MCL coexpression mm9:453
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr10:33816270..33816273,- | p6@Fam26e |
Mm9::chr13:49703399..49703432,+ | p1@Ogn |
Mm9::chr13:49718335..49718348,+ | p@chr13:49718335..49718348 + |
Mm9::chr14:47006937..47006958,- | p@chr14:47006937..47006958 - |
Mm9::chr14:47006973..47006987,- | p@chr14:47006973..47006987 - |
Mm9::chr15:54684962..54684979,- | p@chr15:54684962..54684979 - |
Mm9::chr17:80114052..80114087,- | p3@Cyp1b1 |
Mm9::chr1:172040854..172040860,- | p9@Ddr2 |
Mm9::chr1:95196851..95196860,+ | p@chr1:95196851..95196860 + |
Mm9::chr2:125860373..125860382,+ | p7@Fgf7 |
Mm9::chr2:125860383..125860401,+ | p1@Fgf7 |
Mm9::chr2:125860402..125860415,+ | p3@Fgf7 |
Mm9::chr2:125860501..125860530,+ | p2@Fgf7 |
Mm9::chr2:125860531..125860544,+ | p4@Fgf7 |
Mm9::chr2:125861402..125861426,+ | p@chr2:125861402..125861426 + |
Mm9::chr2:125861431..125861460,+ | p@chr2:125861431..125861460 + |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0008083 | growth factor activity | 0.00122733627288827 |
GO:0007500 | mesodermal cell fate determination | 0.0162561456218623 |
GO:0005102 | receptor binding | 0.0162561456218623 |
GO:0021978 | telencephalon regionalization | 0.0162561456218623 |
GO:0048522 | positive regulation of cellular process | 0.0162561456218623 |
GO:0044421 | extracellular region part | 0.0162561456218623 |
GO:0032331 | negative regulation of chondrocyte differentiation | 0.0162561456218623 |
GO:0032330 | regulation of chondrocyte differentiation | 0.0162561456218623 |
GO:0045662 | negative regulation of myoblast differentiation | 0.0162561456218623 |
GO:0001710 | mesodermal cell fate commitment | 0.0162561456218623 |
GO:0048333 | mesodermal cell differentiation | 0.0162561456218623 |
GO:0048518 | positive regulation of biological process | 0.0162561456218623 |
GO:0008284 | positive regulation of cell proliferation | 0.0162561456218623 |
GO:0021904 | dorsoventral neural tube patterning | 0.0170144388354342 |
GO:0030501 | positive regulation of bone mineralization | 0.0170144388354342 |
GO:0005125 | cytokine activity | 0.0194654964544927 |
GO:0045778 | positive regulation of ossification | 0.0210468324063134 |
GO:0021871 | forebrain regionalization | 0.0210468324063134 |
GO:0046852 | positive regulation of bone remodeling | 0.0210468324063134 |
GO:0045669 | positive regulation of osteoblast differentiation | 0.0210468324063134 |
GO:0045843 | negative regulation of striated muscle development | 0.0210468324063134 |
GO:0007167 | enzyme linked receptor protein signaling pathway | 0.0210468324063134 |
GO:0021532 | neural tube patterning | 0.0210468324063134 |
GO:0045661 | regulation of myoblast differentiation | 0.0210468324063134 |
GO:0005578 | proteinaceous extracellular matrix | 0.0210468324063134 |
GO:0051145 | smooth muscle cell differentiation | 0.0220739524444176 |
GO:0042127 | regulation of cell proliferation | 0.0250632321560463 |
GO:0045667 | regulation of osteoblast differentiation | 0.0273206722856267 |
GO:0016202 | regulation of striated muscle development | 0.028573663789643 |
GO:0050679 | positive regulation of epithelial cell proliferation | 0.0298721632535791 |
GO:0002062 | chondrocyte differentiation | 0.0298721632535791 |
GO:0030500 | regulation of bone mineralization | 0.0298721632535791 |
GO:0001658 | ureteric bud branching | 0.0347489098758318 |
GO:0005104 | fibroblast growth factor receptor binding | 0.0355966978373871 |
GO:0008283 | cell proliferation | 0.0365611800202646 |
GO:0030282 | bone mineralization | 0.0365611800202646 |
GO:0050678 | regulation of epithelial cell proliferation | 0.0365611800202646 |
GO:0030278 | regulation of ossification | 0.0365611800202646 |
GO:0001709 | cell fate determination | 0.0365611800202646 |
GO:0001707 | mesoderm formation | 0.0365611800202646 |
GO:0048332 | mesoderm morphogenesis | 0.0365611800202646 |
GO:0001649 | osteoblast differentiation | 0.0365611800202646 |
GO:0001934 | positive regulation of protein amino acid phosphorylation | 0.0365611800202646 |
GO:0001704 | formation of primary germ layer | 0.0365611800202646 |
GO:0033240 | positive regulation of amine metabolic process | 0.0365611800202646 |
GO:0045764 | positive regulation of amino acid metabolic process | 0.0365611800202646 |
GO:0007281 | germ cell development | 0.0365611800202646 |
GO:0030509 | BMP signaling pathway | 0.0376583279657835 |
GO:0046850 | regulation of bone remodeling | 0.0376583279657835 |
GO:0050673 | epithelial cell proliferation | 0.0391437993405773 |
GO:0001657 | ureteric bud development | 0.0391437993405773 |
GO:0050381 | unspecific monooxygenase activity | 0.0391437993405773 |
GO:0045445 | myoblast differentiation | 0.0416472564852497 |
GO:0042475 | odontogenesis of dentine-containing teeth | 0.0416472564852497 |
GO:0006468 | protein amino acid phosphorylation | 0.0416472564852497 |
GO:0030218 | erythrocyte differentiation | 0.0416472564852497 |
GO:0042476 | odontogenesis | 0.0416472564852497 |
GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | 0.0416472564852497 |
GO:0005615 | extracellular space | 0.0419100510557126 |
GO:0009953 | dorsal/ventral pattern formation | 0.0455312993014895 |
GO:0016310 | phosphorylation | 0.0461018634925893 |
GO:0001656 | metanephros development | 0.0461018634925893 |
GO:0045597 | positive regulation of cell differentiation | 0.0463732300747337 |
GO:0051216 | cartilage development | 0.0476229337557569 |
GO:0007498 | mesoderm development | 0.0478619088067146 |
GO:0033238 | regulation of amine metabolic process | 0.0485354375447023 |
GO:0001932 | regulation of protein amino acid phosphorylation | 0.0485354375447023 |
GO:0006521 | regulation of amino acid metabolic process | 0.0485354375447023 |
GO:0042325 | regulation of phosphorylation | 0.0490433248316235 |
GO:0051174 | regulation of phosphorus metabolic process | 0.0490433248316235 |
GO:0019220 | regulation of phosphate metabolic process | 0.0490433248316235 |
GO:0048754 | branching morphogenesis of a tube | 0.0490433248316235 |
GO:0008201 | heparin binding | 0.0490433248316235 |
GO:0006793 | phosphorus metabolic process | 0.0490433248316235 |
GO:0006796 | phosphate metabolic process | 0.0490433248316235 |
GO:0007369 | gastrulation | 0.0490433248316235 |
GO:0004714 | transmembrane receptor protein tyrosine kinase activity | 0.0490433248316235 |
GO:0001763 | morphogenesis of a branching structure | 0.0490433248316235 |
GO:0042692 | muscle cell differentiation | 0.0490433248316235 |
GO:0048741 | skeletal muscle fiber development | 0.0490433248316235 |
GO:0030324 | lung development | 0.0490433248316235 |
GO:0048747 | muscle fiber development | 0.0490433248316235 |
GO:0030323 | respiratory tube development | 0.0490433248316235 |
GO:0021915 | neural tube development | 0.0490433248316235 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
surface structure | 5.19e-09 | 22 |
lung | 7.96e-09 | 14 |
respiratory tube | 7.96e-09 | 14 |
respiration organ | 7.96e-09 | 14 |
pair of lungs | 7.96e-09 | 14 |
lung primordium | 7.96e-09 | 14 |
lung bud | 7.96e-09 | 14 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.000187754 |
MA0004.1 | 1.18327 |
MA0006.1 | 1.69731 |
MA0007.1 | 0.210531 |
MA0009.1 | 0.599391 |
MA0014.1 | 0.14854 |
MA0017.1 | 0.122138 |
MA0019.1 | 0.434009 |
MA0024.1 | 0.558971 |
MA0025.1 | 0.819843 |
MA0027.1 | 2.21717 |
MA0028.1 | 0.112137 |
MA0029.1 | 0.53905 |
MA0030.1 | 0.545058 |
MA0031.1 | 0.512616 |
MA0038.1 | 0.897243 |
MA0040.1 | 0.611015 |
MA0041.1 | 0.166538 |
MA0042.1 | 0.15744 |
MA0043.1 | 0.689898 |
MA0046.1 | 0.632833 |
MA0048.1 | 1.39913 |
MA0050.1 | 0.251816 |
MA0051.1 | 0.345658 |
MA0052.1 | 0.618515 |
MA0055.1 | 0.0964477 |
MA0056.1 | 0 |
MA0057.1 | 0.381022 |
MA0058.1 | 2.08874 |
MA0059.1 | 1.50458 |
MA0060.1 | 0.0623353 |
MA0061.1 | 0.267107 |
MA0063.1 | 0 |
MA0066.1 | 1.57697 |
MA0067.1 | 0.92691 |
MA0068.1 | 0.203932 |
MA0069.1 | 0.618831 |
MA0070.1 | 0.609808 |
MA0071.1 | 1.29438 |
MA0072.1 | 0.601934 |
MA0073.1 | 0.00253329 |
MA0074.1 | 0.299171 |
MA0076.1 | 0.134359 |
MA0077.1 | 0.581866 |
MA0078.1 | 0.37382 |
MA0081.1 | 0.177433 |
MA0083.1 | 0.68915 |
MA0084.1 | 1.24749 |
MA0087.1 | 0.648637 |
MA0088.1 | 0.120779 |
MA0089.1 | 0 |
MA0090.1 | 0.570974 |
MA0091.1 | 1.22165 |
MA0092.1 | 0.196497 |
MA0093.1 | 1.79708 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.289731 |
MA0101.1 | 0.167439 |
MA0103.1 | 0.128989 |
MA0105.1 | 0.303578 |
MA0106.1 | 0.380511 |
MA0107.1 | 0.394565 |
MA0108.2 | 0.454274 |
MA0109.1 | 0 |
MA0111.1 | 0.206727 |
MA0113.1 | 0.356344 |
MA0114.1 | 0.0762439 |
MA0115.1 | 0.692537 |
MA0116.1 | 0.105729 |
MA0117.1 | 0.662171 |
MA0119.1 | 0.16785 |
MA0122.1 | 0.680832 |
MA0124.1 | 0.875485 |
MA0125.1 | 1.88564 |
MA0130.1 | 0 |
MA0131.1 | 0.43 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.724328 |
MA0136.1 | 0.315568 |
MA0139.1 | 0.181201 |
MA0140.1 | 0.289637 |
MA0141.1 | 0.141822 |
MA0142.1 | 0.499475 |
MA0143.1 | 0.37032 |
MA0144.1 | 0.0778672 |
MA0145.1 | 0.4773 |
MA0146.1 | 0.0186621 |
MA0147.1 | 1.49813 |
MA0148.1 | 0.660829 |
MA0149.1 | 0.171305 |
MA0062.2 | 0.0332891 |
MA0035.2 | 1.45004 |
MA0039.2 | 0.000979253 |
MA0138.2 | 0.423003 |
MA0002.2 | 0.413675 |
MA0137.2 | 0.139909 |
MA0104.2 | 1.19482 |
MA0047.2 | 0.337465 |
MA0112.2 | 0.135501 |
MA0065.2 | 0.0494003 |
MA0150.1 | 0.604793 |
MA0151.1 | 0 |
MA0152.1 | 0.337555 |
MA0153.1 | 0.740107 |
MA0154.1 | 0.215016 |
MA0155.1 | 0.16166 |
MA0156.1 | 0.133796 |
MA0157.1 | 0.47062 |
MA0158.1 | 0 |
MA0159.1 | 0.301936 |
MA0160.1 | 0.23657 |
MA0161.1 | 0 |
MA0162.1 | 0.00698895 |
MA0163.1 | 0.00566486 |
MA0164.1 | 0.315868 |
MA0080.2 | 0.125629 |
MA0018.2 | 0.865591 |
MA0099.2 | 0.417463 |
MA0079.2 | 4.69272e-05 |
MA0102.2 | 1.29919 |
MA0258.1 | 0.522754 |
MA0259.1 | 1.44117 |
MA0442.1 | 0 |