX:133367911..133367925,+ | p7@Plp1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0043209 | myelin sheath | 4.0221668700022e-06 |
| GO:0042552 | myelination | 4.08249937305224e-05 |
| GO:0007272 | ensheathment of neurons | 4.08249937305224e-05 |
| GO:0008366 | axon ensheathment | 4.08249937305224e-05 |
| GO:0001508 | regulation of action potential | 5.35752627084294e-05 |
| GO:0022010 | myelination in the central nervous system | 0.00104875128158972 |
| GO:0032291 | ensheathment of axons in the central nervous system | 0.00104875128158972 |
| GO:0019226 | transmission of nerve impulse | 0.00126698256405069 |
| GO:0019911 | structural constituent of myelin sheath | 0.0016313461917299 |
| GO:0007267 | cell-cell signaling | 0.00211767085705616 |
| GO:0042759 | long-chain fatty acid biosynthetic process | 0.00266932932585364 |
| GO:0014003 | oligodendrocyte development | 0.00305852272406418 |
| GO:0048709 | oligodendrocyte differentiation | 0.00479273862666581 |
| GO:0021782 | glial cell development | 0.00479273862666581 |
| GO:0065008 | regulation of biological quality | 0.00479273862666581 |
| GO:0007399 | nervous system development | 0.00479273862666581 |
| GO:0001676 | long-chain fatty acid metabolic process | 0.00604358963983972 |
| GO:0010001 | glial cell differentiation | 0.015482504587328 |
| GO:0042063 | gliogenesis | 0.0158243052701531 |
| GO:0044459 | plasma membrane part | 0.0214488081593173 |
| GO:0006633 | fatty acid biosynthetic process | 0.0216866710636755 |
| GO:0016053 | organic acid biosynthetic process | 0.0216866710636755 |
| GO:0046394 | carboxylic acid biosynthetic process | 0.0216866710636755 |
| GO:0048731 | system development | 0.0216866710636755 |
| GO:0048469 | cell maturation | 0.0216866710636755 |
| GO:0050877 | neurological system process | 0.0221309831303422 |
| GO:0021700 | developmental maturation | 0.024066419993433 |
| GO:0003008 | system process | 0.024066419993433 |
| GO:0005886 | plasma membrane | 0.0242892758101357 |
| GO:0048856 | anatomical structure development | 0.0242892758101357 |
| GO:0007275 | multicellular organismal development | 0.0294463485289453 |
| GO:0006631 | fatty acid metabolic process | 0.0365464137225575 |
| GO:0007268 | synaptic transmission | 0.0420490122393708 |
| GO:0032787 | monocarboxylic acid metabolic process | 0.0451609585678168 |
| GO:0032502 | developmental process | 0.0451609585678168 |
| GO:0007417 | central nervous system development | 0.0465238823906946 |
| GO:0008610 | lipid biosynthetic process | 0.0465238823906946 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| CNS neuron (sensu Vertebrata) | 6.68e-08 | 23 |
| neuroblast (sensu Vertebrata) | 6.68e-08 | 23 |
| neuron of the substantia nigra | 9.85e-08 | 3 |
| raphe nuclei neuron | 1.09e-07 | 3 |
| ectodermal cell | 1.98e-07 | 44 |
| neurectodermal cell | 1.98e-07 | 44 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.156602 |
| MA0004.1 | 0.330313 |
| MA0006.1 | 0.186435 |
| MA0007.1 | 1.53459 |
| MA0009.1 | 1.75966 |
| MA0014.1 | 0.00333639 |
| MA0017.1 | 0.207884 |
| MA0019.1 | 0.567591 |
| MA0024.1 | 0.70077 |
| MA0025.1 | 0.971686 |
| MA0027.1 | 2.37948 |
| MA0028.1 | 0.194782 |
| MA0029.1 | 1.62787 |
| MA0030.1 | 0.686088 |
| MA0031.1 | 0.651724 |
| MA0038.1 | 0.462726 |
| MA0040.1 | 0.755433 |
| MA0041.1 | 0.263922 |
| MA0042.1 | 0.252679 |
| MA0043.1 | 0.837621 |
| MA0046.1 | 0.778239 |
| MA0048.1 | 0.199479 |
| MA0050.1 | 0.365212 |
| MA0051.1 | 0.471092 |
| MA0052.1 | 0.76328 |
| MA0055.1 | 0.479469 |
| MA0056.1 | 0 |
| MA0057.1 | 0.406124 |
| MA0058.1 | 0.246908 |
| MA0059.1 | 0.257372 |
| MA0060.1 | 0.12537 |
| MA0061.1 | 0.147394 |
| MA0063.1 | 0 |
| MA0066.1 | 0.452472 |
| MA0067.1 | 1.08124 |
| MA0068.1 | 0.187364 |
| MA0069.1 | 0.76361 |
| MA0070.1 | 0.75417 |
| MA0071.1 | 0.364454 |
| MA0072.1 | 0.745922 |
| MA0073.1 | 2.58254e-05 |
| MA0074.1 | 0.419185 |
| MA0076.1 | 0.223625 |
| MA0077.1 | 0.724865 |
| MA0078.1 | 0.502121 |
| MA0081.1 | 0.277253 |
| MA0083.1 | 0.836845 |
| MA0084.1 | 1.4063 |
| MA0087.1 | 0.794721 |
| MA0088.1 | 0.12124 |
| MA0089.1 | 0 |
| MA0090.1 | 2.24963 |
| MA0091.1 | 1.62354 |
| MA0092.1 | 0.300264 |
| MA0093.1 | 0.20148 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.408523 |
| MA0101.1 | 0.265031 |
| MA0103.1 | 0.619698 |
| MA0105.1 | 0.0759118 |
| MA0106.1 | 0.509454 |
| MA0107.1 | 0.211681 |
| MA0108.2 | 0.589413 |
| MA0109.1 | 0 |
| MA0111.1 | 0.312463 |
| MA0113.1 | 0.482899 |
| MA0114.1 | 0.446898 |
| MA0115.1 | 0.84036 |
| MA0116.1 | 0.186271 |
| MA0117.1 | 0.808813 |
| MA0119.1 | 0.733279 |
| MA0122.1 | 0.828211 |
| MA0124.1 | 1.02871 |
| MA0125.1 | 0.955734 |
| MA0130.1 | 0 |
| MA0131.1 | 0.563262 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.873285 |
| MA0136.1 | 0.437601 |
| MA0139.1 | 0.103495 |
| MA0140.1 | 0.408417 |
| MA0141.1 | 0.233109 |
| MA0142.1 | 0.63775 |
| MA0143.1 | 0.49828 |
| MA0144.1 | 0.147954 |
| MA0145.1 | 0.3137 |
| MA0146.1 | 0.00490019 |
| MA0147.1 | 0.157258 |
| MA0148.1 | 0.344843 |
| MA0149.1 | 0.269772 |
| MA0062.2 | 0.0791588 |
| MA0035.2 | 0.412747 |
| MA0039.2 | 0.0387728 |
| MA0138.2 | 0.555696 |
| MA0002.2 | 0.699393 |
| MA0137.2 | 0.230686 |
| MA0104.2 | 0.11535 |
| MA0047.2 | 0.46201 |
| MA0112.2 | 0.57262 |
| MA0065.2 | 0.314773 |
| MA0150.1 | 0.316876 |
| MA0151.1 | 0 |
| MA0152.1 | 0.46211 |
| MA0153.1 | 0.889592 |
| MA0154.1 | 0.434137 |
| MA0155.1 | 0.154271 |
| MA0156.1 | 0.222905 |
| MA0157.1 | 0.606944 |
| MA0158.1 | 0 |
| MA0159.1 | 0.495113 |
| MA0160.1 | 0.347545 |
| MA0161.1 | 0 |
| MA0162.1 | 0.103104 |
| MA0163.1 | 0.0916052 |
| MA0164.1 | 0.437937 |
| MA0080.2 | 0.212408 |
| MA0018.2 | 0.446948 |
| MA0099.2 | 0.549696 |
| MA0079.2 | 1.32826e-05 |
| MA0102.2 | 1.45844 |
| MA0258.1 | 0.833943 |
| MA0259.1 | 0.14914 |
| MA0442.1 | 0 |
