MCL coexpression mm9:401
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Short description | |
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Mm9::chr12:106575390..106575401,+ | p2@uc007oyh.1 |
Mm9::chr12:91051249..91051258,+ | p4@LOC100505240 p5@Nrxn3 |
Mm9::chr15:4325574..4325623,+ | p2@Plcxd3 |
Mm9::chr1:107253057..107253093,- | p2@Rnf152 |
Mm9::chr1:84692551..84692569,- | p2@Dner |
Mm9::chr1:84692741..84692753,- | p7@Dner |
Mm9::chr1:84692757..84692777,- | p3@Dner |
Mm9::chr3:97692834..97692852,- | p14@Pde4dip |
Mm9::chr4:154719787..154719798,- | p5@Prkcz |
Mm9::chr4:49857757..49857759,- | p@chr4:49857757..49857759 - |
Mm9::chr5:151062497..151062511,+ | p7@Fry |
Mm9::chr5:27231364..27231415,+ | p5@Dpp6 |
Mm9::chr5:69732910..69732924,- | p2@Kctd8 |
Mm9::chr5:69732938..69732953,- | p3@Kctd8 |
Mm9::chr6:63206101..63206120,+ | p3@Grid2 |
Mm9::chr7:148667927..148667985,+ | p@chr7:148667927..148667985 + |
Mm9::chr9:107302127..107302180,+ | p1@Cacna2d2 |
Mm9::chr9:107302189..107302203,+ | p3@Cacna2d2 |
Mm9::chr9:64233453..64233464,+ | p2@Megf11 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0060134 | prepulse inhibition | 0.000470719502175586 |
GO:0048585 | negative regulation of response to stimulus | 0.000470719502175586 |
GO:0032102 | negative regulation of response to external stimulus | 0.000470719502175586 |
GO:0032101 | regulation of response to external stimulus | 0.000604812928979771 |
GO:0001964 | startle response | 0.00088618439085382 |
GO:0005216 | ion channel activity | 0.00103108625907904 |
GO:0022838 | substrate specific channel activity | 0.00103108625907904 |
GO:0004970 | ionotropic glutamate receptor activity | 0.00103108625907904 |
GO:0022803 | passive transmembrane transporter activity | 0.00103108625907904 |
GO:0015267 | channel activity | 0.00103108625907904 |
GO:0008066 | glutamate receptor activity | 0.00488962419320737 |
GO:0048583 | regulation of response to stimulus | 0.00488962419320737 |
GO:0005261 | cation channel activity | 0.00488962419320737 |
GO:0050905 | neuromuscular process | 0.00488962419320737 |
GO:0015075 | ion transmembrane transporter activity | 0.00488962419320737 |
GO:0022836 | gated channel activity | 0.00546079721263632 |
GO:0043025 | cell soma | 0.00578478784144084 |
GO:0006811 | ion transport | 0.00578478784144084 |
GO:0046873 | metal ion transmembrane transporter activity | 0.00578478784144084 |
GO:0045179 | apical cortex | 0.00578478784144084 |
GO:0022891 | substrate-specific transmembrane transporter activity | 0.00578478784144084 |
GO:0048741 | skeletal muscle fiber development | 0.00578478784144084 |
GO:0048747 | muscle fiber development | 0.00578478784144084 |
GO:0005262 | calcium channel activity | 0.00607398701555443 |
GO:0022857 | transmembrane transporter activity | 0.0087235199092231 |
GO:0004700 | atypical protein kinase C activity | 0.00945423206658046 |
GO:0030001 | metal ion transport | 0.0102199130653923 |
GO:0007519 | skeletal muscle development | 0.0102199130653923 |
GO:0044425 | membrane part | 0.0102199130653923 |
GO:0022892 | substrate-specific transporter activity | 0.0102199130653923 |
GO:0006816 | calcium ion transport | 0.0110408241806702 |
GO:0007220 | Notch receptor processing | 0.0115191890431605 |
GO:0045211 | postsynaptic membrane | 0.0115985942305008 |
GO:0022843 | voltage-gated cation channel activity | 0.0125769220468412 |
GO:0008324 | cation transmembrane transporter activity | 0.0125769220468412 |
GO:0006812 | cation transport | 0.0125769220468412 |
GO:0044456 | synapse part | 0.0125769220468412 |
GO:0014706 | striated muscle development | 0.0125769220468412 |
GO:0060024 | rhythmic synaptic transmission | 0.0125987378246049 |
GO:0015674 | di-, tri-valent inorganic cation transport | 0.0141581877252212 |
GO:0004972 | N-methyl-D-aspartate selective glutamate receptor activity | 0.0175386307102534 |
GO:0005112 | Notch binding | 0.0175386307102534 |
GO:0004274 | dipeptidyl-peptidase IV activity | 0.0192244577366487 |
GO:0007517 | muscle development | 0.0192244577366487 |
GO:0022832 | voltage-gated channel activity | 0.0192244577366487 |
GO:0005244 | voltage-gated ion channel activity | 0.0192244577366487 |
GO:0016021 | integral to membrane | 0.0225795367769959 |
GO:0051605 | protein maturation via proteolysis | 0.0225795367769959 |
GO:0031224 | intrinsic to membrane | 0.0225795367769959 |
GO:0051604 | protein maturation | 0.0245271979983456 |
GO:0008239 | dipeptidyl-peptidase activity | 0.0282851177934602 |
GO:0016806 | dipeptidyl-peptidase and tripeptidyl-peptidase activity | 0.0282851177934602 |
GO:0005891 | voltage-gated calcium channel complex | 0.032247943507392 |
GO:0044459 | plasma membrane part | 0.032247943507392 |
GO:0004697 | protein kinase C activity | 0.033400420144724 |
GO:0016020 | membrane | 0.0342180268267809 |
GO:0005515 | protein binding | 0.0342180268267809 |
GO:0001565 | phorbol ester receptor activity | 0.0352681340964569 |
GO:0005234 | extracellular-glutamate-gated ion channel activity | 0.0352681340964569 |
GO:0051969 | regulation of transmission of nerve impulse | 0.0394518387140763 |
GO:0007528 | neuromuscular junction development | 0.0394518387140763 |
GO:0050804 | regulation of synaptic transmission | 0.0394518387140763 |
GO:0005245 | voltage-gated calcium channel activity | 0.0407557438701065 |
GO:0031644 | regulation of neurological process | 0.0496031471657009 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
CNS neuron (sensu Vertebrata) | 3.88e-19 | 23 |
neuroblast (sensu Vertebrata) | 3.88e-19 | 23 |
neuron | 1.82e-15 | 33 |
neuronal stem cell | 1.82e-15 | 33 |
neuroblast | 1.82e-15 | 33 |
electrically signaling cell | 1.82e-15 | 33 |
electrically responsive cell | 1.68e-11 | 39 |
electrically active cell | 1.68e-11 | 39 |
ectodermal cell | 1.75e-10 | 44 |
neurectodermal cell | 1.75e-10 | 44 |
neural cell | 3.40e-10 | 43 |
non-terminally differentiated cell | 8.64e-08 | 49 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 1.65122 |
MA0004.1 | 0.178381 |
MA0006.1 | 0.952171 |
MA0007.1 | 0.168178 |
MA0009.1 | 0.535932 |
MA0014.1 | 1.89506 |
MA0017.1 | 0.0906268 |
MA0019.1 | 0.376509 |
MA0024.1 | 0.496718 |
MA0025.1 | 0.751694 |
MA0027.1 | 2.14278 |
MA0028.1 | 0.280241 |
MA0029.1 | 0.477444 |
MA0030.1 | 0.483253 |
MA0031.1 | 0.451927 |
MA0038.1 | 0.285714 |
MA0040.1 | 0.547233 |
MA0041.1 | 1.89679 |
MA0042.1 | 1.82974 |
MA0043.1 | 0.624178 |
MA0046.1 | 0.568473 |
MA0048.1 | 1.45051 |
MA0050.1 | 0.205672 |
MA0051.1 | 0.2928 |
MA0052.1 | 0.554531 |
MA0055.1 | 1.4457 |
MA0056.1 | 0 |
MA0057.1 | 0.262449 |
MA0058.1 | 0.117003 |
MA0059.1 | 0.392739 |
MA0060.1 | 0.369051 |
MA0061.1 | 0.0537092 |
MA0063.1 | 0 |
MA0066.1 | 0.277072 |
MA0067.1 | 0.857286 |
MA0068.1 | 0.0481248 |
MA0069.1 | 0.554839 |
MA0070.1 | 0.54606 |
MA0071.1 | 0.592012 |
MA0072.1 | 0.538403 |
MA0073.1 | 0.0405835 |
MA0074.1 | 0.249359 |
MA0076.1 | 0.101055 |
MA0077.1 | 0.518913 |
MA0078.1 | 0.319336 |
MA0081.1 | 0.429201 |
MA0083.1 | 0.623446 |
MA0084.1 | 1.1752 |
MA0087.1 | 0.583879 |
MA0088.1 | 0.705351 |
MA0089.1 | 0 |
MA0090.1 | 0.471234 |
MA0091.1 | 0.549843 |
MA0092.1 | 0.471747 |
MA0093.1 | 0.0864726 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.2406 |
MA0101.1 | 0.12981 |
MA0103.1 | 0.0964586 |
MA0105.1 | 0.672551 |
MA0106.1 | 0.325663 |
MA0107.1 | 0.093115 |
MA0108.2 | 0.395878 |
MA0109.1 | 0 |
MA0111.1 | 0.494436 |
MA0113.1 | 0.302851 |
MA0114.1 | 0.0527257 |
MA0115.1 | 0.626759 |
MA0116.1 | 0.951399 |
MA0117.1 | 0.597086 |
MA0119.1 | 0.130171 |
MA0122.1 | 0.615314 |
MA0124.1 | 0.80652 |
MA0125.1 | 0.736412 |
MA0130.1 | 0 |
MA0131.1 | 0.372683 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.657882 |
MA0136.1 | 0.264624 |
MA0139.1 | 1.25918 |
MA0140.1 | 0.240513 |
MA0141.1 | 0.708661 |
MA0142.1 | 0.439269 |
MA0143.1 | 0.31603 |
MA0144.1 | 0.0540242 |
MA0145.1 | 0.0816911 |
MA0146.1 | 1.27781 |
MA0147.1 | 0.215066 |
MA0148.1 | 0.189643 |
MA0149.1 | 0.823515 |
MA0062.2 | 0.0201154 |
MA0035.2 | 0.68369 |
MA0039.2 | 0.875155 |
MA0138.2 | 2.57183 |
MA0002.2 | 0.560759 |
MA0137.2 | 0.105829 |
MA0104.2 | 0.337396 |
MA0047.2 | 0.285109 |
MA0112.2 | 0.0816855 |
MA0065.2 | 0.0821754 |
MA0150.1 | 0.168102 |
MA0151.1 | 0 |
MA0152.1 | 0.285194 |
MA0153.1 | 0.67335 |
MA0154.1 | 0.494059 |
MA0155.1 | 1.9396 |
MA0156.1 | 0.100572 |
MA0157.1 | 0.411541 |
MA0158.1 | 0 |
MA0159.1 | 0.0638985 |
MA0160.1 | 1.06584 |
MA0161.1 | 0 |
MA0162.1 | 1.18735 |
MA0163.1 | 0.853384 |
MA0164.1 | 0.264905 |
MA0080.2 | 0.0935932 |
MA0018.2 | 2.11047 |
MA0099.2 | 0.360735 |
MA0079.2 | 1.88076 |
MA0102.2 | 1.22663 |
MA0258.1 | 0.401444 |
MA0259.1 | 0.774997 |
MA0442.1 | 0 |